JP2005501863A5 - - Google Patents
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- Publication number
- JP2005501863A5 JP2005501863A5 JP2003522566A JP2003522566A JP2005501863A5 JP 2005501863 A5 JP2005501863 A5 JP 2005501863A5 JP 2003522566 A JP2003522566 A JP 2003522566A JP 2003522566 A JP2003522566 A JP 2003522566A JP 2005501863 A5 JP2005501863 A5 JP 2005501863A5
- Authority
- JP
- Japan
- Prior art keywords
- acid
- delivery system
- mixture
- milk
- apoprotein
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- DTOSIQBPPRVQHS-PDBXOOCHSA-N (Z,Z,Z)-Octadeca-9,12,15-trienoic acid Natural products CC\C=C/C\C=C/C\C=C/CCCCCCCC(O)=O DTOSIQBPPRVQHS-PDBXOOCHSA-N 0.000 claims description 6
- YZXBAPSDXZZRGB-DOFZRALJSA-N arachidonic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O YZXBAPSDXZZRGB-DOFZRALJSA-N 0.000 claims description 6
- 235000021588 free fatty acids Nutrition 0.000 claims description 6
- SECPZKHBENQXJG-FPLPWBNLSA-N palmitoleic acid Chemical compound CCCCCC\C=C/CCCCCCCC(O)=O SECPZKHBENQXJG-FPLPWBNLSA-N 0.000 claims description 6
- WRIDQFICGBMAFQ-UHFFFAOYSA-N (E)-8-Octadecenoic acid Natural products CCCCCCCCCC=CCCCCCCC(O)=O WRIDQFICGBMAFQ-UHFFFAOYSA-N 0.000 claims description 3
- ULNRTPCFRBIMKL-GHVJWSGMSA-N (e)-2-tetracosenoic acid Chemical compound CCCCCCCCCCCCCCCCCCCCC\C=C\C(O)=O ULNRTPCFRBIMKL-GHVJWSGMSA-N 0.000 claims description 3
- LQJBNNIYVWPHFW-UHFFFAOYSA-N 20:1omega9c fatty acid Natural products CCCCCCCCCCC=CCCCCCCCC(O)=O LQJBNNIYVWPHFW-UHFFFAOYSA-N 0.000 claims description 3
- QSBYPNXLFMSGKH-UHFFFAOYSA-N 9-Heptadecensaeure Natural products CCCCCCCC=CCCCCCCCC(O)=O QSBYPNXLFMSGKH-UHFFFAOYSA-N 0.000 claims description 3
- 239000005642 Oleic acid Substances 0.000 claims description 3
- ZQPPMHVWECSIRJ-UHFFFAOYSA-N Oleic acid Natural products CCCCCCCCC=CCCCCCCCC(O)=O ZQPPMHVWECSIRJ-UHFFFAOYSA-N 0.000 claims description 3
- 235000021319 Palmitoleic acid Nutrition 0.000 claims description 3
- JAZBEHYOTPTENJ-JLNKQSITSA-N all-cis-5,8,11,14,17-icosapentaenoic acid Chemical compound CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O JAZBEHYOTPTENJ-JLNKQSITSA-N 0.000 claims description 3
- 235000020661 alpha-linolenic acid Nutrition 0.000 claims description 3
- 235000021342 arachidonic acid Nutrition 0.000 claims description 3
- 229940114079 arachidonic acid Drugs 0.000 claims description 3
- SECPZKHBENQXJG-UHFFFAOYSA-N cis-palmitoleic acid Natural products CCCCCCC=CCCCCCCCC(O)=O SECPZKHBENQXJG-UHFFFAOYSA-N 0.000 claims description 3
- GWHCXVQVJPWHRF-UHFFFAOYSA-N cis-tetracosenoic acid Natural products CCCCCCCCC=CCCCCCCCCCCCCCC(O)=O GWHCXVQVJPWHRF-UHFFFAOYSA-N 0.000 claims description 3
- JAZBEHYOTPTENJ-UHFFFAOYSA-N eicosapentaenoic acid Natural products CCC=CCC=CCC=CCC=CCC=CCCCC(O)=O JAZBEHYOTPTENJ-UHFFFAOYSA-N 0.000 claims description 3
- VZCCETWTMQHEPK-UHFFFAOYSA-N gamma-Linolensaeure Natural products CCCCCC=CCC=CCC=CCCCCC(O)=O VZCCETWTMQHEPK-UHFFFAOYSA-N 0.000 claims description 3
- VZCCETWTMQHEPK-QNEBEIHSSA-N gamma-linolenic acid Chemical compound CCCCC\C=C/C\C=C/C\C=C/CCCCC(O)=O VZCCETWTMQHEPK-QNEBEIHSSA-N 0.000 claims description 3
- 235000020664 gamma-linolenic acid Nutrition 0.000 claims description 3
- 229960002733 gamolenic acid Drugs 0.000 claims description 3
- QXJSBBXBKPUZAA-UHFFFAOYSA-N isooleic acid Natural products CCCCCCCC=CCCCCCCCCC(O)=O QXJSBBXBKPUZAA-UHFFFAOYSA-N 0.000 claims description 3
- 229960004488 linolenic acid Drugs 0.000 claims description 3
- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 claims description 3
- 239000000203 mixture Substances 0.000 claims 29
- 235000013336 milk Nutrition 0.000 claims 20
- 239000008267 milk Substances 0.000 claims 20
- 210000004080 milk Anatomy 0.000 claims 20
- 102000006410 Apoproteins Human genes 0.000 claims 13
- 108010083590 Apoproteins Proteins 0.000 claims 13
- 239000005862 Whey Substances 0.000 claims 6
- 102000007544 Whey Proteins Human genes 0.000 claims 6
- 108010046377 Whey Proteins Proteins 0.000 claims 6
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 claims 5
- 150000002148 esters Chemical class 0.000 claims 5
- 150000007524 organic acids Chemical class 0.000 claims 5
- 150000003839 salts Chemical class 0.000 claims 5
- FERIUCNNQQJTOY-UHFFFAOYSA-N Butyric acid Chemical compound CCCC(O)=O FERIUCNNQQJTOY-UHFFFAOYSA-N 0.000 claims 4
- WNLRTRBMVRJNCN-UHFFFAOYSA-N adipic acid Chemical compound OC(=O)CCCCC(O)=O WNLRTRBMVRJNCN-UHFFFAOYSA-N 0.000 claims 4
- GHVNFZFCNZKVNT-UHFFFAOYSA-N decanoic acid Chemical compound CCCCCCCCCC(O)=O GHVNFZFCNZKVNT-UHFFFAOYSA-N 0.000 claims 4
- POULHZVOKOAJMA-UHFFFAOYSA-N dodecanoic acid Chemical compound CCCCCCCCCCCC(O)=O POULHZVOKOAJMA-UHFFFAOYSA-N 0.000 claims 4
- IPCSVZSSVZVIGE-UHFFFAOYSA-N hexadecanoic acid Chemical compound CCCCCCCCCCCCCCCC(O)=O IPCSVZSSVZVIGE-UHFFFAOYSA-N 0.000 claims 4
- FUZZWVXGSFPDMH-UHFFFAOYSA-N hexanoic acid Chemical compound CCCCCC(O)=O FUZZWVXGSFPDMH-UHFFFAOYSA-N 0.000 claims 4
- KQNPFQTWMSNSAP-UHFFFAOYSA-N isobutyric acid Chemical compound CC(C)C(O)=O KQNPFQTWMSNSAP-UHFFFAOYSA-N 0.000 claims 4
- WWZKQHOCKIZLMA-UHFFFAOYSA-N octanoic acid Chemical compound CCCCCCCC(O)=O WWZKQHOCKIZLMA-UHFFFAOYSA-N 0.000 claims 4
- 102000004190 Enzymes Human genes 0.000 claims 3
- 108090000790 Enzymes Proteins 0.000 claims 3
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 claims 3
- OFOBLEOULBTSOW-UHFFFAOYSA-N Propanedioic acid Natural products OC(=O)CC(O)=O OFOBLEOULBTSOW-UHFFFAOYSA-N 0.000 claims 3
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 claims 3
- KRKNYBCHXYNGOX-UHFFFAOYSA-N citric acid Chemical compound OC(=O)CC(O)(C(O)=O)CC(O)=O KRKNYBCHXYNGOX-UHFFFAOYSA-N 0.000 claims 3
- 230000001419 dependent effect Effects 0.000 claims 3
- OYHQOLUKZRVURQ-NTGFUMLPSA-N (9Z,12Z)-9,10,12,13-tetratritiooctadeca-9,12-dienoic acid Chemical compound C(CCCCCCC\C(=C(/C\C(=C(/CCCCC)\[3H])\[3H])\[3H])\[3H])(=O)O OYHQOLUKZRVURQ-NTGFUMLPSA-N 0.000 claims 2
- NIXOWILDQLNWCW-UHFFFAOYSA-N Acrylic acid Chemical compound OC(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-N 0.000 claims 2
- 102000007592 Apolipoproteins Human genes 0.000 claims 2
- 108010071619 Apolipoproteins Proteins 0.000 claims 2
- 239000005632 Capric acid (CAS 334-48-5) Substances 0.000 claims 2
