JP2004536783A - シグナル−1/シグナル−2二官能性ペプチド阻害剤 - Google Patents

シグナル−1/シグナル−2二官能性ペプチド阻害剤 Download PDF

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JP2004536783A
JP2004536783A JP2002552127A JP2002552127A JP2004536783A JP 2004536783 A JP2004536783 A JP 2004536783A JP 2002552127 A JP2002552127 A JP 2002552127A JP 2002552127 A JP2002552127 A JP 2002552127A JP 2004536783 A JP2004536783 A JP 2004536783A
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peptide
sequence
signal
amino acid
group
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Japanese (ja)
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JP2004536783A5 (enExample
Inventor
マーレイ,ジョセフ・エス
シャハーン,テルーナ・ジェイ
ヒュー,ヨンボ
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ユニバーシティ・オブ・カンザス
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Publication of JP2004536783A publication Critical patent/JP2004536783A/ja
Publication of JP2004536783A5 publication Critical patent/JP2004536783A5/ja
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/0005Vertebrate antigens
    • A61K39/001Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546Integrin superfamily
    • C07K14/70553Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88Lyases (4.)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/57Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Wood Science & Technology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Transplantation (AREA)
  • Epidemiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Cell Biology (AREA)
  • Mycology (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • Toxicology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
JP2002552127A 2000-12-18 2001-12-17 シグナル−1/シグナル−2二官能性ペプチド阻害剤 Pending JP2004536783A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/739,466 US7786257B2 (en) 2000-12-18 2000-12-18 Signal-1/signal-2 bifunctional peptide inhibitors
PCT/US2001/048632 WO2002050250A2 (en) 2000-12-18 2001-12-17 Signal-1/signal-2 bifunctional peptide inhibitors

Publications (2)

Publication Number Publication Date
JP2004536783A true JP2004536783A (ja) 2004-12-09
JP2004536783A5 JP2004536783A5 (enExample) 2005-06-09

Family

ID=24972431

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002552127A Pending JP2004536783A (ja) 2000-12-18 2001-12-17 シグナル−1/シグナル−2二官能性ペプチド阻害剤

Country Status (8)

Country Link
US (1) US7786257B2 (enExample)
EP (2) EP1404362B1 (enExample)
JP (1) JP2004536783A (enExample)
AT (1) ATE400293T1 (enExample)
AU (1) AU2002230911A1 (enExample)
CA (1) CA2432767A1 (enExample)
DE (1) DE60134791D1 (enExample)
WO (1) WO2002050250A2 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017061490A (ja) * 2011-10-18 2017-03-30 株式会社アモーレパシフィックAmorepacific Corporation シリンガレシノールを含むsirt−1活性化剤

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8188218B2 (en) 2006-10-27 2012-05-29 University Of Kansas Bi-functional peptides for multiple sclerosis treatment and diagnosis
US8735154B2 (en) 2006-10-30 2014-05-27 The University Of Kansas Templated islet cells and small islet cell clusters for diabetes treatment
US8016856B2 (en) * 2006-11-30 2011-09-13 Cook Medical Technologies Llc Removable handle for medical device
GB0710529D0 (en) 2007-06-01 2007-07-11 Circassia Ltd Vaccine
ES2402956T3 (es) 2007-08-15 2013-05-10 Circassia Limited Péptido con formación de dímeros reducida
EP2211889B1 (en) * 2007-10-25 2014-08-20 The Scripps Research Institute Antibody-mediated disruption of quorum sensing in bacteria
DE102009040716B4 (de) * 2009-09-10 2011-07-14 Miltenyi Biotec GmbH, 51429 Verwendung von CD154 zur Identifizierung und Abtrennung von nicht-regulatorischen T-Zellen aus einem Gemisch mit regulatorischen T-Zellen
WO2011163568A1 (en) 2010-06-24 2011-12-29 University Of Kansas Conjugates comprising an n-oxime bond and associated methods
WO2013016544A2 (en) 2011-07-27 2013-01-31 University Of Kansas Templated islet cells and small islet cell clusters for diabetes treatment
US11919939B2 (en) * 2017-05-23 2024-03-05 Université De Genève Beta-2-glycoprotein 1 derived peptide and use thereof for treating antiphospholipid syndrome

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844095A (en) * 1991-06-27 1998-12-01 Bristol-Myers Squibb Company CTLA4 Ig fusion proteins
EP0576842B1 (de) * 1992-06-11 2002-10-16 MERCK PATENT GmbH Verfahren und Mittel zum Nachweis von Listerien
US5540926A (en) 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
ATE417112T1 (de) 1997-03-27 2008-12-15 Csl Ltd Steigerung der immunantwort unter verwendung von zielgerichteten molekülen
US7118751B1 (en) * 1999-10-14 2006-10-10 Trubion Pharmaceuticals, Inc. DNA vaccines encoding antigen linked to a domain that binds CD40

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017061490A (ja) * 2011-10-18 2017-03-30 株式会社アモーレパシフィックAmorepacific Corporation シリンガレシノールを含むsirt−1活性化剤

Also Published As

Publication number Publication date
EP1404362A2 (en) 2004-04-07
EP1404362A4 (en) 2005-06-01
ATE400293T1 (de) 2008-07-15
WO2002050250A2 (en) 2002-06-27
WO2002050250A3 (en) 2004-01-08
DE60134791D1 (de) 2008-08-21
EP1404362B1 (en) 2008-07-09
EP1932539A2 (en) 2008-06-18
CA2432767A1 (en) 2002-06-27
EP1932539A3 (en) 2008-10-29
US7786257B2 (en) 2010-08-31
AU2002230911A1 (en) 2002-07-01
US20050107585A1 (en) 2005-05-19

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