JP2004538228A5 - - Google Patents
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- Publication number
- JP2004538228A5 JP2004538228A5 JP2003506800A JP2003506800A JP2004538228A5 JP 2004538228 A5 JP2004538228 A5 JP 2004538228A5 JP 2003506800 A JP2003506800 A JP 2003506800A JP 2003506800 A JP2003506800 A JP 2003506800A JP 2004538228 A5 JP2004538228 A5 JP 2004538228A5
- Authority
- JP
- Japan
- Prior art keywords
- crystal
- rod
- crystals
- apatite
- dispersion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000013078 crystal Substances 0.000 claims 39
- 229910052586 apatite Inorganic materials 0.000 claims 17
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 claims 17
- 238000000034 method Methods 0.000 claims 12
- 239000006185 dispersion Substances 0.000 claims 11
- 239000000203 mixture Substances 0.000 claims 11
- -1 hydroxide ions Chemical class 0.000 claims 4
- KRHYYFGTRYWZRS-UHFFFAOYSA-M Fluoride anion Chemical compound [F-] KRHYYFGTRYWZRS-UHFFFAOYSA-M 0.000 claims 3
- 210000000988 bone and bone Anatomy 0.000 claims 3
- 239000011575 calcium Substances 0.000 claims 3
- 150000001875 compounds Chemical class 0.000 claims 3
- 229910052587 fluorapatite Inorganic materials 0.000 claims 3
- 238000009472 formulation Methods 0.000 claims 3
- 229910052588 hydroxylapatite Inorganic materials 0.000 claims 3
- 239000007788 liquid Substances 0.000 claims 3
- XYJRXVWERLGGKC-UHFFFAOYSA-D pentacalcium;hydroxide;triphosphate Chemical compound [OH-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O XYJRXVWERLGGKC-UHFFFAOYSA-D 0.000 claims 3
- 239000007858 starting material Substances 0.000 claims 3
- NBIIXXVUZAFLBC-UHFFFAOYSA-N Phosphoric acid Chemical compound OP(O)(O)=O NBIIXXVUZAFLBC-UHFFFAOYSA-N 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-M hydroxide Chemical compound [OH-] XLYOFNOQVPJJNP-UHFFFAOYSA-M 0.000 claims 2
- 150000002500 ions Chemical class 0.000 claims 2
- NROKBHXJSPEDAR-UHFFFAOYSA-M potassium fluoride Chemical compound [F-].[K+] NROKBHXJSPEDAR-UHFFFAOYSA-M 0.000 claims 2
- PUZPDOWCWNUUKD-UHFFFAOYSA-M sodium fluoride Chemical compound [F-].[Na+] PUZPDOWCWNUUKD-UHFFFAOYSA-M 0.000 claims 2
- 238000001694 spray drying Methods 0.000 claims 2
- 239000000606 toothpaste Substances 0.000 claims 2
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims 2
- DDFHBQSCUXNBSA-UHFFFAOYSA-N 5-(5-carboxythiophen-2-yl)thiophene-2-carboxylic acid Chemical compound S1C(C(=O)O)=CC=C1C1=CC=C(C(O)=O)S1 DDFHBQSCUXNBSA-UHFFFAOYSA-N 0.000 claims 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O Ammonium Chemical compound [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 claims 1
- BHPQYMZQTOCNFJ-UHFFFAOYSA-N Calcium cation Chemical compound [Ca+2] BHPQYMZQTOCNFJ-UHFFFAOYSA-N 0.000 claims 1
- NPYPAHLBTDXSSS-UHFFFAOYSA-N Potassium ion Chemical compound [K+] NPYPAHLBTDXSSS-UHFFFAOYSA-N 0.000 claims 1
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 claims 1
- 229910000147 aluminium phosphate Inorganic materials 0.000 claims 1
- WUKWITHWXAAZEY-UHFFFAOYSA-L calcium difluoride Chemical compound [F-].[F-].[Ca+2] WUKWITHWXAAZEY-UHFFFAOYSA-L 0.000 claims 1
- AXCZMVOFGPJBDE-UHFFFAOYSA-L calcium dihydroxide Chemical compound [OH-].[OH-].[Ca+2] AXCZMVOFGPJBDE-UHFFFAOYSA-L 0.000 claims 1
- 229910001634 calcium fluoride Inorganic materials 0.000 claims 1
- 239000000920 calcium hydroxide Substances 0.000 claims 1
- 229910001861 calcium hydroxide Inorganic materials 0.000 claims 1
- 229910001424 calcium ion Inorganic materials 0.000 claims 1
- 150000001768 cations Chemical class 0.000 claims 1
- 235000015218 chewing gum Nutrition 0.000 claims 1
- 239000011248 coating agent Substances 0.000 claims 1
- 238000000576 coating method Methods 0.000 claims 1
- 230000007547 defect Effects 0.000 claims 1
- 239000007943 implant Substances 0.000 claims 1
- 239000002324 mouth wash Substances 0.000 claims 1
- 239000011698 potassium fluoride Substances 0.000 claims 1
- 235000003270 potassium fluoride Nutrition 0.000 claims 1
- 229910001414 potassium ion Inorganic materials 0.000 claims 1
- 239000011775 sodium fluoride Substances 0.000 claims 1
- 235000013024 sodium fluoride Nutrition 0.000 claims 1
- 229910001415 sodium ion Inorganic materials 0.000 claims 1
- 239000007787 solid Substances 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE10130121A DE10130121A1 (de) | 2001-06-22 | 2001-06-22 | Stäbchenförmige Apatitkristalle mit einem bestimmten Länge-zu-Breite-Verhältnis |
| DE10133449A DE10133449A1 (de) | 2001-07-10 | 2001-07-10 | Stäbchenförmige Apatitkristalle mit einem bestimmten Länge-zu-Breite-Verhältnis |
| PCT/EP2002/006867 WO2003000588A1 (de) | 2001-06-22 | 2002-06-20 | Stäbchenförmige apatitkristalle mit einem bestimmten länge-zu-breite-verhältnis |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004538228A JP2004538228A (ja) | 2004-12-24 |
| JP2004538228A5 true JP2004538228A5 (https=) | 2005-09-29 |
Family
ID=26009565
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2003506800A Pending JP2004538228A (ja) | 2001-06-22 | 2002-06-20 | 特定の長さ幅比を有する棒状アパタイト結晶 |
Country Status (6)
| Country | Link |
|---|---|
| US (3) | US20040171471A1 (https=) |
| EP (1) | EP1401762A1 (https=) |
| JP (1) | JP2004538228A (https=) |
| CN (1) | CN1250449C (https=) |
| CA (1) | CA2451554A1 (https=) |
| WO (1) | WO2003000588A1 (https=) |
Families Citing this family (22)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2006058120A1 (en) | 2004-11-22 | 2006-06-01 | Vertex Pharmaceuticals Incorporated | Bicyclic inhibitors or rho kinase |
| WO2006083418A2 (en) | 2005-01-04 | 2006-08-10 | Rutgers, The State University | Hydroxyapatite with controllable size and morphology |
| EP1762215A1 (en) * | 2005-09-13 | 2007-03-14 | Unilever N.V. | Oral care composition |
| GB0524803D0 (en) * | 2005-12-05 | 2006-01-11 | Glaxo Group Ltd | Novel compositions |
| CN101489925B (zh) * | 2006-05-30 | 2013-07-10 | 科斯威尔股份有限公司 | 用碳酸根置换的羟磷灰石的生物活性纳米粒子及其制备方法和包含其的组合物 |
| ITFI20060139A1 (it) * | 2006-06-08 | 2007-12-09 | Colorobbia Italia | Idrossiapatite nanometrica, sue sospensioni preparazione ed uso. |
| FR2906331B1 (fr) * | 2006-09-26 | 2009-07-10 | Antonov Automotive Europ | "dispositif de transmission a rapports multiples compact" |
| ATE512593T1 (de) * | 2006-09-29 | 2011-07-15 | Gumlink As | Hydroxyapatithaltiger kaugummi |
| JP5458230B2 (ja) * | 2007-08-30 | 2014-04-02 | ＨＯＹＡ Ｔｅｃｈｎｏｓｕｒｇｉｃａｌ株式会社 | フッ素アパタイトの製造方法、フッ素アパタイトおよび吸着装置 |
| JP2013508262A (ja) | 2009-10-26 | 2013-03-07 | ラトガース，ザ ステート ユニバーシティ オブ ニュー ジャージー | 制御可能なサイズおよび形態を有するハイドロキシアパタイト |
| US8765168B2 (en) | 2009-11-06 | 2014-07-01 | The Regents Of The University Of Michigan | Compositions of a fluorapatite and methods of use |
| US8357732B2 (en) * | 2010-03-14 | 2013-01-22 | Mehdi Sadat-Shojai | Method for production of biocompatible nanoparticles containing dental adhesive |
| US8715625B1 (en) | 2010-05-10 | 2014-05-06 | The Clorox Company | Natural oral care compositions |
| US9896729B2 (en) | 2011-08-31 | 2018-02-20 | The University Of Manchester | Method for diagnosing a neurodegenerative disease |
| CN102805879B (zh) * | 2012-07-20 | 2014-09-24 | 陈卓凡 | 生物源性氟化羟基磷灰石骨替代材料的制备方法 |
