JP2005179367A5 - - Google Patents

Info

Publication number

JP2005179367A5

JP2005179367A5 JP2004371968A JP2004371968A JP2005179367A5 JP 2005179367 A5 JP2005179367 A5 JP 2005179367A5 JP 2004371968 A JP2004371968 A JP 2004371968A JP 2004371968 A JP2004371968 A JP 2004371968A JP 2005179367 A5 JP2005179367 A5 JP 2005179367A5

Authority

JP

Japan

Prior art keywords

ecdysteroid

use according

cosmetic

composition

hair loss

Prior art date

2004-12-22

Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)

Pending

Links

• Espacenet
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• 150000002061 ecdysteroids Chemical class 0.000 claims 9
• 239000002537 cosmetic Substances 0.000 claims 3
• LQGNCUXDDPRDJH-UHFFFAOYSA-N 3'-GMP Natural products C1C(O)C(O)CC2(C)C(C(O)CC3(C(C(C)(O)C(O)CCC(C)C)CCC33O)C)C3=CC(=O)C21 LQGNCUXDDPRDJH-UHFFFAOYSA-N 0.000 claims 2
• 201000004384 Alopecia Diseases 0.000 claims 2
• PJYYBCXMCWDUAZ-YKDQUOQBSA-N Ponasterone A Natural products O=C1[C@H]2[C@@](C)([C@@H]3C([C@@]4(O)[C@@](C)([C@H]([C@@](O)([C@@H](O)CCC(C)C)C)CC4)CC3)=C1)C[C@H](O)[C@H](O)C2 PJYYBCXMCWDUAZ-YKDQUOQBSA-N 0.000 claims 2
• 230000003676 hair loss Effects 0.000 claims 2
• 208000024963 hair loss Diseases 0.000 claims 2
• ODENAQIZHMFEAO-BQBPTSSQSA-N (2s,3r,5r,9r,10r,13r,14s,17s)-17-[(2r,3r,5r)-5-ethyl-2,3-dihydroxy-6-(hydroxymethyl)hept-6-en-2-yl]-2,3,14-trihydroxy-10,13-dimethyl-2,3,4,5,9,11,12,15,16,17-decahydro-1h-cyclopenta[a]phenanthren-6-one Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@](C)(O)[C@H](O)C[C@@H](CC)C(=C)CO)CC[C@]33O)C)C3=CC(=O)[C@@H]21 ODENAQIZHMFEAO-BQBPTSSQSA-N 0.000 claims 1
• PJYYBCXMCWDUAZ-JJJZTNILSA-N 2,3,14,20,22-pentahydroxy-(2β,3β,5β,22R)-Cholest-7-en-6-one Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@](C)(O)[C@H](O)CCC(C)C)CC[C@]33O)C)C3=CC(=O)[C@@H]21 PJYYBCXMCWDUAZ-JJJZTNILSA-N 0.000 claims 1
• NKDFYOWSKOHCCO-YPVLXUMRSA-N 20-hydroxyecdysone Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@](C)(O)[C@H](O)CCC(C)(O)C)CC[C@]33O)C)C3=CC(=O)[C@@H]21 NKDFYOWSKOHCCO-YPVLXUMRSA-N 0.000 claims 1
• HXWZQRICWSADMH-SEHXZECUSA-N 20-hydroxyecdysone Natural products CC(C)(C)CC[C@@H](O)[C@@](C)(O)[C@H]1CC[C@@]2(O)C3=CC(=O)[C@@H]4C[C@@H](O)[C@@H](O)C[C@]4(C)[C@H]3CC[C@]12C HXWZQRICWSADMH-SEHXZECUSA-N 0.000 claims 1
• ODENAQIZHMFEAO-UHFFFAOYSA-N Ajugasterone B Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C)(O)C(O)CC(CC)C(=C)CO)CCC33O)C)C3=CC(=O)C21 ODENAQIZHMFEAO-UHFFFAOYSA-N 0.000 claims 1
• UPEZCKBFRMILAV-JNEQICEOSA-N Ecdysone Natural products O=C1[C@H]2[C@@](C)([C@@H]3C([C@@]4(O)[C@@](C)([C@H]([C@H]([C@@H](O)CCC(O)(C)C)C)CC4)CC3)=C1)C[C@H](O)[C@H](O)C2 UPEZCKBFRMILAV-JNEQICEOSA-N 0.000 claims 1
• DCEFCUHVANGEOE-UHFFFAOYSA-N Ecdysterone Natural products CC(CC(C)(C)O)C(O)C(C)(O)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3CCC12C DCEFCUHVANGEOE-UHFFFAOYSA-N 0.000 claims 1
• LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims 1
• LRJUYAVTHIEHAI-UHFFFAOYSA-N Muristeron A Natural products C1C(O)C(O)CC2(C)C(C(O)CC3(C(C(C)(O)C(O)CCC(C)C)CCC33O)C)C3=CC(=O)C21O LRJUYAVTHIEHAI-UHFFFAOYSA-N 0.000 claims 1
• LRJUYAVTHIEHAI-LHBNDURVSA-N Muristerone Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)[C@@H]([C@H](O)C[C@@]3([C@@H]([C@@](C)(O)[C@H](O)CCC(C)C)CC[C@]33O)C)C3=CC(=O)[C@@]21O LRJUYAVTHIEHAI-LHBNDURVSA-N 0.000 claims 1
• PXCOYCUFJMMDCP-UHFFFAOYSA-N Ponasteron C Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C)(O)C(O)CC(O)C(C)C)CCC33O)C)C3=CC(=O)C21O PXCOYCUFJMMDCP-UHFFFAOYSA-N 0.000 claims 1
• IADYMQZFKRTNKH-UHFFFAOYSA-N Ponasterone B Natural products CC(C)CCC(O)C(C)(O)C1CCC2(O)C3=CCC4CC(O)C(O)CC4(C)C3CCC12C IADYMQZFKRTNKH-UHFFFAOYSA-N 0.000 claims 1
• UOGSHXJXNPQJMT-UHFFFAOYSA-N Ponasterone C Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C)(O)C(O)CCC(C)C)CCC33O)C)C3=CC(=O)C21O UOGSHXJXNPQJMT-UHFFFAOYSA-N 0.000 claims 1
• 239000000654 additive Substances 0.000 claims 1
• RVMAVGROMRTERF-UHFFFAOYSA-N ajugasterone C Natural products CC(C)CCC(O)C(C)C1CCC2(O)C3=CC(=O)C4CC(O)C(O)CC4(C)C3C(O)CC12C RVMAVGROMRTERF-UHFFFAOYSA-N 0.000 claims 1
• LQGNCUXDDPRDJH-CNDNGNGWSA-N ajugasterone C Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)C([C@H](O)C[C@@]3([C@@H]([C@@](C)(O)[C@H](O)CCC(C)C)CC[C@]33O)C)C3=CC(=O)[C@@H]21 LQGNCUXDDPRDJH-CNDNGNGWSA-N 0.000 claims 1
• UPEZCKBFRMILAV-UHFFFAOYSA-N alpha-Ecdysone Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C(O)CCC(C)(C)O)C)CCC33O)C)C3=CC(=O)C21 UPEZCKBFRMILAV-UHFFFAOYSA-N 0.000 claims 1
• NKDFYOWSKOHCCO-UHFFFAOYSA-N beta-ecdysone Natural products C1C(O)C(O)CC2(C)C(CCC3(C(C(C)(O)C(O)CCC(C)(O)C)CCC33O)C)C3=CC(=O)C21 NKDFYOWSKOHCCO-UHFFFAOYSA-N 0.000 claims 1
• 239000008406 cosmetic ingredient Substances 0.000 claims 1
• UPEZCKBFRMILAV-JMZLNJERSA-N ecdysone Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@H]([C@H](O)CCC(C)(C)O)C)CC[C@]33O)C)C3=CC(=O)[C@@H]21 UPEZCKBFRMILAV-JMZLNJERSA-N 0.000 claims 1
• 238000004519 manufacturing process Methods 0.000 claims 1
• 238000000034 method Methods 0.000 claims 1
• 239000003960 organic solvent Substances 0.000 claims 1
• PJYYBCXMCWDUAZ-VNHCOKMVSA-N ponasterone B Chemical compound C1[C@H](O)[C@H](O)C[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@](C)(O)[C@H](O)CCC(C)C)CC[C@]33O)C)C3=CC(=O)[C@@H]21 PJYYBCXMCWDUAZ-VNHCOKMVSA-N 0.000 claims 1
• PXCOYCUFJMMDCP-CEPQAZHYSA-N ponasterone C Chemical compound C1[C@@H](O)[C@@H](O)C[C@]2(C)[C@@H](CC[C@@]3([C@@H]([C@@](C)(O)[C@H](O)C[C@H](O)C(C)C)CC[C@]33O)C)C3=CC(=O)[C@@]21O PXCOYCUFJMMDCP-CEPQAZHYSA-N 0.000 claims 1
• 230000003658 preventing hair loss Effects 0.000 claims 1
• 210000004761 scalp Anatomy 0.000 claims 1
• XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 1