JP2004537517A - ｃ−ｍｙｃアンチセンスオリゴマーを使用した、癌を処置するための併用アプローチ - Google Patents
ｃ−ｍｙｃアンチセンスオリゴマーを使用した、癌を処置するための併用アプローチ Download PDFInfo
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- JP2004537517A JP2004537517A JP2002589500A JP2002589500A JP2004537517A JP 2004537517 A JP2004537517 A JP 2004537517A JP 2002589500 A JP2002589500 A JP 2002589500A JP 2002589500 A JP2002589500 A JP 2002589500A JP 2004537517 A JP2004537517 A JP 2004537517A
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Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009519242A (ja) * | 2005-12-01 | 2009-05-14 | プロネイ・セラピューティクス・インコーポレイテッド | 癌治療法およびそれに用いる医薬組成物 |
| JP2010505741A (ja) * | 2006-05-10 | 2010-02-25 | エイブイアイ バイオファーマ， インコーポレイテッド | カチオン性のサブユニット間結合を有するオリゴヌクレオチドアナログ |
| US9249243B2 (en) | 2005-07-13 | 2016-02-02 | Sarepta Therapeutics, Inc. | Antibacterial antisense oligonucleotide and method |
| US9278987B2 (en) | 2011-11-18 | 2016-03-08 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| US9469664B2 (en) | 2010-05-28 | 2016-10-18 | Sarepta Therapeutics, Inc. | Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups |
| US10017763B2 (en) | 2010-09-03 | 2018-07-10 | Sarepta Therapeutics, Inc. | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| US11020417B2 (en) | 2015-06-04 | 2021-06-01 | Sarepta Therapeutics, Inc | Methods and compounds for treatment of lymphocyte-related diseases and conditions |
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| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7640582B2 (en) | 2003-04-16 | 2009-12-29 | Silicon Graphics International | Clustered filesystem for mix of trusted and untrusted nodes |
| EP2351844B1 (en) * | 2003-04-29 | 2014-06-11 | Sarepta Therapeutics, Inc. | Compositions for enhancing transport and antisense efficacy of nucleic acid analog into cells |
| US20050288246A1 (en) * | 2004-05-24 | 2005-12-29 | Iversen Patrick L | Peptide conjugated, inosine-substituted antisense oligomer compound and method |
| US8815599B2 (en) | 2004-06-01 | 2014-08-26 | Pronai Therapeutics, Inc. | Methods and compositions for the inhibition of gene expression |
| WO2006058038A2 (en) * | 2004-11-22 | 2006-06-01 | The Research Foundation Of State University Of New York At Buffalo | In vitro and in vivo silencing of human c-myc oncogene expression by poly-dnp-rna |
| JP5122474B2 (ja) | 2005-12-01 | 2013-01-16 | プロネイ・セラピューティクス・インコーポレイテッド | 両性リポソーム製剤 |
| WO2007065017A2 (en) * | 2005-12-01 | 2007-06-07 | Pronai Therapeutics, Inc. | Oligonucleotide cationic liposomal delivery system |
| US20070270371A1 (en) * | 2006-03-31 | 2007-11-22 | Brown Bob D | Dosing and scheduling of oligomers |
| JP5864100B2 (ja) * | 2007-06-29 | 2016-02-17 | サレプタ セラピューティクス インコーポレイテッド | 組織特異的ペプチドコンジュゲートおよび方法 |
| US20100016215A1 (en) | 2007-06-29 | 2010-01-21 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| US20110269665A1 (en) | 2009-06-26 | 2011-11-03 | Avi Biopharma, Inc. | Compound and method for treating myotonic dystrophy |
| CN101624596B (zh) * | 2009-08-12 | 2011-01-26 | 广州金琪基因技术研究发展中心 | 一种靶向c-myc癌基因的外指引序列 |
| US9161948B2 (en) | 2011-05-05 | 2015-10-20 | Sarepta Therapeutics, Inc. | Peptide oligonucleotide conjugates |
| ITMI20120275A1 (it) * | 2012-02-24 | 2013-08-25 | Biogenera Societa A Responsabilita Limitata | Oligonucleotidi per la modulazione dell'espressione genica e loro usi |
| KR102192591B1 (ko) * | 2013-09-09 | 2020-12-18 | 삼성전자주식회사 | c-Met 저해제 및 c-Myc 저해제를 포함하는 병용 투여용 약학 조성물 |
| WO2016048054A2 (ko) * | 2014-09-24 | 2016-03-31 | 삼성전자 주식회사 | 데이터 통신 보안을 위한 방법, 장치 및 시스템 |
| MD3554553T2 (ro) | 2016-12-19 | 2022-10-31 | Sarepta Therapeutics Inc | Conjugați de oligomeri de omitere a exonului, pentru distrofie musculară |
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| US12378267B2 (en) | 2021-06-17 | 2025-08-05 | Entrada Therapeutics, Inc. | Synthesis of FMOC-protected morpholino monomers and oligomers |
