JP2005505757A5 - - Google Patents

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Publication number
JP2005505757A5
JP2005505757A5 JP2003528210A JP2003528210A JP2005505757A5 JP 2005505757 A5 JP2005505757 A5 JP 2005505757A5 JP 2003528210 A JP2003528210 A JP 2003528210A JP 2003528210 A JP2003528210 A JP 2003528210A JP 2005505757 A5 JP2005505757 A5 JP 2005505757A5
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JP
Japan
Prior art keywords
reagent
ctgf
sample
region
terminal fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Application number
JP2003528210A
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English (en)
Japanese (ja)
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JP2005505757A (ja
JP4226471B2 (ja
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Application filed filed Critical
Priority claimed from PCT/US2002/029500 external-priority patent/WO2003024308A2/en
Publication of JP2005505757A publication Critical patent/JP2005505757A/ja
Publication of JP2005505757A5 publication Critical patent/JP2005505757A5/ja
Application granted granted Critical
Publication of JP4226471B2 publication Critical patent/JP4226471B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2003528210A 2001-09-18 2002-09-18 結合組織増殖因子の分析方法 Expired - Fee Related JP4226471B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US32330501P 2001-09-18 2001-09-18
PCT/US2002/029500 WO2003024308A2 (en) 2001-09-18 2002-09-18 Methods of assaying connective tissue growth factor

Publications (3)

Publication Number Publication Date
JP2005505757A JP2005505757A (ja) 2005-02-24
JP2005505757A5 true JP2005505757A5 (enExample) 2006-01-05
JP4226471B2 JP4226471B2 (ja) 2009-02-18

Family

ID=23258613

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2003528210A Expired - Fee Related JP4226471B2 (ja) 2001-09-18 2002-09-18 結合組織増殖因子の分析方法

Country Status (6)

Country Link
US (2) US20030113816A1 (enExample)
EP (1) EP1434993B1 (enExample)
JP (1) JP4226471B2 (enExample)
CN (1) CN1589403B (enExample)
AU (1) AU2002326939A1 (enExample)
WO (1) WO2003024308A2 (enExample)

Families Citing this family (24)

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AU2002366641A1 (en) * 2001-12-11 2003-06-23 Fibrogen, Inc. Methods for inhibiting ocular processes
US20060074018A1 (en) * 2002-06-04 2006-04-06 Metabolex Inc Methods of diagnosing & treating diabetes and insulin resistance
US7405274B2 (en) 2003-06-04 2008-07-29 Fibrogen, Inc. Connective tissue growth factor antibodies
AU2005244154C1 (en) 2004-04-28 2010-07-01 Fibrogen, Inc. Treatments for pancreatic cancer
EP1740221A4 (en) * 2004-04-29 2009-01-07 Genzyme Corp METHOD AND COMPOSITIONS FOR TREATING POLYCYSTIC DISEASES
CN101120252A (zh) 2005-02-18 2008-02-06 儿童医疗中心有限公司 作为生物标记物用于上皮来源的癌症的诊断和预后的cyr61
WO2006122043A2 (en) * 2005-05-05 2006-11-16 Fibrogen, Inc. Diagnostic marker for diabetic vascular complications
EP2074429B1 (en) 2006-10-16 2012-04-04 Bayer Pharma Aktiengesellschaft Ctgf as a biomarker, therapeutic and diagnostic target
JP2008295328A (ja) * 2007-05-30 2008-12-11 Fujifilm Corp 卵巣癌の検出方法、及び抑制方法
JP5104622B2 (ja) * 2008-07-29 2012-12-19 Ｊｎｃ株式会社 磁性粒子を用いた測定対象物質の濃度測定法
CN108165548B (zh) * 2008-09-22 2022-10-14 菲奥医药公司 减小大小的自递送RNAi化合物
EP2221387A1 (en) 2009-02-19 2010-08-25 Université de la Méditerranée Fibrosis susceptibility gene and uses thereof
KR102453078B1 (ko) 2010-03-24 2022-10-11 피오 파마슈티칼스 코프. 진피 및 섬유증성 적응증에서의 ｒｎａ 간섭
CN103200945B (zh) 2010-03-24 2016-07-06 雷克西制药公司 眼部症候中的rna干扰
EP2558859B1 (en) * 2010-04-15 2017-09-27 Digital Sensing Limited Three dimensionsal microarrays
US20140134181A1 (en) 2010-11-05 2014-05-15 Kenneth E. Lipson Treatment Method For Lung Remodeling Diseases
US9102721B2 (en) 2011-01-21 2015-08-11 Fibrogen, Inc. Therapeutic method
DK2739748T3 (da) 2011-08-05 2019-06-24 Univ Aix Marseille Il22ra2-gen med fibrosefølsomhed og anvendelser deraf
JP5445885B2 (ja) * 2011-10-13 2014-03-19 特種東海製紙株式会社 電気化学素子用セパレータ及びその製造方法
WO2013148159A1 (en) * 2012-03-30 2013-10-03 Fibrogen Inc Therapeutic methods for peritoneal carcinomatosis
ES2718472T3 (es) 2012-05-03 2019-07-02 Fibrogen Inc Métodos para tratar fibrosis pulmonar idiopática
US9377473B2 (en) * 2013-03-15 2016-06-28 Harald Jueppner Immunoassays and methods of detecting and measuring intact fibroblast growth factor 23, and C-terminal and N-terminal fragments thereof
US9631013B2 (en) 2014-01-28 2017-04-25 Fibrogen, Inc. Therapeutic method for pancreatic cancer
CN109402127B (zh) * 2018-09-29 2021-12-10 复旦大学附属眼耳鼻喉科医院 一组与结缔组织生长因子特异性结合的高亲和力核酸适配体及其应用