- 239000005635 Caprylic acid (CAS 124-07-2) Substances 0.000 claims 2
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 claims 2
- AEMRFAOFKBGASW-UHFFFAOYSA-N Glycolic acid Chemical compound OCC(O)=O AEMRFAOFKBGASW-UHFFFAOYSA-N 0.000 claims 2
- 102000004407 Lactalbumin Human genes 0.000 claims 2
- 108090000942 Lactalbumin Proteins 0.000 claims 2
- 102000008192 Lactoglobulins Human genes 0.000 claims 2
- 108010060630 Lactoglobulins Proteins 0.000 claims 2
- 239000005639 Lauric acid Substances 0.000 claims 2
- 102000004882 Lipase Human genes 0.000 claims 2
- 108090001060 Lipase Proteins 0.000 claims 2
- 239000004367 Lipase Substances 0.000 claims 2
- 241001465754 Metazoa Species 0.000 claims 2
- 235000021314 Palmitic acid Nutrition 0.000 claims 2
- 235000021355 Stearic acid Nutrition 0.000 claims 2
- KDYFGRWQOYBRFD-UHFFFAOYSA-N Succinic acid Natural products OC(=O)CCC(O)=O KDYFGRWQOYBRFD-UHFFFAOYSA-N 0.000 claims 2
- 239000001361 adipic acid Substances 0.000 claims 2
- 235000011037 adipic acid Nutrition 0.000 claims 2
- KDYFGRWQOYBRFD-NUQCWPJISA-N butanedioic acid Chemical compound O[14C](=O)CC[14C](O)=O KDYFGRWQOYBRFD-NUQCWPJISA-N 0.000 claims 2
- 235000014113 dietary fatty acids Nutrition 0.000 claims 2
- 235000019197 fats Nutrition 0.000 claims 2
- 229930195729 fatty acid Natural products 0.000 claims 2
- 239000000194 fatty acid Substances 0.000 claims 2
- 150000004665 fatty acids Chemical class 0.000 claims 2
- 150000002430 hydrocarbons Chemical group 0.000 claims 2
- 230000003301 hydrolyzing effect Effects 0.000 claims 2
- ROBFUDYVXSDBQM-UHFFFAOYSA-N hydroxymalonic acid Chemical compound OC(=O)C(O)C(O)=O ROBFUDYVXSDBQM-UHFFFAOYSA-N 0.000 claims 2
- JVTAAEKCZFNVCJ-UHFFFAOYSA-N lactic acid Chemical compound CC(O)C(O)=O JVTAAEKCZFNVCJ-UHFFFAOYSA-N 0.000 claims 2
- 235000019421 lipase Nutrition 0.000 claims 2
- 239000012528 membrane Substances 0.000 claims 2
- WQEPLUUGTLDZJY-UHFFFAOYSA-N n-Pentadecanoic acid Natural products CCCCCCCCCCCCCCC(O)=O WQEPLUUGTLDZJY-UHFFFAOYSA-N 0.000 claims 2
- QIQXTHQIDYTFRH-UHFFFAOYSA-N octadecanoic acid Chemical compound CCCCCCCCCCCCCCCCCC(O)=O QIQXTHQIDYTFRH-UHFFFAOYSA-N 0.000 claims 2
- OQCDKBAXFALNLD-UHFFFAOYSA-N octadecanoic acid Natural products CCCCCCCC(C)CCCCCCCCC(O)=O OQCDKBAXFALNLD-UHFFFAOYSA-N 0.000 claims 2
- 229960002446 octanoic acid Drugs 0.000 claims 2
- 229960002969 oleic acid Drugs 0.000 claims 2
- 235000021313 oleic acid Nutrition 0.000 claims 2
- 244000052769 pathogen Species 0.000 claims 2
- 230000002265 prevention Effects 0.000 claims 2
- 230000003449 preventive effect Effects 0.000 claims 2
- 239000008117 stearic acid Substances 0.000 claims 2
- TUNFSRHWOTWDNC-HKGQFRNVSA-N tetradecanoic acid Chemical compound CCCCCCCCCCCCC[14C](O)=O TUNFSRHWOTWDNC-HKGQFRNVSA-N 0.000 claims 2
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 claims 2
- 235000021122 unsaturated fatty acids Nutrition 0.000 claims 2
- 150000004670 unsaturated fatty acids Chemical class 0.000 claims 2
- 235000021241 α-lactalbumin Nutrition 0.000 claims 2
