JP2004521108A5 - - Google Patents

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Publication number
JP2004521108A5
JP2004521108A5 JP2002558467A JP2002558467A JP2004521108A5 JP 2004521108 A5 JP2004521108 A5 JP 2004521108A5 JP 2002558467 A JP2002558467 A JP 2002558467A JP 2002558467 A JP2002558467 A JP 2002558467A JP 2004521108 A5 JP2004521108 A5 JP 2004521108A5
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JP
Japan
Prior art keywords
peptide
test compound
composition
δpkc
absence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002558467A
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English (en)
Japanese (ja)
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JP4115838B2 (ja
JP2004521108A (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/047556 external-priority patent/WO2002057413A2/en
Publication of JP2004521108A publication Critical patent/JP2004521108A/ja
Publication of JP2004521108A5 publication Critical patent/JP2004521108A5/ja
Application granted granted Critical
Publication of JP4115838B2 publication Critical patent/JP4115838B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002558467A 2001-01-18 2001-11-09 δＰＫＣの活性化および阻害のためのペプチド Expired - Fee Related JP4115838B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26206001P 2001-01-18 2001-01-18
PCT/US2001/047556 WO2002057413A2 (en) 2001-01-18 2001-11-09 Peptides for activation and inhibition of delta pkc

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008048806A Division JP4592772B2 (ja) 2001-01-18 2008-02-28 δＰＫＣの活性化および阻害のためのペプチド

Publications (3)

Publication Number Publication Date
JP2004521108A JP2004521108A (ja) 2004-07-15
JP2004521108A5 true JP2004521108A5 (https=) 2006-01-05
JP4115838B2 JP4115838B2 (ja) 2008-07-09

Family

ID=22995990

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002558467A Expired - Fee Related JP4115838B2 (ja) 2001-01-18 2001-11-09 δＰＫＣの活性化および阻害のためのペプチド
JP2008048806A Expired - Fee Related JP4592772B2 (ja) 2001-01-18 2008-02-28 δＰＫＣの活性化および阻害のためのペプチド

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008048806A Expired - Fee Related JP4592772B2 (ja) 2001-01-18 2008-02-28 δＰＫＣの活性化および阻害のためのペプチド

Country Status (6)

Country Link
US (5) US6855693B2 (https=)
EP (2) EP2338899A1 (https=)
JP (2) JP4115838B2 (https=)
AU (1) AU2002226061B2 (https=)
CA (1) CA2434643C (https=)
WO (1) WO2002057413A2 (https=)

Families Citing this family (46)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020168354A1 (en) * 2000-11-10 2002-11-14 Daria Mochly-Rosen psiepsilonRack peptide composition and method for protection against tissue damage due to ischemia
WO2002057413A2 (en) * 2001-01-18 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Peptides for activation and inhibition of delta pkc
US7645739B2 (en) * 2001-02-21 2010-01-12 Alavita Pharmaceuticals, Inc. Modified annexin compositions and methods of using same
WO2004045535A2 (en) * 2002-11-14 2004-06-03 Arbor Vita Corporation Molecular interactions in neurons
JP2005527209A (ja) 2002-04-22 2005-09-15 ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー 疼痛管理のためのプロテインキナーゼＣγのペプチドインヒビター
US20110002978A1 (en) 2003-06-17 2011-01-06 Harrison Roger G Enzyme prodrug cancer therapy selectively targeted to tumor cells or tumor vasculature and methods of production and use thereof
BRPI0414714A (pt) * 2003-09-24 2006-11-21 Pasteur Institut polinucleotìdeo purificado, vetor, célula hospedeira, construto de fusão de polipeptìdeo, métodos de inibir a rota de sinalização de nf-capab, de interromper a oligomerização de nemo, e, de identificar polipeptìdeos que modulam a oligomerização de nemo, e, uso de uma quantidade eficaz de uma composição
AU2004298048A1 (en) * 2003-12-09 2005-06-23 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for modulating mitochondrial aldehyde dehydrogenase-2
WO2005065666A1 (en) * 2003-12-22 2005-07-21 Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services Us of a pkc-delta inhibitor for the inhibition of metastatic melanoma
US20050267030A1 (en) * 2004-04-30 2005-12-01 Tsao Philip S Use of deltaPKC peptides for modulation of reactive oxygen species
EP1784483A2 (en) * 2004-08-02 2007-05-16 The Board Of Trustees Of The Leland Stanford Junior University Peptide sequence for modulation of delta protein kinase c
US7265092B2 (en) * 2004-09-30 2007-09-04 Kai Pharmaceuticals, Inc. Pharmaceutical formulation
US20060148700A1 (en) * 2004-11-10 2006-07-06 Daria Mochly-Rosen Methods and compositions for reducing injury to a transplanted organ
EP1846016A2 (en) * 2005-01-04 2007-10-24 The Board Of Trustees Of The Leland Stanford Junior University Methods of increasing cerebral blood flow
US20060160062A1 (en) * 2005-01-14 2006-07-20 Young Lindon H Perfusion and/or preservation solution for organs
US20090186814A1 (en) * 2005-01-26 2009-07-23 Fumiaki Ikeno Methods and Compositions for Reducing Ischemia-Derived Microvascular Damage
WO2006095086A2 (fr) * 2005-03-07 2006-09-14 Laurence Faure Traçabilite des anomalies du cycle cellulaire ciblant l'oncologie et la neurodegenerescence.
WO2007027974A1 (en) * 2005-09-02 2007-03-08 The Board Of Trustees Of The Leland Stanford Junior University Method for reducing risk of and extent of injury due to stroke in hypertensive subjects
CA2644089A1 (en) * 2005-09-19 2007-03-29 Kai Pharmaceuticals, Inc. Protein kinase c peptide modulators of angiogenesis
DK2056851T3 (da) * 2005-12-09 2013-10-14 Philadelphia College Of Osteopathic Medicine Organkonservering og/eller -perfusion
US20070148628A1 (en) * 2005-12-09 2007-06-28 Philadelphia College Of Osteopathic Medicine Organ preservation and/or perfusion
WO2008042421A2 (en) * 2006-10-02 2008-04-10 The Board Of Trustees Of The Leland Stanford Junior University Peptides derived from the c2 domain of epsilon pkc, and use thereof
JP5645408B2 (ja) * 2006-11-16 2014-12-24 カイ ファーマシューティカルズ インコーポレーティッド 副甲状腺機能亢進症および高カルシウム血症性障害の治療のためのポリカチオン性カルシウムモジュレーターペプチド
WO2008080153A2 (en) * 2006-12-22 2008-07-03 The Children's Hospital Of Philadelphia A novel protein kinase c therapy for the treatment of acute lung injury
US20080293640A1 (en) * 2007-01-10 2008-11-27 Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of Polypeptide inhibitors of HSP27 kinase and uses therefor
AU2007342674B2 (en) * 2007-01-10 2013-09-19 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and uses therefor
CA2989778C (en) * 2007-01-19 2020-06-30 Kai Pharmaceuticals, Inc. Method of modifying peptide compositions
US20090062208A1 (en) * 2007-02-06 2009-03-05 Mochly-Rosen Daria D Methods for maintaining blood-brain barrier integrity in hypertensive subjects using a delta-PKC inhibitor
KR100906153B1 (ko) 2007-07-04 2009-07-03 재단법인 한국원자력의학원 프로테인 카이네즈 씨 활성 저해용 단백질 및 이를포함하는 약제학적 조성물
JP5703466B2 (ja) * 2007-08-07 2015-04-22 パーデュー・リサーチ・ファウンデーションＰｕｒｄｕｅ Ｒｅｓｅａｒｃｈ Ｆｏｕｎｄａｔｉｏｎ キナーゼ阻害薬およびその使用
AU2008293496A1 (en) * 2007-08-27 2009-03-05 Kai Pharmaceuticals, Inc. Protein kinase C-delta inhibitors that protect against cellular injury and inflammation and promote astrocyte proliferation
WO2009065080A1 (en) * 2007-11-16 2009-05-22 San Diego State University Research Foundation Compositions and method for manipulating pim-1 activity in circulatory system cells
US20090318351A1 (en) * 2008-03-12 2009-12-24 Kevin Grimes Method of treating acute st-elevation myocardial infarction with a delta pkc antagonist
WO2010019965A1 (en) * 2008-08-15 2010-02-18 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for modulating epsilon protein kinase c-mediated cytoprotection
CA2744104C (en) 2008-12-10 2017-07-18 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US9890195B2 (en) * 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
US8999932B2 (en) 2009-07-29 2015-04-07 Kai Pharmaceuticals, Inc. Therapeutic agents for reducing parathyroid hormone levels
EP2482837A4 (en) 2009-09-29 2013-05-22 Joslin Diabetes Center Inc USE OF PROTEIN KINASE C-DELTA (PKCD) INHIBITORS FOR THE TREATMENT OF DIABETES, ADIPOSITAS AND LIVER VARIATION
HRP20161566T1 (hr) 2011-06-08 2017-02-24 Kai Pharmaceuticals, Inc. Terapijski agensi za reguliranje serumskog fosfora
EP2742057B1 (en) * 2011-08-12 2016-04-20 The Board of Trustees of The Leland Stanford Junior University Compositions and methods for specific regulation of pyruvate dehydrogenase kinase
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
KR101611494B1 (ko) 2012-12-20 2016-04-12 한양대학교 산학협력단 ＰＫＣ－δ 검출용 폴리펩티드 및 이의 용도
US9987241B2 (en) 2014-09-25 2018-06-05 The Board Of Regents Of The University Of Oklahoma Enzyme conjugate and prodrug cancer therapy
CN106467493B (zh) * 2015-08-14 2021-04-23 苏州兰鼎生物制药有限公司 一种治疗缺血性脑卒中后遗症的化合物
US11446365B2 (en) 2017-08-09 2022-09-20 The Board Of Regents Of The University Of Oklahoma Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same
KR20220159945A (ko) * 2020-03-31 2022-12-05 도레이 카부시키가이샤 화상 해석 장치, 화상 해석 장치의 제어 방법, 화상 해석 시스템, 및 화상 해석 시스템의 제어 방법

