DE60127421T8 - Innen-kern oligosaccharide epitopes aus lipopolysacchariden von haemophilus influenza als vakzinen in der prophylaktischen behandlung von haemophilus influenzae infektionen - Google Patents

Innen-kern oligosaccharide epitopes aus lipopolysacchariden von haemophilus influenza als vakzinen in der prophylaktischen behandlung von haemophilus influenzae infektionen Download PDF

Info

Publication number
DE60127421T8
DE60127421T8 DE60127421T DE60127421T DE60127421T8 DE 60127421 T8 DE60127421 T8 DE 60127421T8 DE 60127421 T DE60127421 T DE 60127421T DE 60127421 T DE60127421 T DE 60127421T DE 60127421 T8 DE60127421 T8 DE 60127421T8
Authority
DE
Germany
Prior art keywords
vaccines
haemophilus influenzae
lipopolysaccharide
haemophilus
relates
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE60127421T
Other languages
German (de)
English (en)
Other versions
DE60127421T2 (de
DE60127421D1 (de
Inventor
James C. Ottawa RICHARDS
Andrew Gloucester COX
Richard Moxon
Derek Institute of HOOD
Elke K. H. Schweda
Martin Mansson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
National Research Council of Canada
University of Oxford
SCHWEDA ELKE
Original Assignee
National Research Council of Canada
University of Oxford
SCHWEDA ELKE
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by National Research Council of Canada, University of Oxford, SCHWEDA ELKE filed Critical National Research Council of Canada
Publication of DE60127421D1 publication Critical patent/DE60127421D1/de
Publication of DE60127421T2 publication Critical patent/DE60127421T2/de
Application granted granted Critical
Publication of DE60127421T8 publication Critical patent/DE60127421T8/de
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1203—Gram-negative bacteria
    • C07K16/1242—Gram-negative bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/16—Antivirals for RNA viruses for influenza or rhinoviruses
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Communicable Diseases (AREA)
  • Pulmonology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Virology (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Polymers & Plastics (AREA)
  • Immunology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Materials Engineering (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
DE60127421T 2000-08-25 2001-08-27 Innen-kern oligosaccharide epitopes aus lipopolysacchariden von haemophilus influenza als vakzinen in der prophylaktischen behandlung von haemophilus influenzae infektionen Expired - Fee Related DE60127421T8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US22785000P 2000-08-25 2000-08-25
US227850P 2000-08-25
PCT/CA2001/001225 WO2002016440A2 (en) 2000-08-25 2001-08-27 Haemophilus influenzae lipopolysaccharide inner-core oligosaccharide epitopes as vaccines for the prevention of haemophilus influenzae infections

Publications (3)

Publication Number Publication Date
DE60127421D1 DE60127421D1 (de) 2007-05-03
DE60127421T2 DE60127421T2 (de) 2007-11-29
DE60127421T8 true DE60127421T8 (de) 2008-08-28

Family

ID=22854724

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60127421T Expired - Fee Related DE60127421T8 (de) 2000-08-25 2001-08-27 Innen-kern oligosaccharide epitopes aus lipopolysacchariden von haemophilus influenza als vakzinen in der prophylaktischen behandlung von haemophilus influenzae infektionen

Country Status (9)

Country Link
US (1) US7364739B2 (enExample)
EP (1) EP1313771B1 (enExample)
JP (1) JP2004506086A (enExample)
AT (1) ATE357461T1 (enExample)
AU (1) AU2001285633A1 (enExample)
CA (1) CA2420477A1 (enExample)
DE (1) DE60127421T8 (enExample)
ES (1) ES2284681T3 (enExample)
WO (1) WO2002016440A2 (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7527797B1 (en) 2000-09-01 2009-05-05 The United States Of America As Represented By The Secretary Of The Department Of Health And Human Services Vibrio cholerae 0139 conjugate vaccines
HUP0700044A2 (en) 2004-05-14 2009-03-30 Ca Nat Research Council Conserved inner core lipopolysaccharide epitopes as multi-species vaccine candidates
US8795680B2 (en) * 2006-07-21 2014-08-05 The United States Of America, As Represented By The Secretary, Department Of Health And Human Services Methods for conjugation of oligosaccharides or polysaccharides to protein carriers through oxime linkages via 3-deoxy-D-manno-octulsonic acid
JP2008125425A (ja) * 2006-11-20 2008-06-05 Osaka Univ 核酸の増幅反応に用いる繰返し配列結合プライマー及びその利用
CA2680038A1 (en) * 2007-03-08 2008-09-12 The Governors Of The University Of Alberta Bacterial endotoxin for the prevention of metabolic disorders and bacterial infections
WO2016007891A1 (en) * 2014-07-10 2016-01-14 University Of Iowa Research Foundation Vaccine for nontypeable haemophilus influenzae

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0347425B1 (en) 1987-03-02 1995-12-27 Whitehead Institute For Biomedical Research Recombinant mycobacterial vaccine
US5504005A (en) 1987-03-02 1996-04-02 Albert Einstein College Of Medicine Of Yeshiva University Recombinant mycobacterial vaccine
US5204098A (en) * 1988-02-16 1993-04-20 The United States Of America As Represented By The Department Of Health And Human Services Polysaccharide-protein conjugates
ZA894589B (en) * 1989-02-09 1991-02-27 K Sudan Krishan Semi-flexible or flexible phenolic foam
CA2076753A1 (en) 1990-02-26 1991-08-27 Anthony J. Radford Shuttle plasmid for escherichia coli and mycobacteria
GB9015888D0 (en) 1990-07-19 1990-09-05 Smithkline Biolog Vectors
US5153312A (en) * 1990-09-28 1992-10-06 American Cyanamid Company Oligosaccharide conjugate vaccines
WO1992011361A1 (en) 1990-12-18 1992-07-09 The General Hospital Corporation Improved vaccines
EP0587775A4 (en) 1991-06-06 1994-11-02 Medimmune Inc INDUCTION OF THE CTL RESPONSE BY FOREIGN ANTIGENS EXPRESSED IN MYCOBACTERIES.
US5283185A (en) * 1991-08-28 1994-02-01 University Of Tennessee Research Corporation Method for delivering nucleic acids into cells
WO1994016737A1 (en) 1993-01-26 1994-08-04 Weiner David B Compositions and methods for delivery of genetic material
GB9326174D0 (en) 1993-12-22 1994-02-23 Biocine Sclavo Mucosal adjuvant
US20030072774A1 (en) 1994-06-10 2003-04-17 Diane M. Gajewczyk Proteinaceous adjuvants
US6019982A (en) 1994-08-26 2000-02-01 The Administrators Of The Tulane Educational Fund Mutant enterotoxin effective as a non-toxic oral adjuvant
US5527928A (en) * 1994-09-30 1996-06-18 Nantz; Michael H. Cationic transport reagents
US6207157B1 (en) * 1996-04-23 2001-03-27 The United States Of America As Represented By The Department Of Health And Human Services Conjugate vaccine for nontypeable Haemophilus influenzae
CA2264970A1 (en) 1998-03-10 1999-09-10 American Cyanamid Company Antigenic conjugates of conserved lipolysaccharides of gram negative bacteria
US6248329B1 (en) * 1998-06-01 2001-06-19 Ramaswamy Chandrashekar Parasitic helminth cuticlin nucleic acid molecules and uses thereof
DE19844191A1 (de) 1998-09-28 2000-03-30 Pharma Zentrale Gmbh Lipopolysaccharide aus Escherichia coli
DE69926261T2 (de) * 1998-12-15 2006-05-24 Exiqon A/S Koppeln an feste phasen von kohlenhydraten, die von lipopolysacchariden abgeleitet sind
CA2374235A1 (en) 1999-05-18 2000-11-23 University Of Iowa Research Foundation Production of complex carbohydrates

Also Published As

Publication number Publication date
AU2001285633A1 (en) 2002-03-04
EP1313771B1 (en) 2007-03-21
EP1313771A2 (en) 2003-05-28
US7364739B2 (en) 2008-04-29
WO2002016440A8 (en) 2002-11-14
ES2284681T3 (es) 2007-11-16
DE60127421T2 (de) 2007-11-29
WO2002016440A9 (en) 2004-05-13
CA2420477A1 (en) 2002-02-28
WO2002016440A3 (en) 2002-06-06
JP2004506086A (ja) 2004-02-26
DE60127421D1 (de) 2007-05-03
WO2002016440A2 (en) 2002-02-28
US20050153057A1 (en) 2005-07-14
ATE357461T1 (de) 2007-04-15

Similar Documents

Publication Publication Date Title
YU8192A (sh) Postupak za izradu pneumokoknog polisaharidnog imunogenog proteinskog konjugata
MXPA03008154A (es) Novedoso adyuvante de vacuna de proteosoma-liposacarido.
NZ513840A (en) Vaccine
FI931169A0 (fi) Foerbaettrade vaccinkompositioner
MA30065B1 (fr) Vaccin
MXPA05009351A (es) Conjugados de polisacarido-proteina portadora adhesina superficial de estafilococo para inmunizacion contra infecciones nosocomiales.
GB0313916D0 (en) Vaccine composition
MX341760B (es) Vacuna del conjugado proteina - polisacarido meningococico, multivalente.
YU24391A (sh) Poboljšana meningokokna polisaharid kon-jugovana vakcina
WO2002091998A3 (en) Novel meningitis conjugate vaccine
NO913812D0 (no) Oligosakkaridkonjugatvaksiner.
PT1104306E (pt) Composicoes de cpg e adjuvantes de saponina e seus metodos
DE60325696D1 (de) Synthese von lipopolysaccharid-protein konjugatvaccinen über die lipid-a region nach entfernung des glycosidischen phosphatresidüs
WO2010141312A3 (en) Flagellin fusion proteins and conjugates comprising pneumococcus antigens and methods of using the same
NL300231I1 (nl) Polyribosylribitolfosfaat omvattende entstofsamenstelling tegen haemophilus influenza type b en werkwijze voor de bereiding ervan.
DE60127421D1 (de) Innen-kern oligosaccharide epitopes aus lipopolysacchariden von haemophilus influenza als vakzinen in der prophylaktischen behandlung von haemophilus influenzae infektionen
ATE364395T1 (de) Konjugat-impfstoffe zur vorbeugung der zahnkaries
WO2001078787A3 (en) Lipopolysaccharide-conjugate vaccine for sepsis treatment
WO2001022994A3 (en) Vaccines against neisseria infection
ATE494908T1 (de) Pflanzen lektine als mukosale adjuvantien

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee