JP2004535382A5 - - Google Patents

Download PDF

Info

Publication number
JP2004535382A5
JP2004535382A5 JP2002581694A JP2002581694A JP2004535382A5 JP 2004535382 A5 JP2004535382 A5 JP 2004535382A5 JP 2002581694 A JP2002581694 A JP 2002581694A JP 2002581694 A JP2002581694 A JP 2002581694A JP 2004535382 A5 JP2004535382 A5 JP 2004535382A5
Authority
JP
Japan
Prior art keywords
mobility
polymer
sequence
nucleobase polymer
group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002581694A
Other languages
English (en)
Japanese (ja)
Other versions
JP4452445B2 (ja
JP2004535382A (ja
Filing date
Publication date
Priority claimed from US09/836,704 external-priority patent/US6743905B2/en
Application filed filed Critical
Publication of JP2004535382A publication Critical patent/JP2004535382A/ja
Publication of JP2004535382A5 publication Critical patent/JP2004535382A5/ja
Application granted granted Critical
Publication of JP4452445B2 publication Critical patent/JP4452445B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

JP2002581694A 2001-04-16 2002-04-15 移動度改変ヌクレオ塩基ポリマーおよび同一物を使用する方法 Expired - Fee Related JP4452445B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/836,704 US6743905B2 (en) 2001-04-16 2001-04-16 Mobility-modified nucleobase polymers and methods of using same
PCT/US2002/011824 WO2002083954A1 (en) 2001-04-16 2002-04-15 Mobility-modified nucleobase polymers and methods of using same

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009177108A Division JP2009240332A (ja) 2001-04-16 2009-07-29 移動度改変ヌクレオ塩基ポリマーおよび同一物を使用する方法

Publications (3)

Publication Number Publication Date
JP2004535382A JP2004535382A (ja) 2004-11-25
JP2004535382A5 true JP2004535382A5 (cg-RX-API-DMAC7.html) 2006-01-05
JP4452445B2 JP4452445B2 (ja) 2010-04-21

Family

ID=25272541

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002581694A Expired - Fee Related JP4452445B2 (ja) 2001-04-16 2002-04-15 移動度改変ヌクレオ塩基ポリマーおよび同一物を使用する方法
JP2009177108A Withdrawn JP2009240332A (ja) 2001-04-16 2009-07-29 移動度改変ヌクレオ塩基ポリマーおよび同一物を使用する方法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009177108A Withdrawn JP2009240332A (ja) 2001-04-16 2009-07-29 移動度改変ヌクレオ塩基ポリマーおよび同一物を使用する方法

Country Status (7)

Country Link
US (4) US6743905B2 (cg-RX-API-DMAC7.html)
EP (1) EP1379698B1 (cg-RX-API-DMAC7.html)
JP (2) JP4452445B2 (cg-RX-API-DMAC7.html)
AT (1) ATE440966T1 (cg-RX-API-DMAC7.html)
CA (1) CA2443122A1 (cg-RX-API-DMAC7.html)
DE (1) DE60233477D1 (cg-RX-API-DMAC7.html)
WO (1) WO2002083954A1 (cg-RX-API-DMAC7.html)

