JP2004505004A5 - - Google Patents

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Publication number
JP2004505004A5
JP2004505004A5 JP2000610469A JP2000610469A JP2004505004A5 JP 2004505004 A5 JP2004505004 A5 JP 2004505004A5 JP 2000610469 A JP2000610469 A JP 2000610469A JP 2000610469 A JP2000610469 A JP 2000610469A JP 2004505004 A5 JP2004505004 A5 JP 2004505004A5
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JP
Japan
Prior art keywords
formula
alkyl
compound
hydrogen
oxygen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
JP2000610469A
Other languages
English (en)
Japanese (ja)
Other versions
JP4825353B2 (ja
JP2004505004A (ja
Filing date
Publication date
Application filed filed Critical
Priority claimed from PCT/US2000/008337 external-priority patent/WO2000061136A1/en
Publication of JP2004505004A publication Critical patent/JP2004505004A/ja
Publication of JP2004505004A5 publication Critical patent/JP2004505004A5/ja
Application granted granted Critical
Publication of JP4825353B2 publication Critical patent/JP4825353B2/ja
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

JP2000610469A 1999-04-08 2000-03-30 血圧を下げることに有用な抗痙攣薬誘導体 Expired - Lifetime JP4825353B2 (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US12840099P 1999-04-08 1999-04-08
US60/128,400 1999-04-08
US09/538,182 2000-03-30
PCT/US2000/008337 WO2000061136A1 (en) 1999-04-08 2000-03-30 Anticonvulsant derivatives useful in lowering blood pressure
US09/538,182 US6201010B1 (en) 1999-04-08 2000-03-30 Anticonvulsant derivatives useful in lowering blood pressure

Publications (3)

Publication Number Publication Date
JP2004505004A JP2004505004A (ja) 2004-02-19
JP2004505004A5 true JP2004505004A5 (enExample) 2007-02-15
JP4825353B2 JP4825353B2 (ja) 2011-11-30

Family

ID=26826549

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2000610469A Expired - Lifetime JP4825353B2 (ja) 1999-04-08 2000-03-30 血圧を下げることに有用な抗痙攣薬誘導体

Country Status (7)

Country Link
US (1) US6201010B1 (enExample)
JP (1) JP4825353B2 (enExample)
AU (1) AU775849B2 (enExample)
CA (1) CA2369091C (enExample)
MX (1) MXPA01010221A (enExample)
NZ (1) NZ514812A (enExample)
WO (1) WO2000061136A1 (enExample)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20080103179A1 (en) * 2006-10-27 2008-05-01 Tam Peter Y Combination Therapy
US7659256B2 (en) * 1999-06-14 2010-02-09 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US7056890B2 (en) * 1999-06-14 2006-06-06 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US7674776B2 (en) 1999-06-14 2010-03-09 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US7553818B2 (en) * 1999-06-14 2009-06-30 Vivus, Inc. Combination therapy for effecting weight loss and treating obesity
US20080255093A1 (en) * 1999-06-14 2008-10-16 Tam Peter Y Compositions and methods for treating obesity and related disorders
US7927613B2 (en) 2002-02-15 2011-04-19 University Of South Florida Pharmaceutical co-crystal compositions
US20090088443A1 (en) * 2002-02-15 2009-04-02 Julius Remenar Novel crystalline forms of conazoles and methods of making and using the same
US6559293B1 (en) 2002-02-15 2003-05-06 Transform Pharmaceuticals, Inc. Topiramate sodium trihydrate
US20100311701A1 (en) * 2002-02-15 2010-12-09 Transform Pharmaceuticals, Inc Pharmaceutical Co-Crystal Compositions
US7790905B2 (en) * 2002-02-15 2010-09-07 Mcneil-Ppc, Inc. Pharmaceutical propylene glycol solvate compositions
EP1494998A2 (en) * 2002-03-01 2005-01-12 University Of South Florida Multiple-component solid phases containing at least one active pharmaceutical ingredient
US20070059356A1 (en) * 2002-05-31 2007-03-15 Almarsson Oern Pharmaceutical co-crystal compositions of drugs such as carbamazepine, celecoxib, olanzapine, itraconazole, topiramate, modafinil, 5-fluorouracil, hydrochlorothiazide, acetaminophen, aspirin, flurbiprofen, phenytoin and ibuprofen
MXPA05000232A (es) * 2002-06-21 2005-06-17 Transform Pharmaceuticals Inc Composiciones farmaceuticas con disolucion mejorada.
US8183290B2 (en) 2002-12-30 2012-05-22 Mcneil-Ppc, Inc. Pharmaceutically acceptable propylene glycol solvate of naproxen
US6949518B1 (en) 2003-06-25 2005-09-27 Pao-Hsien Chu Methods for treating macular degeneration with topiramate
WO2008027557A2 (en) * 2006-08-31 2008-03-06 Spherics, Inc. Topiramate compositions and methods of enhancing its bioavailability
EP1973528B1 (en) 2006-11-17 2012-11-07 Supernus Pharmaceuticals, Inc. Sustained-release formulations of topiramate
WO2008070670A2 (en) * 2006-12-04 2008-06-12 Supernus Pharmaceuticals, Inc. Enhanced immediate release formulations of topiramate
US8580298B2 (en) 2008-06-09 2013-11-12 Vivus, Inc. Low dose topiramate/phentermine composition and methods of use thereof
US20090304789A1 (en) 2008-06-09 2009-12-10 Thomas Najarian Novel topiramate compositions and an escalating dosing strategy for treating obesity and related disorders
US9457008B2 (en) 2012-03-23 2016-10-04 Institute Of Pharmacology And Toxicology Academy Of Military Medical Sciences P.L.A. China Joint product comprising synephrine and topiramate
CN102579367B (zh) 2012-03-23 2014-03-12 中国人民解放军军事医学科学院毒物药物研究所 托吡酯缓释药物组合物、其制备方法及用途
CN103316026B (zh) 2012-03-23 2016-05-11 中国人民解放军军事医学科学院毒物药物研究所 含芬特明和托吡酯的联合产品及其制备方法
US8652527B1 (en) 2013-03-13 2014-02-18 Upsher-Smith Laboratories, Inc Extended-release topiramate capsules
US9101545B2 (en) 2013-03-15 2015-08-11 Upsher-Smith Laboratories, Inc. Extended-release topiramate capsules
WO2020104837A1 (en) 2018-11-21 2020-05-28 Rosemont Pharmaceuticals Limited Oral topiramate suspension formulations with extended shelf stability and enhanced bioavailability

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4513006A (en) * 1983-09-26 1985-04-23 Mcneil Lab., Inc. Anticonvulsant sulfamate derivatives
US5242942A (en) * 1992-04-28 1993-09-07 Mcneilab, Inc. Anticonvulsant fructopyranose cyclic sulfites and sulfates
US5258402A (en) * 1992-06-11 1993-11-02 Mcneil-Ppc, Inc. Imidate derivatives of pharmaceutically useful anticonvulsant sulfamates
US5998380A (en) * 1995-10-13 1999-12-07 New England Medical Center Hospitals, Inc. Treatment of migraine
SK284305B6 (sk) * 1996-06-28 2005-01-03 Ortho-Mcneil Pharmaceutical, Inc. Liečivo na liečbu obezity

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