JP2004528333A5 - - Google Patents
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- Publication number
- JP2004528333A5 JP2004528333A5 JP2002583390A JP2002583390A JP2004528333A5 JP 2004528333 A5 JP2004528333 A5 JP 2004528333A5 JP 2002583390 A JP2002583390 A JP 2002583390A JP 2002583390 A JP2002583390 A JP 2002583390A JP 2004528333 A5 JP2004528333 A5 JP 2004528333A5
- Authority
- JP
- Japan
- Prior art keywords
- diphenyl
- imidazole
- benzyloxy
- composition
- methoxy
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000000203 mixture Substances 0.000 claims 14
- 150000001875 compounds Chemical class 0.000 claims 11
- 239000002537 cosmetic Substances 0.000 claims 9
- 210000004400 mucous membrane Anatomy 0.000 claims 6
- 210000004761 scalp Anatomy 0.000 claims 6
- 230000007794 irritation Effects 0.000 claims 5
- UFWIBTONFRDIAS-UHFFFAOYSA-N Naphthalene Chemical compound C1=CC=CC2=CC=CC=C21 UFWIBTONFRDIAS-UHFFFAOYSA-N 0.000 claims 4
- 208000003251 Pruritus Diseases 0.000 claims 4
- 239000003795 chemical substances by application Substances 0.000 claims 4
- CPHGOBGXZQKCKI-UHFFFAOYSA-N 4,5-diphenyl-1h-imidazole Chemical compound N1C=NC(C=2C=CC=CC=2)=C1C1=CC=CC=C1 CPHGOBGXZQKCKI-UHFFFAOYSA-N 0.000 claims 3
- 206010020751 Hypersensitivity Diseases 0.000 claims 3
- 239000012190 activator Substances 0.000 claims 3
- 230000000694 effects Effects 0.000 claims 3
- RAXXELZNTBOGNW-UHFFFAOYSA-N imidazole Natural products C1=CNC=N1 RAXXELZNTBOGNW-UHFFFAOYSA-N 0.000 claims 3
- 230000002757 inflammatory effect Effects 0.000 claims 3
- 230000007803 itching Effects 0.000 claims 3
- 238000000034 method Methods 0.000 claims 3
- 201000004384 Alopecia Diseases 0.000 claims 2
- 208000002193 Pain Diseases 0.000 claims 2
- 208000026935 allergic disease Diseases 0.000 claims 2
- 239000002260 anti-inflammatory agent Substances 0.000 claims 2
- 229940121363 anti-inflammatory agent Drugs 0.000 claims 2
- 239000000118 hair dye Substances 0.000 claims 2
- 230000009610 hypersensitivity Effects 0.000 claims 2
- 239000008194 pharmaceutical composition Substances 0.000 claims 2
- 230000035807 sensation Effects 0.000 claims 2
- 230000037307 sensitive skin Effects 0.000 claims 2
- 208000017520 skin disease Diseases 0.000 claims 2
- YWLJCVIFYHUXDS-UHFFFAOYSA-N 4,5-diphenyl-1-(3-phenylmethoxypropyl)imidazole Chemical compound C1=NC(C=2C=CC=CC=2)=C(C=2C=CC=CC=2)N1CCCOCC1=CC=CC=C1 YWLJCVIFYHUXDS-UHFFFAOYSA-N 0.000 claims 1
- 241000894006 Bacteria Species 0.000 claims 1
- WVDDGKGOMKODPV-UHFFFAOYSA-N Benzyl alcohol Chemical compound OCC1=CC=CC=C1 WVDDGKGOMKODPV-UHFFFAOYSA-N 0.000 claims 1
- 229940123457 Free radical scavenger Drugs 0.000 claims 1
- ZFMITUMMTDLWHR-UHFFFAOYSA-N Minoxidil Chemical compound NC1=[N+]([O-])C(N)=CC(N2CCCCC2)=N1 ZFMITUMMTDLWHR-UHFFFAOYSA-N 0.000 claims 1
- 229930003316 Vitamin D Natural products 0.000 claims 1
- QYSXJUFSXHHAJI-XFEUOLMDSA-N Vitamin D3 Natural products C1(/[C@@H]2CC[C@@H]([C@]2(CCC1)C)[C@H](C)CCCC(C)C)=C/C=C1\C[C@@H](O)CCC1=C QYSXJUFSXHHAJI-XFEUOLMDSA-N 0.000 claims 1
- 239000013543 active substance Substances 0.000 claims 1
- 229940061720 alpha hydroxy acid Drugs 0.000 claims 1
- 150000001280 alpha hydroxy acids Chemical class 0.000 claims 1
- 150000004716 alpha keto acids Chemical class 0.000 claims 1
- 201000002996 androgenic alopecia Diseases 0.000 claims 1
- 239000000921 anthelmintic agent Substances 0.000 claims 1
- 229940124339 anthelmintic agent Drugs 0.000 claims 1
- 239000000058 anti acne agent Substances 0.000 claims 1
- 239000003242 anti bacterial agent Substances 0.000 claims 1
- 230000000340 anti-metabolite Effects 0.000 claims 1
- 230000001166 anti-perspirative effect Effects 0.000 claims 1
- 229940124340 antiacne agent Drugs 0.000 claims 1
- 229940121375 antifungal agent Drugs 0.000 claims 1
- 239000003429 antifungal agent Substances 0.000 claims 1
- 229940100197 antimetabolite Drugs 0.000 claims 1
- 239000002256 antimetabolite Substances 0.000 claims 1
- 239000003213 antiperspirant Substances 0.000 claims 1
- 239000003908 antipruritic agent Substances 0.000 claims 1
- 239000003443 antiviral agent Substances 0.000 claims 1
- 150000001277 beta hydroxy acids Chemical class 0.000 claims 1
- 150000004718 beta keto acids Chemical class 0.000 claims 1
- 239000004305 biphenyl Substances 0.000 claims 1
- 230000004069 differentiation Effects 0.000 claims 1
- 229940079593 drug Drugs 0.000 claims 1
- 239000003814 drug Substances 0.000 claims 1
- 239000000284 extract Substances 0.000 claims 1
- 239000003193 general anesthetic agent Substances 0.000 claims 1
- 208000024963 hair loss Diseases 0.000 claims 1
- 230000003676 hair loss Effects 0.000 claims 1
- 230000003659 hair regrowth Effects 0.000 claims 1
- 239000002563 ionic surfactant Substances 0.000 claims 1
- 239000003410 keratolytic agent Substances 0.000 claims 1
- 229910003002 lithium salt Inorganic materials 0.000 claims 1
- 159000000002 lithium salts Chemical class 0.000 claims 1
- 229960003632 minoxidil Drugs 0.000 claims 1
- 239000000041 non-steroidal anti-inflammatory agent Substances 0.000 claims 1
- 229940021182 non-steroidal anti-inflammatory drug Drugs 0.000 claims 1
- 239000002736 nonionic surfactant Substances 0.000 claims 1
- 230000003287 optical effect Effects 0.000 claims 1
- 239000003960 organic solvent Substances 0.000 claims 1
- 150000002978 peroxides Chemical class 0.000 claims 1
- 230000019612 pigmentation Effects 0.000 claims 1
- 239000003755 preservative agent Substances 0.000 claims 1
- 230000035755 proliferation Effects 0.000 claims 1
- 239000002516 radical scavenger Substances 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000000932 sedative agent Substances 0.000 claims 1
- 230000001624 sedative effect Effects 0.000 claims 1
- 239000002294 steroidal antiinflammatory agent Substances 0.000 claims 1
- 230000003637 steroidlike Effects 0.000 claims 1
- 208000024891 symptom Diseases 0.000 claims 1
- 235000019166 vitamin D Nutrition 0.000 claims 1
- 239000011710 vitamin D Substances 0.000 claims 1
- 150000003710 vitamin D derivatives Chemical class 0.000 claims 1
- 229940046008 vitamin d Drugs 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR0105497A FR2823747B1 (fr) | 2001-04-24 | 2001-04-24 | Nouveaux composes de la famille des 3-alkyl-(4,5 diphenyl- imidazol-1-yl) et leur utilisation comme anti-inflammatoires |
