JP2004506086A - インフルエンザ菌感染症の予防用ワクチンとしてのインフルエンザ菌リポ多糖内部コアオリゴ糖エピトープ - Google Patents

インフルエンザ菌感染症の予防用ワクチンとしてのインフルエンザ菌リポ多糖内部コアオリゴ糖エピトープ Download PDF

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Publication number
JP2004506086A
JP2004506086A JP2002521535A JP2002521535A JP2004506086A JP 2004506086 A JP2004506086 A JP 2004506086A JP 2002521535 A JP2002521535 A JP 2002521535A JP 2002521535 A JP2002521535 A JP 2002521535A JP 2004506086 A JP2004506086 A JP 2004506086A
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JP
Japan
Prior art keywords
lps
haemophilus influenzae
lipopolysaccharide
strain
moiety
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JP2002521535A
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Japanese (ja)
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JP2004506086A5 (enExample
Inventor
ジェームズ、シー．リチャーズ
アンドリュー、コックス
リチャード、モクソン
デレック、フッド
エルク、ケイ．エイチ．シュウィーダ
マーティン、マンソン
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Sanofi Pasteur Ltd
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Aventis Pasteur Ltd
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Publication of JP2004506086A publication Critical patent/JP2004506086A/ja
Publication of JP2004506086A5 publication Critical patent/JP2004506086A5/ja
Pending legal-status Critical Current

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1242—Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
JP2002521535A 2000-08-25 2001-08-27 インフルエンザ菌感染症の予防用ワクチンとしてのインフルエンザ菌リポ多糖内部コアオリゴ糖エピトープ Pending JP2004506086A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US22785000P 2000-08-25 2000-08-25
PCT/CA2001/001225 WO2002016440A2 (en) 2000-08-25 2001-08-27 Haemophilus influenzae lipopolysaccharide inner-core oligosaccharide epitopes as vaccines for the prevention of haemophilus influenzae infections

Publications (2)

Publication Number Publication Date
JP2004506086A true JP2004506086A (ja) 2004-02-26
JP2004506086A5 JP2004506086A5 (enExample) 2008-10-16

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Family Applications (1)

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JP2002521535A Pending JP2004506086A (ja) 2000-08-25 2001-08-27 インフルエンザ菌感染症の予防用ワクチンとしてのインフルエンザ菌リポ多糖内部コアオリゴ糖エピトープ

Country Status (9)

Country Link
US (1) US7364739B2 (enExample)
EP (1) EP1313771B1 (enExample)
JP (1) JP2004506086A (enExample)
AT (1) ATE357461T1 (enExample)
AU (1) AU2001285633A1 (enExample)
CA (1) CA2420477A1 (enExample)
DE (1) DE60127421T8 (enExample)
ES (1) ES2284681T3 (enExample)
WO (1) WO2002016440A2 (enExample)

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007537307A (ja) * 2004-05-14 2007-12-20 ナショナル リサーチ カウンセル カナダ 多種ワクチン候補としての保存された内側コアリポ多糖体エピトープ：アクチノバシラス・プレウロニューモニー、マンヘイミア・ヘモリティカ及びパスツレラ・マルトシダを含む畜獣の病原菌によって起きる病気の予防のためのワクチン候補としての内核リポ多糖体エピトープ
JP2008125425A (ja) * 2006-11-20 2008-06-05 Osaka Univ 核酸の増幅反応に用いる繰返し配列結合プライマー及びその利用

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7527797B1 (en) 2000-09-01 2009-05-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Vibrio cholerae 0139 conjugate vaccines
US8795680B2 (en) * 2006-07-21 2014-08-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for conjugation of oligosaccharides or polysaccharides to protein carriers through oxime linkages via 3-deoxy-D-manno-octulsonic acid
CA2680038A1 (en) * 2007-03-08 2008-09-12 The Governors Of The University Of Alberta Bacterial endotoxin for the prevention of metabolic disorders and bacterial infections
WO2016007891A1 (en) * 2014-07-10 2016-01-14 University Of Iowa Research Foundation Vaccine for nontypeable haemophilus influenzae

