JP2004504032A - 性的機能不全の処置用の新規なヒト可溶性分泌エンドペプチダーゼ（ｓｅｐ） - Google Patents

性的機能不全の処置用の新規なヒト可溶性分泌エンドペプチダーゼ（ｓｅｐ） Download PDF

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JP2004504032A
JP2004504032A JP2002512384A JP2002512384A JP2004504032A JP 2004504032 A JP2004504032 A JP 2004504032A JP 2002512384 A JP2002512384 A JP 2002512384A JP 2002512384 A JP2002512384 A JP 2002512384A JP 2004504032 A JP2004504032 A JP 2004504032A
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polypeptide
sep
human sep
sequence
human
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JP2004504032A5 (enExample
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ハロー，イアン・デニス
ステイシー，ピーター
ウォルシュ，ロデリック・トーマス
ウェイマン，クリストファー・ピーター
フィリップス，スティーヴン・チャールズ
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ファイザー・インク
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    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/165—Amides, e.g. hydroxamic acids having aromatic rings, e.g. colchicine, atenolol, progabide
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    • A61K31/16—Amides, e.g. hydroxamic acids
    • A61K31/17—Amides, e.g. hydroxamic acids having the group >N—C(O)—N< or >N—C(S)—N<, e.g. urea, thiourea, carmustine
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    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19—Carboxylic acids, e.g. valproic acid
    • A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/196—Carboxylic acids, e.g. valproic acid having an amino group the amino group being directly attached to a ring, e.g. anthranilic acid, mefenamic acid, diclofenac, chlorambucil
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    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/4015—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil having oxo groups directly attached to the heterocyclic ring, e.g. piracetam, ethosuximide
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    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • G01N2800/344—Disorders of the penis and the scrotum and erectile dysfuncrion

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JP2002512384A 2000-07-14 2001-07-16 性的機能不全の処置用の新規なヒト可溶性分泌エンドペプチダーゼ（ｓｅｐ） Pending JP2004504032A (ja)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB0017387.2A GB0017387D0 (en) 2000-07-14 2000-07-14 Novel enzyme
PCT/IB2001/001263 WO2002006492A1 (en) 2000-07-14 2001-07-16 A novel human soluble secreted endopeptidase (sep) for the treatment of sexual dysunfction

Publications (2)

Publication Number Publication Date
JP2004504032A true JP2004504032A (ja) 2004-02-12
JP2004504032A5 JP2004504032A5 (enExample) 2005-02-24

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ID=9895717

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JP2002512384A Pending JP2004504032A (ja) 2000-07-14 2001-07-16 性的機能不全の処置用の新規なヒト可溶性分泌エンドペプチダーゼ（ｓｅｐ）

Country Status (8)

Country Link
US (1) US6878529B2 (enExample)
EP (1) EP1303619A1 (enExample)
JP (1) JP2004504032A (enExample)
AU (1) AU2001269371A1 (enExample)
CA (1) CA2415557A1 (enExample)
GB (1) GB0017387D0 (enExample)
MX (1) MXPA03000426A (enExample)
WO (1) WO2002006492A1 (enExample)

