JP2005342154A5 - - Google Patents
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- Publication number
- JP2005342154A5 JP2005342154A5 JP2004164367A JP2004164367A JP2005342154A5 JP 2005342154 A5 JP2005342154 A5 JP 2005342154A5 JP 2004164367 A JP2004164367 A JP 2004164367A JP 2004164367 A JP2004164367 A JP 2004164367A JP 2005342154 A5 JP2005342154 A5 JP 2005342154A5
- Authority
- JP
- Japan
- Prior art keywords
- layer
- edible
- intermediate product
- coating layer
- film
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000010410 layer Substances 0.000 description 20
- 239000013067 intermediate product Substances 0.000 description 8
- 239000011247 coating layer Substances 0.000 description 6
- 239000003814 drug Substances 0.000 description 5
- 229920002799 BoPET Polymers 0.000 description 4
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 4
- 238000002788 crimping Methods 0.000 description 4
- 229940079593 drug Drugs 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 238000002360 preparation method Methods 0.000 description 3
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- RMRJXGBAOAMLHD-IHFGGWKQSA-N buprenorphine Chemical compound C([C@]12[C@H]3OC=4C(O)=CC=C(C2=4)C[C@@H]2[C@]11CC[C@]3([C@H](C1)[C@](C)(O)C(C)(C)C)OC)CN2CC1CC1 RMRJXGBAOAMLHD-IHFGGWKQSA-N 0.000 description 2
- 229960001736 buprenorphine Drugs 0.000 description 2
- 230000001427 coherent effect Effects 0.000 description 2
- 239000001866 hydroxypropyl methyl cellulose Substances 0.000 description 2
- 229920003088 hydroxypropyl methyl cellulose Polymers 0.000 description 2
- UFVKGYZPFZQRLF-UHFFFAOYSA-N hydroxypropyl methyl cellulose Chemical compound OC1C(O)C(OC)OC(CO)C1OC1C(O)C(O)C(OC2C(C(O)C(OC3C(C(O)C(O)C(CO)O3)O)C(CO)O2)O)C(CO)O1 UFVKGYZPFZQRLF-UHFFFAOYSA-N 0.000 description 2
- 235000010979 hydroxypropyl methyl cellulose Nutrition 0.000 description 2
- 238000000034 method Methods 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 238000003825 pressing Methods 0.000 description 2
- 239000011347 resin Substances 0.000 description 2
- 229920005989 resin Polymers 0.000 description 2
- 239000002904 solvent Substances 0.000 description 2
- 239000007858 starting material Substances 0.000 description 2
- 238000003756 stirring Methods 0.000 description 2
- 239000002344 surface layer Substances 0.000 description 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 2
- LYCAIKOWRPUZTN-UHFFFAOYSA-N Ethylene glycol Chemical compound OCCO LYCAIKOWRPUZTN-UHFFFAOYSA-N 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- GWEVSGVZZGPLCZ-UHFFFAOYSA-N Titan oxide Chemical compound O=[Ti]=O GWEVSGVZZGPLCZ-UHFFFAOYSA-N 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- 230000000052 comparative effect Effects 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- XUFQPHANEAPEMJ-UHFFFAOYSA-N famotidine Chemical compound NC(N)=NC1=NC(CSCCC(N)=NS(N)(=O)=O)=CS1 XUFQPHANEAPEMJ-UHFFFAOYSA-N 0.000 description 1
- 229960001596 famotidine Drugs 0.000 description 1
