JP2004528316A - 癌治療のための、レチノイド受容体リガンドおよび選択される細胞毒性剤の相乗的な組み合わせ - Google Patents
癌治療のための、レチノイド受容体リガンドおよび選択される細胞毒性剤の相乗的な組み合わせ Download PDFInfo
- Publication number
- JP2004528316A JP2004528316A JP2002576888A JP2002576888A JP2004528316A JP 2004528316 A JP2004528316 A JP 2004528316A JP 2002576888 A JP2002576888 A JP 2002576888A JP 2002576888 A JP2002576888 A JP 2002576888A JP 2004528316 A JP2004528316 A JP 2004528316A
- Authority
- JP
- Japan
- Prior art keywords
- rarα
- cytotoxic agent
- rar
- paclitaxel
- selective agonist
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- AUVBSAHVCMADGF-UHFFFAOYSA-N CC(C)(c1cc(ccc(-c(cc2)ccc2C(OC)=O)c2)c2cc1C(c1cccc(C)c1)=C1)C1=O Chemical compound CC(C)(c1cc(ccc(-c(cc2)ccc2C(OC)=O)c2)c2cc1C(c1cccc(C)c1)=C1)C1=O AUVBSAHVCMADGF-UHFFFAOYSA-N 0.000 description 1
Images
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
- A61K31/337—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having four-membered rings, e.g. taxol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US27775401P | 2001-03-22 | 2001-03-22 | |
| PCT/US2002/008718 WO2002078620A2 (en) | 2001-03-22 | 2002-03-22 | Synergistic combinations of retinoid receptor ligands and selected cytotoxic agents for treatment of cancer |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004528316A true JP2004528316A (ja) | 2004-09-16 |
| JP2004528316A5 JP2004528316A5 (https=) | 2005-12-22 |
Family
ID=23062213
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002576888A Withdrawn JP2004528316A (ja) | 2001-03-22 | 2002-03-22 | 癌治療のための、レチノイド受容体リガンドおよび選択される細胞毒性剤の相乗的な組み合わせ |
Country Status (15)
| Country | Link |
|---|---|
| EP (1) | EP1383491A2 (https=) |
| JP (1) | JP2004528316A (https=) |
| KR (1) | KR20030086314A (https=) |
| CN (1) | CN1498105A (https=) |
| BR (1) | BR0207681A (https=) |
| CA (1) | CA2441335A1 (https=) |
| CZ (1) | CZ20032540A3 (https=) |
| DE (1) | DE02733871T1 (https=) |
| ES (1) | ES2214985T1 (https=) |
| HU (1) | HUP0400255A2 (https=) |
| IL (1) | IL157358A0 (https=) |
| MX (1) | MXPA03008403A (https=) |
| PL (1) | PL368946A1 (https=) |
| TR (1) | TR200400812T3 (https=) |
| WO (1) | WO2002078620A2 (https=) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007108272A1 (ja) * | 2006-03-23 | 2007-09-27 | Tmrc Co., Ltd. | 癌治療用キットおよび癌治療用医薬組成物 |
-
2002
- 2002-03-22 WO PCT/US2002/008718 patent/WO2002078620A2/en not_active Ceased
- 2002-03-22 TR TR2004/00812T patent/TR200400812T3/xx unknown
- 2002-03-22 CA CA002441335A patent/CA2441335A1/en not_active Abandoned
- 2002-03-22 IL IL15735802A patent/IL157358A0/xx unknown
- 2002-03-22 DE DE0001383491T patent/DE02733871T1/de active Pending
- 2002-03-22 JP JP2002576888A patent/JP2004528316A/ja not_active Withdrawn
- 2002-03-22 PL PL02368946A patent/PL368946A1/xx not_active Application Discontinuation
- 2002-03-22 HU HU0400255A patent/HUP0400255A2/hu unknown
- 2002-03-22 ES ES02733871T patent/ES2214985T1/es active Pending
- 2002-03-22 BR BR0207681-0A patent/BR0207681A/pt not_active Application Discontinuation
- 2002-03-22 MX MXPA03008403A patent/MXPA03008403A/es unknown
- 2002-03-22 CN CNA028070011A patent/CN1498105A/zh active Pending
- 2002-03-22 KR KR10-2003-7012217A patent/KR20030086314A/ko not_active Withdrawn
- 2002-03-22 EP EP02733871A patent/EP1383491A2/en not_active Withdrawn
