JP2004521933A5 - - Google Patents
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- Publication number
- JP2004521933A5 JP2004521933A5 JP2002573027A JP2002573027A JP2004521933A5 JP 2004521933 A5 JP2004521933 A5 JP 2004521933A5 JP 2002573027 A JP2002573027 A JP 2002573027A JP 2002573027 A JP2002573027 A JP 2002573027A JP 2004521933 A5 JP2004521933 A5 JP 2004521933A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- active ingredient
- extract
- kawamidori
- medicament
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 239000008194 pharmaceutical composition Substances 0.000 claims 11
- 239000004480 active ingredient Substances 0.000 claims 10
- 238000004519 manufacturing process Methods 0.000 claims 6
- 239000003814 drug Substances 0.000 claims 5
- HEDRZPFGACZZDS-UHFFFAOYSA-N Chloroform Chemical compound ClC(Cl)Cl HEDRZPFGACZZDS-UHFFFAOYSA-N 0.000 claims 4
- LRHPLDYGYMQRHN-UHFFFAOYSA-N N-Butanol Chemical compound CCCCO LRHPLDYGYMQRHN-UHFFFAOYSA-N 0.000 claims 4
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 claims 4
- VLKZOEOYAKHREP-UHFFFAOYSA-N n-Hexane Chemical compound CCCCCC VLKZOEOYAKHREP-UHFFFAOYSA-N 0.000 claims 4
- 201000010099 disease Diseases 0.000 claims 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 claims 3
- NLZCOTZRUWYPTP-MIUGBVLSSA-N 5-hydroxy-2-(4-methoxyphenyl)-7-[(2s,3r,4s,5s,6r)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxychromen-4-one Chemical compound C1=CC(OC)=CC=C1C(OC1=C2)=CC(=O)C1=C(O)C=C2O[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](CO)O1 NLZCOTZRUWYPTP-MIUGBVLSSA-N 0.000 claims 2
- 201000001320 Atherosclerosis Diseases 0.000 claims 2
- 102000006818 Cell Adhesion Molecule-1 Human genes 0.000 claims 2
- 108010072135 Cell Adhesion Molecule-1 Proteins 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 2
- NLZCOTZRUWYPTP-UHFFFAOYSA-N acacetin-7-O-beta-D-galactoside Natural products C1=CC(OC)=CC=C1C(OC1=C2)=CC(=O)C1=C(O)C=C2OC1C(O)C(O)C(O)C(CO)O1 NLZCOTZRUWYPTP-UHFFFAOYSA-N 0.000 claims 2
- 230000000879 anti-atherosclerotic effect Effects 0.000 claims 2
- 230000003110 anti-inflammatory effect Effects 0.000 claims 2
- 230000004154 complement system Effects 0.000 claims 2
- 239000002778 food additive Substances 0.000 claims 2
- 235000013373 food additive Nutrition 0.000 claims 2
- 230000004054 inflammatory process Effects 0.000 claims 2
- 230000028709 inflammatory response Effects 0.000 claims 2
- 239000000203 mixture Substances 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 239000002904 solvent Substances 0.000 claims 2
- GWOKWCRSUJQOMD-UHFFFAOYSA-N tilianin Natural products C1=CC(OC)=CC=C1C(OC1=C2)=CC(=O)C1=CC=C2OC1C(O)C(O)C(O)C(CO)O1 GWOKWCRSUJQOMD-UHFFFAOYSA-N 0.000 claims 2
- 240000004510 Agastache rugosa Species 0.000 claims 1
