ATE400293T1 - Signal-1/signal-2-bifunktionelle peptidinhibitoren - Google Patents

Signal-1/signal-2-bifunktionelle peptidinhibitoren

Info

Publication number
ATE400293T1
ATE400293T1 AT01991168T AT01991168T ATE400293T1 AT E400293 T1 ATE400293 T1 AT E400293T1 AT 01991168 T AT01991168 T AT 01991168T AT 01991168 T AT01991168 T AT 01991168T AT E400293 T1 ATE400293 T1 AT E400293T1
Authority
AT
Austria
Prior art keywords
chain
signal
moiety
immune response
type
Prior art date
Application number
AT01991168T
Other languages
English (en)
Inventor
Joseph Murray
Teruna Siahaan
Yongbo Hu
Original Assignee
Univ Kansas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Univ Kansas filed Critical Univ Kansas
Application granted granted Critical
Publication of ATE400293T1 publication Critical patent/ATE400293T1/de

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/0005—Vertebrate antigens
    • A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70546—Integrin superfamily
    • C07K14/70553—Integrin beta2-subunit-containing molecules, e.g. CD11, CD18
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2821—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against ICAM molecules, e.g. CD50, CD54, CD102
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2833—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against MHC-molecules, e.g. HLA-molecules
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/88—Lyases (4.)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Biotechnology (AREA)
  • Transplantation (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Epidemiology (AREA)
  • Biomedical Technology (AREA)
  • Toxicology (AREA)
  • Mycology (AREA)
  • Cell Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT01991168T 2000-12-18 2001-12-17 Signal-1/signal-2-bifunktionelle peptidinhibitoren ATE400293T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US09/739,466 US7786257B2 (en) 2000-12-18 2000-12-18 Signal-1/signal-2 bifunctional peptide inhibitors

Publications (1)

Publication Number Publication Date
ATE400293T1 true ATE400293T1 (de) 2008-07-15

Family

ID=24972431

Family Applications (1)

Application Number Title Priority Date Filing Date
AT01991168T ATE400293T1 (de) 2000-12-18 2001-12-17 Signal-1/signal-2-bifunktionelle peptidinhibitoren

Country Status (8)

Country Link
US (1) US7786257B2 (de)
EP (2) EP1404362B1 (de)
JP (1) JP2004536783A (de)
AT (1) ATE400293T1 (de)
AU (1) AU2002230911A1 (de)
CA (1) CA2432767A1 (de)
DE (1) DE60134791D1 (de)
WO (1) WO2002050250A2 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8188218B2 (en) 2006-10-27 2012-05-29 University Of Kansas Bi-functional peptides for multiple sclerosis treatment and diagnosis
US8735154B2 (en) 2006-10-30 2014-05-27 The University Of Kansas Templated islet cells and small islet cell clusters for diabetes treatment
EP2083715B1 (de) * 2006-11-30 2013-03-13 Cook Medical Technologies LLC Entfernbarer handgriff für ein medizinprodukt
GB0710529D0 (en) * 2007-06-01 2007-07-11 Circassia Ltd Vaccine
EP2286833A3 (de) 2007-08-15 2011-09-14 Circassia Limited Peptide zur desensibilisierung gegen allergene
CN101835484B (zh) * 2007-10-25 2014-07-16 斯克利普斯研究院 细菌群体感应的抗体介导性破坏
DE102009040716B4 (de) * 2009-09-10 2011-07-14 Miltenyi Biotec GmbH, 51429 Verwendung von CD154 zur Identifizierung und Abtrennung von nicht-regulatorischen T-Zellen aus einem Gemisch mit regulatorischen T-Zellen
EP2585108A4 (de) 2010-06-24 2016-04-13 Univ Kansas Konjugate mit einem n-oxim-bindung und zugehörige verfahren
CA2842695C (en) 2011-07-27 2021-01-12 University Of Kansas Method of evaluating a xenobiotic for biological activity using one or more divots
CN105708834A (zh) * 2011-10-18 2016-06-29 株式会社爱茉莉太平洋 包含丁香脂素的sirt1活化剂
EP3631449A1 (de) * 2017-05-23 2020-04-08 Université de Genève Peptid aus beta-2-glycoprotein 1 und dessen verwendung zur behandlung des antiphospholipidsyndroms

