JP2005206527A5 - - Google Patents
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- JP2005206527A5 JP2005206527A5 JP2004015125A JP2004015125A JP2005206527A5 JP 2005206527 A5 JP2005206527 A5 JP 2005206527A5 JP 2004015125 A JP2004015125 A JP 2004015125A JP 2004015125 A JP2004015125 A JP 2004015125A JP 2005206527 A5 JP2005206527 A5 JP 2005206527A5
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- JP
- Japan
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Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004015125A JP4573223B2 (ja) | 2004-01-23 | 2004-01-23 | 光学活性ｔｒａｎｓ−４−アミノ−１−ベンジル−３−ピロリジノールの製造方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2004015125A JP4573223B2 (ja) | 2004-01-23 | 2004-01-23 | 光学活性ｔｒａｎｓ−４−アミノ−１−ベンジル−３−ピロリジノールの製造方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005206527A JP2005206527A (ja) | 2005-08-04 |
| JP2005206527A5 true JP2005206527A5 (enExample) | 2007-03-01 |
| JP4573223B2 JP4573223B2 (ja) | 2010-11-04 |
Family
ID=34900685
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004015125A Expired - Fee Related JP4573223B2 (ja) | 2004-01-23 | 2004-01-23 | 光学活性ｔｒａｎｓ−４−アミノ−１−ベンジル−３−ピロリジノールの製造方法 |
Country Status (1)
| Country | Link |
|---|---|
| JP (1) | JP4573223B2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| SI2712358T1 (sl) | 2011-05-13 | 2017-03-31 | Array Biopharma, Inc. | Spojine pirolidinil sečnine, pirolidinil tiosečnine in pirolidinil gvanidina kot inhibitorji kinaze trka |
| WO2014078408A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | Bicyclic heteroaryl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
| RU2664541C2 (ru) | 2012-11-13 | 2018-08-20 | Эррэй Биофарма Инк. | Бициклические соединения мочевины, тиомочевины, гуанидина и цианогуанидина, пригодные для лечения боли |
| WO2014078325A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | N-(monocyclic aryl),n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
| WO2014078328A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | N-bicyclic aryl,n'-pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
| WO2014078331A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | N-(arylalkyl)-n'-pyrazolyl-urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
| US9809578B2 (en) | 2012-11-13 | 2017-11-07 | Array Biopharma Inc. | Pyrazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trkA kinase inhibitors |
| WO2014078322A1 (en) | 2012-11-13 | 2014-05-22 | Array Biopharma Inc. | Thiazolyl and oxazolyl urea, thiourea, guanidine and cyanoguanidine compounds as trka kinase inhibitors |
| ES2664331T3 (es) | 2012-11-13 | 2018-04-19 | Array Biopharma, Inc. | Compuestos de N-pirrolidinilo, N'-pirazolilurea, tiourea, guanidina y cianoguanidina como inhibidores de la cinasa Trka |
| US9790178B2 (en) | 2012-11-13 | 2017-10-17 | Array Biopharma Inc. | Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors |
| US9828360B2 (en) | 2012-11-13 | 2017-11-28 | Array Biopharma Inc. | Pyrrolidinyl urea, thiourea, guanidine and cyanoguanidine compounds as TrkA kinase inhibitors |
| PT3154959T (pt) | 2014-05-15 | 2019-09-24 | Array Biopharma Inc | 1-((3s,4r)-4-(3-fluorofenil)-1-(2-metoxietil)-pirrolidin-3-il)-3-(4-metil-3-(2-metilpirimidin-5-il)-1-fenil-1h-pirazol-5-il)ureia como inibidor da cinase trka |
| CN113429328A (zh) * | 2021-08-09 | 2021-09-24 | 艾琪康医药科技（上海）有限公司 | 手性3，3-二氟-4-氨基吡咯烷衍生物及其制备方法 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3906365A1 (de) * | 1988-07-15 | 1990-01-18 | Bayer Ag | 7-(1-pyrrolidinyl)-3-chinolon- und -naphthyridoncarbonsaeure-derivate, verfahren sowie substituierte (oxa)diazabicyclooctane und -nonane als zwischenprodukte zu ihrer herstellung, und sie enthaltende antibakterielle mittel und futterzusatzstoffe |
| JP2995704B2 (ja) * | 1989-02-17 | 1999-12-27 | 東京化成工業株式会社 | 光学活性な１ｈ−３−アミノピロリジン化合物の製造法 |
| JPH0672903A (ja) * | 1992-08-26 | 1994-03-15 | Daicel Chem Ind Ltd | 光学異性体分離法 |
| JP3716376B2 (ja) * | 1995-10-26 | 2005-11-16 | 東レ・ファインケミカル株式会社 | 光学分割剤およびそれを用いた光学活性３−アミノピロリジン誘導体の製造法 |
| JPH09176115A (ja) * | 1995-12-28 | 1997-07-08 | Koei Chem Co Ltd | 光学活性なｎ−ベンジル−３−アミノピロリジンの製造方法 |
| JP4788027B2 (ja) * | 2000-08-10 | 2011-10-05 | 東レ・ファインケミカル株式会社 | アミノピロリジン誘導体の製造法 |
| JP4780542B2 (ja) * | 2001-06-15 | 2011-09-28 | 東レ・ファインケミカル株式会社 | ３−アミノピロリジン誘導体の製造方法 |
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2004
- 2004-01-23 JP JP2004015125A patent/JP4573223B2/ja not_active Expired - Fee Related