JP2004505649A5 - - Google Patents
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- JP2004505649A5 JP2004505649A5 JP2002519613A JP2002519613A JP2004505649A5 JP 2004505649 A5 JP2004505649 A5 JP 2004505649A5 JP 2002519613 A JP2002519613 A JP 2002519613A JP 2002519613 A JP2002519613 A JP 2002519613A JP 2004505649 A5 JP2004505649 A5 JP 2004505649A5
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- JP
- Japan
- Prior art keywords
- protein
- nucleic acid
- substance
- acid sequence
- acid molecule
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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- 108090000623 proteins and genes Proteins 0.000 description 35
- 102000004169 proteins and genes Human genes 0.000 description 35
- 150000007523 nucleic acids Chemical group 0.000 description 27
- 108020004707 nucleic acids Proteins 0.000 description 17
- 102000039446 nucleic acids Human genes 0.000 description 17
- 238000000034 method Methods 0.000 description 16
- 239000000126 substance Substances 0.000 description 14
- 108091028043 Nucleic acid sequence Proteins 0.000 description 9
- 101000605518 Homo sapiens Kallikrein-15 Proteins 0.000 description 8
- 102100038301 Kallikrein-15 Human genes 0.000 description 8
- 150000001875 compounds Chemical class 0.000 description 7
- 125000003275 alpha amino acid group Chemical group 0.000 description 5
- 239000012472 biological sample Substances 0.000 description 5
- 238000009396 hybridization Methods 0.000 description 4
- 239000000523 sample Substances 0.000 description 4
- 206010028980 Neoplasm Diseases 0.000 description 3
- 201000011510 cancer Diseases 0.000 description 3
- 230000000295 complement effect Effects 0.000 description 3
- 239000003795 chemical substances by application Substances 0.000 description 2
- 230000009918 complex formation Effects 0.000 description 2
- 239000003814 drug Substances 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 238000012544 monitoring process Methods 0.000 description 2
- 230000000144 pharmacologic effect Effects 0.000 description 2
- 239000011541 reaction mixture Substances 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 229960005486 vaccine Drugs 0.000 description 2
- 108020004705 Codon Proteins 0.000 description 1
- 241001465754 Metazoa Species 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 230000004071 biological effect Effects 0.000 description 1
- 238000012258 culturing Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003937 drug carrier Substances 0.000 description 1
- 238000007876 drug discovery Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 239000012634 fragment Substances 0.000 description 1
- 230000002068 genetic effect Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000001404 mediated effect Effects 0.000 description 1
- 239000000203 mixture Substances 0.000 description 1
- 239000002773 nucleotide Substances 0.000 description 1
- 125000003729 nucleotide group Chemical group 0.000 description 1
- 239000008194 pharmaceutical composition Substances 0.000 description 1
- 239000000546 pharmaceutical excipient Substances 0.000 description 1
- 239000000825 pharmaceutical preparation Substances 0.000 description 1
- 238000003752 polymerase chain reaction Methods 0.000 description 1
- 229920001184 polypeptide Polymers 0.000 description 1
- 102000004196 processed proteins & peptides Human genes 0.000 description 1
- 108090000765 processed proteins & peptides Proteins 0.000 description 1
- 230000006916 protein interaction Effects 0.000 description 1
- 230000004936 stimulating effect Effects 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US22485300P | 2000-08-11 | 2000-08-11 | |
| PCT/CA2001/001141 WO2002014485A2 (en) | 2000-08-11 | 2001-08-10 | Kallikrein gene |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004505649A JP2004505649A (ja) | 2004-02-26 |
| JP2004505649A5 true JP2004505649A5 (https=) | 2008-10-02 |
Family
ID=22842508
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002519613A Pending JP2004505649A (ja) | 2000-08-11 | 2001-08-10 | 新規なカリクレイン遺伝子 |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US7199229B2 (https=) |
| EP (1) | EP1309703B1 (https=) |
| JP (1) | JP2004505649A (https=) |
| AT (1) | ATE330017T1 (https=) |
| AU (2) | AU8738401A (https=) |
| CA (1) | CA2418422C (https=) |
| DE (1) | DE60120712T2 (https=) |
| ES (1) | ES2266245T3 (https=) |
| WO (1) | WO2002014485A2 (https=) |
Families Citing this family (23)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022497B1 (en) * | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| US9012141B2 (en) * | 2000-03-27 | 2015-04-21 | Advaxis, Inc. | Compositions and methods comprising KLK3 of FOLH1 antigen |
| WO2002014485A2 (en) | 2000-08-11 | 2002-02-21 | Mount Sinai Hospital | Kallikrein gene |
| ATE365922T1 (de) * | 2000-10-27 | 2007-07-15 | Mount Sinai Hospital Corp | Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) |
| JP2004512540A (ja) | 2000-11-01 | 2004-04-22 | マウント・サイナイ・ホスピタル | 卵巣癌の検出 |
