JP2005505757A5 - - Google Patents

Download PDF

Info

Publication number
JP2005505757A5
JP2005505757A5 JP2003528210A JP2003528210A JP2005505757A5 JP 2005505757 A5 JP2005505757 A5 JP 2005505757A5 JP 2003528210 A JP2003528210 A JP 2003528210A JP 2003528210 A JP2003528210 A JP 2003528210A JP 2005505757 A5 JP2005505757 A5 JP 2005505757A5
Authority
JP
Japan
Prior art keywords
reagent
ctgf
sample
region
terminal fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003528210A
Other languages
English (en)
Japanese (ja)
Other versions
JP2005505757A (ja
JP4226471B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/029500 external-priority patent/WO2003024308A2/en
Publication of JP2005505757A publication Critical patent/JP2005505757A/ja
Publication of JP2005505757A5 publication Critical patent/JP2005505757A5/ja
Application granted granted Critical
Publication of JP4226471B2 publication Critical patent/JP4226471B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2003528210A 2001-09-18 2002-09-18 結合組織増殖因子の分析方法 Expired - Fee Related JP4226471B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32330501P 2001-09-18 2001-09-18
PCT/US2002/029500 WO2003024308A2 (en) 2001-09-18 2002-09-18 Methods of assaying connective tissue growth factor

Publications (3)

Publication Number Publication Date
JP2005505757A JP2005505757A (ja) 2005-02-24
JP2005505757A5 true JP2005505757A5 (https=) 2006-01-05
JP4226471B2 JP4226471B2 (ja) 2009-02-18

Family

ID=23258613

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003528210A Expired - Fee Related JP4226471B2 (ja) 2001-09-18 2002-09-18 結合組織増殖因子の分析方法

Country Status (6)

Country Link
US (2) US20030113816A1 (https=)
EP (1) EP1434993B1 (https=)
JP (1) JP4226471B2 (https=)
CN (1) CN1589403B (https=)
AU (1) AU2002326939A1 (https=)
WO (1) WO2003024308A2 (https=)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003049773A1 (en) * 2001-12-11 2003-06-19 Fibrogen, Inc. Methods for inhibiting ocular processes
WO2003102161A2 (en) * 2002-06-04 2003-12-11 Metabolex, Inc. Methods of diagnosing & treating diabetes and insulin resistance
US7405274B2 (en) * 2003-06-04 2008-07-29 Fibrogen, Inc. Connective tissue growth factor antibodies
CA2565070A1 (en) 2004-04-28 2005-11-24 Fibrogen, Inc. Anti-ctgf agents for the treatment of pancreatic cancer
JP2007535562A (ja) * 2004-04-29 2007-12-06 ジェンザイム・コーポレイション 多嚢胞性疾患の処置のための方法および組成物
CN101120252A (zh) 2005-02-18 2008-02-06 儿童医疗中心有限公司 作为生物标记物用于上皮来源的癌症的诊断和预后的cyr61
AU2006244144A1 (en) * 2005-05-05 2006-11-16 Fibrogen, Inc. Diagnostic marker for diabetic vascular complications
US20110111394A1 (en) 2006-10-16 2011-05-12 Bayer Schering Pharma Aktiengesellschaft Ctgf as a biomarker, therapeutic and diagnostic target
JP2008295328A (ja) * 2007-05-30 2008-12-11 Fujifilm Corp 卵巣癌の検出方法、及び抑制方法
JP5104622B2 (ja) * 2008-07-29 2012-12-19 Ｊｎｃ株式会社 磁性粒子を用いた測定対象物質の濃度測定法
CA2746527A1 (en) 2008-09-22 2010-03-25 Rxi Pharmaceuticals Corporation Rna interference in skin indications
EP2221387A1 (en) 2009-02-19 2010-08-25 Université de la Méditerranée Fibrosis susceptibility gene and uses thereof
CN106074591B (zh) 2010-03-24 2020-01-14 菲奥医药公司 眼部症候中的rna干扰
BR112012024049A2 (pt) * 2010-03-24 2017-03-01 Rxi Pharmaceuticals Corp interferência de rna em indicações dérmicas e fibróticas
US20130109585A1 (en) * 2010-04-15 2013-05-02 Digital Sensing Limited Microarrays
US20140134181A1 (en) 2010-11-05 2014-05-15 Kenneth E. Lipson Treatment Method For Lung Remodeling Diseases
US9102721B2 (en) 2011-01-21 2015-08-11 Fibrogen, Inc. Therapeutic method
CN104302780B (zh) 2011-08-05 2017-04-12 艾克斯-马赛大学 纤维变性易感性il22ra2基因及其用途
JP5445885B2 (ja) * 2011-10-13 2014-03-19 特種東海製紙株式会社 電気化学素子用セパレータ及びその製造方法
WO2013148159A1 (en) * 2012-03-30 2013-10-03 Fibrogen Inc Therapeutic methods for peritoneal carcinomatosis
ES2718472T3 (es) 2012-05-03 2019-07-02 Fibrogen Inc Métodos para tratar fibrosis pulmonar idiopática
US9377473B2 (en) * 2013-03-15 2016-06-28 Harald Jueppner Immunoassays and methods of detecting and measuring intact fibroblast growth factor 23, and C-terminal and N-terminal fragments thereof
US9631013B2 (en) 2014-01-28 2017-04-25 Fibrogen, Inc. Therapeutic method for pancreatic cancer
CN109402127B (zh) * 2018-09-29 2021-12-10 复旦大学附属眼耳鼻喉科医院 一组与结缔组织生长因子特异性结合的高亲和力核酸适配体及其应用