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000036419A1 (en) * 1998-12-15 2000-06-22 Exiqon A/S Coupling of lipopolysaccharide-derived carbohydrates onto solid surfaces

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0347425B1 (en) 1987-03-02 1995-12-27 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
US5204098A (en) * 1988-02-16 1993-04-20 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-protein conjugates
ZA894589B (en) * 1989-02-09 1991-02-27 K Sudan Krishan Semi-flexible or flexible phenolic foam
CA2076753A1 (en) 1990-02-26 1991-08-27 Anthony J. Radford Shuttle plasmid for escherichia coli and mycobacteria
GB9015888D0 (en) 1990-07-19 1990-09-05 Smithkline Biolog Vectors
US5153312A (en) * 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
WO1992011361A1 (en) 1990-12-18 1992-07-09 The General Hospital Corporation Improved vaccines
EP0587775A4 (en) 1991-06-06 1994-11-02 Medimmune Inc INDUCTION OF THE CTL RESPONSE BY FOREIGN ANTIGENS EXPRESSED IN MYCOBACTERIES.
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
WO1994016737A1 (en) 1993-01-26 1994-08-04 Weiner David B Compositions and methods for delivery of genetic material
GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
US20030072774A1 (en) 1994-06-10 2003-04-17 Diane M. Gajewczyk Proteinaceous adjuvants
US6019982A (en) 1994-08-26 2000-02-01 The Administrators Of The Tulane Educational Fund Mutant enterotoxin effective as a non-toxic oral adjuvant
US5527928A (en) * 1994-09-30 1996-06-18 Nantz; Michael H. Cationic transport reagents
US6207157B1 (en) * 1996-04-23 2001-03-27 The United States Of America As Represented By The Department Of Health And Human Services Conjugate vaccine for nontypeable Haemophilus influenzae
CA2264970A1 (en) 1998-03-10 1999-09-10 American Cyanamid Company Antigenic conjugates of conserved lipolysaccharides of gram negative bacteria
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
DE19844191A1 (de) 1998-09-28 2000-03-30 Pharma Zentrale Gmbh Lipopolysaccharide aus Escherichia coli
CA2374235A1 (en) 1999-05-18 2000-11-23 University Of Iowa Research Foundation Production of complex carbohydrates

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000036419A1 (en) * 1998-12-15 2000-06-22 Exiqon A/S Coupling of lipopolysaccharide-derived carbohydrates onto solid surfaces

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2007537307A (ja) * 2004-05-14 2007-12-20 ナショナル リサーチ カウンセル カナダ 多種ワクチン候補としての保存された内側コアリポ多糖体エピトープ：アクチノバシラス・プレウロニューモニー、マンヘイミア・ヘモリティカ及びパスツレラ・マルトシダを含む畜獣の病原菌によって起きる病気の予防のためのワクチン候補としての内核リポ多糖体エピトープ
JP2008125425A (ja) * 2006-11-20 2008-06-05 Osaka Univ 核酸の増幅反応に用いる繰返し配列結合プライマー及びその利用

Also Published As

Publication number Publication date
AU2001285633A1 (en) 2002-03-04
EP1313771B1 (en) 2007-03-21
EP1313771A2 (en) 2003-05-28
US7364739B2 (en) 2008-04-29
WO2002016440A8 (en) 2002-11-14
ES2284681T3 (es) 2007-11-16
DE60127421T2 (de) 2007-11-29
WO2002016440A9 (en) 2004-05-13
CA2420477A1 (en) 2002-02-28
WO2002016440A3 (en) 2002-06-06
DE60127421D1 (de) 2007-05-03
WO2002016440A2 (en) 2002-02-28
DE60127421T8 (de) 2008-08-28
US20050153057A1 (en) 2005-07-14
ATE357461T1 (de) 2007-04-15

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