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5844095A (en) * 1991-06-27 1998-12-01 Bristol-Myers Squibb Company CTLA4 Ig fusion proteins
DE59310308D1 (de) * 1992-06-11 2002-11-21 Merck Patent Gmbh Verfahren und Mittel zum Nachweis von Listerien
US5540926A (en) * 1992-09-04 1996-07-30 Bristol-Myers Squibb Company Soluble and its use in B cell stimulation
NZ500151A (en) 1997-03-27 2001-01-26 Univ Melbourne A general method for attaching DNA molecule comprising non-antibody target molecule (eg. CTLA-4 or L-selectin), antigen or epitope sequence, and optionally a polypeptide sequence
US7118751B1 (en) * 1999-10-14 2006-10-10 Trubion Pharmaceuticals, Inc. DNA vaccines encoding antigen linked to a domain that binds CD40

Also Published As

Publication number Publication date
DE60134791D1 (de) 2008-08-21
EP1932539A3 (de) 2008-10-29
EP1404362B1 (de) 2008-07-09
EP1404362A2 (de) 2004-04-07
EP1404362A4 (de) 2005-06-01
AU2002230911A1 (en) 2002-07-01
EP1932539A2 (de) 2008-06-18
JP2004536783A (ja) 2004-12-09
CA2432767A1 (en) 2002-06-27
US7786257B2 (en) 2010-08-31
WO2002050250A3 (en) 2004-01-08
WO2002050250A2 (en) 2002-06-27
US20050107585A1 (en) 2005-05-19

Similar Documents

Publication Publication Date Title
ATE400293T1 (de) Signal-1/signal-2-bifunktionelle peptidinhibitoren
SE8703012D0 (sv) Retainer for glove
SE8702550D0 (sv) Cysteinproteashemmare
DE60009511D1 (de) Nematizide trifluorbutene
PT891428E (pt) Sub-unidade catalitica fosfatidilinositol 3-cinase p110 delta
DE60327649D1 (de) Markierte nukleotide
DE60210022D1 (de) Verbesserte Anordnung von Sensorelementen für einen Fingerabdrucksensor
ATE388230T1 (de) Neisseria meningitidis antigene und zusammenstellungen
BE905918A (fr) Maillon pour une chaine de recueillement de produits.
ATE67860T1 (de) Geraet zur fliess-injektionsanalyse.
DK524388D0 (da) Forbraending af kul med et fluidiseret forbraendingsleje
DE68927630D1 (de) Analoge von Peptrolsubstraten
ATE108801T1 (de) Antikoagulierende peptid-alkohole.
FI904852A0 (fi) Antikoagulantpeptider.
DK431189D0 (da) Peptidaseinhibitorer
DE59000793D1 (de) Heizkessel zum verbrennen fluessiger oder gasfoermiger brennstoffe.
DK614489A (da) Peptidderivater
DE50102625D1 (de) Verbindungen zur Bestimmung der Aktivität von Phospholipase A2
BRPI0416201A (pt) métodos para purificação de toxina coqueluche e peptìdios neles utilizáveis
DE69233666D1 (de) Verzweigte Peptide zum Nachweis von Antikörpern
ATE280229T1 (de) Enterotoxine von shigella flexneri 2a
DE59903388D1 (de) Schubrostanordnung für einen Festbrennstoff-Kessel o. dgl.
DK1041461T3 (da) Armbåndsur
NO179010C (no) Antistoffer mot höyt konserverte aminosyresekvenser fra immunogene forbindelser og anvendelse derav i immunoanalyser
EP1180525A4 (de) Hemmerprotein der transkriptionsaktivierung

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties