JP2004531270A5 - - Google Patents

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Publication number
JP2004531270A5
JP2004531270A5 JP2003507235A JP2003507235A JP2004531270A5 JP 2004531270 A5 JP2004531270 A5 JP 2004531270A5 JP 2003507235 A JP2003507235 A JP 2003507235A JP 2003507235 A JP2003507235 A JP 2003507235A JP 2004531270 A5 JP2004531270 A5 JP 2004531270A5
Authority
JP
Japan
Prior art keywords
monoclonal antibody
antibody
kda
antigen
protein
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2003507235A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004531270A (ja
JP4455876B2 (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2002/019646 external-priority patent/WO2003000848A2/en
Publication of JP2004531270A publication Critical patent/JP2004531270A/ja
Publication of JP2004531270A5 publication Critical patent/JP2004531270A5/ja
Application granted granted Critical
Publication of JP4455876B2 publication Critical patent/JP4455876B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2003507235A 2001-06-22 2002-06-21 肝移植細胞、アッセイ法、およびその使用法 Expired - Fee Related JP4455876B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30053501P 2001-06-22 2001-06-22
PCT/US2002/019646 WO2003000848A2 (en) 2001-06-22 2002-06-21 Liver engrafting cells, assays, and uses thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2009090608A Division JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Publications (3)

Publication Number Publication Date
JP2004531270A JP2004531270A (ja) 2004-10-14
JP2004531270A5 true JP2004531270A5 (enExample) 2006-01-05
JP4455876B2 JP4455876B2 (ja) 2010-04-21

Family

ID=23159503

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2003507235A Expired - Fee Related JP4455876B2 (ja) 2001-06-22 2002-06-21 肝移植細胞、アッセイ法、およびその使用法
JP2009090608A Withdrawn JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2009090608A Withdrawn JP2009183299A (ja) 2001-06-22 2009-04-03 肝移植細胞、アッセイ法、およびその使用法

Country Status (11)

Country Link
US (3) US7211404B2 (enExample)
EP (3) EP1406998B1 (enExample)
JP (2) JP4455876B2 (enExample)
CN (2) CN101974480A (enExample)
AT (1) ATE371018T1 (enExample)
AU (1) AU2002315392B2 (enExample)
CA (1) CA2451637C (enExample)
DE (1) DE60221987T2 (enExample)
DK (1) DK1406998T3 (enExample)
ES (1) ES2292772T3 (enExample)
WO (1) WO2003000848A2 (enExample)

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US8044259B2 (en) 2000-08-03 2011-10-25 The Regents Of The University Of Michigan Determining the capability of a test compound to affect solid tumor stem cells
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CA2528669A1 (en) * 2003-06-09 2005-01-20 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20050014217A1 (en) * 2003-07-18 2005-01-20 Cytokinetics, Inc. Predicting hepatotoxicity using cell based assays
CA2554779A1 (en) * 2004-02-03 2005-08-18 The Regents Of The University Of Michigan Compositions and methods for characterizing, regulating, diagnosing, and treating cancer
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US20060252073A1 (en) * 2005-04-18 2006-11-09 Regents Of The University Of Michigan Compositions and methods for the treatment of cancer
US20070105133A1 (en) * 2005-06-13 2007-05-10 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US20070099209A1 (en) * 2005-06-13 2007-05-03 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US7723112B2 (en) * 2005-10-31 2010-05-25 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing cancer
US7723477B2 (en) 2005-10-31 2010-05-25 Oncomed Pharmaceuticals, Inc. Compositions and methods for inhibiting Wnt-dependent solid tumor cell growth
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ATE498005T1 (de) 2005-12-21 2011-02-15 Univ Catholique Louvain Isolierte leberstammzellen
EP1998785A4 (en) * 2006-02-21 2009-06-17 Univ Michigan TREATMENT OF CANCER BY AN ANTAGONIST OF THE HEDGEHOG SIGNALING PATH
WO2008092002A2 (en) 2007-01-24 2008-07-31 The Regents Of The University Of Michigan Compositions and methods for treating and diagnosing pancreatic cancer
EP2158321B1 (en) * 2007-06-05 2021-08-04 Oregon Health & Science University Method of expanding human hepatocytes in vivo
CN102083967B (zh) * 2007-07-20 2013-05-15 塞拉提斯股份公司 经由定型内胚层(DE-hep)衍生自人胚泡衍生干细胞的新肝细胞群体
US8241898B2 (en) * 2007-12-10 2012-08-14 The Board Of Trustees Of The Leland Stanford Junior University Regenerative dot cells
WO2009111778A2 (en) * 2008-03-07 2009-09-11 University Of Pittsburgh-Of The Commonwealth System Of Higher Education Lymph nodes as a site for regeneration
TWI506037B (zh) 2008-09-26 2015-11-01 Oncomed Pharm Inc 捲曲結合劑類及彼等之用途
US20100227393A1 (en) * 2009-03-06 2010-09-09 Eric Lagasse Liver stem cells: isolation of hepatic progenitor cells from the human gall bladder
TWI535445B (zh) 2010-01-12 2016-06-01 安可美德藥物股份有限公司 Wnt拮抗劑及治療和篩選方法
US20130071365A1 (en) * 2010-02-16 2013-03-21 Kyushu University, National University Corporation Induced hepatocytes
WO2011123785A2 (en) 2010-04-01 2011-10-06 Oncomed Pharmaceuticals, Inc. Frizzled-binding agents and uses thereof
EP2911691B1 (en) 2012-10-23 2018-10-10 OncoMed Pharmaceuticals, Inc. Methods of treating neuroendocrine tumors using wnt pathway-binding agents
JP2016510411A (ja) 2013-02-04 2016-04-07 オンコメッド ファーマシューティカルズ インコーポレイテッド Wnt経路インヒビターによる処置の方法およびモニタリング
US9168300B2 (en) 2013-03-14 2015-10-27 Oncomed Pharmaceuticals, Inc. MET-binding agents and uses thereof
DK3016665T3 (da) 2013-07-05 2019-11-25 Univ Catholique Louvain Konditioneret medium fra humane voksne leverstamceller og dets anvendelse i behandlingen af leverlidelser
JP6672603B2 (ja) * 2015-03-27 2020-03-25 株式会社豊田中央研究所 物質と細胞との間の作用の評価方法
IL256342B2 (en) * 2015-06-23 2023-04-01 Jackson Lab A humanized nsg mouse model with hla-mismatched patient-derived grafts
MX2019009367A (es) * 2017-02-17 2019-10-24 Univ Pittsburgh Commonwealth Sys Higher Education Grupos linfoides asociados al tejido graso como sitios de trasplante, regeneración de tejidos, organogénesis y función para múltiples tejidos.
WO2019210279A1 (en) * 2018-04-27 2019-10-31 The Regents Of The University Of California De novo formation of the biliary system by hepatocyte transdifferentiation
KR20230011948A (ko) * 2020-04-17 2023-01-25 더 카운실 오브 더 퀸즐랜드 인스티튜트 오브 메디컬 리서치 향상된 기능을 갖는 면역 세포
WO2023060186A1 (en) * 2021-10-07 2023-04-13 Hepatx Corporation Methods of tracking donor cells in a recipient
JPWO2023132371A1 (enExample) 2022-01-07 2023-07-13

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