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1247080A (en) * 1983-03-08 1988-12-20 Commonwealth Serum Laboratories Commission Antigenically active amino acid sequences
US5804604A (en) 1989-12-21 1998-09-08 Biogen, Inc. Tat-derived transport polypeptides and fusion proteins
US5776716A (en) * 1994-02-01 1998-07-07 Terrapin Technologies, Inc. Methods for identifying agents which block the interaction of fyn with PKC-theta, and uses thereof
US5935803A (en) * 1994-02-01 1999-08-10 Terrapin Technologies, Inc. Methods to identify immunomodulators using cognate interaction of PKC-theta
US5519003A (en) 1994-02-01 1996-05-21 Board Of Trustees Of The Leland Stanford Junior University WD-40-derived peptides and uses thereof
US5783405A (en) * 1994-02-01 1998-07-21 Terrapin Technologies, Inc. Rapid screening method for effectors of signal transduction
WO1998017299A1 (en) * 1996-10-18 1998-04-30 The Board Of Trustees Of The Leland Stanford Junior University Isozyme-specific activators of protein kinase c, methods and compositions
US6228843B1 (en) * 1999-04-23 2001-05-08 University Technology Corporation Method of using PKC inhibiting compounds to treat vascular disease
US6664040B2 (en) 2000-05-23 2003-12-16 The Regents Of The University Of California Compositions and methods for delivery of a molecule into a cell
WO2002057413A2 (en) 2001-01-18 2002-07-25 The Board Of Trustees Of The Leland Stanford Junior University Peptides for activation and inhibition of delta pkc
US7224668B1 (en) * 2002-11-27 2007-05-29 Cisco Technology, Inc. Control plane security and traffic flow management
US7265092B2 (en) 2004-09-30 2007-09-04 Kai Pharmaceuticals, Inc. Pharmaceutical formulation
US20060148700A1 (en) * 2004-11-10 2006-07-06 Daria Mochly-Rosen Methods and compositions for reducing injury to a transplanted organ
EP1846016A2 (en) 2005-01-04 2007-10-24 The Board Of Trustees Of The Leland Stanford Junior University Methods of increasing cerebral blood flow
US20090186814A1 (en) 2005-01-26 2009-07-23 Fumiaki Ikeno Methods and Compositions for Reducing Ischemia-Derived Microvascular Damage
US20090062208A1 (en) 2007-02-06 2009-03-05 Mochly-Rosen Daria D Methods for maintaining blood-brain barrier integrity in hypertensive subjects using a delta-PKC inhibitor
AU2008293496A1 (en) 2007-08-27 2009-03-05 Kai Pharmaceuticals, Inc. Protein kinase C-delta inhibitors that protect against cellular injury and inflammation and promote astrocyte proliferation

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