JP2004513615A5 - - Google Patents
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- JP2004513615A5 JP2004513615A5 JP2002504957A JP2002504957A JP2004513615A5 JP 2004513615 A5 JP2004513615 A5 JP 2004513615A5 JP 2002504957 A JP2002504957 A JP 2002504957A JP 2002504957 A JP2002504957 A JP 2002504957A JP 2004513615 A5 JP2004513615 A5 JP 2004513615A5
- Authority
- JP
- Japan
- Prior art keywords
- polypeptide
- composition
- lung cancer
- seq
- amino acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 229920001184 polypeptide Polymers 0.000 description 5
- 206010058467 Lung neoplasm malignant Diseases 0.000 description 3
- 201000005202 lung cancer Diseases 0.000 description 3
- 229920000023 polynucleotide Polymers 0.000 description 3
- 239000002157 polynucleotide Substances 0.000 description 3
- 125000003275 alpha amino acid group Chemical group 0.000 description 2
- 102000037240 fusion proteins Human genes 0.000 description 2
- 108020001507 fusion proteins Proteins 0.000 description 2
- 238000009007 Diagnostic Kit Methods 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000028993 immune response Effects 0.000 description 1
- 230000003344 immunostimulant Effects 0.000 description 1
- 239000003022 immunostimulating agent Substances 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 230000004936 stimulating Effects 0.000 description 1
Description
【特許請求の範囲】
【請求項1】 配列番号363に示すアミノ酸配列からなる単離されたポリペプチド、又は配列番号363に示すアミノ酸配列の全長に対し少なくとも90%の配列同一性を示す免疫学的反応性のその変異体。
【請求項2】 請求項1に記載のポリペプチドをコードする単離されたポリヌクレオチド。
【請求項3】 発現制御配列と機能的に連結された請求項2に記載のポリヌクレオチドを含む発現ベクター。
【請求項4】 請求項3に記載の発現ベクターで形質転換又はトランスフェクトした宿主細胞。
【請求項5】 請求項1に記載のポリペプチドを含む融合タンパク質。
【請求項6】 肺癌患者における免疫応答の刺激に使用するための組成物であって、生理学的に受容可能なキャリア及び免疫刺激剤からなる群から選択される第1の成分と、以下の(a)〜(c):
(a) 請求項1に記載のポリペプチド
(b) 請求項2に記載のポリヌクレオチド
(c) 請求項5に記載の融合タンパク質
よりなる群から選択される第2の成分とを含む組成物。
【請求項7】 患者の肺癌の治療に使用するための請求項6に記載の組成物。
【請求項8】 肺癌を治療するための医薬の製造のための請求項6に記載の組成物の使用。
【請求項9】 請求項1に記載のポリペプチドを含む診断キット。
【請求項1】 配列番号363に示すアミノ酸配列からなる単離されたポリペプチド、又は配列番号363に示すアミノ酸配列の全長に対し少なくとも90%の配列同一性を示す免疫学的反応性のその変異体。
【請求項2】 請求項1に記載のポリペプチドをコードする単離されたポリヌクレオチド。
【請求項3】 発現制御配列と機能的に連結された請求項2に記載のポリヌクレオチドを含む発現ベクター。
【請求項4】 請求項3に記載の発現ベクターで形質転換又はトランスフェクトした宿主細胞。
【請求項5】 請求項1に記載のポリペプチドを含む融合タンパク質。
【請求項6】 肺癌患者における免疫応答の刺激に使用するための組成物であって、生理学的に受容可能なキャリア及び免疫刺激剤からなる群から選択される第1の成分と、以下の(a)〜(c):
(a) 請求項1に記載のポリペプチド
(b) 請求項2に記載のポリヌクレオチド
(c) 請求項5に記載の融合タンパク質
よりなる群から選択される第2の成分とを含む組成物。
【請求項7】 患者の肺癌の治療に使用するための請求項6に記載の組成物。
【請求項8】 肺癌を治療するための医薬の製造のための請求項6に記載の組成物の使用。
【請求項9】 請求項1に記載のポリペプチドを含む診断キット。
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/606,421 US6531315B1 (en) | 1998-03-18 | 2000-06-28 | Compositions and methods for the therapy and diagnosis of lung cancer |
US09/630,940 US6737514B1 (en) | 1998-12-22 | 2000-08-02 | Compositions and methods for the therapy and diagnosis of lung cancer |
US09/643,597 US6426072B1 (en) | 2000-08-02 | 2000-08-21 | Compositions and methods for the therapy and diagnosis of lung cancer |
US66278600A | 2000-09-15 | 2000-09-15 | |