Families Citing this family (89)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7537938B2 (en) 2000-04-28 2009-05-26 Monogram Biosciences, Inc. Biomarker detection in circulating cells
US20030207300A1 (en) * 2000-04-28 2003-11-06 Matray Tracy J. Multiplex analytical platform using molecular tags
US6743905B2 (en) * 2001-04-16 2004-06-01 Applera Corporation Mobility-modified nucleobase polymers and methods of using same
JP2005505749A (ja) 2001-05-21 2005-02-24 アクララ バイオサイエンシーズ， インコーポレイテッド タンパク質を分析するための方法および組成物
US20050164205A1 (en) * 2002-11-19 2005-07-28 Singulex, Inc. Charge and mass tags for detection and analysis
US20040126765A1 (en) * 2002-12-27 2004-07-01 Adams Craig W. Method and compositions for sequencing nucleic acid molecules
WO2005001129A2 (en) * 2003-06-06 2005-01-06 Applera Corporation Mobility cassettes
WO2005066359A1 (en) * 2003-12-31 2005-07-21 Applera Corporation Multiplex protease profiling
US20080103053A1 (en) * 2005-11-22 2008-05-01 Helicos Biosciences Corporation Methods and compositions for sequencing a nucleic acid
WO2007100574A2 (en) * 2006-02-22 2007-09-07 Tyco Healthcare Group Lp Biodegradable phosphoester polyamines
EP1994182B1 (en) * 2006-03-15 2019-05-29 Siemens Healthcare Diagnostics Inc. Degenerate nucleobase analogs
CA2653841C (en) * 2006-06-01 2016-07-19 Trilink Biotechnologies Chemically modified oligonucleotide primers for nucleic acid amplification
EP3543357A1 (en) 2007-05-08 2019-09-25 Trustees of Boston University Chemical functionalization of solid-state nanopores and nanopore arrays and applications thereof
US8097712B2 (en) 2007-11-07 2012-01-17 Beelogics Inc. Compositions for conferring tolerance to viral disease in social insects, and the use thereof
WO2010046829A1 (en) * 2008-10-20 2010-04-29 Koninklijke Philips Electronics N.V. Separation free ser(r)s assay
WO2011027966A2 (en) * 2009-09-03 2011-03-10 Seegene, Inc. Td probe and its uses
AU2010301128B2 (en) 2009-09-30 2014-09-18 Quantapore, Inc. Ultrafast sequencing of biological polymers using a labeled nanopore
US8962584B2 (en) 2009-10-14 2015-02-24 Yissum Research Development Company Of The Hebrew University Of Jerusalem, Ltd. Compositions for controlling Varroa mites in bees
BR112012022570A2 (pt) 2010-03-08 2015-10-06 Monsato Technology Llc moléculas de polinucleotídeo para regulação de gene em plantas.
WO2012080836A2 (en) 2010-12-13 2012-06-21 Marek Kwiatkowski Functionalized polymers
EP2755466A4 (en) 2011-09-13 2015-04-15 Monsanto Technology Llc METHOD AND COMPOSITIONS FOR WEED CONTROL
UA116092C2 (uk) 2011-09-13 2018-02-12 Монсанто Текнолоджи Ллс Спосіб та композиція для боротьби з бур'янами (варіанти)
US10760086B2 (en) 2011-09-13 2020-09-01 Monsanto Technology Llc Methods and compositions for weed control
BR112014005963A2 (pt) 2011-09-13 2020-12-08 Monsanto Technology Llc métodos de controle de planta, de redução de expressão de um gene als em uma planta, de identificação de polinucleotídeos úteis na modulação de expressão do gene als, de fazer um polinucleotídeo, composições compreendendo um polinucleotídeo e um agente de transferência ou um herbicida, cassete de expressão microbiana, bem como molécula de polinucleotídeo
US10829828B2 (en) 2011-09-13 2020-11-10 Monsanto Technology Llc Methods and compositions for weed control
US10806146B2 (en) 2011-09-13 2020-10-20 Monsanto Technology Llc Methods and compositions for weed control
WO2013040049A1 (en) 2011-09-13 2013-03-21 Monsanto Technology Llc Methods and compositions for weed control
AU2012308753B2 (en) 2011-09-13 2018-05-17 Monsanto Technology Llc Methods and compositions for weed control
US9840715B1 (en) 2011-09-13 2017-12-12 Monsanto Technology Llc Methods and compositions for delaying senescence and improving disease tolerance and yield in plants
AU2012308818B2 (en) 2011-09-13 2018-06-21 Monsanto Technology Llc Methods and compositions for weed control
BR112014005958A2 (pt) 2011-09-13 2020-10-13 Monsanto Technology Llc métodos e composições químicas agrícolas para controle de planta, método de redução de expressão de um gene accase em uma planta, cassete de expressão microbiana, método para fazer um polinucleotídeo, método de identificação de polinucleotídeos úteis na modulação de expressão do gene accase e composição herbicida
AU2012308659B2 (en) 2011-09-13 2017-05-04 Monsanto Technology Llc Methods and compositions for weed control
US9920326B1 (en) 2011-09-14 2018-03-20 Monsanto Technology Llc Methods and compositions for increasing invertase activity in plants
WO2013126034A1 (en) * 2012-02-22 2013-08-29 Chemgenes Corporation Synthesis of high purity dmt-c3-disulfide phosphoramidite
WO2013175480A1 (en) 2012-05-24 2013-11-28 A.B. Seeds Ltd. Compositions and methods for silencing gene expression
WO2013186632A2 (en) * 2012-06-12 2013-12-19 Quiapeg Ab Conjugates of biologically active molecules to functionalized polymers
CN104755632B (zh) 2012-09-06 2017-10-03 生命技术公司 多重y‑str分析
PT3622810T (pt) 2012-09-24 2024-04-03 Seminis Vegetable Seeds Inc Métodos e composições para prolongar a vida útil de produtos vegetais
BR112015008706A2 (pt) 2012-10-18 2018-02-06 Monsanto Technology Llc métodos e composições para controle de praga de plantas
US9651539B2 (en) 2012-10-28 2017-05-16 Quantapore, Inc. Reducing background fluorescence in MEMS materials by low energy ion beam treatment
