JP2005507944A - ウイルスの抑制における改善およびその関連 - Google Patents

ウイルスの抑制における改善およびその関連 Download PDF

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Publication number
JP2005507944A
JP2005507944A JP2003541742A JP2003541742A JP2005507944A JP 2005507944 A JP2005507944 A JP 2005507944A JP 2003541742 A JP2003541742 A JP 2003541742A JP 2003541742 A JP2003541742 A JP 2003541742A JP 2005507944 A JP2005507944 A JP 2005507944A
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Japan
Prior art keywords
pharmaceutical composition
ribonucleoside
rna
composition according
general formula
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
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JP2003541742A
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English (en)
Japanese (ja)
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JP2005507944A5 (https=
Inventor
ロークス，デイビッド
ブラウン，ダニエル
バルザリニ，ヤン
圭 森山
和雄 根岸
キャメロン，クレイグ
アーノルド，ジェーミー
カストロ，クリスチャン
コルニーバ，ビクトリア
グラシ，ジェイソン
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Medical Research Council
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Medical Research Council
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Publication date
Priority claimed from GB0126701A external-priority patent/GB0126701D0/en
Application filed by Medical Research Council filed Critical Medical Research Council
Publication of JP2005507944A publication Critical patent/JP2005507944A/ja
Publication of JP2005507944A5 publication Critical patent/JP2005507944A5/ja
Withdrawn legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Genetics & Genomics (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Saccharide Compounds (AREA)
JP2003541742A 2001-11-07 2002-11-07 ウイルスの抑制における改善およびその関連 Withdrawn JP2005507944A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB0126701A GB0126701D0 (en) 2001-11-07 2001-11-07 Improvements in or relating to induction of mutations in viruses
US10/207,005 US7049303B2 (en) 2001-11-07 2002-07-30 Inhibition of viruses
PCT/GB2002/005031 WO2003039450A2 (en) 2001-11-07 2002-11-07 Improvements in or relating to inhibition of viruses

Publications (2)

Publication Number Publication Date
JP2005507944A true JP2005507944A (ja) 2005-03-24
JP2005507944A5 JP2005507944A5 (https=) 2006-01-12

Family

ID=26246745

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003541742A Withdrawn JP2005507944A (ja) 2001-11-07 2002-11-07 ウイルスの抑制における改善およびその関連

Country Status (5)

Country Link
US (2) US7049303B2 (https=)
EP (1) EP1441744A2 (https=)
JP (1) JP2005507944A (https=)
AU (1) AU2002337388A1 (https=)
WO (1) WO2003039450A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006505537A (ja) * 2002-09-30 2006-02-16 ジェネラブス テクノロジーズ，インコーポレイテッド Ｃ型肝炎ウイルスの感染を治療するためのヌクレオシド誘導体

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7094768B2 (en) * 2002-09-30 2006-08-22 Genelabs Technologies, Inc. Nucleoside derivatives for treating hepatitis C virus infection
EP1682564A1 (en) * 2003-10-27 2006-07-26 Genelabs Technologies, Inc. METHODS FOR PREPARING 7-(2 -SUBSTITUTED-s-D-RIBOFURANO SYL)-4-(NR2R3)-5-(SUBSTITUTED ETHYN-1-YL)-PYRROLO 2,3-D|PYRIMIDINE DERIVATIVES
KR101170925B1 (ko) 2004-06-18 2012-08-07 노바티스 백신즈 앤드 다이아그노스틱스 인코포레이티드 암 치료용 키네신 방추 단백질 (ｋｓｐ) 억제제로서의ｎ-(1-(1-벤질-4-페닐-1ｈ-이미다졸-2-일)-2,2-디메틸프로필)벤자미드 유도체 및 관련 화합물
EP1858889A1 (en) * 2005-03-08 2007-11-28 Biota Scientific Management Pty. Ltd. Bicyclic nucleosides and nucleotides as therapeutic agents
US8415321B2 (en) 2008-04-15 2013-04-09 Raymond F. Schinazi Nucleoside derivatives for treatment of Caliciviridae infections, including Norovirus infections
ES2540964T3 (es) 2009-06-08 2015-07-15 Takeda Pharmaceutical Company Limited Compuestos de dihidropirrolonaftiridinona como inhibidores de JAK
BR112015009636A8 (pt) * 2012-10-29 2018-04-17 Cocrystal Pharma Inc composto, métodos para o tratamento de um hospedeiro infectado, métodos para a prevenção de uma infecção, métodos para a redução da atividade biológica de uma infecção e uso de um composto
DK3236972T3 (en) 2014-12-26 2021-10-04 Univ Emory Antivirale N4-hydroxycytidin-derivativer
JP6804790B1 (ja) 2017-12-07 2020-12-23 エモリー ユニバーシティー Ｎ４−ヒドロキシシチジンおよび誘導体ならびにそれらに関連する抗ウイルス用途
WO2023152709A1 (en) * 2022-02-14 2023-08-17 Arbutus Biopharma Corporation Rna polymerase inhibitors and methods using same

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8802687D0 (sv) 1988-07-20 1988-07-20 Astra Ab Nucleoside derivatives
EP0375183A1 (en) 1988-12-05 1990-06-27 Schering Corporation Antiviral dimers and trimers
DK62592D0 (https=) * 1992-05-14 1992-05-14 Novo Nordisk As
US5773424A (en) 1994-12-16 1998-06-30 Research Corporation Technologies, Inc. Treatment of toxoplasmosis
EP0831852B1 (en) 1995-06-07 2006-11-29 Emory University Nucleosides with anti-hepatitis b virus activity
ATE271063T1 (de) 1996-10-16 2004-07-15 Icn Pharmaceuticals Purin-l-nukleoside, deren analoga und verwendungen
EP0948256A4 (en) 1996-10-28 2007-10-24 Univ Washington INDUCTION OF VIRAL MUTATIONS BY INTRODUCTION TO ERROR-CODED RIBONUCLEOSIDE ANALOGUES IN VIRAL RNA
KR100719606B1 (ko) 1998-02-25 2007-05-17 에모리 유니버시티 2'-플루오로뉴클레오사이드
IL133680A0 (en) 1999-09-10 2001-04-30 Can Fite Technologies Ltd Pharmaceutical compositions comprising an adenosine receptor agonist or antagonist
AU2603101A (en) 1999-12-22 2001-07-03 Inspire Pharmaceuticals, Inc. Method of treating gastrointestinal tract disease with purinergic receptor agonists

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006505537A (ja) * 2002-09-30 2006-02-16 ジェネラブス テクノロジーズ，インコーポレイテッド Ｃ型肝炎ウイルスの感染を治療するためのヌクレオシド誘導体

Also Published As

Publication number Publication date
EP1441744A2 (en) 2004-08-04
US20050043268A1 (en) 2005-02-24
WO2003039450A3 (en) 2003-08-21
AU2002337388A1 (en) 2003-05-19
US7049303B2 (en) 2006-05-23
US20030130226A1 (en) 2003-07-10
WO2003039450A2 (en) 2003-05-15

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