JP2004502640A5 - - Google Patents
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- Publication number
- JP2004502640A5 JP2004502640A5 JP2001557366A JP2001557366A JP2004502640A5 JP 2004502640 A5 JP2004502640 A5 JP 2004502640A5 JP 2001557366 A JP2001557366 A JP 2001557366A JP 2001557366 A JP2001557366 A JP 2001557366A JP 2004502640 A5 JP2004502640 A5 JP 2004502640A5
- Authority
- JP
- Japan
- Prior art keywords
- adenosine
- fibrosis
- administering
- subject
- need
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US18154600P | 2000-02-10 | 2000-02-10 | |
| PCT/US2001/004341 WO2001058241A2 (en) | 2000-02-10 | 2001-02-12 | Adenosine a2a receptor antagonists for treating and preventing hepatic fibrosis, cirrhosis and fatty liver |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004502640A JP2004502640A (ja) | 2004-01-29 |
| JP2004502640A5 true JP2004502640A5 (https=) | 2005-02-03 |
Family
ID=22664744
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001557366A Pending JP2004502640A (ja) | 2000-02-10 | 2001-02-12 | 肝繊維症、硬変症および脂肪肝を治療および予防するアデノシンａ２ａ受容体拮抗薬 |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US6555545B2 (https=) |
| EP (1) | EP1272897B1 (https=) |
| JP (1) | JP2004502640A (https=) |
| AT (1) | ATE394104T1 (https=) |
| AU (2) | AU3812401A (https=) |
| CA (1) | CA2398908C (https=) |
| DE (1) | DE60133887D1 (https=) |
| DK (1) | DK1272897T3 (https=) |
| ES (1) | ES2307593T3 (https=) |
| PT (1) | PT1272897E (https=) |
| WO (1) | WO2001058241A2 (https=) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6196459B1 (en) * | 1998-05-11 | 2001-03-06 | Ubiq Incorporated | Smart card personalization in a multistation environment |
| WO2003080649A2 (en) * | 2002-03-20 | 2003-10-02 | Regents Of The University Of Minnesota | Induction of hepatocyte proliferation in vitro by inhibition of cell cycle inhibitors |
| ITRM20070088A1 (it) * | 2007-02-19 | 2008-08-20 | Francesco Fringuelli | Composti derivati della colchicina, procedimento per la loro preparazione e usi in campo medico. |
| CA2695989A1 (en) * | 2007-08-10 | 2009-02-19 | Glaxosmithkline Llc | Certain nitrogen containing bicyclic chemical entities for treating viral infections |
| EP2217233B1 (en) * | 2007-10-26 | 2018-08-08 | New York University School of Medicine | Methods and compositions for treating hepatic diseases |
| ES2541141T3 (es) * | 2008-01-31 | 2015-07-16 | Astellas Pharma Inc. | Composición farmacéutica para el tratamiento de las enfermedades del hígado graso |
| US8536306B2 (en) | 2008-10-01 | 2013-09-17 | The Scripps Research Institute | Human A2A adenosine receptor crystals and uses thereof |
| US20100204265A1 (en) * | 2009-02-09 | 2010-08-12 | Genelabs Technologies, Inc. | Certain Nitrogen Containing Bicyclic Chemical Entities for Treating Viral Infections |
| AU2010222289B2 (en) | 2009-03-13 | 2013-07-11 | Advinus Therapeutics Private Limited | Substituted fused pyrimidine compounds |
| EP2408775B1 (en) * | 2009-03-20 | 2015-06-17 | SIGMA-TAU Industrie Farmaceutiche Riunite S.p.A. | Oxidated derivatives of triazolylpurines useful as ligands of the adenosine a2a receptor and their use as medicaments |
| EP2499142B1 (en) | 2009-11-09 | 2016-09-21 | Advinus Therapeutics Limited | Substituted fused pyrimidine compounds, its preparation and uses thereof |
| ES2579949T3 (es) | 2010-02-05 | 2016-08-17 | Heptares Therapeutics Limited | Derivados de 1,2,4-triazin-4-amina |
| WO2012066330A1 (en) | 2010-11-17 | 2012-05-24 | Heptares Therapeutics Limited | Compounds useful as a2a receptor inhibitors |
