JP2004521108A5 - - Google Patents

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Publication number
JP2004521108A5
JP2004521108A5 JP2002558467A JP2002558467A JP2004521108A5 JP 2004521108 A5 JP2004521108 A5 JP 2004521108A5 JP 2002558467 A JP2002558467 A JP 2002558467A JP 2002558467 A JP2002558467 A JP 2002558467A JP 2004521108 A5 JP2004521108 A5 JP 2004521108A5
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JP
Japan
Prior art keywords
peptide
test compound
composition
δpkc
absence
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2002558467A
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English (en)
Japanese (ja)
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JP2004521108A (ja
JP4115838B2 (ja
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Publication date
Application filed filed Critical
Priority claimed from PCT/US2001/047556 external-priority patent/WO2002057413A2/en
Publication of JP2004521108A publication Critical patent/JP2004521108A/ja
Publication of JP2004521108A5 publication Critical patent/JP2004521108A5/ja
Application granted granted Critical
Publication of JP4115838B2 publication Critical patent/JP4115838B2/ja
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

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JP2002558467A 2001-01-18 2001-11-09 δＰＫＣの活性化および阻害のためのペプチド Expired - Fee Related JP4115838B2 (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US26206001P 2001-01-18 2001-01-18
PCT/US2001/047556 WO2002057413A2 (en) 2001-01-18 2001-11-09 Peptides for activation and inhibition of delta pkc

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2008048806A Division JP4592772B2 (ja) 2001-01-18 2008-02-28 δＰＫＣの活性化および阻害のためのペプチド

Publications (3)

Publication Number Publication Date
JP2004521108A JP2004521108A (ja) 2004-07-15
JP2004521108A5 true JP2004521108A5 (https=) 2006-01-05
JP4115838B2 JP4115838B2 (ja) 2008-07-09

Family

ID=22995990

Family Applications (2)

Application Number Title Priority Date Filing Date
JP2002558467A Expired - Fee Related JP4115838B2 (ja) 2001-01-18 2001-11-09 δＰＫＣの活性化および阻害のためのペプチド
JP2008048806A Expired - Fee Related JP4592772B2 (ja) 2001-01-18 2008-02-28 δＰＫＣの活性化および阻害のためのペプチド

Family Applications After (1)

Application Number Title Priority Date Filing Date
JP2008048806A Expired - Fee Related JP4592772B2 (ja) 2001-01-18 2008-02-28 δＰＫＣの活性化および阻害のためのペプチド

Country Status (6)

Country Link
US (5) US6855693B2 (https=)
EP (2) EP1351980B1 (https=)
JP (2) JP4115838B2 (https=)
AU (1) AU2002226061B2 (https=)
CA (1) CA2434643C (https=)
WO (1) WO2002057413A2 (https=)