| EP2853622B1 (en) * | 2013-09-30 | 2016-01-13 | Universidade de Vigo | Method of obtention of faceted fluorapatite nanocrystals |
| US10130560B2 (en) * | 2014-03-20 | 2018-11-20 | The Regents Of The University Of Michigan | Bioactive “smart” dental composite materials |
| KR101643336B1 (ko) * | 2014-10-14 | 2016-07-27 | 서울대학교산학협력단 | 하전된 격자결함 함유형 다중이온 동시치환 인회석 세라믹스 및 그 제조방법 |
| US10537658B2 (en) | 2017-03-28 | 2020-01-21 | DePuy Synthes Products, Inc. | Orthopedic implant having a crystalline gallium-containing hydroxyapatite coating and methods for making the same |
| US10537661B2 (en) | 2017-03-28 | 2020-01-21 | DePuy Synthes Products, Inc. | Orthopedic implant having a crystalline calcium phosphate coating and methods for making the same |
| RU2652193C1 (ru) * | 2017-04-19 | 2018-04-25 | Федеральное государственное бюджетное учреждение науки Институт химии твердого тела Уральского отделения Российской академии наук | Способ получения суспензии апатита |
| DE102019109143A1 (de) | 2019-04-08 | 2020-10-08 | Chemische Fabrik Budenheim Kg | Hydroxylapatit-Pulver und Verfahren zu dessen Herstellung |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5645814A (en) * | 1979-09-25 | 1981-04-25 | Kureha Chem Ind Co Ltd | Hydroxyapatite, its ceramic material and its manufacture |
| JPH0624964B2 (ja) * | 1985-09-23 | 1994-04-06 | 東燃株式会社 | リン酸カルシウム系ヒドロキシアパタイト及びその製造方法 |
| RU2122520C1 (ru) | 1996-10-31 | 1998-11-27 | Акционерное общество закрытого типа "ОСТИМ" | Способ получения суспензии гидроксиапатита |
| US5858318A (en) * | 1996-11-27 | 1999-01-12 | Luo; Ping | Methods of synthesizing hydroxyapatite powders and bulk materials |
| US6013591A (en) * | 1997-01-16 | 2000-01-11 | Massachusetts Institute Of Technology | Nanocrystalline apatites and composites, prostheses incorporating them, and method for their production |
| DE19858662A1 (de) | 1998-12-18 | 2000-06-21 | Henkel Kgaa | Feinteilige Suspensionen schwerlöslicher Calciumsalze und deren Verwendung in Zahnpflegemitteln |
| DE19930335A1 (de) | 1999-07-02 | 2001-01-18 | Henkel Kgaa | Kompositmaterialien aus Calciumverbindungen und Proteinkomponenten |
| DE19953771C1 (de) * | 1999-11-09 | 2001-06-13 | Coripharm Medizinprodukte Gmbh | Resorbierbares Knochen-Implantatmaterial sowie Verfahren zur Herstellung desselben |
| DE10027946A1 (de) * | 2000-06-08 | 2001-12-13 | Wolfgang Wiedemann | Keramisches Material für Dentalanwendungen sowie Verfahren zu dessen Herstellung und Verwendung eines Ausgangsstoffs des Herstellungsverfahrens für Dentalanwendungen |
| DE60026038T2 (de) * | 2000-07-03 | 2006-10-26 | Zakrytoe Aktsionernoe Obschestvo Ostim | Verfahren zur herstellung von nanodimentioniertem kristallinem hydroxyapatit |
| US6478825B1 (en) * | 2001-11-28 | 2002-11-12 | Osteotech, Inc. | Implant, method of making same and use of the implant for the treatment of bone defects |
-
2002
- 2002-06-20 US US10/480,809 patent/US20040171471A1/en not_active Abandoned
- 2002-06-20 CN CNB028124537A patent/CN1250449C/zh not_active Expired - Fee Related
- 2002-06-20 JP JP2003506800A patent/JP2004538228A/ja active Pending
- 2002-06-20 WO PCT/EP2002/006867 patent/WO2003000588A1/de not_active Ceased
- 2002-06-20 EP EP02745399A patent/EP1401762A1/de not_active Withdrawn
- 2002-06-20 CA CA002451554A patent/CA2451554A1/en not_active Abandoned
-
2005
- 2005-06-30 US US11/169,681 patent/US7153482B2/en not_active Expired - Fee Related
-
2006
- 2006-11-07 US US11/557,291 patent/US7320728B2/en not_active Expired - Fee Related
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