JP2004510749A - No阻害またはtnf阻害に関連した疾病の治療におけるpparデルタ活性化因子の使用 - Google Patents

No阻害またはtnf阻害に関連した疾病の治療におけるpparデルタ活性化因子の使用 Download PDF

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JP2004510749A
JP2004510749A JP2002532257A JP2002532257A JP2004510749A JP 2004510749 A JP2004510749 A JP 2004510749A JP 2002532257 A JP2002532257 A JP 2002532257A JP 2002532257 A JP2002532257 A JP 2002532257A JP 2004510749 A JP2004510749 A JP 2004510749A
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ppardelta
tnf
synthase
methyl
disease
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JP2002532257A
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JP2004510749A5 (https=
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バカン,ケヴィン,ウィリアム
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Glaxo Group Ltd
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Glaxo Group Ltd
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/42Oxazoles
    • A61K31/4211,3-Oxazoles, e.g. pemoline, trimethadione
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    • A61K31/33Heterocyclic compounds
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    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
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JP2002532257A 2000-10-05 2001-10-02 No阻害またはtnf阻害に関連した疾病の治療におけるpparデルタ活性化因子の使用 Pending JP2004510749A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0024362.6A GB0024362D0 (en) 2000-10-05 2000-10-05 Medicaments
PCT/GB2001/004370 WO2002028433A2 (en) 2000-10-05 2001-10-02 Use of a ppar delta activator in the treatment of diseases related to no inhibit ion or tnf inhibition

Publications (2)

Publication Number Publication Date
JP2004510749A true JP2004510749A (ja) 2004-04-08
JP2004510749A5 JP2004510749A5 (https=) 2005-12-22

Family

ID=9900710

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2002532257A Pending JP2004510749A (ja) 2000-10-05 2001-10-02 No阻害またはtnf阻害に関連した疾病の治療におけるpparデルタ活性化因子の使用

Country Status (6)

Country Link
US (1) US20040029938A1 (https=)
EP (1) EP1324773A2 (https=)
JP (1) JP2004510749A (https=)
AU (1) AU2001292044A1 (https=)
GB (1) GB0024362D0 (https=)
WO (1) WO2002028433A2 (https=)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BR0212512A (pt) 2001-09-14 2004-10-26 Tularik Inc Composto, composição farmacêutica e métodos para tratar um distúrbio, condição ou doença, elevar os nìveis do colesterol hdl, reduzir os nìveis de triglicerìdeo, tratar diabete, diminuir a resistência à insulina ou diminuir a pressão arterial e modular a ppardelta
US20070037882A1 (en) * 2003-04-22 2007-02-15 Astellas Pharma Inc. Remedy for cerebral neurodegenerative diseases using ppar agonist
CA2525764C (en) * 2003-05-20 2012-07-17 Novartis Ag N-acyl nitrogen heterocycles as ligands of peroxisome proliferator-activated receptors
RU2005141516A (ru) 2003-06-06 2007-07-20 Ф.Хоффманн-Ля Рош Аг (Ch) Производные анилина
KR100796093B1 (ko) 2003-07-02 2008-01-21 에프. 호프만-라 로슈 아게 티아졸 고리로 치환된 인돌릴 유도체 및 ppar조절제로서 그의 용도
JP2007530703A (ja) * 2004-04-01 2007-11-01 アベンティス・ファーマスーティカルズ・インコーポレイテツド Msおよびその他の脱髄疾患を治療するためのペルオキシソーム増殖因子活性化受容体デルタアゴニストの使用
US7126825B2 (en) * 2004-12-07 2006-10-24 Cleavage Enterprise Co., Ltd. Combined chip/heat-dissipating metal plate and method for manufacturing the same
CN102724978A (zh) * 2009-08-14 2012-10-10 塞伦尼斯治疗公司 用于治疗或预防炎症或能量代谢/产生相关疾病的PPARδ配体的用途

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1997028149A1 (en) * 1996-02-02 1997-08-07 Merck & Co., Inc. Method for raising hdl cholesterol levels
CA2295930C (en) * 1997-07-24 2010-12-14 Yamanouchi Pharmaceutical Co., Ltd. Pharmaceutical compositions having cholesterol-lowering effect
GB9914977D0 (en) * 1999-06-25 1999-08-25 Glaxo Group Ltd Chemical compounds
EP1170008A1 (en) * 2000-07-07 2002-01-09 Chemotherapeutisches Forschungsinstitut Georg-Speyer-Haus Valproic acid and derivatives thereof as histone deacetylase inhibitors

Also Published As

Publication number Publication date
GB0024362D0 (en) 2000-11-22
US20040029938A1 (en) 2004-02-12
EP1324773A2 (en) 2003-07-09
AU2001292044A1 (en) 2002-04-15
WO2002028433A3 (en) 2002-08-15
WO2002028433A2 (en) 2002-04-11

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