- 2002-03-22 CZ CZ20032540A patent/CZ20032540A3/cs unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2007108272A1 (ja) * | 2006-03-23 | 2007-09-27 | Tmrc Co., Ltd. | 癌治療用キットおよび癌治療用医薬組成物 |
Also Published As
| Publication number | Publication date |
|---|---|
| CN1498105A (zh) | 2004-05-19 |
| PL368946A1 (pl) | 2005-04-04 |
| IL157358A0 (en) | 2004-02-19 |
| BR0207681A (pt) | 2004-07-27 |
| HUP0400255A2 (hu) | 2004-08-30 |
| KR20030086314A (ko) | 2003-11-07 |
| DE02733871T1 (de) | 2004-08-26 |
| TR200400812T3 (tr) | 2004-07-21 |
| ES2214985T1 (es) | 2004-10-01 |
| WO2002078620A2 (en) | 2002-10-10 |
| CA2441335A1 (en) | 2002-10-10 |
| CZ20032540A3 (cs) | 2004-05-12 |
| WO2002078620A3 (en) | 2003-04-17 |
| MXPA03008403A (es) | 2004-01-29 |
| EP1383491A2 (en) | 2004-01-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Leeman et al. | STAT3 as a therapeutic target in head and neck cancer | |
| US6130230A (en) | Therapeutic combinations of RAR antagonists and RXR agonists and use thereof | |
| ES2544482T3 (es) | Compuesto rexinoide que tiene un grupo alcoxi | |
| Zusi et al. | Selective retinoids and rexinoids in cancer therapy and chemoprevention | |
| Han et al. | Differentiation of human neuroblastoma by phenylacetate is mediated by peroxisome proliferator-activated receptor γ | |
| Campbell et al. | Expression of retinoic acid receptor-β sensitizes prostate cancer cells to growth inhibition mediated by combinations of retinoids and a 19-nor hexafluoride vitamin D3 analog | |
| JP2000256194A (ja) | 核内レセプタ作動薬およびその効果増強剤 | |
| JP2014076953A (ja) | レチノイドx受容体パーシャルアゴニスト化合物及びこのレチノイドx受容体パーシャルアゴニスト化合物を有効成分として含有する薬剤 | |
| JP5255994B2 (ja) | 核内受容体リガンド | |
| Traves et al. | Selective activation of liver X receptors by acanthoic acid-related diterpenes | |
| JP4435418B2 (ja) | 新規レチノイドおよびその使用法 | |
| EP0850067A1 (en) | Method for treating cancers using 6- 3- 1-adamantyl]-4-hydroxyphenyl] | |
| US6184256B1 (en) | Methods and compositions for use in modulating expression of matrix metalloproteinase genes | |
| AU773928B2 (en) | Compositions and methods for treatment of hyperproliferative diseases | |
| JP5885140B2 (ja) | Rxrパーシャルアゴニスト | |
| US20040122080A1 (en) | Synergist combinations of retinoid receptor ligands and selected cytotoxic agents for treatment of cancer | |
| JP2004528316A (ja) | 癌治療のための、レチノイド受容体リガンドおよび選択される細胞毒性剤の相乗的な組み合わせ | |
| US6624154B1 (en) | Compositions and methods for treatment of hyperproliferative diseases | |
| Marchwicka et al. | Therapeutic use of selective synthetic ligands for retinoic acid receptors: a patent review | |
| AU2002305072A1 (en) | Synergistic combinations of retinoid receptor ligands and selected cytotoxic agents for treatment of cancer | |
| Lei et al. | Retinoids and retinoic acid receptor in cancer | |
| WO2002022113A2 (en) | Retinoic acid receptor antagonists as promoters of angiogenesis | |
| JP4904498B2 (ja) | Rar活性化を起こす天然化合物 | |
| JP2006526662A (ja) | 過増殖性細胞疾患を治療する方法 | |
| JP2005053780A (ja) | 核内レセプタースーパーファミリーの新規リガンド、その製法及び用途 |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A521 | Request for written amendment filed |
Free format text: JAPANESE INTERMEDIATE CODE: A523 Effective date: 20050215 |
|
| A621 | Written request for application examination |
Free format text: JAPANESE INTERMEDIATE CODE: A621 Effective date: 20050215 |
|
| A761 | Written withdrawal of application |
Free format text: JAPANESE INTERMEDIATE CODE: A761 Effective date: 20051208 |