JP2004512258A - 生物系における細胞応答の調節のための方法および試薬 - Google Patents

生物系における細胞応答の調節のための方法および試薬 Download PDF

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JP2004512258A
JP2004512258A JP2001569247A JP2001569247A JP2004512258A JP 2004512258 A JP2004512258 A JP 2004512258A JP 2001569247 A JP2001569247 A JP 2001569247A JP 2001569247 A JP2001569247 A JP 2001569247A JP 2004512258 A JP2004512258 A JP 2004512258A
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ligand
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multivalent ligand
multivalent
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キースリング, ローラ エル.
ストロング, ローラ イー.
ゲストウィッキ, ジェイソン イー.
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ウィスコンシン アルムニ リサーチ ファンデイション
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/74Synthetic polymeric materials
    • A61K31/785Polymers containing nitrogen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/17Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • A61K38/177Receptors; Cell surface antigens; Cell surface determinants
    • A61K38/178Lectin superfamily, e.g. selectins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/385Haptens or antigens, bound to carriers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/02Immunomodulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells

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  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
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  • Nanotechnology (AREA)
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  • Materials Engineering (AREA)
  • Biotechnology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Composite Materials (AREA)
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  • Food Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Pathology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
JP2001569247A 2000-03-21 2001-03-21 生物系における細胞応答の調節のための方法および試薬 Withdrawn JP2004512258A (ja)

Applications Claiming Priority (2)

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US19101400P 2000-03-21 2000-03-21
PCT/US2001/009174 WO2001071309A2 (en) 2000-03-21 2001-03-21 Methods and reagents for regulation of cellular responses in biological systems

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JP2004512258A true JP2004512258A (ja) 2004-04-22
JP2004512258A5 JP2004512258A5 (https=) 2008-05-22

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US (2) US20030125262A1 (https=)
EP (1) EP1334118A4 (https=)
JP (1) JP2004512258A (https=)
AU (2) AU2001281499B2 (https=)
CA (1) CA2403669A1 (https=)
WO (1) WO2001071309A2 (https=)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006347908A (ja) * 2005-06-14 2006-12-28 National Institute Of Advanced Industrial & Technology シアル酸含有3糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20040248801A1 (en) * 2000-03-21 2004-12-09 Kiessling Laura L. Methods and reagents for regulation of cellular responses in biological systems
JP2004512258A (ja) * 2000-03-21 2004-04-22 ウィスコンシン アルムニ リサーチ ファンデイション 生物系における細胞応答の調節のための方法および試薬
WO2004100997A2 (en) 2003-05-12 2004-11-25 Affymax, Inc. Spacer moiety for poly(ethylene glycol) -modified peptides
JP2007530440A (ja) * 2003-05-12 2007-11-01 アフィーマックス・インコーポレイテッド 新規ポリ(エチレングリコール)修飾化合物およびその用途
SI1625156T1 (sl) * 2003-05-12 2013-02-28 Affymax, Inc. Peptidi, ki se veĹľejo k eritropoetinskemu receptorju
JP4266028B2 (ja) 2003-05-12 2009-05-20 アフィーマックス・インコーポレイテッド エリスロポエチン受容体に結合する新規ペプチド
WO2006062685A2 (en) * 2004-11-11 2006-06-15 Affymax, Inc. Novel peptides that bind to the erythropoietin receptor
EA200700990A1 (ru) * 2004-11-11 2008-04-28 Афимакс, Инк. Новые пептиды, которые связывают рецептор эритропоэтина
GB0426822D0 (en) * 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
GB0426823D0 (en) * 2004-12-07 2005-01-12 Precisense As Sensor for detection of glucose
US7550433B2 (en) * 2005-06-03 2009-06-23 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US8324159B2 (en) * 2005-06-03 2012-12-04 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
US7919461B2 (en) 2005-06-03 2011-04-05 Affymax, Inc. Erythropoietin receptor peptide formulations and uses
EP2015784A4 (en) * 2006-05-03 2012-12-26 Wisconsin Alumni Res Found USING RING OPENING METATHESISPOLYMERIZATION SYNTHETIZED MAGNETIC RESONANCE GRAIN
WO2008116293A1 (en) * 2007-03-23 2008-10-02 The Governors Of The University Of Alberta Multivalent heterobifunctional polymers and methods of their use
US9029332B2 (en) 2010-12-15 2015-05-12 The Research Foundation For The State University Of New York Cross-linked peptides and proteins, methods of making same, and uses thereof
US20140350370A1 (en) * 2013-04-08 2014-11-27 The Texas A&M University System Glucose sensing assay
WO2018200951A1 (en) * 2017-04-28 2018-11-01 Tran David T Multi-targeted multi-valent ligand-drug particles for the treatment and prevention of diseases and conditions

