JP2004519452A5 - - Google Patents
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- Publication number
- JP2004519452A5 JP2004519452A5 JP2002554133A JP2002554133A JP2004519452A5 JP 2004519452 A5 JP2004519452 A5 JP 2004519452A5 JP 2002554133 A JP2002554133 A JP 2002554133A JP 2002554133 A JP2002554133 A JP 2002554133A JP 2004519452 A5 JP2004519452 A5 JP 2004519452A5
- Authority
- JP
- Japan
- Prior art keywords
- vaccine
- use according
- antigen
- compound
- polycationic compound
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 229960005486 vaccine Drugs 0.000 claims 9
- 150000001875 compounds Chemical class 0.000 claims 6
- 239000000427 antigen Substances 0.000 claims 4
- 102000036639 antigens Human genes 0.000 claims 4
- 108091007433 antigens Proteins 0.000 claims 4
- 239000013543 active substance Substances 0.000 claims 2
- 230000000694 effects Effects 0.000 claims 2
- 238000001727 in vivo Methods 0.000 claims 2
- 238000007918 intramuscular administration Methods 0.000 claims 2
- 238000007920 subcutaneous administration Methods 0.000 claims 2
- 206010061218 Inflammation Diseases 0.000 claims 1
- UGQMRVRMYYASKQ-KQYNXXCUSA-N Inosine Chemical compound O[C@@H]1[C@H](O)[C@@H](CO)O[C@H]1N1C2=NC=NC(O)=C2N=C1 UGQMRVRMYYASKQ-KQYNXXCUSA-N 0.000 claims 1
- 229930010555 Inosine Natural products 0.000 claims 1
- 230000003111 delayed effect Effects 0.000 claims 1
- 230000002163 immunogen Effects 0.000 claims 1
- 230000006698 induction Effects 0.000 claims 1
- 230000004054 inflammatory process Effects 0.000 claims 1
- 229960003786 inosine Drugs 0.000 claims 1
- 150000007523 nucleic acids Chemical class 0.000 claims 1
- 102000039446 nucleic acids Human genes 0.000 claims 1
- 108020004707 nucleic acids Proteins 0.000 claims 1
- 230000000144 pharmacologic effect Effects 0.000 claims 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| PCT/EP2001/000087 WO2001054720A1 (en) | 2000-01-28 | 2001-01-05 | Pharmaceutical composition for immunomodulation and preparation of vaccines comprising an antigen and an immunogenic oligodeoxynucleotide and a polycationic polymer as adjuvants |
| AT6722001 | 2001-04-25 | ||
| PCT/EP2002/000062 WO2002053184A2 (en) | 2001-01-05 | 2002-01-07 | Uses for polycationic compounds as vaccine adjuvants |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004519452A JP2004519452A (ja) | 2004-07-02 |
| JP2004519452A5 true JP2004519452A5 (enExample) | 2005-12-22 |
Family
ID=25608382
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002554133A Pending JP2004519452A (ja) | 2001-01-05 | 2002-01-07 | ポリカチオン性化合物の用途 |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP1347775B1 (enExample) |
| JP (1) | JP2004519452A (enExample) |
| CA (1) | CA2433794A1 (enExample) |
| WO (1) | WO2002053184A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP1347775B1 (en) | 2001-01-05 | 2016-11-30 | Valneva Austria GmbH | Uses for polycationic compounds as vaccine adjuvants |
| EP1608402B1 (en) * | 2003-03-24 | 2010-10-20 | Intercell AG | Improved vaccines |
| WO2011101465A1 (en) | 2010-02-19 | 2011-08-25 | Intercell Ag | Ic31 nanoparticles |
| KR101586200B1 (ko) * | 2014-12-31 | 2016-01-18 | 성균관대학교산학협력단 | 면역자극 조성물, 이의 제조 방법, 및 이를 포함하는 면역요법 조성물 |
| US20230210763A1 (en) * | 2019-09-19 | 2023-07-06 | Amw Gmbh | Extruded depot form for controlled active substance release |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB744988A (en) * | 1952-01-31 | 1956-02-15 | Allen & Hanburys Ltd | Improvements in preparations of insulin |
| GB8921470D0 (en) * | 1989-09-22 | 1989-11-08 | Peptide Technology Ltd | Vaccines |
| AU653771B2 (en) * | 1991-01-03 | 1994-10-13 | Alkermes Controlled Therapeutics, Inc. | Stabilization of proteins by cationic biopolymers |
| CO4600681A1 (es) * | 1996-02-24 | 1998-05-08 | Boehringer Ingelheim Pharma | Composicion farmaceutica para la modulacion inmunitaria |
| DE60003151T2 (de) * | 1999-01-13 | 2004-04-08 | Johns Hopkins University School Of Medicine | Genetische immunisierung mit gleichzeitiger verabreichung von nukleinsäuren und zytokinen |
| PL203951B1 (pl) * | 1999-04-19 | 2009-11-30 | Smithkline Beecham Biolog | Kompozycja adiuwantowa, kompozycja szczepionki oraz sposób jej wytwarzania, szczepionka oraz zastosowanie |
| AT408721B (de) * | 1999-10-01 | 2002-02-25 | Cistem Biotechnologies Gmbh | Pharmazeutische zusammensetzung enthaltend ein antigen |
| AT409085B (de) | 2000-01-28 | 2002-05-27 | Cistem Biotechnologies Gmbh | Pharmazeutische zusammensetzung zur immunmodulation und herstellung von vakzinen |
| HU228264B1 (en) * | 2000-06-08 | 2013-02-28 | Intercell Ag | Immunostimulatory oligodeoxynucleotides |
| AT410635B (de) * | 2000-10-18 | 2003-06-25 | Cistem Biotechnologies Gmbh | Vakzin-zusammensetzung |
| EP1347775B1 (en) | 2001-01-05 | 2016-11-30 | Valneva Austria GmbH | Uses for polycationic compounds as vaccine adjuvants |
-
2002
- 2002-01-07 EP EP02700194.0A patent/EP1347775B1/en not_active Expired - Lifetime
- 2002-01-07 JP JP2002554133A patent/JP2004519452A/ja active Pending
- 2002-01-07 WO PCT/EP2002/000062 patent/WO2002053184A2/en not_active Ceased
- 2002-01-07 CA CA002433794A patent/CA2433794A1/en not_active Abandoned
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