| US20040203012A1 (en) * | 2001-05-25 | 2004-10-14 | Eleftherios Diamandis | Method of detecting and monitoring prostate and ovarian cancers |
| CA2463920A1 (en) * | 2001-10-16 | 2003-04-24 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| AU2003269618A1 (en) * | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| CA2497061A1 (en) * | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| EP1546728A2 (en) * | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2516591A1 (en) * | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004077060A2 (en) * | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| CA2468651A1 (en) * | 2003-06-13 | 2004-12-13 | Eleftherios P. Diamandis | Detection of neurodegenerative diseases |
| US20060269971A1 (en) * | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
| EP1711616A1 (en) * | 2004-01-28 | 2006-10-18 | Bayer HealthCare AG | Diagnostics and therapeutics for diseases associated with kallikrein 15 (klk15) |
| US20110129499A1 (en) | 2008-05-19 | 2011-06-02 | Paulo Maciag | Dual delivery system for heterologous antigens |
| US9017660B2 (en) | 2009-11-11 | 2015-04-28 | Advaxis, Inc. | Compositions and methods for prevention of escape mutation in the treatment of Her2/neu over-expressing tumors |
| US9650639B2 (en) | 2008-05-19 | 2017-05-16 | Advaxis, Inc. | Dual delivery system for heterologous antigens |
| US10016617B2 (en) | 2009-11-11 | 2018-07-10 | The Trustees Of The University Of Pennsylvania | Combination immuno therapy and radiotherapy for the treatment of Her-2-positive cancers |
| US9226958B2 (en) | 2010-10-01 | 2016-01-05 | University Of Georgia Research Foundation, Inc. | Use of Listeria vaccine vectors to reverse vaccine unresponsiveness in parasitically infected individuals |
| AU2012229218B2 (en) | 2011-03-11 | 2017-03-02 | Advaxis, Inc. | Listeria-based adjuvants |
| CN104411327A (zh) | 2012-03-12 | 2015-03-11 | 阿德瓦希斯公司 | 李斯特菌疫苗治疗以后的抑制细胞功能抑制 |
| GB201513921D0 (en) * | 2015-08-05 | 2015-09-23 | Immatics Biotechnologies Gmbh | Novel peptides and combination of peptides for use in immunotherapy against prostate cancer and other cancers |
Family Cites Families (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7022497B1 (en) | 1999-03-11 | 2006-04-04 | Mt. Sinai Hospital | Human kallikrein-like genes |
| US20020064856A1 (en) * | 2000-06-26 | 2002-05-30 | Gregory Plowman | Novel proteases |
| JP2004515220A (ja) * | 2000-07-21 | 2004-05-27 | インサイト・ゲノミックス・インコーポレイテッド | プロテアーゼ |
| WO2002014485A2 (en) | 2000-08-11 | 2002-02-21 | Mount Sinai Hospital | Kallikrein gene |
| CA2360219A1 (en) | 2000-10-27 | 2002-04-27 | Mount Sinai Hospital | Method for detecting alzheimer's disease |
| ATE365922T1 (de) * | 2000-10-27 | 2007-07-15 | Mount Sinai Hospital Corp | Verfahren zur erkennung von eierstockkrebs mittels menschlichem kallikrein (hk6) |
| JP2004512540A (ja) * | 2000-11-01 | 2004-04-22 | マウント・サイナイ・ホスピタル | 卵巣癌の検出 |
| US20040203012A1 (en) * | 2001-05-25 | 2004-10-14 | Eleftherios Diamandis | Method of detecting and monitoring prostate and ovarian cancers |
| CA2463920A1 (en) * | 2001-10-16 | 2003-04-24 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| US20050287528A1 (en) | 2002-04-04 | 2005-12-29 | Mount Sinai Hospital | Methods for detecting ovarian cancer |
| CA2497061A1 (en) | 2002-08-28 | 2004-03-11 | Mount Sinai Hospital | Methods for detecting endocrine cancer using kallikrein 13 (klk13) as a biomarker |
| AU2003269618A1 (en) | 2002-08-28 | 2004-03-19 | Mount Sinai Hospital | Methods for detecting breast and ovarian cancer |
| EP1546728A2 (en) | 2002-09-26 | 2005-06-29 | Mount Sinai Hospital | Methods for detecting endocrine cancer |
| CA2516591A1 (en) | 2003-02-26 | 2004-09-10 | Mount Sinai Hospital | Multiple marker assay for detection of ovarian cancer |
| WO2004077060A2 (en) | 2003-02-27 | 2004-09-10 | Mount Sinai Hospital | Assay for detection of renal cell carcinoma |
| CA2468651A1 (en) | 2003-06-13 | 2004-12-13 | Eleftherios P. Diamandis | Detection of neurodegenerative diseases |
| US20060269971A1 (en) | 2003-09-26 | 2006-11-30 | Mount Sinai Hospital | Methods for detecting prostate cancer |
-
2001
- 2001-08-10 WO PCT/CA2001/001141 patent/WO2002014485A2/en not_active Ceased
- 2001-08-10 ES ES01966837T patent/ES2266245T3/es not_active Expired - Lifetime
- 2001-08-10 AU AU8738401A patent/AU8738401A/xx active Pending
- 2001-08-10 AU AU2001287384A patent/AU2001287384B2/en not_active Ceased
- 2001-08-10 JP JP2002519613A patent/JP2004505649A/ja active Pending
- 2001-08-10 US US10/344,394 patent/US7199229B2/en not_active Expired - Fee Related
- 2001-08-10 DE DE60120712T patent/DE60120712T2/de not_active Expired - Lifetime
- 2001-08-10 CA CA2418422A patent/CA2418422C/en not_active Expired - Fee Related
- 2001-08-10 EP EP01966837A patent/EP1309703B1/en not_active Expired - Lifetime
- 2001-08-10 AT AT01966837T patent/ATE330017T1/de not_active IP Right Cessation
-
2007
- 2007-03-29 US US11/729,560 patent/US7507403B2/en not_active Expired - Fee Related
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