- 235000010686 Agastache rugosa Nutrition 0.000 claims 1
- 230000002401 inhibitory effect Effects 0.000 claims 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| KR20010009977 | 2001-02-27 | ||
| PCT/KR2001/002224 WO2002074320A1 (en) | 2001-02-27 | 2001-12-20 | Agastache rugosa extract and composition containing tilianin isolated and purified from said extract having anti-inflammatory activity and anti-atherogenic activity |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2004521933A JP2004521933A (ja) | 2004-07-22 |
| JP2004521933A5 true JP2004521933A5 (https=) | 2005-05-26 |
| JP4091436B2 JP4091436B2 (ja) | 2008-05-28 |
Family
ID=19706307
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002573027A Expired - Fee Related JP4091436B2 (ja) | 2001-02-27 | 2001-12-20 | 抗炎症活性および抗アテローム生成活性を示すカワミドリ抽出物およびそれから単離され、精製されたチリアニンを含有する組成物 |
Country Status (8)
| Country | Link |
|---|---|
| US (2) | US20040071792A1 (https=) |
| EP (1) | EP1363648B8 (https=) |
| JP (1) | JP4091436B2 (https=) |
| KR (1) | KR100447948B1 (https=) |
| CN (1) | CN100376255C (https=) |
| CA (1) | CA2439430C (https=) |
| DE (1) | DE60124591T2 (https=) |
| WO (1) | WO2002074320A1 (https=) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20060003030A1 (en) * | 2004-07-01 | 2006-01-05 | Lin Chun-Ying | Essential oils for treating and/ or preventing allergic disease |
| KR100807645B1 (ko) * | 2006-10-17 | 2008-02-28 | 주식회사 유니젠 | 위장질환 치료 및 예방용 조성물 및 그의 제조방법 |
| KR100851489B1 (ko) * | 2006-11-30 | 2008-08-08 | (주)아모레퍼시픽 | 틸리아닌( ｔｉｌｉａｎｉｎ) 또는아카세틴(ａｃａｃｅｔｉｎ)을 유효성분으로 함유하는화장료 조성물 |
| DE202008011721U1 (de) * | 2008-09-03 | 2008-12-24 | American Phoenix Biotech Inc., Hacienda Heights | Pflanzliche Zusammensetzung zur Behandlung von Krebs |
| KR101540310B1 (ko) * | 2013-08-07 | 2015-07-30 | 건국대학교 산학협력단 | 방아풀 추출물을 함유하는 신경 염증 예방 및 치료용 조성물, 그리고 방아풀 추출물 추출 방법 |
| CN107429226A (zh) * | 2015-01-06 | 2017-12-01 | 株式会社露太利温 | luterion及其分离和培养方法 |
| PL412214A1 (pl) | 2015-05-04 | 2016-11-07 | Biovico Spółka Z Ograniczoną Odpowiedzialnością | Kompozycja roślinna o właściwościach przeciwzapalnych, przeciwalergicznych i/lub przeciwastmatycznych oraz jej zastosowanie |
| KR102049875B1 (ko) | 2018-06-29 | 2019-11-28 | 충북대학교 산학협력단 | 에키나세아 배양근 유래 신규 화합물 및 이의 항염증 용도 |
| CN111171094B (zh) * | 2018-11-13 | 2023-06-16 | 上海医药工业研究院有限公司 | 一种香清兰苷中间体及其制备方法和应用 |
| US12472221B2 (en) * | 2019-05-23 | 2025-11-18 | Korea Institute Of Oriental Medicine | Composition for inhibiting osteoclasts containing agastache rugosa extract as active ingredient, and use thereof |
| KR102339923B1 (ko) * | 2019-11-12 | 2021-12-20 | 한국한의학연구원 | 혈행 개선용 식치제호탕 조성물 |
| KR102300732B1 (ko) * | 2020-11-11 | 2021-09-14 | 주식회사 제이에스무역 | 난황유 및 배초향 줄기세포를 함유하는 항산화, 미백, 항주름 또는 항염증용 조성물 |
| JP2025143197A (ja) * | 2024-03-18 | 2025-10-01 | ペガヴィジョン コーポレーション | 皮膚バリア強化及び抗炎症用のカワミドリエキソソーム組成物及びその用途 |
Family Cites Families (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3831196A1 (de) * | 1988-09-14 | 1990-03-22 | Bosch Gmbh Robert | Elektromagnetisch betaetigbares ventil |
| CN1060772A (zh) * | 1991-10-30 | 1992-05-06 | 阳山县食品厂 | 一种藿香姜计陈皮的生产工艺 |
| CN1057447C (zh) * | 1993-01-22 | 2000-10-18 | 马军营 | 一种治疗小儿腹泻的口服液 |
| CN1117388A (zh) * | 1994-08-24 | 1996-02-28 | 东营市面粉厂 | 复方柴胡擦剂 |
| JPH08176002A (ja) * | 1994-12-27 | 1996-07-09 | Kao Corp | 細胞接着抑制剤 |
| KR970007366A (ko) * | 1995-07-31 | 1997-02-21 | 고제섭 | 압축단자 접촉저항 측정장치 및 그 방법 |
| CN1151881A (zh) * | 1995-12-01 | 1997-06-18 | 陶周行 | 一种阴道冲洗保留剂及其制备工艺与使用方法 |
| CA2272540C (en) * | 1996-09-27 | 2009-09-01 | Takeshi Karita | Anti-oxidizing composition for scavenging free radicals, pharmaceutical composition comprising the same, and process for preparing the same |
| US5776462A (en) * | 1996-12-10 | 1998-07-07 | Sage R&D, A Partnership | Pogostemon cablin extract for inhibiting H. influenzae adhesion and treating otitis media or sore throat |
| KR100232053B1 (ko) * | 1997-04-22 | 1999-12-01 | 김동태 | DPPH(1,1-diphenyl-2-picrylhydrazyl)를 이용한 항산화물질의 분석방법 |
| JP4231559B2 (ja) * | 1997-04-23 | 2009-03-04 | オリザ油化株式会社 | リポキシゲナーゼ阻害剤 |
| KR100215400B1 (ko) * | 1997-05-27 | 1999-08-16 | 김진수 | 건강보조식품용 유중수적형 영양음료 및 그 제조방법 |
| KR100309071B1 (ko) * | 1998-09-02 | 2001-12-17 | 성재갑 | 콜라겐합성촉진제를함유한피부용조성물 |
| KR100341798B1 (ko) * | 1999-08-04 | 2002-06-26 | 대한민국 (관리청:특허청장, 승계청:농촌진흥청장) | 방아잎으로부터 로즈마린산을 분리하는 방법 |
| WO2001045725A2 (en) * | 1999-12-23 | 2001-06-28 | Ancile Pharmaceuticals, Inc. | Treatment for inflammatory bowel disease (ibd) and related conditions |
| KR100376306B1 (ko) * | 2000-08-07 | 2003-03-17 | 한완석 | 혈액순환 촉진용 건강식품 조성물 |
| CN1126453C (zh) * | 2000-08-09 | 2003-11-05 | 郭兴华 | 天然抗菌组合物及其应用 |
| CN1282537A (zh) * | 2000-08-22 | 2001-02-07 | 张益� | 一种藿香饮料 |
-
2001
- 2001-07-03 KR KR10-2001-0039574A patent/KR100447948B1/ko not_active Expired - Fee Related
- 2001-12-20 US US10/469,025 patent/US20040071792A1/en not_active Abandoned
- 2001-12-20 WO PCT/KR2001/002224 patent/WO2002074320A1/en not_active Ceased
- 2001-12-20 CN CNB018230695A patent/CN100376255C/zh not_active Expired - Fee Related
- 2001-12-20 DE DE60124591T patent/DE60124591T2/de not_active Expired - Lifetime
- 2001-12-20 CA CA2439430A patent/CA2439430C/en not_active Expired - Fee Related
- 2001-12-20 JP JP2002573027A patent/JP4091436B2/ja not_active Expired - Fee Related
- 2001-12-20 EP EP01274005A patent/EP1363648B8/en not_active Expired - Lifetime
-
2007
- 2007-05-23 US US11/802,527 patent/US7534456B2/en not_active Expired - Fee Related
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