- 239000011888 foil Substances 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 239000000845 maltitol Substances 0.000 description 1
- VQHSOMBJVWLPSR-WUJBLJFYSA-N maltitol Chemical compound OC[C@H](O)[C@@H](O)[C@@H]([C@H](O)CO)O[C@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O VQHSOMBJVWLPSR-WUJBLJFYSA-N 0.000 description 1
- 229940035436 maltitol Drugs 0.000 description 1
- 235000010449 maltitol Nutrition 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 239000012046 mixed solvent Substances 0.000 description 1
- 210000002200 mouth mucosa Anatomy 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000004080 punching Methods 0.000 description 1
- 230000003381 solubilizing effect Effects 0.000 description 1
- 239000000725 suspension Substances 0.000 description 1
- OGIDPMRJRNCKJF-UHFFFAOYSA-N titanium oxide Inorganic materials [Ti]=O OGIDPMRJRNCKJF-UHFFFAOYSA-N 0.000 description 1
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004164367A JP4547994B2 (ja) | 2004-06-02 | 2004-06-02 | 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法および塊状物質含有積層フィルム状の可食性口腔内投与剤 |
| EP05743754.3A EP1752127B1 (en) | 2004-06-02 | 2005-05-25 | Process for producing edible oral administration preparation of aggregated substance-containing laminated film, and edible oral administration preparation of aggregated substance-containing laminated film |
| US11/578,427 US8357415B2 (en) | 2004-06-02 | 2005-05-25 | Method for producing orally administrable edible agent of aggregated subtance-containing laminate film form and orally administrable edible agent of aggregated substance-containing laminate film form |
| PCT/JP2005/009535 WO2005117803A1 (ja) | 2004-06-02 | 2005-05-25 | 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法および塊状物質含有積層フィルム状の可食性口腔内投与剤 |
| US13/666,227 US20130064874A1 (en) | 2004-06-02 | 2012-11-01 | Method for producing orally administrable edible agent of aggregated substance-containing laminate film form and orally administrable edible agent of aggregated substance-containing laminate film form |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004164367A JP4547994B2 (ja) | 2004-06-02 | 2004-06-02 | 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法および塊状物質含有積層フィルム状の可食性口腔内投与剤 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2010121143A Division JP4952823B2 (ja) | 2010-05-27 | 2010-05-27 | 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005342154A JP2005342154A (ja) | 2005-12-15 |
| JP2005342154A5 true JP2005342154A5 (OSRAM) | 2006-11-09 |
| JP4547994B2 JP4547994B2 (ja) | 2010-09-22 |
Family
ID=35462705
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004164367A Expired - Lifetime JP4547994B2 (ja) | 2004-06-02 | 2004-06-02 | 塊状物質含有積層フィルム状の可食性口腔内投与剤の製造方法および塊状物質含有積層フィルム状の可食性口腔内投与剤 |
Country Status (4)
| Country | Link |
|---|---|
| US (2) | US8357415B2 (OSRAM) |
| EP (1) | EP1752127B1 (OSRAM) |
| JP (1) | JP4547994B2 (OSRAM) |
| WO (1) | WO2005117803A1 (OSRAM) |