- GVJHHUAWPYXKBD-IEOSBIPESA-N α-tocopherol Chemical compound OC1=C(C)C(C)=C2O[C@@](CCC[C@H](C)CCC[C@H](C)CCCC(C)C)(C)CCC2=C1C GVJHHUAWPYXKBD-IEOSBIPESA-N 0.000 claims 2
- BJEPYKJPYRNKOW-REOHCLBHSA-N (S)-malic acid Chemical compound OC(=O)[C@@H](O)CC(O)=O BJEPYKJPYRNKOW-REOHCLBHSA-N 0.000 claims 1
- RBNPOMFGQQGHHO-UHFFFAOYSA-N -2,3-Dihydroxypropanoic acid Natural products OCC(O)C(O)=O RBNPOMFGQQGHHO-UHFFFAOYSA-N 0.000 claims 1
- RTBFRGCFXZNCOE-UHFFFAOYSA-N 1-methylsulfonylpiperidin-4-one Chemical compound CS(=O)(=O)N1CCC(=O)CC1 RTBFRGCFXZNCOE-UHFFFAOYSA-N 0.000 claims 1
- 206010007134 Candida infections Diseases 0.000 claims 1
- 208000035473 Communicable disease Diseases 0.000 claims 1
- RBNPOMFGQQGHHO-UWTATZPHSA-N D-glyceric acid Chemical compound OC[C@@H](O)C(O)=O RBNPOMFGQQGHHO-UWTATZPHSA-N 0.000 claims 1
- FEWJPZIEWOKRBE-JCYAYHJZSA-N Dextrotartaric acid Chemical compound OC(=O)[C@H](O)[C@@H](O)C(O)=O FEWJPZIEWOKRBE-JCYAYHJZSA-N 0.000 claims 1
- 208000001860 Eye Infections Diseases 0.000 claims 1
- 206010022678 Intestinal infections Diseases 0.000 claims 1
- 102000004895 Lipoproteins Human genes 0.000 claims 1
- 108090001030 Lipoproteins Proteins 0.000 claims 1
- 208000025157 Oral disease Diseases 0.000 claims 1
- FEWJPZIEWOKRBE-UHFFFAOYSA-N Tartaric acid Natural products [H+].[H+].[O-]C(=O)C(O)C(O)C([O-])=O FEWJPZIEWOKRBE-UHFFFAOYSA-N 0.000 claims 1
- 229940087168 alpha tocopherol Drugs 0.000 claims 1
- BJEPYKJPYRNKOW-UHFFFAOYSA-N alpha-hydroxysuccinic acid Natural products OC(=O)C(O)CC(O)=O BJEPYKJPYRNKOW-UHFFFAOYSA-N 0.000 claims 1
- JFCQEDHGNNZCLN-UHFFFAOYSA-N anhydrous glutaric acid Natural products OC(=O)CCCC(O)=O JFCQEDHGNNZCLN-UHFFFAOYSA-N 0.000 claims 1
- 239000003963 antioxidant agent Substances 0.000 claims 1
- 230000003078 antioxidant effect Effects 0.000 claims 1
- 235000006708 antioxidants Nutrition 0.000 claims 1
- 235000013361 beverage Nutrition 0.000 claims 1
- 230000003115 biocidal effect Effects 0.000 claims 1
- 230000005540 biological transmission Effects 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 229940112822 chewing gum Drugs 0.000 claims 1
- 235000015218 chewing gum Nutrition 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 239000002537 cosmetic Substances 0.000 claims 1
- 239000006071 cream Substances 0.000 claims 1
- LDHQCZJRKDOVOX-NSCUHMNNSA-N crotonic acid Chemical compound C\C=C\C(O)=O LDHQCZJRKDOVOX-NSCUHMNNSA-N 0.000 claims 1
- 239000000551 dentifrice Substances 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000003937 drug carrier Substances 0.000 claims 1
- 210000001508 eye Anatomy 0.000 claims 1
- 239000003889 eye drop Substances 0.000 claims 1
- 229940012356 eye drops Drugs 0.000 claims 1
- 208000011323 eye infectious disease Diseases 0.000 claims 1
- 235000013305 food Nutrition 0.000 claims 1
- 238000009472 formulation Methods 0.000 claims 1
- 239000001530 fumaric acid Substances 0.000 claims 1
- 210000004392 genitalia Anatomy 0.000 claims 1
- 235000020251 goat milk Nutrition 0.000 claims 1
- 208000015181 infectious disease Diseases 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
- 239000007924 injection Substances 0.000 claims 1