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US4486530A (en) 1980-08-04 1984-12-04 Hybritech Incorporated Immunometric assays using monoclonal antibodies
US4376110A (en) 1980-08-04 1983-03-08 Hybritech, Incorporated Immunometric assays using monoclonal antibodies
US5530101A (en) 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
KR100272077B1 (ko) 1990-08-29 2000-11-15 젠팜인터내셔날,인코포레이티드 이종 항체를 생산할 수 있는 전이유전자를 가진 인간이외의 동물
US5545806A (en) 1990-08-29 1996-08-13 Genpharm International, Inc. Ransgenic non-human animals for producing heterologous antibodies
US5770209A (en) * 1991-08-30 1998-06-23 University Of South Florida Acceleration of wound healing using connective tissue growth factor
US5408040A (en) * 1991-08-30 1995-04-18 University Of South Florida Connective tissue growth factor(CTGF)
US5474796A (en) 1991-09-04 1995-12-12 Protogene Laboratories, Inc. Method and apparatus for conducting an array of chemical reactions on a support surface
US5565332A (en) 1991-09-23 1996-10-15 Medical Research Council Production of chimeric antibodies - a combinatorial approach
US5605662A (en) 1993-11-01 1997-02-25 Nanogen, Inc. Active programmable electronic devices for molecular biological analysis and diagnostics
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US5461854A (en) 1993-07-07 1995-10-31 Griffin, Jr.; Arthur T. Combustor cooling for gas turbine engines
US5916756A (en) * 1993-12-14 1999-06-29 University Of South Florida Assay of connective tissue growth factor for detection of cell proliferative disorders
US6015880A (en) 1994-03-16 2000-01-18 California Institute Of Technology Method and substrate for performing multiple sequential reactions on a matrix
US5807522A (en) 1994-06-17 1998-09-15 The Board Of Trustees Of The Leland Stanford Junior University Methods for fabricating microarrays of biological samples
US7026299B2 (en) * 1994-07-12 2006-04-11 Human Genome Sciences, Inc. Connective tissue growth factor-2
EP0854934A4 (en) * 1995-08-18 2000-09-06 Donald W Landry DETECTION OF ORGANIC COMPOUNDS BY REGULATION OF ANTIBODY CATALYZED REACTIONS
US5876730A (en) * 1997-08-07 1999-03-02 Childrens Hospital Research Foundation Heparin-binding growth factor (HBGF) polypeptides
WO1999033878A1 (en) * 1997-12-25 1999-07-08 Japan Tobacco Inc. Monoclonal antibody against connective tissue growth factor and medicinal uses thereof
ATE485834T1 (de) 1998-09-08 2010-11-15 Ford Henry Health System Verfahren zum nachweis von bindegewebswachstumsfaktor zur diagnose von nierkrankheiten
CN1332801A (zh) 1998-11-06 2002-01-23 法布罗根公司 结缔组织生长因子(ctgf)及应用方法
US7115390B1 (en) * 1998-12-14 2006-10-03 Fibrogen, Inc. Connective tissue growth factor fragments and methods and uses thereof
US6492129B1 (en) * 1998-12-14 2002-12-10 University Of Miami Fragments of connective tissue growth factor that induce extracellular matrix synthesis, collagen synthesis and/or myofibroblast differentiation
WO2001015729A1 (en) 1999-08-27 2001-03-08 Fibrogen, Inc. Connective tissue growth factor receptor, its agonists and antagonists, and their therapeutic and diagnostic uses

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