| WO2023205451A1 (en) | 2022-04-22 | 2023-10-26 | Entrada Therapeutics, Inc. | Cyclic peptides for delivering therapeutics |
| KR20250155076A (ko) * | 2023-02-14 | 2025-10-29 | 스톡 테라퓨틱스, 인크. | 안티센스 올리고머 제형 |
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| US4515781A (en) * | 1983-02-23 | 1985-05-07 | The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services | 2',5'-Riboadenylate-morpholinoadenylate nucleotides |
| US6544755B1 (en) * | 1992-08-26 | 2003-04-08 | Ribozyme Pharmaceuticals, Inc. | Method and reagent for treatment of diseases by expression of the c-Myc gene |
| CA2153158A1 (en) * | 1993-01-07 | 1994-07-21 | Andrew Zalewski | Antisense inhibition of c-myc to modulate the proliferation of smooth muscle cells |
| EP0932698A1 (en) * | 1996-03-26 | 1999-08-04 | Lynx Therapeutics, Inc. | Oligonucleotide treatments and compositions for human melanoma |
| JP2003533986A (ja) * | 2000-05-04 | 2003-11-18 | エイブイアイ バイオファーマ， インコーポレイテッド | スプライス領域アンチセンス組成物および方法 |
-
2002
- 2002-05-17 CA CA002447052A patent/CA2447052A1/en not_active Abandoned
- 2002-05-17 KR KR10-2003-7014985A patent/KR20040004629A/ko not_active Ceased
- 2002-05-17 WO PCT/US2002/015842 patent/WO2002092617A1/en not_active Ceased
- 2002-05-17 EP EP02769769A patent/EP1399462A4/en not_active Withdrawn
- 2002-05-17 JP JP2002589500A patent/JP2004537517A/ja active Pending
- 2002-05-17 CN CNA028100719A patent/CN1509292A/zh active Pending
- 2002-05-17 US US10/151,008 patent/US20030087861A1/en not_active Abandoned
- 2002-05-17 NZ NZ530101A patent/NZ530101A/en unknown
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| US9249243B2 (en) | 2005-07-13 | 2016-02-02 | Sarepta Therapeutics, Inc. | Antibacterial antisense oligonucleotide and method |
| JP2009519242A (ja) * | 2005-12-01 | 2009-05-14 | プロネイ・セラピューティクス・インコーポレイテッド | 癌治療法およびそれに用いる医薬組成物 |
| JP2010505741A (ja) * | 2006-05-10 | 2010-02-25 | エイブイアイ バイオファーマ， インコーポレイテッド | カチオン性のサブユニット間結合を有するオリゴヌクレオチドアナログ |
| US10760078B2 (en) | 2010-05-28 | 2020-09-01 | Sarepta Therapeutics, Inc. | Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups |
| US9469664B2 (en) | 2010-05-28 | 2016-10-18 | Sarepta Therapeutics, Inc. | Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups |
| US10202602B2 (en) | 2010-05-28 | 2019-02-12 | Sarepta Therapeutics, Inc. | Oligonucleotide analogues having modified intersubunit linkages and/or terminal groups |
| US10017763B2 (en) | 2010-09-03 | 2018-07-10 | Sarepta Therapeutics, Inc. | dsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| US11072793B2 (en) | 2010-09-03 | 2021-07-27 | Sarepta Therapeutics, Inc. | DsRNA molecules comprising oligonucleotide analogs having modified intersubunit linkages and/or terminal groups |
| US9790499B2 (en) | 2011-11-18 | 2017-10-17 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| US10344281B2 (en) | 2011-11-18 | 2019-07-09 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| US9278987B2 (en) | 2011-11-18 | 2016-03-08 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| US11208655B2 (en) | 2011-11-18 | 2021-12-28 | Sarepta Therapeutics, Inc. | Functionally-modified oligonucleotides and subunits thereof |
| US11020417B2 (en) | 2015-06-04 | 2021-06-01 | Sarepta Therapeutics, Inc | Methods and compounds for treatment of lymphocyte-related diseases and conditions |
Also Published As
| Publication number | Publication date |
|---|---|
| EP1399462A4 (en) | 2008-03-05 |
| WO2002092617A1 (en) | 2002-11-21 |
| KR20040004629A (ko) | 2004-01-13 |
| US20030087861A1 (en) | 2003-05-08 |
| NZ530101A (en) | 2007-01-26 |
| CN1509292A (zh) | 2004-06-30 |
| CA2447052A1 (en) | 2002-11-21 |
| EP1399462A1 (en) | 2004-03-24 |
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