| PCT/FR2002/001411 WO2002085863A1 (fr) | 2001-04-24 | 2002-04-24 | Composes de la famille des 3-alkyl-(4, 5 diphenyl-imidazol-1-yl) et leur utilisation comme apaisants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004528333A JP2004528333A (ja) | 2004-09-16 |
| JP2004528333A5 true JP2004528333A5 (https=) | 2006-01-05 |
Family
ID=8862628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002583390A Withdrawn JP2004528333A (ja) | 2001-04-24 | 2002-04-24 | ３−アルキル−（４，５−ジフェニル−イミダゾル−１−イル）ファミリーの新規な化合物及び鎮静剤としてのその用途 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US20040192928A1 (https=) |
| EP (1) | EP1385827A1 (https=) |
| JP (1) | JP2004528333A (https=) |
| KR (2) | KR100602826B1 (https=) |
| CN (1) | CN1330637C (https=) |
| FR (1) | FR2823747B1 (https=) |
| WO (1) | WO2002085863A1 (https=) |
Families Citing this family (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20140227208A1 (en) * | 2013-02-08 | 2014-08-14 | The Procter & Gamble Company | Cosmetic compositions containing substituted azole and methods for alleviating mechanically-induced skin inflammation |
| CN108752663B (zh) * | 2018-04-23 | 2021-03-26 | 龙岩学院 | 一种纳米蜂胶负载碳酸钙空心微球/天然胶乳抗菌复合膜的制备方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3258466A (en) * | 1961-12-07 | 1966-06-28 | Kawakami Iwao | 1-hydroxyethyl-4, 5-diphenylimidazole |
| GB1182551A (en) * | 1967-03-01 | 1970-02-25 | Teikoku Hormone Mfg Co Ltd | Substituted Diphenyl Imidazoles and their production and use |
| US3707475A (en) * | 1970-11-16 | 1972-12-26 | Pfizer | Antiinflammatory imidazoles |
| US3929807A (en) * | 1971-05-10 | 1975-12-30 | Ciba Geigy Corp | 2-Substituted-4(5)-(aryl)-5(4)-(2,3 or -4-pyridyl)-imidazoles |
| US3759946A (en) * | 1971-09-20 | 1973-09-18 | Teikoku Hormone Mfg Co Ltd | 1-aryloxy-4,5-diphenylimidazoles |
| US4182769A (en) * | 1977-02-09 | 1980-01-08 | E. I. Du Pont De Nemours And Company | Anti-inflammatory 1-substituted-4,5-diaryl-2-(substituted-thio) imidazoles and their corresponding sulfoxides and sulfones |
| KR100291112B1 (ko) * | 1992-02-11 | 2001-09-17 | 더 존스 홉킨스 유니버시티 | 코엔자임에이-독립성트랜스아실라제및혈소판활성화인자억제제 |
| IL110296A (en) * | 1993-07-16 | 1999-12-31 | Smithkline Beecham Corp | Imidazole compounds process for their preparation and pharmaceutical compositions containing them |
-
2001
- 2001-04-24 FR FR0105497A patent/FR2823747B1/fr not_active Expired - Fee Related
-
2002
- 2002-04-24 CN CNB02812099XA patent/CN1330637C/zh not_active Expired - Fee Related
- 2002-04-24 KR KR1020037013961A patent/KR100602826B1/ko not_active Expired - Fee Related
- 2002-04-24 JP JP2002583390A patent/JP2004528333A/ja not_active Withdrawn
- 2002-04-24 EP EP02726274A patent/EP1385827A1/fr not_active Withdrawn
- 2002-04-24 KR KR1020067005892A patent/KR100667647B1/ko not_active Expired - Fee Related
- 2002-04-24 US US10/475,652 patent/US20040192928A1/en not_active Abandoned
- 2002-04-24 WO PCT/FR2002/001411 patent/WO2002085863A1/fr not_active Ceased
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