- 238000002347 injection Methods 0.000 claims 1
- 210000000936 intestine Anatomy 0.000 claims 1
- 239000004310 lactic acid Substances 0.000 claims 1
- 235000014655 lactic acid Nutrition 0.000 claims 1
- 239000007788 liquid Substances 0.000 claims 1
- VZCYOOQTPOCHFL-UPHRSURJSA-N maleic acid Chemical compound OC(=O)\C=C/C(O)=O VZCYOOQTPOCHFL-UPHRSURJSA-N 0.000 claims 1
- 239000011976 maleic acid Substances 0.000 claims 1
- 239000001630 malic acid Substances 0.000 claims 1
- 235000011090 malic acid Nutrition 0.000 claims 1
- 238000004519 manufacturing process Methods 0.000 claims 1
- 244000005700 microbiome Species 0.000 claims 1
- 210000000214 mouth Anatomy 0.000 claims 1
- 208000030194 mouth disease Diseases 0.000 claims 1
- 210000001331 nose Anatomy 0.000 claims 1
- 235000006408 oxalic acid Nutrition 0.000 claims 1
- 229920006395 saturated elastomer Polymers 0.000 claims 1
- 206010040872 skin infection Diseases 0.000 claims 1
- 239000000243 solution Substances 0.000 claims 1
- 239000007921 spray Substances 0.000 claims 1
- 230000009885 systemic effect Effects 0.000 claims 1
- 239000011975 tartaric acid Substances 0.000 claims 1
- 235000002906 tartaric acid Nutrition 0.000 claims 1
- 229960000984 tocofersolan Drugs 0.000 claims 1
- 239000000606 toothpaste Substances 0.000 claims 1
- 229940034610 toothpaste Drugs 0.000 claims 1
- 229940100615 topical ointment Drugs 0.000 claims 1
- 239000002076 α-tocopherol Substances 0.000 claims 1
- 235000004835 α-tocopherol Nutrition 0.000 claims 1
- OYHQOLUKZRVURQ-HZJYTTRNSA-N Linoleic acid Chemical compound CCCCC\C=C/C\C=C/CCCCCCCC(O)=O OYHQOLUKZRVURQ-HZJYTTRNSA-N 0.000 description 1
- 210000001072 colon Anatomy 0.000 description 1
- 229960005135 eicosapentaenoic acid Drugs 0.000 description 1
- 235000020673 eicosapentaenoic acid Nutrition 0.000 description 1
- 125000001183 hydrocarbyl group Chemical group 0.000 description 1
- 235000020778 linoleic acid Nutrition 0.000 description 1
- OYHQOLUKZRVURQ-IXWMQOLASA-N linoleic acid Natural products CCCCC\C=C/C\C=C\CCCCCCCC(O)=O OYHQOLUKZRVURQ-IXWMQOLASA-N 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| IES20010780 | 2001-08-23 | ||
| PCT/IE2002/000121 WO2003018049A2 (en) | 2001-08-23 | 2002-08-20 | Use of milk serum apoproteins in the prophylaxis or treatment of microbial or viral infection |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005501863A JP2005501863A (ja) | 2005-01-20 |
| JP2005501863A5 true JP2005501863A5 (enExample) | 2006-01-05 |
| JP4532900B2 JP4532900B2 (ja) | 2010-08-25 |
Family
ID=11042830
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003522566A Expired - Fee Related JP4532900B2 (ja) | 2001-08-23 | 2002-08-20 | 細菌またはウイルス感染症の予防または治療における乳清アポタンパク質の使用 |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US7687074B2 (enExample) |
| EP (1) | EP1427436B1 (enExample) |
| JP (1) | JP4532900B2 (enExample) |
| KR (1) | KR100907959B1 (enExample) |
| CN (1) | CN1578670B (enExample) |
| AT (1) | ATE399562T1 (enExample) |
| AU (1) | AU2002356112B2 (enExample) |
| CA (1) | CA2458146C (enExample) |
| DE (1) | DE60227389D1 (enExample) |
| DK (1) | DK1427436T3 (enExample) |
