JP2005097255A5 - - Google Patents
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- Publication number
- JP2005097255A5 JP2005097255A5 JP2004212054A JP2004212054A JP2005097255A5 JP 2005097255 A5 JP2005097255 A5 JP 2005097255A5 JP 2004212054 A JP2004212054 A JP 2004212054A JP 2004212054 A JP2004212054 A JP 2004212054A JP 2005097255 A5 JP2005097255 A5 JP 2005097255A5
- Authority
- JP
- Japan
- Prior art keywords
- dunaliella
- preparation
- use according
- effective amount
- fibrate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 241000195634 Dunaliella Species 0.000 claims 12
- 239000003795 chemical substances by application Substances 0.000 claims 7
- 102000023984 PPAR alpha Human genes 0.000 claims 6
- YASAKCUCGLMORW-UHFFFAOYSA-N Rosiglitazone Chemical compound C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O YASAKCUCGLMORW-UHFFFAOYSA-N 0.000 claims 6
- 108020005497 Nuclear hormone receptor Proteins 0.000 claims 5
- 239000012190 activator Substances 0.000 claims 5
- 102000006255 nuclear receptors Human genes 0.000 claims 5
- 108020004017 nuclear receptors Proteins 0.000 claims 5
- 108091008725 peroxisome proliferator-activated receptors alpha Proteins 0.000 claims 5
- ZOBPZXTWZATXDG-UHFFFAOYSA-N 1,3-thiazolidine-2,4-dione Chemical compound O=C1CSC(=O)N1 ZOBPZXTWZATXDG-UHFFFAOYSA-N 0.000 claims 4
- 102000000536 PPAR gamma Human genes 0.000 claims 4
- 108010016731 PPAR gamma Proteins 0.000 claims 4
- 229940123464 Thiazolidinedione Drugs 0.000 claims 4
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 claims 4
- 239000003814 drug Substances 0.000 claims 4
- 229940125753 fibrate Drugs 0.000 claims 4
- HYAFETHFCAUJAY-UHFFFAOYSA-N pioglitazone Chemical compound N1=CC(CC)=CC=C1CCOC(C=C1)=CC=C1CC1C(=O)NC(=O)S1 HYAFETHFCAUJAY-UHFFFAOYSA-N 0.000 claims 4
- 239000000843 powder Substances 0.000 claims 4
- 241000195493 Cryptophyta Species 0.000 claims 3
- 239000008194 pharmaceutical composition Substances 0.000 claims 3
- AFSHNJLKCYAWRX-UHFFFAOYSA-N 4-[(5-chloronaphthalen-2-yl)methyl]-5h-1,2,3,5-oxathiadiazole 2-oxide Chemical compound C=1C=C2C(Cl)=CC=CC2=CC=1CC1=NS(=O)ON1 AFSHNJLKCYAWRX-UHFFFAOYSA-N 0.000 claims 2
- MVDXXGIBARMXSA-PYUWXLGESA-N 5-[[(2r)-2-benzyl-3,4-dihydro-2h-chromen-6-yl]methyl]-1,3-thiazolidine-2,4-dione Chemical compound S1C(=O)NC(=O)C1CC1=CC=C(O[C@@H](CC=2C=CC=CC=2)CC2)C2=C1 MVDXXGIBARMXSA-PYUWXLGESA-N 0.000 claims 2
- YVQKIDLSVHRBGZ-UHFFFAOYSA-N 5-[[4-[2-hydroxy-2-(5-methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione Chemical compound CC=1OC(C=2C=CC=CC=2)=NC=1C(O)COC(C=C1)=CC=C1CC1SC(=O)NC1=O YVQKIDLSVHRBGZ-UHFFFAOYSA-N 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- KPSRODZRAIWAKH-JTQLQIEISA-N Ciprofibrate Natural products C1=CC(OC(C)(C)C(O)=O)=CC=C1[C@H]1C(Cl)(Cl)C1 KPSRODZRAIWAKH-JTQLQIEISA-N 0.000 claims 2
- HEMJJKBWTPKOJG-UHFFFAOYSA-N Gemfibrozil Chemical compound CC1=CC=C(C)C(OCCCC(C)(C)C(O)=O)=C1 HEMJJKBWTPKOJG-UHFFFAOYSA-N 0.000 claims 2
- 229940080774 Peroxisome proliferator-activated receptor gamma agonist Drugs 0.000 claims 2
- 239000000556 agonist Substances 0.000 claims 2
- 229940062310 avandia Drugs 0.000 claims 2
- 229960000516 bezafibrate Drugs 0.000 claims 2
- IIBYAHWJQTYFKB-UHFFFAOYSA-N bezafibrate Chemical compound C1=CC(OC(C)(C)C(O)=O)=CC=C1CCNC(=O)C1=CC=C(Cl)C=C1 IIBYAHWJQTYFKB-UHFFFAOYSA-N 0.000 claims 2
- YZFWTZACSRHJQD-UHFFFAOYSA-N ciglitazone Chemical compound C=1C=C(CC2C(NC(=O)S2)=O)C=CC=1OCC1(C)CCCCC1 YZFWTZACSRHJQD-UHFFFAOYSA-N 0.000 claims 2
