JP2005040037A - ジペプチドの製造方法、それに用いるペプチド生成酵素、およびペプチド生成酵素の製造方法 - Google Patents
ジペプチドの製造方法、それに用いるペプチド生成酵素、およびペプチド生成酵素の製造方法 Download PDFInfo
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- JP2005040037A JP2005040037A JP2003201820A JP2003201820A JP2005040037A JP 2005040037 A JP2005040037 A JP 2005040037A JP 2003201820 A JP2003201820 A JP 2003201820A JP 2003201820 A JP2003201820 A JP 2003201820A JP 2005040037 A JP2005040037 A JP 2005040037A
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- 229910021654 trace metal Inorganic materials 0.000 description 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 description 1
- 230000005030 transcription termination Effects 0.000 description 1
- 230000009466 transformation Effects 0.000 description 1
- 230000014616 translation Effects 0.000 description 1
- YWYZEGXAUVWDED-UHFFFAOYSA-N triammonium citrate Chemical compound [NH4+].[NH4+].[NH4+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O YWYZEGXAUVWDED-UHFFFAOYSA-N 0.000 description 1
- 101150019416 trpA gene Proteins 0.000 description 1
- 239000001974 tryptic soy broth Substances 0.000 description 1
- 108010050327 trypticase-soy broth Proteins 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- 238000005199 ultracentrifugation Methods 0.000 description 1
- 238000009281 ultraviolet germicidal irradiation Methods 0.000 description 1
- 238000011144 upstream manufacturing Methods 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 229940084592 vitamin b 12 0.01 mg Drugs 0.000 description 1
- 210000005253 yeast cell Anatomy 0.000 description 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Health & Medical Sciences (AREA)
- Zoology (AREA)
- General Chemical & Material Sciences (AREA)
- Molecular Biology (AREA)
- Microbiology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003201820A JP2005040037A (ja) | 2003-07-25 | 2003-07-25 | ジペプチドの製造方法、それに用いるペプチド生成酵素、およびペプチド生成酵素の製造方法 |
| CNB2004800213286A CN100385012C (zh) | 2003-07-25 | 2004-07-26 | 生产二肽的方法 |
| RU2006105494/13A RU2006105494A (ru) | 2003-07-25 | 2004-07-26 | Способ получения дипептидов |
| PCT/JP2004/010990 WO2005010196A1 (en) | 2003-07-25 | 2004-07-26 | Method for producing dipeptides |
| EP04748149A EP1658375A4 (en) | 2003-07-25 | 2004-07-26 | PROCESS FOR THE PREPARATION OF DIPEPTIDES |
| KR1020067001652A KR100760974B1 (ko) | 2003-07-25 | 2004-07-26 | 디펩티드의 제조 방법 |
| US11/330,076 US8084227B2 (en) | 2003-07-25 | 2006-01-12 | Method for producing dipeptides |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2003201820A JP2005040037A (ja) | 2003-07-25 | 2003-07-25 | ジペプチドの製造方法、それに用いるペプチド生成酵素、およびペプチド生成酵素の製造方法 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2005040037A true JP2005040037A (ja) | 2005-02-17 |
| JP2005040037A5 JP2005040037A5 (enExample) | 2006-09-07 |
Family
ID=34100525
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003201820A Pending JP2005040037A (ja) | 2003-07-25 | 2003-07-25 | ジペプチドの製造方法、それに用いるペプチド生成酵素、およびペプチド生成酵素の製造方法 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US8084227B2 (enExample) |
| EP (1) | EP1658375A4 (enExample) |
| JP (1) | JP2005040037A (enExample) |
| KR (1) | KR100760974B1 (enExample) |
| CN (1) | CN100385012C (enExample) |