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
ATE300615T1 (de) 1990-08-29 2005-08-15 Genpharm Int Transgene mäuse fähig zur produktion heterologer antikörper
US5408040A (en) * 1991-08-30 1995-04-18 University Of South Florida Connective tissue growth factor(CTGF)
US5770209A (en) * 1991-08-30 1998-06-23 University Of South Florida Acceleration of wound healing using connective tissue growth factor
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
ES2136092T3 (es) 1991-09-23 1999-11-16 Medical Res Council Procedimientos para la produccion de anticuerpos humanizados.
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
US5314804A (en) * 1992-03-24 1994-05-24 Serim Research Corporation Test for Helicobacter pylori
US5461854A (en) 1993-07-07 1995-10-31 Griffin, Jr.; Arthur T. Combustor cooling for gas turbine engines
US5916756A (en) * 1993-12-14 1999-06-29 University Of South Florida Assay of connective tissue growth factor for detection of cell proliferative disorders
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7026299B2 (en) * 1994-07-12 2006-04-11 Human Genome Sciences, Inc. Connective tissue growth factor-2
CA2228970A1 (en) * 1995-08-18 1997-02-27 Donald W. Landry Detection of organic compounds through regulation of antibody-catalyzed reactions
US5876730A (en) 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
WO1999033878A1 (en) * 1997-12-25 1999-07-08 Japan Tobacco Inc. Monoclonal antibody against connective tissue growth factor and medicinal uses thereof
EP1112088B1 (en) 1998-09-08 2010-10-27 Henry Ford Health System Method for detecting connective tissue growth factor for diagnosing a renal disorder
MXPA01004502A (es) 1998-11-06 2002-09-18 Fibrogen Inc Factor de crecimiento de tejido conector (ctgf) y metodos de uso.
DK1140969T3 (da) * 1998-12-14 2007-09-17 Univ Miami Bindevævsvækstfaktorfragmenter og fremgangsmåder og anvendelser deraf
US7115390B1 (en) * 1998-12-14 2006-10-03 Fibrogen, Inc. Connective tissue growth factor fragments and methods and uses thereof
AU6929500A (en) 1999-08-27 2001-03-26 Fibrogen, Inc. Connective tissue growth factor receptor, its agonists and antagonists, and their therapeutic and diagnostic uses

Similar Documents

Publication Publication Date Title
JP2005505757A5 (https=)
CN1759319B (zh) 生物液中肾上腺髓质素原中间区域部分肽在制备免疫诊断剂中的用途
JP5553835B2 (ja) 原発性慢性腎臓疾患の進行についての予後バイオマーカー
AU2009224114B2 (en) Biomarkers
EP1970709B1 (en) The use of BNP-type peptides for predicting the need for dialysis
JP5810089B2 (ja) 体液ホメオスタシスのバイオマーカーとしてのｍｃａｍ
EP2095107A2 (en) Methods and compositions for monitoring and risk prediction in cardiorenal syndrome
NZ600828A (en) Methods and compositions for diagnosis and prognosis of renal injury and renal failure
JP2006502416A5 (https=)
JP2007525427A5 (https=)
CA2522747A1 (en) Method of detecting native probnp with a monoclonal antibody binding to the amino acids 38-43
RU2010133157A (ru) Определение комплекса sflt-1:ангиогенный фактор
JP2003518138A5 (https=)
CA2949731A1 (en) New markers for the assessment of an increased risk for mortality
AU2009224113B2 (en) Biomarkers
JP2008538812A5 (https=)
CN103140498A (zh) 信号生物标志物
JP7428657B2 (ja) 標的物質の分離方法および定量方法
CN103698533A (zh) Apo-A1蛋白在制备肺癌早期筛查或诊断用血清标记物的用途
JP2006505245A (ja) 心臓血管疾患リスクの評価に有用なタンパク質および方法
Mötzing et al. Immunological Quantitation of the Glycation Site Lysine‐414 in Serum Albumin in Human Plasma Samples by Indirect ELISA Using Highly Specific Monoclonal Antibodies
JP2012504408A5 (https=)
Millar et al. Immunoradiometric assay for human serum amyloid P component
WO2007087013B1 (en) Functional immunoassay
US20190250172A1 (en) Prognosis of adverse outcomes by determination of midkine levels after cardiovascular stress