JP2005060284A5 - - Google Patents
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- Publication number
- JP2005060284A5 JP2005060284A5 JP2003291308A JP2003291308A JP2005060284A5 JP 2005060284 A5 JP2005060284 A5 JP 2005060284A5 JP 2003291308 A JP2003291308 A JP 2003291308A JP 2003291308 A JP2003291308 A JP 2003291308A JP 2005060284 A5 JP2005060284 A5 JP 2005060284A5
- Authority
- JP
- Japan
- Prior art keywords
- gel
- polymerizing
- solution containing
- precursor solution
- protein crystallization
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002425 crystallisation Methods 0.000 claims 6
- 230000008025 crystallization Effects 0.000 claims 6
- 230000000379 polymerizing effect Effects 0.000 claims 6
- 239000002243 precursor Substances 0.000 claims 6
- 102000004169 proteins and genes Human genes 0.000 claims 6
- 108090000623 proteins and genes Proteins 0.000 claims 6
- 229920000536 2-Acrylamido-2-methylpropane sulfonic acid Polymers 0.000 claims 2
- XHZPRMZZQOIPDS-UHFFFAOYSA-N 2-Methyl-2-[(1-oxo-2-propenyl)amino]-1-propanesulfonic acid Chemical compound OS(=O)(=O)CC(C)(C)NC(=O)C=C XHZPRMZZQOIPDS-UHFFFAOYSA-N 0.000 claims 2
- SVTBMSDMJJWYQN-UHFFFAOYSA-N 2-methylpentane-2,4-diol Chemical compound CC(O)CC(C)(C)O SVTBMSDMJJWYQN-UHFFFAOYSA-N 0.000 claims 2
- VKPCTUNZUCHTOH-UHFFFAOYSA-N 4-chloro-6-(dimethylamino)-2-methylhex-1-en-3-one Chemical class C(=O)(C(=C)C)C(CCN(C)C)Cl VKPCTUNZUCHTOH-UHFFFAOYSA-N 0.000 claims 2
- HRPVXLWXLXDGHG-UHFFFAOYSA-N Acrylamide Chemical compound NC(=O)C=C HRPVXLWXLXDGHG-UHFFFAOYSA-N 0.000 claims 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 claims 2
- 230000000717 retained effect Effects 0.000 claims 2
- WHNPOQXWAMXPTA-UHFFFAOYSA-N 3-methylbut-2-enamide Chemical compound CC(C)=CC(N)=O WHNPOQXWAMXPTA-UHFFFAOYSA-N 0.000 claims 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 claims 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 claims 1
- 235000011130 ammonium sulphate Nutrition 0.000 claims 1
- 239000000463 material Substances 0.000 claims 1
- 239000000178 monomer Substances 0.000 claims 1
- 229940093429 polyethylene glycol 6000 Drugs 0.000 claims 1
- -1 polyoxyethylene monoacrylate Polymers 0.000 claims 1
- XAEFZNCEHLXOMS-UHFFFAOYSA-M potassium benzoate Chemical compound [K+].[O-]C(=O)C1=CC=CC=C1 XAEFZNCEHLXOMS-UHFFFAOYSA-M 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- PRWXGRGLHYDWPS-UHFFFAOYSA-L sodium malonate Chemical compound [Na+].[Na+].[O-]C(=O)CC([O-])=O PRWXGRGLHYDWPS-UHFFFAOYSA-L 0.000 claims 1
- 229910000162 sodium phosphate Inorganic materials 0.000 claims 1
- 239000001488 sodium phosphate Substances 0.000 claims 1
- RYFMWSXOAZQYPI-UHFFFAOYSA-K trisodium phosphate Chemical compound [Na+].[Na+].[Na+].[O-]P([O-])([O-])=O RYFMWSXOAZQYPI-UHFFFAOYSA-K 0.000 claims 1
Priority Applications (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003291308A JP4323258B2 (ja) | 2003-08-11 | 2003-08-11 | 蛋白質結晶化剤およびその調製方法 |
| EP04771686A EP1666646A4 (en) | 2003-08-11 | 2004-08-10 | PROTEIN CRYSTALLIZATION DEVICE, METHOD FOR PROTEIN CRYSTALLIZATION, PROTEIN CRYSTALLIZING AGENTS AND PRODUCTION METHOD THEREFOR |
| US10/567,666 US20070181058A1 (en) | 2003-08-11 | 2004-08-10 | Protein crystallization apparatus, method of protein crystallization, protein crystallizing agent and process for preparing the same |
| CNB2004800295182A CN100355949C (zh) | 2003-08-11 | 2004-08-10 | 蛋白质结晶装置、蛋白质结晶方法、蛋白质结晶剂及其制备方法 |
| CN 200710092292 CN101029078A (zh) | 2003-08-11 | 2004-08-10 | 蛋白质结晶用凝胶 |
| PCT/JP2004/011725 WO2005014899A1 (ja) | 2003-08-11 | 2004-08-10 | 蛋白質結晶化装置、蛋白質結晶化方法、蛋白質結晶化剤、及びその調製方法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003291308A JP4323258B2 (ja) | 2003-08-11 | 2003-08-11 | 蛋白質結晶化剤およびその調製方法 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2005060284A JP2005060284A (ja) | 2005-03-10 |
| JP2005060284A5 true JP2005060284A5 (enExample) | 2006-09-21 |
| JP4323258B2 JP4323258B2 (ja) | 2009-09-02 |
Family
ID=34369027
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003291308A Expired - Fee Related JP4323258B2 (ja) | 2003-08-11 | 2003-08-11 | 蛋白質結晶化剤およびその調製方法 |
Country Status (2)
| Country | Link |
|---|---|
| JP (1) | JP4323258B2 (enExample) |
| CN (2) | CN101029078A (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102675412B (zh) * | 2011-03-16 | 2014-09-24 | 中国科学院化学研究所 | 一种制备蛋白质晶体的方法 |
| JP6848173B2 (ja) * | 2015-10-09 | 2021-03-24 | 東レ株式会社 | 含繊維結晶、含繊維結晶の製造方法、含繊維結晶の製造装置および薬剤ソーキング装置 |
| CN105810072A (zh) * | 2016-03-25 | 2016-07-27 | 淮海工学院 | 一种蛋白质结晶的教学试剂盒及其方法 |
| CN107099846B (zh) * | 2017-05-25 | 2019-05-10 | 西北工业大学 | 一种预布微、纳米级籽晶蛋白质结晶板的制备方法 |
| CN115260281A (zh) * | 2022-09-14 | 2022-11-01 | 华东理工大学 | 一种利用水凝胶调控提高蛋白质结晶效率的方法 |
Family Cites Families (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2764492A (en) * | 1991-10-09 | 1993-05-03 | Schering Corporation | Crystal forming device and automated crystallization system |
| JP2001136972A (ja) * | 1999-11-15 | 2001-05-22 | Mitsubishi Rayon Co Ltd | 核酸固定化高分子ゲル及びその製造方法 |
| WO2003053998A1 (en) * | 2001-12-11 | 2003-07-03 | Mitsubishi Rayon Co., Ltd. | Array for crystallizing protein, device for crystallizing protein and method of screening protein crystallization using the same |
-
2003
- 2003-08-11 JP JP2003291308A patent/JP4323258B2/ja not_active Expired - Fee Related
-
2004
- 2004-08-10 CN CN 200710092292 patent/CN101029078A/zh active Pending
- 2004-08-10 CN CNB2004800295182A patent/CN100355949C/zh not_active Expired - Fee Related
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