JP2004501650A - 複製欠損アデノウイルスｔｎｆベクター - Google Patents
複製欠損アデノウイルスｔｎｆベクター Download PDFInfo
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- C12N15/09—Recombinant DNA-technology
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- A61K38/17—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- A61K38/19—Cytokines; Lymphokines; Interferons
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
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| PCT/US2001/020536 WO2002000906A2 (en) | 2000-06-27 | 2001-06-27 | Replication deficient adenoviral tnf vector |
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| JP2009509544A (ja) * | 2005-10-01 | 2009-03-12 | チャールズ スタウト， | 調節可能な融合プロモーター |
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| DK1180159T3 (da) * | 1999-05-28 | 2008-11-17 | Targeted Genetics Corp | Fremgangsmåder og sammensætninger til at sænke niveauet af Tumor-Nekrose-Faktor (TNF) i TNF-associerede lidelser |
| US6579522B1 (en) * | 2000-06-27 | 2003-06-17 | Genvec, Inc. | Replication deficient adenoviral TNF vector |
| US20030086903A1 (en) | 2001-11-02 | 2003-05-08 | Genvec, Inc. | Therapeutic regimen for treating cancer |
| US6845929B2 (en) * | 2002-03-22 | 2005-01-25 | Ali Dolatabadi | High efficiency nozzle for thermal spray of high quality, low oxide content coatings |
| US20030223962A1 (en) * | 2002-06-03 | 2003-12-04 | Cornell Research Foundation, Inc. | Delivery of gene products to the lung parenchyma via gene transfer to the pleura |
| DE602004025726D1 (de) * | 2003-11-14 | 2010-04-08 | Genvec Inc | Pharmazeutische verbindung zur behandlung von lokal fortgeschrittenem primär inoperablen pankreaskarzinom (lapc). |
| CN101507822B (zh) * | 2003-11-24 | 2012-06-06 | 坎吉有限公司 | 皮肤瘢痕形成的减少 |
| EP1784493A2 (en) * | 2004-09-01 | 2007-05-16 | The Government of the United States of America as Represented by The Department of Health and Human Services | Adenoviral vectors able to transduce apcs, potential use in immune response generation |
| DE602008004476D1 (de) * | 2007-03-09 | 2011-02-24 | Vectorlogics Inc | Zellen für adenovirusvektor- und proteinherstellung |
| US9605844B2 (en) * | 2009-09-01 | 2017-03-28 | Cree, Inc. | Lighting device with heat dissipation elements |
| WO2011054811A1 (en) | 2009-11-03 | 2011-05-12 | Santaris Pharma A/S | Rna antagonists targeting hsp27 combination therapy |
| WO2012006145A2 (en) * | 2010-06-29 | 2012-01-12 | The Johns Hopkins University | Com positions and methods for retargeting virus constructs |
| KR101429696B1 (ko) | 2012-11-21 | 2014-08-13 | 국립암센터 | 안전성 및 항암활성이 증가된 재조합 아데노바이러스 및 이의 용도 |
| SG11201507393TA (en) | 2013-03-14 | 2015-10-29 | Salk Inst For Biological Studi | Oncolytic adenovirus compositions |
| KR102608590B1 (ko) | 2014-09-24 | 2023-12-01 | 솔크 인스티튜트 포 바이올로지칼 스터디즈 | 종양 살상 바이러스 및 이의 사용방법 |
| WO2017147265A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | High throughput assay for measuring adenovirus replication kinetics |
| WO2017147269A1 (en) | 2016-02-23 | 2017-08-31 | Salk Institute For Biological Studies | Exogenous gene expression in therapeutic adenovirus for minimal impact on viral kinetics |
| EP3532082A4 (en) | 2016-12-12 | 2020-08-26 | Salk Institute for Biological Studies | SYNTHETIC ADENOVIRUS TUMOR TARGETING AND THEIR USES |
| CN112292449A (zh) | 2018-04-09 | 2021-01-29 | 萨克生物研究学院 | 具有增强的复制特性的溶瘤腺病毒组合物 |
| WO2024233783A1 (en) | 2023-05-09 | 2024-11-14 | Cornell University | Expression cassette coding for vascular endothelial growth factor |
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| JPH11501219A (ja) * | 1995-11-28 | 1999-02-02 | ジェンベク、インコーポレイティッド | 細胞への遣伝子導入のためのベクターおよび方法 |
| JPH11502421A (ja) * | 1995-12-14 | 1999-03-02 | ジェンベク、インコーポレイティッド | 相補的なアデノウイルスベクター系と細胞株 |
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-
2000
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- 2001-06-27 EP EP01950575A patent/EP1294918B1/en not_active Expired - Lifetime
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- 2001-06-27 AU AU2001271549A patent/AU2001271549B2/en not_active Ceased
- 2001-06-27 JP JP2002506221A patent/JP2004501650A/ja active Pending
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2003
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2012
- 2012-02-03 JP JP2012022529A patent/JP2012139220A/ja active Pending
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| JPH11513390A (ja) * | 1995-10-06 | 1999-11-16 | アーチ デベロップメント コーポレイション | 細胞殺傷のウイルス増強のための方法および組成物 |
| JPH11501219A (ja) * | 1995-11-28 | 1999-02-02 | ジェンベク、インコーポレイティッド | 細胞への遣伝子導入のためのベクターおよび方法 |
| JPH11502421A (ja) * | 1995-12-14 | 1999-03-02 | ジェンベク、インコーポレイティッド | 相補的なアデノウイルスベクター系と細胞株 |
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| JP2009509544A (ja) * | 2005-10-01 | 2009-03-12 | チャールズ スタウト， | 調節可能な融合プロモーター |
| JP2016000047A (ja) * | 2005-10-01 | 2016-01-07 | スタウト， チャールズ | 調節可能な融合プロモーター |
Also Published As
| Publication number | Publication date |
|---|---|
| WO2002000906A2 (en) | 2002-01-03 |
| DE60114006D1 (de) | 2006-02-23 |
| US20030175245A1 (en) | 2003-09-18 |
| ATE306555T1 (de) | 2005-10-15 |
| US6579522B1 (en) | 2003-06-17 |
| AU7154901A (en) | 2002-01-08 |
| WO2002000906A3 (en) | 2002-06-06 |
| EP1294918B1 (en) | 2005-10-12 |
| JP2012139220A (ja) | 2012-07-26 |
| CA2412637A1 (en) | 2002-01-03 |
| EP1294918A2 (en) | 2003-03-26 |
| DE60114006T2 (de) | 2006-07-20 |
| AU2001271549B2 (en) | 2005-06-09 |
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