US10683505B2 (en) 2013-01-01 2020-06-16 Monsanto Technology Llc Methods of introducing dsRNA to plant seeds for modulating gene expression
WO2014106837A2 (en) 2013-01-01 2014-07-10 A. B. Seeds Ltd. ISOLATED dsRNA MOLECULES AND METHODS OF USING SAME FOR SILENCING TARGET MOLECULES OF INTEREST
CN105188382B (zh) 2013-01-15 2019-02-19 孟山都技术公司 用于植物害虫控制的方法和组合物
US10000767B2 (en) 2013-01-28 2018-06-19 Monsanto Technology Llc Methods and compositions for plant pest control
EP2971185A4 (en) 2013-03-13 2017-03-08 Monsanto Technology LLC Methods and compositions for weed control
CA2905104A1 (en) 2013-03-13 2014-10-09 Monsanto Technology Llc Control of lolium species by topical application of herbicidal composition comprising dsrna
US20140283211A1 (en) 2013-03-14 2014-09-18 Monsanto Technology Llc Methods and Compositions for Plant Pest Control
US10568328B2 (en) 2013-03-15 2020-02-25 Monsanto Technology Llc Methods and compositions for weed control
AU2014268322B2 (en) 2013-05-24 2019-01-24 Quantapore, Inc. Nanopore-based nucleic acid analysis with mixed FRET detection
US9850496B2 (en) 2013-07-19 2017-12-26 Monsanto Technology Llc Compositions and methods for controlling Leptinotarsa
RU2703498C2 (ru) 2013-07-19 2019-10-17 Монсанто Текнолоджи Ллс Композиции и способы борьбы с leptinotarsa
WO2015027176A1 (en) 2013-08-22 2015-02-26 Sony Corporation Water soluble fluorescent or colored dyes and methods for their use
HUE070313T2 (hu) 2013-11-04 2025-05-28 Greenlight Biosciences Inc Ízeltlábú paraziták és kártevõfertõzöttség szabályozására szolgáló készítmények és eljárások
UA119253C2 (uk) 2013-12-10 2019-05-27 Біолоджикс, Інк. Спосіб боротьби із вірусом у кліща varroa та у бджіл
AU2015206585A1 (en) 2014-01-15 2016-07-21 Monsanto Technology Llc Methods and compositions for weed control using EPSPS polynucleotides
CN110506752B (zh) 2014-04-01 2022-02-18 孟山都技术公司 用于控制虫害的组合物和方法
AU2015280252A1 (en) 2014-06-23 2017-01-12 Monsanto Technology Llc Compositions and methods for regulating gene expression via RNA interference
WO2015200539A1 (en) 2014-06-25 2015-12-30 Monsanto Technology Llc Methods and compositions for delivering nucleic acids to plant cells and regulating gene expression
US10378012B2 (en) 2014-07-29 2019-08-13 Monsanto Technology Llc Compositions and methods for controlling insect pests
AU2015330841B2 (en) 2014-10-10 2019-08-15 Quantapore, Inc. Nanopore-based polymer analysis with mutually-quenching fluorescent labels
CA2964790C (en) 2014-10-24 2023-02-21 Quantapore, Inc. Efficient optical analysis of polymers using arrays of nanostructures
CA2974101A1 (en) 2015-01-22 2016-07-28 Monsanto Technology Llc Compositions and methods for controlling leptinotarsa
EP3262055A4 (en) 2015-02-26 2018-09-05 Sony Corporation Water soluble fluorescent or colored dyes comprising conjugating groups
US10883103B2 (en) 2015-06-02 2021-01-05 Monsanto Technology Llc Compositions and methods for delivery of a polynucleotide into a plant
US10655136B2 (en) 2015-06-03 2020-05-19 Monsanto Technology Llc Methods and compositions for introducing nucleic acids into plants
US10975387B2 (en) 2016-01-26 2021-04-13 Monsanto Technology Llc Compositions and methods for controlling insect pests
CN114806218A (zh) 2016-04-01 2022-07-29 索尼公司 超亮二聚或多聚染料
AU2017248165B2 (en) 2016-04-06 2021-08-26 Sony Group Corporation Ultra bright dimeric or polymeric dyes with spacing linker groups
JP7071286B2 (ja) 2016-05-11 2022-05-18 ソニーグループ株式会社 超明色ダイマーまたはポリマー染料
US10823721B2 (en) 2016-07-05 2020-11-03 Quantapore, Inc. Optically based nanopore sequencing
US10822647B2 (en) 2016-07-12 2020-11-03 Biodynamics S.R.L. Methods for using long ssDNA polynucleotides as primers (superprimers) in PCR assays
US10465242B2 (en) 2016-07-14 2019-11-05 University Of Utah Research Foundation Multi-sequence capture system
WO2018022925A1 (en) 2016-07-29 2018-02-01 Sony Corporation Ultra bright dimeric or polymeric dyes and methods for preparation of the same
EP4011396A1 (en) 2017-03-10 2022-06-15 QuiaPEG Pharmaceuticals AB Releasable conjugates
CN111093711A (zh) 2017-10-05 2020-05-01 索尼公司 可编程的树枝状药物
JP7551056B2 (ja) 2017-10-05 2024-09-17 ソニーグループ株式会社 プログラマブルなポリマー薬物
WO2019099789A1 (en) 2017-11-16 2019-05-23 Sony Corporation Programmable polymeric drugs
CN111565756A (zh) 2018-01-12 2020-08-21 索尼公司 包含生物活性化合物的具有刚性间隔基团的聚合物
WO2019140227A1 (en) 2018-01-12 2019-07-18 Sony Corporation Phosphoalkyl ribose polymers comprising biologically active compounds
JP2021520423A (ja) 2018-03-19 2021-08-19 ソニーグループ株式会社 蛍光シグナルを増強するための二価金属の使用
JP7515786B2 (ja) 2018-03-21 2024-07-16 ソニーグループ株式会社 リンカー基を有するポリマータンデム色素
KR102854332B1 (ko) 2018-06-27 2025-09-03 소니그룹주식회사 디옥시리보오스를 포함하는 링커 군을 갖는 중합체성 염료
CN112955216A (zh) 2018-09-12 2021-06-11 奎亚培格制药公司 可释放glp-1缀合物
WO2021062176A2 (en) 2019-09-26 2021-04-01 Sony Corporation Polymeric tandem dyes with linker groups
US20230295711A1 (en) * 2020-06-30 2023-09-21 Illumina, Inc. Compositions and methods for sequencing using at least electrical characteristics
EP4251764A1 (en) * 2020-11-25 2023-10-04 Sony Group Corporation Polymer dyes
WO2022125564A1 (en) 2020-12-07 2022-06-16 Sony Group Corporation Spacing linker group design for brightness enhancement in dimeric or polymeric dyes
KR20220087091A (ko) * 2020-12-17 2022-06-24 오토텔릭바이오 주식회사 고순도 안티센스 올리고뉴클레오타이드의 제조방법
EP4074839A1 (en) * 2021-04-16 2022-10-19 Biotype GmbH Optimized oligonucleotide tx probe for a multiplexing analysis of nucleic acids and a multiplexing method