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GB0017387D0 (en) * 2000-07-14 2000-08-30 Pfizer Ltd Novel enzyme
US6991916B2 (en) * 2000-07-14 2006-01-31 Pfizer Inc. Compounds for the treatment of sexual dysfunction
US20020091129A1 (en) * 2000-11-20 2002-07-11 Mitradev Boolell Treatment of premature ejaculation
US6885895B1 (en) * 2001-04-26 2005-04-26 Advanced Bionics Corporation Methods and systems for electrical and/or drug stimulation as a therapy for erectile dysfunction
MXPA03010341A (es) * 2001-05-18 2004-03-10 Solvay Pharm Gmbh Uso de compuestos con actividad inhibitoria de epn/mp combinada en la preparacion de medicamentos.
US7427611B2 (en) 2003-09-26 2008-09-23 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 1-(carboxyalkyl)-cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
US7262184B2 (en) 2003-09-26 2007-08-28 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
US7452875B2 (en) 2003-09-26 2008-11-18 Solvay Pharmaceuticals Gmbh Amidomethyl-substituted 1-(carboxyalkyl) cyclopentyl-carbonylamino-benzazepine-N-acetic acid compounds, process and intermediate products for their preparation and pharmaceutical compositions containing them
US20050267072A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions containing dually acting inhibitors of neutral endopeptidase for the treatment of sexual dysfunction
WO2005112940A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising nep-inhibitors, inhibitors of the endogenous endothelin producing system and pde v inhibitors
US20050267124A1 (en) * 2004-05-14 2005-12-01 Solvay Pharmaceuticals Gmbh Pharmaceutical compositions comprising NEP-inhibitors, inhibitors of the endogenous producing system and PDEV inhibiitors
WO2005112460A2 (en) * 2004-05-17 2005-11-24 Given Imaging Ltd. Method, system and device for in-vivo biopsy
MX2009010000A (es) 2007-03-19 2010-03-17 Insuline Medical Ltd Dispositivo para el suministro de farmaco.
US8622991B2 (en) 2007-03-19 2014-01-07 Insuline Medical Ltd. Method and device for drug delivery
US9220837B2 (en) 2007-03-19 2015-12-29 Insuline Medical Ltd. Method and device for drug delivery
US8409133B2 (en) 2007-12-18 2013-04-02 Insuline Medical Ltd. Drug delivery device with sensor for closed-loop operation
CA2743027C (en) 2008-11-07 2016-04-12 Insuline Medical Ltd. Device and method for drug delivery
ES2627655T3 (es) 2009-05-19 2017-07-31 Neuroderm Ltd Composiciones para la administración continua de inhibidores de DOPA descarboxilasa
JP5902705B2 (ja) 2010-11-15 2016-04-13 ニューロダーム リミテッドＮｅｕｒｏｄｅｒｍ Ｌｔｄ Ｌ−ドーパ、ドーパデカルボキシラーゼ阻害剤、カテコール−ｏ−メチルトランスフェラーゼ阻害剤、およびそれらのための組成物の継続的投与
WO2013025261A2 (en) * 2011-04-06 2013-02-21 Georgia Tech Research Corporation Fluorogenic peptide probes and assays
US9375202B2 (en) 2012-05-04 2016-06-28 Given Imaging Ltd. Device and method for in vivo cytology acquisition
WO2013183055A1 (en) 2012-06-05 2013-12-12 Neuroderm Ltd Compositions comprising apomorphine and organic acids and uses thereof
US10258585B2 (en) 2014-03-13 2019-04-16 Neuroderm, Ltd. DOPA decarboxylase inhibitor compositions
PT3116475T (pt) 2014-03-13 2020-12-15 Neuroderm Ltd Composições de inibidores de dopa-descarboxilase
CN112546453B (zh) * 2020-10-15 2022-11-29 西安蓝极医疗电子科技有限公司 基于激光照射治疗男性勃起功能障碍的发光体组件及装置
US11844754B2 (en) 2020-11-17 2023-12-19 Neuroderm, Ltd. Methods for treatment of Parkinson's disease
US11331293B1 (en) 2020-11-17 2022-05-17 Neuroderm, Ltd. Method for treatment of Parkinson's disease
US11213502B1 (en) 2020-11-17 2022-01-04 Neuroderm, Ltd. Method for treatment of parkinson's disease
US12161612B2 (en) 2023-04-14 2024-12-10 Neuroderm, Ltd. Methods and compositions for reducing symptoms of Parkinson's disease

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GB0017387D0 (en) * 2000-07-14 2000-08-30 Pfizer Ltd Novel enzyme

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US20020102707A1 (en) 2002-08-01
US6878529B2 (en) 2005-04-12
MXPA03000426A (es) 2003-06-24
CA2415557A1 (en) 2002-01-24
GB0017387D0 (en) 2000-08-30
EP1303619A1 (en) 2003-04-23
WO2002006492A1 (en) 2002-01-24
AU2001269371A1 (en) 2002-01-30

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