Family Cites Families (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4427660A (en) * 1982-03-03 1984-01-24 Research Corporation Formyl-methionyl chemotatic peptide antibiotic conjugates useful in treating infections
US4883851A (en) * 1988-07-25 1989-11-28 California Institute Of Technology Ring opening metathesis polymerization of strained cyclic ethers
US5100972A (en) * 1990-07-16 1992-03-31 General Electric Company Cycloalkene terminated polyarylene ether
US5641622A (en) * 1990-09-13 1997-06-24 Baxter International Inc. Continuous centrifugation process for the separation of biological components from heterogeneous cell populations
US5312940A (en) * 1992-04-03 1994-05-17 California Institute Of Technology Ruthenium and osmium metal carbene complexes for olefin metathesis polymerization
US5710298A (en) * 1992-04-03 1998-01-20 California Institute Of Technology Method of preparing ruthenium and osmium carbene complexes
JP3067031B2 (ja) * 1992-04-03 2000-07-17 カリフォルニア インスティチュート オブ テクノロジー オレフィンメタセシス重合方法
US5599912A (en) * 1993-09-10 1997-02-04 Coretech, Inc. Compounds and methods for suppressing an immune response to sulfomethoxozale containing substances
US5587442A (en) * 1994-12-23 1996-12-24 Kiessling; Laura L. Polyglycomers
US5831108A (en) * 1995-08-03 1998-11-03 California Institute Of Technology High metathesis activity ruthenium and osmium metal carbene complexes
US6060570A (en) * 1996-08-12 2000-05-09 Bp Amoco Corporation Process for preparation of addition products of difunctional telechelic polyolefins from cyclic olefins by olefin metathesis reaction
US6080826A (en) * 1997-01-06 2000-06-27 California Institute Of Technology Template-directed ring-closing metathesis and ring-opening metathesis polymerization of functionalized dienes
US5889128A (en) * 1997-04-11 1999-03-30 Massachusetts Institute Of Technology Living olefin polymerization processes
DE19742980A1 (de) * 1997-09-29 1999-04-01 Espe Dental Ag Dentalmassen auf der Basis von ROMP-Oligomeren oder -Polymeren
US6121236A (en) * 1998-03-24 2000-09-19 The Children's Medical Center Corporation Multivalent ligands which modulate angiogenesis
US6437119B1 (en) * 1998-05-07 2002-08-20 William Lawrence Truett Compounds formed from two or three antibiotics and their processes of preparation
US6280527B1 (en) * 1998-06-12 2001-08-28 International Business Machines Corporation Aqueous quaternary ammonium hydroxide as a screening mask cleaner
US6271315B1 (en) * 1999-06-17 2001-08-07 Wisconsin Alumni Research Foundation Methods for making multivalent arrays
US6291616B1 (en) * 1999-06-17 2001-09-18 Wisconsin Alumni Research Foundation Methods and reagents for capping ruthenium or osmium carbene-catalyzed ROMP products
HUP9902217A3 (en) * 1999-06-29 2002-07-29 Szegoe Peter Polycation based bioconjugates and process for producing thereof
GB9916235D0 (en) * 1999-07-09 1999-09-15 Univ Durham Process for polymerisation of olefins and novel polymerisable olefins
US20040248801A1 (en) * 2000-03-21 2004-12-09 Kiessling Laura L. Methods and reagents for regulation of cellular responses in biological systems
JP2004512258A (ja) * 2000-03-21 2004-04-22 ウィスコンシン アルムニ リサーチ ファンデイション 生物系における細胞応答の調節のための方法および試薬
EP2015784A4 (en) * 2006-05-03 2012-12-26 Wisconsin Alumni Res Found USING RING OPENING METATHESISPOLYMERIZATION SYNTHETIZED MAGNETIC RESONANCE GRAIN

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006347908A (ja) * 2005-06-14 2006-12-28 National Institute Of Advanced Industrial & Technology シアル酸含有3糖化合物、それを用いるサーズウイルスまたはサーズスパイク蛋白質の検出

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EP1334118A4 (en) 2005-10-05
CA2403669A1 (en) 2001-09-27
US20030125262A1 (en) 2003-07-03
WO2001071309A2 (en) 2001-09-27
AU8149901A (en) 2001-10-03
EP1334118A2 (en) 2003-08-13
AU2001281499B2 (en) 2007-01-04
WO2001071309A3 (en) 2003-05-15
US20070270351A1 (en) 2007-11-22

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