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WO2005057213A1 (en) * 2003-12-09 2005-06-23 The Board Of Trustees Of The Leland Stanford Junior University Methods and compositions for modulating mitochondrial aldehyde dehydrogenase-2
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WO2005107789A1 (en) * 2004-04-30 2005-11-17 The Board Of Trustees Of The Leland Stanford Junior University Use of delta pkc peptides for modulation of reactive oxigen species
AU2005271477A1 (en) * 2004-08-02 2006-02-16 The Board Of Trustees Of The Leland Stanford Junior University Peptide sequence for modulation of delta protein kinase C
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US20060160062A1 (en) * 2005-01-14 2006-07-20 Young Lindon H Perfusion and/or preservation solution for organs
US20090186814A1 (en) * 2005-01-26 2009-07-23 Fumiaki Ikeno Methods and Compositions for Reducing Ischemia-Derived Microvascular Damage
WO2006095086A2 (fr) * 2005-03-07 2006-09-14 Laurence Faure Traçabilite des anomalies du cycle cellulaire ciblant l'oncologie et la neurodegenerescence.
US20070066526A1 (en) * 2005-09-02 2007-03-22 Daria Mochly-Rosen Method for reducing risk of and extent of injury due to stroke in hypertensive subjects
EP1934338A2 (en) 2005-09-19 2008-06-25 Kai Pharmaceuticals, Inc. Protein kinase c peptide modulators of angiogenesis
CA2632777C (en) * 2005-12-09 2019-08-20 Philadelphia College Of Osteopathic Medicine Organ preservation and/or perfusion
US20070148628A1 (en) * 2005-12-09 2007-06-28 Philadelphia College Of Osteopathic Medicine Organ preservation and/or perfusion
AU2007305268A1 (en) 2006-10-02 2008-04-10 The Board Of Trustees Of The Leland Stanford Junior University Peptides derived from the C2 domain of epsilon PKC, and use thereof
JP5645408B2 (ja) * 2006-11-16 2014-12-24 カイ ファーマシューティカルズ インコーポレーティッド 副甲状腺機能亢進症および高カルシウム血症性障害の治療のためのポリカチオン性カルシウムモジュレーターペプチド
WO2008080153A2 (en) * 2006-12-22 2008-07-03 The Children's Hospital Of Philadelphia A novel protein kinase c therapy for the treatment of acute lung injury
DK2617431T3 (en) * 2007-01-10 2017-07-10 Purdue Research Foundation Polypeptide inhibitors of HSP27 kinase and applications therefor
US20080293640A1 (en) * 2007-01-10 2008-11-27 Arizona Board of Regents, A body Corporate, of the State of Arizona, acting for and on behalf of Polypeptide inhibitors of HSP27 kinase and uses therefor
KR20090115852A (ko) * 2007-01-19 2009-11-09 카이 파마슈티컬즈 안정성 및 전달 효율을 증가시키기 위한 펩타이드 조성물의 변형
WO2008097563A1 (en) * 2007-02-06 2008-08-14 The Board Of Trustees Of The Leland Stanford Junior University Methods for maintaining blood-brain barrier integrity in hypertensive subjects using a delta-pkc inhibitor
KR100906153B1 (ko) 2007-07-04 2009-07-03 재단법인 한국원자력의학원 프로테인 카이네즈 씨 활성 저해용 단백질 및 이를포함하는 약제학적 조성물
WO2009021137A2 (en) * 2007-08-07 2009-02-12 Purdue Research Foundation Kinase inhibitors and uses thereof
CA2698013A1 (en) * 2007-08-27 2009-03-05 Kai Pharmaceuticals, Inc. Protein kinase c-d inhibitors that protect against cellular injury and inflammation and promote astrocyte proliferation
WO2009065080A1 (en) * 2007-11-16 2009-05-22 San Diego State University Research Foundation Compositions and method for manipulating pim-1 activity in circulatory system cells
US20090318351A1 (en) * 2008-03-12 2009-12-24 Kevin Grimes Method of treating acute st-elevation myocardial infarction with a delta pkc antagonist
WO2010019965A1 (en) * 2008-08-15 2010-02-18 The Board Of Trustees Of The Leland Stanford Junior University Compositions and methods for modulating epsilon protein kinase c-mediated cytoprotection
EP2378875B1 (en) 2008-12-10 2018-05-30 Purdue Research Foundation Cell-permeant peptide-based inhibitor of kinases
US9890195B2 (en) * 2009-07-27 2018-02-13 Purdue Research Foundation MK2 inhibitor compositions and methods to enhance neurite outgrowth, neuroprotection, and nerve regeneration
ES2729051T3 (es) 2009-07-29 2019-10-30 Kai Pharmaceuticals Inc Agentes terapéuticos para reducir los niveles de hormona paratiroidea
WO2011041385A2 (en) 2009-09-29 2011-04-07 Joslin Diabetes Center, Inc. Use of protein kinase c delta (pkcd) inhibitors to treat diabetes, obesity, and hepatic steatosis
CN103857405B (zh) 2011-06-08 2015-12-02 凯伊药品公司 用于调节血清磷的治疗剂
CN103998457B (zh) 2011-08-12 2017-09-22 利兰斯坦福初级大学信托董事会 用于特异性调节丙酮酸脱氢酶激酶的组合物和方法
WO2013134636A1 (en) 2012-03-09 2013-09-12 Purdue Research Foundation Compositions and methods for delivery of kinase inhibiting peptides
KR101611494B1 (ko) 2012-12-20 2016-04-12 한양대학교 산학협력단 ＰＫＣ－δ 검출용 폴리펩티드 및 이의 용도
US9987241B2 (en) 2014-09-25 2018-06-05 The Board Of Regents Of The University Of Oklahoma Enzyme conjugate and prodrug cancer therapy
CN106467493B (zh) * 2015-08-14 2021-04-23 苏州兰鼎生物制药有限公司 一种治疗缺血性脑卒中后遗症的化合物
WO2020032951A1 (en) 2018-08-09 2020-02-13 The Board Of Regents Of The University Of Oklahoma Antimalarial enzyme conjugates, kits containing same, and methods of producing and using same
KR20220159945A (ko) * 2020-03-31 2022-12-05 도레이 카부시키가이샤 화상 해석 장치, 화상 해석 장치의 제어 방법, 화상 해석 시스템, 및 화상 해석 시스템의 제어 방법

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US6664040B2 (en) 2000-05-23 2003-12-16 The Regents Of The University Of California Compositions and methods for delivery of a molecule into a cell
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US7265092B2 (en) 2004-09-30 2007-09-04 Kai Pharmaceuticals, Inc. Pharmaceutical formulation
US20060148700A1 (en) * 2004-11-10 2006-07-06 Daria Mochly-Rosen Methods and compositions for reducing injury to a transplanted organ
US7563772B2 (en) 2005-01-04 2009-07-21 The Board Of Trustees Of The Leland Stanford Junior University Methods of increasing cerebral blood flow
US20090186814A1 (en) 2005-01-26 2009-07-23 Fumiaki Ikeno Methods and Compositions for Reducing Ischemia-Derived Microvascular Damage
WO2008097563A1 (en) 2007-02-06 2008-08-14 The Board Of Trustees Of The Leland Stanford Junior University Methods for maintaining blood-brain barrier integrity in hypertensive subjects using a delta-pkc inhibitor
CA2698013A1 (en) 2007-08-27 2009-03-05 Kai Pharmaceuticals, Inc. Protein kinase c-d inhibitors that protect against cellular injury and inflammation and promote astrocyte proliferation

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