US68569600A | 2000-10-09 | 2000-10-09 | |
US09/735,705 US7049063B2 (en) | 1998-03-18 | 2000-12-12 | Methods for diagnosis of lung cancer |
US09/850,716 US20020115139A1 (en) | 2000-12-12 | 2001-05-07 | Compositions and methods for the therapy and diagnosis of lung cancer |
PCT/US2001/021065 WO2002000174A2 (en) | 2000-06-28 | 2001-06-28 | Compositions and methods for the therapy and diagnosis of lung cancer |
Publications (2)
Publication Number | Publication Date |
---|---|
JP2004513615A JP2004513615A (ja) | 2004-05-13 |
JP2004513615A5 true JP2004513615A5 (ja) | 2008-08-14 |
Family
ID=27569853
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP2002504957A Pending JP2004513615A (ja) | 2000-06-28 | 2001-06-28 | 肺癌の治療および診断のための組成物および方法 |
Country Status (7)
Country | Link |
---|---|
EP (2) | EP1319069B1 (ja) |
JP (1) | JP2004513615A (ja) |
AR (1) | AR029540A1 (ja) |
AT (1) | ATE396265T1 (ja) |
AU (1) | AU2001273149A1 (ja) |
DE (1) | DE60134158D1 (ja) |
WO (1) | WO2002000174A2 (ja) |
Families Citing this family (9)
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---|---|---|---|---|
US20020147143A1 (en) * | 1998-03-18 | 2002-10-10 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US7258860B2 (en) | 1998-03-18 | 2007-08-21 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US20040235072A1 (en) * | 1998-03-18 | 2004-11-25 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
US7579160B2 (en) | 1998-03-18 | 2009-08-25 | Corixa Corporation | Methods for the detection of cervical cancer |
US20030236209A1 (en) * | 1998-03-18 | 2003-12-25 | Corixa Corporation | Compositions and methods for the therapy and diagnosis of lung cancer |
EP1679382A3 (en) * | 2002-03-29 | 2008-03-19 | Ortho-Clinical Diagnostics, Inc. | Panel of nucleic acid sequences for cancer diagnosis |
WO2006031221A1 (en) * | 2004-09-13 | 2006-03-23 | Government Of The United States Of America, Represented By The Secretary, Department Of Health And Human Services | Compositions comprising t cell receptors and methods of use thereof |
JP5095416B2 (ja) | 2005-12-06 | 2012-12-12 | 協和発酵キリン株式会社 | 抗perp遺伝子組換え抗体 |
CA3025648A1 (en) * | 2016-05-27 | 2017-11-30 | Etubics Corporation | Neoepitope vaccine compositions and methods of use thereof |
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2001
- 2001-06-28 EP EP01952390A patent/EP1319069B1/en not_active Expired - Lifetime
- 2001-06-28 DE DE60134158T patent/DE60134158D1/de not_active Expired - Fee Related
- 2001-06-28 AR ARP010103097A patent/AR029540A1/es unknown
- 2001-06-28 AU AU2001273149A patent/AU2001273149A1/en not_active Abandoned
- 2001-06-28 JP JP2002504957A patent/JP2004513615A/ja active Pending
- 2001-06-28 WO PCT/US2001/021065 patent/WO2002000174A2/en active Application Filing
- 2001-06-28 AT AT01952390T patent/ATE396265T1/de not_active IP Right Cessation
- 2001-06-28 EP EP08009325A patent/EP1961819A3/en not_active Withdrawn
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