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1218721B (de) * 1960-07-20 1966-06-08 Bayer Ag Stabilisieren chlorhaltiger Polymerisate
US3172871A (en) * 1960-02-26 1965-03-09 Ch3 chj
US5470974A (en) 1985-03-15 1995-11-28 Neu-Gene Development Group Uncharged polynucleotide-binding polymers
US5185444A (en) 1985-03-15 1993-02-09 Anti-Gene Deveopment Group Uncharged morpolino-based polymers having phosphorous containing chiral intersubunit linkages
US4914210A (en) 1987-10-02 1990-04-03 Cetus Corporation Oligonucleotide functionalizing reagents
US5470967A (en) 1990-04-10 1995-11-28 The Dupont Merck Pharmaceutical Company Oligonucleotide analogs with sulfamate linkages
ATE173767T1 (de) 1992-04-03 1998-12-15 Perkin Elmer Corp Proben zusammensetzung und verfahren
US5470705A (en) 1992-04-03 1995-11-28 Applied Biosystems, Inc. Probe composition containing a binding domain and polymer chain and methods of use
US5696253A (en) 1994-06-30 1997-12-09 The Regents Of The University Of California Polynucleoside chain with 3'→5' guanidyl linkages
JP2001518054A (ja) 1995-06-07 2001-10-09 パーセプティブ バイオシステムズ，インコーポレーテッド Ｐｎａ−ｄｎａキメラと、このキメラ合成用のｐｎａシントン
DE69723473T2 (de) 1996-10-15 2004-05-27 The Liposome Co., Inc. Peptid-lipid konjugate, liposomen und liposomale arzneimittelverabreichung
US6339069B1 (en) 1996-10-15 2002-01-15 Elan Pharmaceuticalstechnologies, Inc. Peptide-lipid conjugates, liposomes and lipsomal drug delivery
EP1161563A2 (en) * 1999-03-15 2001-12-12 PE Corporation (NY) Probe/mobility modifier complexes for multiplex nucleic acid detection
US6743905B2 (en) 2001-04-16 2004-06-01 Applera Corporation Mobility-modified nucleobase polymers and methods of using same