- 229950009226 ciglitazone Drugs 0.000 claims 2
- 229960002174 ciprofibrate Drugs 0.000 claims 2
- KPSRODZRAIWAKH-UHFFFAOYSA-N ciprofibrate Chemical compound C1=CC(OC(C)(C)C(O)=O)=CC=C1C1C(Cl)(Cl)C1 KPSRODZRAIWAKH-UHFFFAOYSA-N 0.000 claims 2
- 229960001214 clofibrate Drugs 0.000 claims 2
- KNHUKKLJHYUCFP-UHFFFAOYSA-N clofibrate Chemical group CCOC(=O)C(C)(C)OC1=CC=C(Cl)C=C1 KNHUKKLJHYUCFP-UHFFFAOYSA-N 0.000 claims 2
- QQKNSPHAFATFNQ-UHFFFAOYSA-N darglitazone Chemical compound CC=1OC(C=2C=CC=CC=2)=NC=1CCC(=O)C(C=C1)=CC=C1CC1SC(=O)NC1=O QQKNSPHAFATFNQ-UHFFFAOYSA-N 0.000 claims 2
- 229950006689 darglitazone Drugs 0.000 claims 2
- 206010012601 diabetes mellitus Diseases 0.000 claims 2
- 229950002375 englitazone Drugs 0.000 claims 2
- 229960002297 fenofibrate Drugs 0.000 claims 2
- YMTINGFKWWXKFG-UHFFFAOYSA-N fenofibrate Chemical compound C1=CC(OC(C)(C)C(=O)OC(C)C)=CC=C1C(=O)C1=CC=C(Cl)C=C1 YMTINGFKWWXKFG-UHFFFAOYSA-N 0.000 claims 2
- 229960003627 gemfibrozil Drugs 0.000 claims 2
- 229960005095 pioglitazone Drugs 0.000 claims 2
- 229960004586 rosiglitazone Drugs 0.000 claims 2
- SUFUKZSWUHZXAV-BTJKTKAUSA-N rosiglitazone maleate Chemical group [H+].[H+].[O-]C(=O)\C=C/C([O-])=O.C=1C=CC=NC=1N(C)CCOC(C=C1)=CC=C1CC1SC(=O)NC1=O SUFUKZSWUHZXAV-BTJKTKAUSA-N 0.000 claims 2
- GXPHKUHSUJUWKP-UHFFFAOYSA-N troglitazone Chemical compound C1CC=2C(C)=C(O)C(C)=C(C)C=2OC1(C)COC(C=C1)=CC=C1CC1SC(=O)NC1=O GXPHKUHSUJUWKP-UHFFFAOYSA-N 0.000 claims 2
- 229960001641 troglitazone Drugs 0.000 claims 2
- GXPHKUHSUJUWKP-NTKDMRAZSA-N troglitazone Natural products C([C@@]1(OC=2C(C)=C(C(=C(C)C=2CC1)O)C)C)OC(C=C1)=CC=C1C[C@H]1SC(=O)NC1=O GXPHKUHSUJUWKP-NTKDMRAZSA-N 0.000 claims 2
- 241000195633 Dunaliella salina Species 0.000 claims 1
- 108010028924 PPAR alpha Proteins 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US10/668,601 US7264813B2 (en) | 2003-09-24 | 2003-09-24 | Therapeutic uses of Dunaliella powder |
| US10/668601 | 2003-09-24 |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009187809A Division JP5356946B2 (ja) | 2003-09-24 | 2009-08-13 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005097255A JP2005097255A (ja) | 2005-04-14 |
| JP2005097255A5 true JP2005097255A5 (https=) | 2005-09-29 |
| JP5020463B2 JP5020463B2 (ja) | 2012-09-05 |
Family
ID=34313520
Family Applications (5)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2004212054A Expired - Fee Related JP5020463B2 (ja) | 2003-09-24 | 2004-07-20 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2009187809A Expired - Lifetime JP5356946B2 (ja) | 2003-09-24 | 2009-08-13 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2013126599A Withdrawn JP2013177457A (ja) | 2003-09-24 | 2013-06-17 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2016104166A Expired - Fee Related JP6321074B2 (ja) | 2003-09-24 | 2016-05-25 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2017235555A Expired - Lifetime JP6490782B2 (ja) | 2003-09-24 | 2017-12-07 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
Family Applications After (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2009187809A Expired - Lifetime JP5356946B2 (ja) | 2003-09-24 | 2009-08-13 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2013126599A Withdrawn JP2013177457A (ja) | 2003-09-24 | 2013-06-17 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2016104166A Expired - Fee Related JP6321074B2 (ja) | 2003-09-24 | 2016-05-25 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