Families Citing this family (34)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP5014712B2 (ja) * | 2006-09-06 | 2012-08-29 | ライオン株式会社 | 口腔内溶解フィルム |
| CA2689594A1 (en) * | 2007-06-07 | 2008-12-11 | Sato Pharmaceutical Co., Ltd. | Film preparation with rapidly dissolving property and flexibility |
| CN101883559B (zh) * | 2007-12-06 | 2011-12-28 | 琳得科株式会社 | 可食性薄膜 |
| EP2293779A1 (en) * | 2008-04-24 | 2011-03-16 | Evestra, Inc. | Oral contraceptive dosage forms comprising a progestogen dispersed in an enteric polymer and further comprising an estrogen |
| CN101455617B (zh) * | 2008-12-26 | 2011-11-16 | 天津大学 | 中药巴布剂横向供料药膜成型装置 |
| WO2010086989A1 (ja) * | 2009-01-29 | 2010-08-05 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| JP5674480B2 (ja) * | 2009-01-29 | 2015-02-25 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| EP2238976B1 (en) * | 2009-04-03 | 2012-06-27 | Hexal AG | Oral films comprising 7-[4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy]-3,4-dihydro- 1H-quinolin-2-one base or salts or hydrates thereof |
| JP5588688B2 (ja) * | 2010-01-28 | 2014-09-10 | 日東電工株式会社 | フィルム状製剤 |
| KR20130029758A (ko) * | 2010-03-03 | 2013-03-25 | 코와 가부시키가이샤 | 불쾌한 맛을 갖는 약물을 함유하는 필름 제제 |
| JP4620171B1 (ja) * | 2010-03-19 | 2011-01-26 | 株式会社ツキオカ | 可食フィルム |
| JP5751868B2 (ja) | 2010-03-30 | 2015-07-22 | 日東電工株式会社 | フィルム状製剤及びその製造方法 |
| WO2012108738A2 (ko) | 2011-02-11 | 2012-08-16 | 주식회사 씨티씨바이오 | 실데나필 유리염기 함유 필름 제제 및 이의 제조 방법 |
| JP5841433B2 (ja) | 2012-01-11 | 2016-01-13 | 日東電工株式会社 | 口腔内フィルム状基剤及び製剤 |
| WO2013119605A1 (en) * | 2012-02-07 | 2013-08-15 | University Of Pittsburgh - Of The Commonwealth System Of Higher Education | Promoting sleep using at1 receptor blockers |
| TWI594765B (zh) * | 2012-04-30 | 2017-08-11 | 大塚製藥股份有限公司 | 口服調製劑 |
| JP5952646B2 (ja) * | 2012-06-07 | 2016-07-13 | 救急薬品工業株式会社 | 口腔内溶解型フィルム製剤 |
| EP2732813A1 (en) * | 2012-11-14 | 2014-05-21 | Hexal AG | Orodispersible film compositions |
| US20140187406A1 (en) | 2012-12-29 | 2014-07-03 | Unicharm Corporation | Method of producing cleaning member |
| US20140182767A1 (en) | 2012-12-29 | 2014-07-03 | Unicharm Corporation | Method of producing cleaning member |
| US10098516B2 (en) | 2012-12-29 | 2018-10-16 | Unicharm Corporation | Method for producing cleaning member, and system for producing cleaning member |
| JP6047401B2 (ja) | 2012-12-29 | 2016-12-21 | ユニ・チャーム株式会社 | 開繊された繊維束の製造方法、清掃部材の製造方法、繊維束の開繊装置、及び清掃部材の製造システム |
| JP6047400B2 (ja) | 2012-12-29 | 2016-12-21 | ユニ・チャーム株式会社 | 清掃部材を製造する方法及び装置 |
| JP6073128B2 (ja) | 2012-12-29 | 2017-02-01 | ユニ・チャーム株式会社 | 切断装置及び切断装置を用いた清掃部材の製造方法 |
| JP6057707B2 (ja) | 2012-12-29 | 2017-01-11 | ユニ・チャーム株式会社 | 開繊された繊維束の製造方法、清掃部材の製造方法、繊維束の開繊装置、及び清掃部材の製造システム |
| JP6080550B2 (ja) * | 2012-12-29 | 2017-02-15 | ユニ・チャーム株式会社 | 帯状シートにシールを施す融着装置 |
| JP6103945B2 (ja) | 2013-01-10 | 2017-03-29 | ユニ・チャーム株式会社 | 積み重ね装置及びウェブ部材を製造する方法 |
| JP6141023B2 (ja) | 2013-01-10 | 2017-06-07 | ユニ・チャーム株式会社 | トウを含むウエブ部材の製造方法 |
| JP2014189547A (ja) * | 2013-03-28 | 2014-10-06 | Lintec Corp | 嚥下物被覆体 |