Similar Documents

Publication Publication Date Title
JP2004535382A5 (cg-RX-API-DMAC7.html)
US6743905B2 (en) Mobility-modified nucleobase polymers and methods of using same
EP0416817B1 (en) Amplification processes
EP0742287B1 (en) Modified nucleic acid probes
JP4714320B2 (ja) アミノ基転移による固相核酸標識化
CA2239287C (en) A cascade nucleic acid amplification reaction
US8518671B2 (en) Solid support assay systems and methods utilizing non-standard bases
US20030077609A1 (en) Modified oligonucleotides and uses thereof
WO2008083261A1 (en) Systems and methods for detecting nucleic acids
JP2007506429A (ja) ポリマー核酸のハイブリダイゼーションプローブ
JP2009017882A (ja) 標的ハイブリダイゼーション検出のための、プローブおよびクランプのバイナリー組成物ならびに方法
US20080090247A1 (en) Method for detecting a structured target
JP2010521142A (ja) 遺伝子発現アッセイ
US7919611B2 (en) Nucleotide primer set and nucleotide probe for detecting genotype of N-acetyltransferase-2 (NAT2)
US6942974B2 (en) Selective elution of immobilized multiplexed primer extension products
US7462451B2 (en) Compositions for modifying nucleic acids
CA2564838A1 (en) Hybridization method
JPH10262675A (ja) オリゴヌクレオチド及び核酸の塩基配列解析法
AU2002303356A1 (en) Mobility-modified nucleobase polymers and methods of using same
HK1014561B (en) Modified nucleic acid probes