| ES (1) | ES2309228T3 (enExample) |
| NZ (1) | NZ531639A (enExample) |
| PT (1) | PT1427436E (enExample) |
| RU (1) | RU2305547C2 (enExample) |
| WO (1) | WO2003018049A2 (enExample) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2863168A1 (fr) * | 2003-12-04 | 2005-06-10 | Centre Nat Rech Scient | Utilisation d'inducteurs de la voie de degradation de la gamma-butyrolactone pour inactiver le signal n-acy homoserine lactone. |
| CN101043884A (zh) * | 2004-07-01 | 2007-09-26 | 谢彭斯眼科研究公司 | 用于治疗眼部疾病和病症的组合物和方法 |
| EP1926834A4 (en) * | 2005-09-20 | 2009-04-22 | Prolacta Bioscience Inc | METHOD FOR ANALYZING MILK |
| EP2815754B1 (en) * | 2005-11-18 | 2016-06-08 | Glanbia Nutritionals (Ireland) Limited | Composition for treating biofilm-based infections |
| JP5017531B2 (ja) * | 2006-09-11 | 2012-09-05 | 株式会社アップウェル | 口内清浄剤 |
| JP2011505415A (ja) * | 2007-12-04 | 2011-02-24 | ウエストゲート・バイオロジカル・リミテッド | 遊離脂肪酸のブレンド及びその使用 |
| JP2009190994A (ja) * | 2008-02-13 | 2009-08-27 | Kitasato Institute | 抗インフルエンザウイルス剤、及びその有効成分の製造方法 |
| US20110098358A1 (en) * | 2008-06-11 | 2011-04-28 | Ricom Corporation | Human beta3 adrenergic receptor ligand, and food or pharmaceutical product containing the same |
| US20090311236A1 (en) * | 2008-06-11 | 2009-12-17 | Immune @Work, Inc. | Therapeutic Peptide Compositions And Methods Of Making And Using Same |
| US8808345B2 (en) * | 2008-12-31 | 2014-08-19 | Medtronic Ardian Luxembourg S.A.R.L. | Handle assemblies for intravascular treatment devices and associated systems and methods |
| WO2010082587A1 (ja) * | 2009-01-13 | 2010-07-22 | 株式会社大気倶楽部 | 空中懸濁物吸着剤 |
| KR101119538B1 (ko) * | 2009-06-10 | 2012-02-22 | 장선호 | 시알릭산-함유 유청 단백질을 유효성분으로 함유하는 인플루엔자 바이러스 감염증의 예방 및 치료용 조성물 |
| PL2501375T3 (pl) * | 2009-11-17 | 2017-12-29 | Folan | Kompozycje przeciwdrobnoustrojowe zawierające wolne kwasy tłuszczowe |
| UY33548A (es) * | 2010-08-06 | 2012-02-29 | Eurand Pharmaceuticals Inc | Formula nutricional predigerida |
| KR101355018B1 (ko) * | 2010-12-13 | 2014-01-24 | 노부오 구보 | 시알릭산-함유 유청 단백질을 유효성분으로 함유하는 인플루엔자 바이러스 감염증의 예방용 동물사료 첨가제 및 이를 포함하는 동물사료용 조성물 |
| RU2494726C2 (ru) * | 2011-04-11 | 2013-10-10 | Общество с Ограниченной Ответственностью "Производственная Торговая Компания "Лактив" | Способ профилактики и лечения грибковой инфекции у больных с голосовыми протезами |
| EP3150257A1 (en) * | 2015-09-30 | 2017-04-05 | Buga, Doris | A method for producing a composition for strengthening the immune system |
| CA3026402A1 (en) | 2017-12-05 | 2019-06-05 | James F. Kane | Water-soluble cannabinoids and methods of making same |
| US11298379B2 (en) * | 2020-04-16 | 2022-04-12 | James F. Kane | Compositions comprising milk fat globules and methods of making same |
| CN113855787A (zh) * | 2020-06-30 | 2021-12-31 | 北京大学 | 乳清蛋白作为冠状病毒广谱抑制剂的用途 |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2796378A (en) * | 1954-04-09 | 1957-06-18 | Jr Edgar A Ferguson | Methionine free reaction product of a water-soluble copper salt and lactalbumin hydrolysate as fungicide |
| GB1050756A (enExample) * | 1964-09-10 | 1900-01-01 | ||