| JP2017235555A Expired - Lifetime JP6490782B2 (ja) | 2003-09-24 | 2017-12-07 | ドナリエラ属（Ｄｕｎａｌｉｅｌｌａ）の粉末の治療的使用 |
Country Status (5)
| Country | Link |
|---|---|
| US (3) | US7264813B2 (https=) |
| EP (2) | EP1522310B1 (https=) |
| JP (5) | JP5020463B2 (https=) |
| AT (1) | ATE548046T1 (https=) |
| IL (1) | IL162987A (https=) |
Families Citing this family (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2007210917A (ja) * | 2006-02-08 | 2007-08-23 | Kochi Univ | 脂肪細胞縮小化剤、医薬品及び飲食品 |
| WO2007109824A1 (en) * | 2006-03-24 | 2007-10-04 | Ian Simon Tracton | Stable packaged dosage form and process therefor |
| JP2008222555A (ja) * | 2007-03-08 | 2008-09-25 | Nagasakiken Koritsu Daigaku Hojin | アディポネクチン受容体発現増加剤 |
| WO2009105048A2 (fr) * | 2008-02-19 | 2009-08-27 | Rached Smida | Nouvelles applications du hdl reconstitué |
| JP5443470B2 (ja) * | 2008-04-29 | 2014-03-19 | 株式会社日健総本社 | 眼障害の治療方法 |
| US20100303989A1 (en) | 2008-10-14 | 2010-12-02 | Solazyme, Inc. | Microalgal Flour |
| JP5733592B2 (ja) * | 2008-10-20 | 2015-06-10 | 株式会社日健総本社 | 脂質異常治療薬の副作用防止物質 |
| US8747834B2 (en) | 2009-03-03 | 2014-06-10 | Solazyme, Inc. | Methods of treating impaired glucose metabolism via administration of algal biomass |
| WO2011070568A1 (en) | 2009-12-10 | 2011-06-16 | Nikken Sohonsha Corporation | Method for treating psoriasis |
| WO2011109559A2 (en) | 2010-03-02 | 2011-09-09 | Kyle Terrill | Structures and methods of fabricating dual gate devices |
| US10098371B2 (en) | 2013-01-28 | 2018-10-16 | Solazyme Roquette Nutritionals, LLC | Microalgal flour |
| FR3009619B1 (fr) | 2013-08-07 | 2017-12-29 | Roquette Freres | Compositions de biomasse de microalgues riches en proteines de qualite sensorielle optimisee |
| GB201718822D0 (en) | 2017-11-14 | 2017-12-27 | Univ Greenwich | Production of dunaliella |
| JP6947665B2 (ja) * | 2018-03-13 | 2021-10-13 | アイカ工業株式会社 | 光硬化性粘着樹脂組成物 |
| WO2020202152A1 (en) * | 2019-04-01 | 2020-10-08 | Tel Hashomer Medical Research Infrastructure And Services Ltd. | Dunaliella alga preparation for prevention and/or treatment of a neurodegenerative disease, a disorder associated with protein misfolding and cognitive decline |
Family Cites Families (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4199895A (en) | 1977-05-25 | 1980-04-29 | Yeda Research And Development Co. Ltd. | Production of glycerol, carotenes and algae meal |
| USPP4511P (en) | 1978-06-26 | 1980-03-18 | Yeda Research & Development Co. Ltd. | Alga strain |
| DE3729209A1 (de) | 1987-09-01 | 1989-03-09 | Boehringer Mannheim Gmbh | Verwendung von bezafibrat zur behandlung von diabetes |
| IL87260A (en) * | 1988-02-25 | 1991-12-15 | Tanaka Yoshio | Encapsulated food containing dunaliella algae and its production |
| US5190970A (en) * | 1990-10-19 | 1993-03-02 | E. R. Squibb & Sons, Inc. | Method for preventing onset of or treating Type II diabetes employing a cholesterol lowering drug alone or in combination with an ace inhibitor |
| US5219888A (en) | 1992-03-31 | 1993-06-15 | American Cyanamid Company | Use of retinoids for the treatment of coronary artery disease |
| DE69327100T2 (de) | 1992-06-04 | 2000-04-13 | Betatene Pty. Ltd., Cheltenham | Gemisch mit hohem gehalt an cis beta-carotin |
| US6262109B1 (en) * | 1995-12-22 | 2001-07-17 | Henkel Corporation | Methods of preventing and/or treating high serum levels of cholesterol and/or lipids |
| ATE259227T1 (de) | 1995-09-18 | 2004-02-15 | Ligand Pharm Inc | Behandlung von niddm (nichtinsulinabhängige diabetes mellitus) mit rxr agonisten |
| US6028052A (en) * | 1995-09-18 | 2000-02-22 | Ligand Pharmaceuticals Incorporated | Treating NIDDM with RXR agonists |
| IL119224A (en) | 1996-09-09 | 2002-11-10 | Hadasit Med Res Service | Medicament for protection from effects of irradiation |
| JP3037628B2 (ja) * | 1997-03-06 | 2000-04-24 | マイクロアルジェコーポレーション株式会社 | 健康補助食品用軟カプセルの製法 |
| GB9712866D0 (en) * | 1997-06-18 | 1997-08-20 | Smithkline Beecham Plc | Novel method of treatment |
| US6083497A (en) * | 1997-11-05 | 2000-07-04 | Geltex Pharmaceuticals, Inc. | Method for treating hypercholesterolemia with unsubstituted polydiallylamine polymers |
| KR20010042373A (ko) | 1998-03-30 | 2001-05-25 | 린다 에스. 스티븐슨 | 핵 수용체 활성을 조절하는 방법 및 화합물 |
| JP2000080047A (ja) * | 1998-06-30 | 2000-03-21 | Takeda Chem Ind Ltd | 医 薬 |
| WO2000000195A1 (en) | 1998-06-30 | 2000-01-06 | Takeda Chemical Industries, Ltd. | Pharmaceutical composition for the treatment of diabetes |
| IL126447A (en) * | 1998-10-04 | 2004-09-27 | Vascular Biogenics Ltd | An immune preparation that confers tolerance in oral administration and its use in the prevention and / or treatment of atherosclerosis |
| JP2002533410A (ja) * | 1998-12-23 | 2002-10-08 | ジー．ディー．サール エルエルシー | 心臓血管に適用するためのコレステリルエステル転送タンパク質阻害剤およびフィブリン酸誘導体の組み合わせ |
| US6914073B2 (en) * | 1999-03-18 | 2005-07-05 | Bristol Myers Squibb Company | Vitamin formulation for cardiovascular health |
| FR2795961B1 (fr) * | 1999-07-09 | 2004-05-28 | Ethypharm Lab Prod Ethiques | Composition pharmaceutique contenant du fenofibrate micronise, un tensioactif et un derive cellulosique liant et procede de preparation |
| AU7586600A (en) | 1999-09-14 | 2001-04-17 | Ligand Pharmaceuticals Incorporated | Rxr modulators with improved pharmacologic profile |
| US6680387B2 (en) * | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
| GB0019226D0 (en) * | 2000-08-04 | 2000-09-27 | Smithkline Beecham Plc | Novel pharmaceutical |
| AU2002333655A1 (en) | 2001-09-25 | 2003-04-07 | Smithkline Beecham Corporation | Bicyclic heterocycles as rxr ligands |
| IN189624B (https=) * | 2001-10-23 | 2003-03-29 | Ajanta Pharma Ltd | |
| JP3978582B2 (ja) * | 2001-12-19 | 2007-09-19 | 株式会社日健総本社 | カロチノイドの製造方法 |
| US20030212138A1 (en) * | 2002-01-14 | 2003-11-13 | Pharmacia Corporation | Combinations of peroxisome proliferator-activated receptor-alpha agonists and cyclooxygenase-2 selective inhibitors and therapeutic uses therefor |
-
2003
- 2003-09-24 US US10/668,601 patent/US7264813B2/en not_active Expired - Lifetime
-
2004
- 2004-07-13 IL IL162987A patent/IL162987A/en active IP Right Grant
- 2004-07-20 JP JP2004212054A patent/JP5020463B2/ja not_active Expired - Fee Related
- 2004-08-12 EP EP04019206A patent/EP1522310B1/en not_active Expired - Lifetime
- 2004-08-12 EP EP10010882A patent/EP2269620A1/en not_active Withdrawn
- 2004-08-12 AT AT04019206T patent/ATE548046T1/de active
-
2007
- 2007-07-10 US US11/822,786 patent/US7763255B2/en not_active Expired - Lifetime
-
2009
- 2009-08-13 JP JP2009187809A patent/JP5356946B2/ja not_active Expired - Lifetime
-
2010
- 2010-05-11 US US12/777,757 patent/US8343549B2/en not_active Expired - Fee Related
-
2013
- 2013-06-17 JP JP2013126599A patent/JP2013177457A/ja not_active Withdrawn
-
2016
- 2016-05-25 JP JP2016104166A patent/JP6321074B2/ja not_active Expired - Fee Related
-
2017
- 2017-12-07 JP JP2017235555A patent/JP6490782B2/ja not_active Expired - Lifetime
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