| DE102017107468B4 (de) * | 2017-04-06 | 2019-02-21 | Lts Lohmann Therapie-Systeme Ag | Verfahren zur herstellung eines, insbesondere oralen, wirkstofflaminats und wirkstofflaminat, insbesondere orales wirkstofflaminat |
| JP7287032B2 (ja) | 2019-03-20 | 2023-06-06 | 株式会社リコー | シート、シート積層体、医薬品、シートの製造方法、及びシート積層体の製造方法 |
| US20220331263A1 (en) * | 2019-09-04 | 2022-10-20 | Vitiprints, LLC | Printed Delivery Device Having Supplements |
| CN112168700B (zh) * | 2020-10-29 | 2022-06-24 | 烟台博鑫制药机械有限公司 | 一种小型中药制丸机 |
| DE102021100779A1 (de) * | 2021-01-15 | 2022-07-21 | Lts Lohmann Therapie-Systeme Ag. | Mehrschichtiger oraler dünnfilm |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3696188A (en) * | 1971-06-16 | 1972-10-03 | Schering Corp | Laminated tablets |
| JPH0226493A (ja) | 1988-07-15 | 1990-01-29 | Nec Corp | 接続制御方式 |
| JPH0226493U (OSRAM) * | 1988-08-03 | 1990-02-21 | ||
| JPH02182154A (ja) * | 1988-12-30 | 1990-07-16 | Tsutomu Yokoi | 可食性フイルムおよび創傷被覆膜 |
| JPH05132570A (ja) * | 1991-11-14 | 1993-05-28 | Mitsubishi Rayon Co Ltd | 耐透湿性多糖フイルム |
| ATE252373T1 (de) * | 1994-08-04 | 2003-11-15 | Elan Drug Delivery Ltd | Feste verabreichungssysteme zur gesteuerten freisetzung von darin eingebauten molekülen sowie verfahren zu deren herstellung |
| JP2791317B2 (ja) * | 1995-12-26 | 1998-08-27 | 株式会社三和化学研究所 | 多層フィルム製剤 |
| DE19652188C2 (de) | 1996-12-16 | 2002-02-14 | Lohmann Therapie Syst Lts | Flache Arzneizubereitung zur Applikation und Freisetzung von Buprenorphin oder einer pharmakologisch vergleichbaren Substanz in der Mundhöhle und Verfahren zu ihrer Herstellung |
| JP2002191343A (ja) | 1997-06-09 | 2002-07-09 | Meiji Seika Kaisha Ltd | 積層体構造食品の製造方法 |
| JP3730081B2 (ja) * | 2000-04-10 | 2005-12-21 | 大鵬薬品工業株式会社 | フィルム状トローチ |
| JP4533542B2 (ja) * | 2001-02-07 | 2010-09-01 | 出光興産株式会社 | マイクロエンボスシートの製造方法 |
| JP4850346B2 (ja) * | 2001-03-15 | 2012-01-11 | 救急薬品工業株式会社 | 粘膜貼付剤 |
| US6472006B1 (en) * | 2001-04-05 | 2002-10-29 | Kraft Foods Holdings, Inc. | Oven-stable edible moisture barrier |
| WO2002087622A1 (en) * | 2001-04-24 | 2002-11-07 | Lintec Corporation | Oral preparations and supports for oral preparations |
| CN102188409A (zh) * | 2002-07-22 | 2011-09-21 | 莫诺索尔克斯有限公司 | 速溶剂型的包装和分配 |
| CA2504814A1 (en) * | 2002-12-02 | 2004-06-17 | Kyukyu Pharmaceutical Co., Ltd. | Process for producing edible orally administered agent of laminate film form and compression bonding apparatus |
| JP4427981B2 (ja) * | 2003-06-26 | 2010-03-10 | 救急薬品工業株式会社 | フィルム状口腔内投与剤の打ち抜き成型方法 |
-
2004
- 2004-06-02 JP JP2004164367A patent/JP4547994B2/ja not_active Expired - Lifetime
-
2005
- 2005-05-25 WO PCT/JP2005/009535 patent/WO2005117803A1/ja not_active Ceased
- 2005-05-25 US US11/578,427 patent/US8357415B2/en active Active
- 2005-05-25 EP EP05743754.3A patent/EP1752127B1/en not_active Expired - Lifetime
-
2012
- 2012-11-01 US US13/666,227 patent/US20130064874A1/en not_active Abandoned
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