| US4397927A (en) * | 1982-03-25 | 1983-08-09 | Brog Roy A | Imitation milk compositions and aqueous dispersions prepared therefrom |
| EP0210204B1 (de) | 1985-01-18 | 1988-12-07 | Kailash Kumar Dr. Prof. Gauri | Proteinhydrolysate, verfahren zu ihrer herstellung und arzneimittel, die diese hydrolysate enthalten |
| JPS62249931A (ja) | 1986-04-21 | 1987-10-30 | Morinaga Milk Ind Co Ltd | 抗菌性組成物 |
| JPH085798B2 (ja) * | 1987-02-02 | 1996-01-24 | 紀夫 多田 | 抗菌剤 |
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| CA2094570A1 (en) * | 1992-05-27 | 1993-11-28 | Jerome F. Trumbetas | Enzymatic protein process and product |
| EP0665721A1 (en) | 1992-10-30 | 1995-08-09 | Cancer Research Fund Of Contra Costa | Anti-diarrheic product and method of treating rotavirus-associated infection |
| US5785984A (en) * | 1993-02-05 | 1998-07-28 | Kao Corporation | Taste-modifying method and bitterness-decreasing method |
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| EP0776214B1 (en) * | 1994-08-16 | 1999-07-28 | Hemant Sabharwal | Antibacterial composition containing multimeric alpha-lactalbumin |
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| KR100530508B1 (ko) * | 1997-01-09 | 2005-11-23 | 모리나가 뉴교 가부시키가이샤 | 락토페린 정제 |
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| NZ509101A (en) * | 1998-06-26 | 2003-07-25 | N | Pharmaceutical preparations for use in combatting or preventing surface infections caused by microorganisms |
| JP2000119257A (ja) * | 1998-08-14 | 2000-04-25 | Nippon Nohyaku Co Ltd | ピリダジノン誘導体 |
| GB9903584D0 (en) | 1999-02-18 | 1999-04-07 | Univ Leeds | Modified calycins |
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| US20030165606A1 (en) | 2001-07-18 | 2003-09-04 | Lasekan John B. | Anti-regurgitation formula and uses thereof |
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-
2002
- 2002-08-20 RU RU2004108040/13A patent/RU2305547C2/ru not_active IP Right Cessation
- 2002-08-20 PT PT02796345T patent/PT1427436E/pt unknown
- 2002-08-20 JP JP2003522566A patent/JP4532900B2/ja not_active Expired - Fee Related
- 2002-08-20 AT AT02796345T patent/ATE399562T1/de active
- 2002-08-20 US US10/487,616 patent/US7687074B2/en not_active Expired - Lifetime
- 2002-08-20 DE DE60227389T patent/DE60227389D1/de not_active Expired - Lifetime
- 2002-08-20 CA CA2458146A patent/CA2458146C/en not_active Expired - Fee Related
- 2002-08-20 AU AU2002356112A patent/AU2002356112B2/en not_active Ceased
- 2002-08-20 CN CN028210786A patent/CN1578670B/zh not_active Expired - Fee Related
- 2002-08-20 WO PCT/IE2002/000121 patent/WO2003018049A2/en not_active Ceased
- 2002-08-20 EP EP02796345A patent/EP1427436B1/en not_active Expired - Lifetime
- 2002-08-20 ES ES02796345T patent/ES2309228T3/es not_active Expired - Lifetime
- 2002-08-20 DK DK02796345T patent/DK1427436T3/da active
- 2002-08-20 KR KR1020047002518A patent/KR100907959B1/ko not_active Expired - Fee Related
- 2002-08-20 NZ NZ531639A patent/NZ531639A/en not_active IP Right Cessation
-
2010
- 2010-01-30 US US12/657,884 patent/US7972629B2/en not_active Expired - Fee Related
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