| WO2019002606A1 (en) | 2017-06-30 | 2019-01-03 | Selvita S.A. | ADENOSINE A2A RECEPTOR 5,6-BICYCLO-IMIDAZO [1,2-A] PYRAZINE MODULATORS |
| JP7391022B2 (ja) | 2017-12-19 | 2023-12-04 | インペティス・バイオサイエンシーズ・リミテッド | がんの処置のための医薬組成物 |
| IL275817B2 (en) | 2018-01-04 | 2024-04-01 | Impetis Biosciences Ltd | Tricyclic compounds, compositions and medicinal applications thereof |
| WO2020128036A1 (en) | 2018-12-21 | 2020-06-25 | Ryvu Therapeutics S.A. | Modulators of the adenosine a2a receptor |
| WO2025018901A1 (en) | 2023-07-17 | 2025-01-23 | Ryvu Therapeutics S.A. | Modulators of the adenosine a2a and a2b receptor |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4705658A (en) | 1986-04-07 | 1987-11-10 | Capsule Technology International, Ltd. | Method for drying gelatin in the manufacture of hard shell gelatin capsules |
| US5063233A (en) | 1986-11-14 | 1991-11-05 | Ciba-Geigy Corporation | N9 -cyclopentyl-substituted adenine derivatives useful as adenosine receptor agonists |
| US4968697A (en) | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
| US5036381A (en) | 1990-06-15 | 1991-07-30 | Motorola, Inc. | Multiple electronic devices within a single carrier structure |
| GB2264948B (en) | 1992-03-13 | 1996-10-16 | Merck & Co Inc | Human adenosine receptors |
| US5426101A (en) | 1992-09-30 | 1995-06-20 | Merrell Dow Pharmaceuticals Inc. | 2-substituted adenosines with A-2 receptor affinity |
| WO1994023723A1 (en) | 1993-04-15 | 1994-10-27 | New York University | Adenosine receptor agonists for the promotion of wound healing |
| US5877180A (en) * | 1994-07-11 | 1999-03-02 | University Of Virginia Patent Foundation | Method for treating inflammatory diseases with A2a adenosine receptor agonists |
| US5859019A (en) | 1997-03-07 | 1999-01-12 | Trustees Of The University Of Pennsylvania | Methods for protecting against cardiac ischemia by administering adenosine A2a receptor antagonists |
| US6211165B1 (en) * | 1997-05-09 | 2001-04-03 | The Trustees Of The University Of Pennsylvania | Methods and compositions for reducing ischemic injury of the heart by administering adenosine receptor agonists and antagonists |
| AU7449598A (en) * | 1997-05-23 | 1998-12-11 | Nippon Shinyaku Co. Ltd. | Medicinal composition for prevention or treatment of hepatopathy |
| US5916910A (en) | 1997-06-04 | 1999-06-29 | Medinox, Inc. | Conjugates of dithiocarbamates with pharmacologically active agents and uses therefore |
| US6303619B1 (en) * | 1998-03-12 | 2001-10-16 | University Of Virginia | Meta-substituted acidic 8-phenylxanthine antagonists of A3 human adenosine receptors |
| US6232297B1 (en) * | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
-
2001
- 2001-02-12 US US09/780,365 patent/US6555545B2/en not_active Expired - Lifetime
- 2001-02-12 AU AU3812401A patent/AU3812401A/xx active Pending
- 2001-02-12 AT AT01910529T patent/ATE394104T1/de not_active IP Right Cessation
- 2001-02-12 DE DE60133887T patent/DE60133887D1/de not_active Expired - Lifetime
- 2001-02-12 DK DK01910529T patent/DK1272897T3/da active
- 2001-02-12 CA CA002398908A patent/CA2398908C/en not_active Expired - Fee Related
- 2001-02-12 PT PT01910529T patent/PT1272897E/pt unknown
- 2001-02-12 EP EP01910529A patent/EP1272897B1/en not_active Expired - Lifetime
- 2001-02-12 JP JP2001557366A patent/JP2004502640A/ja active Pending
- 2001-02-12 ES ES01910529T patent/ES2307593T3/es not_active Expired - Lifetime
- 2001-02-12 WO PCT/US2001/004341 patent/WO2001058241A2/en not_active Ceased
- 2001-02-12 AU AU2001238124A patent/AU2001238124B2/en not_active Ceased
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