| RU (1) | RU2006105494A (enExample) |
| WO (1) | WO2005010196A1 (enExample) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2180060B1 (en) * | 2003-01-24 | 2012-08-29 | Ajinomoto Co., Inc. | Method for produding alpha-L-aspartyl-L-phenylalanine-beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester |
| JP2005168405A (ja) | 2003-12-11 | 2005-06-30 | Ajinomoto Co Inc | ジペプチドの製造方法 |
| US20070190602A1 (en) * | 2005-12-27 | 2007-08-16 | Ajinomoto Co., Inc | Mutant protein having the peptide-synthesizing activity |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2857828C2 (enExample) * | 1977-01-27 | 1990-06-07 | Toyo Soda Mfg. Co., Ltd., Shinnanyo, Yamaguchi, Jp | |
| JPS5392729A (en) * | 1977-01-27 | 1978-08-15 | Toyo Soda Mfg Co Ltd | Adduct of dipeptide derivatives and amino acid derivatives and process for their preparation |
| DK72587D0 (da) * | 1987-02-13 | 1987-02-13 | Carlsberg Biotechnology Ltd | Fremgangsmaade til enzymatisk fremstilling af dipeptider |
| JPH0832717B2 (ja) | 1987-10-07 | 1996-03-29 | 味の素株式会社 | グルタミン誘導体の製造方法 |
| DK163435C (da) * | 1988-08-12 | 1992-07-20 | Carlsberg Biotechnology Ltd | Fremgangsmaade til enzymatisk fremstilling af dipeptider og derivater deraf |
| JP3473976B2 (ja) | 1992-10-29 | 2003-12-08 | 協和醗酵工業株式会社 | アラニルグルタミンの製造法 |
| CA2365594A1 (en) * | 1999-03-29 | 2000-10-05 | Holland Sweetener Company V.O.F. | Microbiological production method for .alpha.-l-aspartyl-l-phenylalanine |
| WO2003010189A1 (en) * | 2001-07-26 | 2003-02-06 | Ajinomoto Co., Inc. | Process for producing dipeptide, peptide synthase to be used therein and process for producing peptide synthase |
| EP2298905B1 (en) * | 2002-07-26 | 2014-02-12 | Ajinomoto Co., Inc. | Novel peptide-forming enzyme gene |
| EP2180060B1 (en) * | 2003-01-24 | 2012-08-29 | Ajinomoto Co., Inc. | Method for produding alpha-L-aspartyl-L-phenylalanine-beta-ester and method for producing alpha-L-aspartyl-L-phenylalanine-alpha-methyl ester |
| JP2005168405A (ja) * | 2003-12-11 | 2005-06-30 | Ajinomoto Co Inc | ジペプチドの製造方法 |
| US20070190602A1 (en) * | 2005-12-27 | 2007-08-16 | Ajinomoto Co., Inc | Mutant protein having the peptide-synthesizing activity |
-
2003
- 2003-07-25 JP JP2003201820A patent/JP2005040037A/ja active Pending
-
2004
- 2004-07-26 WO PCT/JP2004/010990 patent/WO2005010196A1/en not_active Ceased
- 2004-07-26 KR KR1020067001652A patent/KR100760974B1/ko not_active Expired - Fee Related
- 2004-07-26 RU RU2006105494/13A patent/RU2006105494A/ru not_active Application Discontinuation
- 2004-07-26 CN CNB2004800213286A patent/CN100385012C/zh not_active Expired - Fee Related
- 2004-07-26 EP EP04748149A patent/EP1658375A4/en not_active Withdrawn
-
2006
- 2006-01-12 US US11/330,076 patent/US8084227B2/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN100385012C (zh) | 2008-04-30 |
| WO2005010196A1 (en) | 2005-02-03 |
| RU2006105494A (ru) | 2006-07-10 |
| EP1658375A4 (en) | 2009-03-18 |
| CN1826413A (zh) | 2006-08-30 |
| US8084227B2 (en) | 2011-12-27 |
| EP1658375A1 (en) | 2006-05-24 |
| US20060177893A1 (en) | 2006-08-10 |
| KR20060036470A (ko) | 2006-04-28 |
| KR100760974B1 (ko) | 2007-10-04 |
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