JP2005502339A5 - - Google Patents
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- Publication number
- JP2005502339A5 JP2005502339A5 JP2003521262A JP2003521262A JP2005502339A5 JP 2005502339 A5 JP2005502339 A5 JP 2005502339A5 JP 2003521262 A JP2003521262 A JP 2003521262A JP 2003521262 A JP2003521262 A JP 2003521262A JP 2005502339 A5 JP2005502339 A5 JP 2005502339A5
- Authority
- JP
- Japan
- Prior art keywords
- allergen
- cysteine
- seq
- recombinant
- derp1
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013566 allergen Substances 0.000 claims 8
- 230000035772 mutation Effects 0.000 claims 7
- XUJNEKJLAYXESH-UHFFFAOYSA-N cysteine Natural products SCC(N)C(O)=O XUJNEKJLAYXESH-UHFFFAOYSA-N 0.000 claims 6
- 235000018417 cysteine Nutrition 0.000 claims 6
- 230000001900 immune effect Effects 0.000 claims 5
- 239000000203 mixture Substances 0.000 claims 5
- 239000002671 adjuvant Substances 0.000 claims 4
- 150000007523 nucleic acids Chemical class 0.000 claims 4
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 claims 2
- 108091028043 Nucleic acid sequence Proteins 0.000 claims 2
- 102000007056 Recombinant Fusion Proteins Human genes 0.000 claims 2
- 108010008281 Recombinant Fusion Proteins Proteins 0.000 claims 2
- 239000003814 drug Substances 0.000 claims 2
- 108020004707 nucleic acids Proteins 0.000 claims 2
- 102000039446 nucleic acids Human genes 0.000 claims 2
- 108090000623 proteins and genes Proteins 0.000 claims 2
- 108700010070 Codon Usage Proteins 0.000 claims 1
- 101100243396 Dermatophagoides pteronyssinus DERP1 gene Proteins 0.000 claims 1
- 206010020751 Hypersensitivity Diseases 0.000 claims 1
- 108091034117 Oligonucleotide Proteins 0.000 claims 1
- 239000004698 Polyethylene Substances 0.000 claims 1
- 208000026935 allergic disease Diseases 0.000 claims 1
- 230000007815 allergy Effects 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 150000002148 esters Chemical class 0.000 claims 1
- 239000013604 expression vector Substances 0.000 claims 1
- 230000028993 immune response Effects 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 239000007764 o/w emulsion Substances 0.000 claims 1
- -1 polyethylene Polymers 0.000 claims 1
- 229920000573 polyethylene Polymers 0.000 claims 1
- 108091033319 polynucleotide Proteins 0.000 claims 1
- 102000040430 polynucleotide Human genes 0.000 claims 1
- 239000002157 polynucleotide Substances 0.000 claims 1
- 235000018102 proteins Nutrition 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 239000013598 vector Substances 0.000 claims 1
- 239000007762 w/o emulsion Substances 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB0120150.8A GB0120150D0 (en) | 2001-08-17 | 2001-08-17 | Novel compounds |
| PCT/EP2002/009122 WO2003016340A1 (en) | 2001-08-17 | 2002-08-15 | Derp1 and proderp1 allergen derivatives |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005502339A JP2005502339A (ja) | 2005-01-27 |
| JP2005502339A5 true JP2005502339A5 (enExample) | 2006-01-05 |
Family
ID=9920622
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003521262A Pending JP2005502339A (ja) | 2001-08-17 | 2002-08-15 | Ｄｅｒｐ１およびｐｒｏｄｅｒｐ１アレルゲン誘導体 |
Country Status (6)
| Country | Link |
|---|---|
| US (2) | US20040234538A1 (enExample) |
| EP (1) | EP1417226A1 (enExample) |
| JP (1) | JP2005502339A (enExample) |
| CA (1) | CA2457163A1 (enExample) |
| GB (1) | GB0120150D0 (enExample) |
| WO (1) | WO2003016340A1 (enExample) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2003300681A1 (en) * | 2002-10-02 | 2004-05-04 | Diamyd Medical Ab | Formulation of glutarmic acid decarboxylase (gad65) and serum albumin |
| GB0304424D0 (en) * | 2003-02-26 | 2003-04-02 | Glaxosmithkline Biolog Sa | Novel compounds |
| CA2523402A1 (en) * | 2003-04-25 | 2004-11-11 | Novozymes A/S | Group 1 mite polypeptide variants |
| WO2006026994A1 (en) * | 2004-09-09 | 2006-03-16 | Alk-Abelló A/S | Crystal structure of house dust mite allergen der p 1 |
| FR2889592B1 (fr) * | 2005-08-03 | 2008-09-12 | Inst Nat Agronomique Paris Gri | Procede pour tester l'aptitude d'une composition a provoquer une reaction allergique croisee avec un allergene derive de l'arachide |
| EP1835031A1 (en) * | 2006-03-14 | 2007-09-19 | Paul-Ehrlich-Institut Bundesamt für Sera und Impfstoffe | Use of a recombinant modified vaccinia virus Ankara (MVA) for the treatment of type I hypersensitivity in a living animal including humans |
| WO2008154350A2 (en) * | 2007-06-08 | 2008-12-18 | Alba Therapeutics Corporation | Use of tight junction agonists to suppress immune responses |
| NL2014882B1 (en) | 2015-05-29 | 2017-01-31 | Citeq B V | Allergy-specific immunotherapy compositions for use in the treatment of house-dust mite allergy. |
| GB201806819D0 (en) * | 2018-04-26 | 2018-06-13 | Univ Gent | Compositions for active immunotherapy |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5433948A (en) * | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
| US6849427B1 (en) * | 1993-03-12 | 2005-02-01 | Immulogic Pharmaceutical Corp. | Nucleic acids encoding a house dust mite allergen, Der p VII, and uses therefor |
| EP1043032A3 (en) * | 1994-07-29 | 2000-11-15 | Kenneth Houlbrook | Use of moisture and heat for de-naturing house dust mite (HDM) allergen |
| US5670356A (en) * | 1994-12-12 | 1997-09-23 | Promega Corporation | Modified luciferase |
| US5762943A (en) * | 1996-05-14 | 1998-06-09 | Ribi Immunochem Research, Inc. | Methods of treating type I hypersensitivity using monophosphoryl lipid A |
| GB9724531D0 (en) * | 1997-11-19 | 1998-01-21 | Smithkline Biolog | Novel compounds |
| US6455686B1 (en) * | 1998-04-17 | 2002-09-24 | Heska Corporation | Dermatophagoides nucleic acid molecules, proteins and uses thereof |
| WO2001029078A2 (en) * | 1999-10-15 | 2001-04-26 | Heska Corporation | Method for production and use of mite group 1 proteins |
| GB0014288D0 (en) * | 2000-06-10 | 2000-08-02 | Smithkline Beecham Biolog | Vaccine |
-
2001
- 2001-08-17 GB GBGB0120150.8A patent/GB0120150D0/en not_active Ceased
-
2002
- 2002-08-15 US US10/486,910 patent/US20040234538A1/en not_active Abandoned
- 2002-08-15 EP EP02767386A patent/EP1417226A1/en not_active Withdrawn
- 2002-08-15 WO PCT/EP2002/009122 patent/WO2003016340A1/en not_active Ceased
- 2002-08-15 CA CA002457163A patent/CA2457163A1/en not_active Abandoned
- 2002-08-15 JP JP2003521262A patent/JP2005502339A/ja active Pending
-
2007
- 2007-01-16 US US11/623,498 patent/US20070122423A1/en not_active Abandoned
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