JP2004279424A - 質量分析法を用いた生体高分子の同定方法及び及びそれに使用されるプログラム製品 - Google Patents

質量分析法を用いた生体高分子の同定方法及び及びそれに使用されるプログラム製品 Download PDF

Info

Publication number
JP2004279424A
JP2004279424A JP2004069966A JP2004069966A JP2004279424A JP 2004279424 A JP2004279424 A JP 2004279424A JP 2004069966 A JP2004069966 A JP 2004069966A JP 2004069966 A JP2004069966 A JP 2004069966A JP 2004279424 A JP2004279424 A JP 2004279424A
Authority
JP
Japan
Prior art keywords
mass
data set
sequence
biopolymer
delta
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2004069966A
Other languages
English (en)
Japanese (ja)
Other versions
JP2004279424A5 (enExample
Inventor
Dean R Thompson
ディーン・アール・トンプソン
Steven M Fischer
スティーブン・エム・フィッチャー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agilent Technologies Inc
Original Assignee
Agilent Technologies Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agilent Technologies Inc filed Critical Agilent Technologies Inc
Publication of JP2004279424A publication Critical patent/JP2004279424A/ja
Publication of JP2004279424A5 publication Critical patent/JP2004279424A5/ja
Pending legal-status Critical Current

Links

Images

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6848Methods of protein analysis involving mass spectrometry
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N30/00Investigating or analysing materials by separation into components using adsorption, absorption or similar phenomena or using ion-exchange, e.g. chromatography or field flow fractionation
    • G01N30/02Column chromatography
    • G01N30/62Detectors specially adapted therefor
    • G01N30/72Mass spectrometers
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J49/00Particle spectrometers or separator tubes
    • H01J49/004Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn
    • H01J49/0045Combinations of spectrometers, tandem spectrometers, e.g. MS/MS, MSn characterised by the fragmentation or other specific reaction
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/24Nuclear magnetic resonance, electron spin resonance or other spin effects or mass spectrometry

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Physics & Mathematics (AREA)
  • Molecular Biology (AREA)
  • Immunology (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biomedical Technology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Hematology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Urology & Nephrology (AREA)
  • Biophysics (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Spectroscopy & Molecular Physics (AREA)
  • Microbiology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
JP2004069966A 2003-03-13 2004-03-12 質量分析法を用いた生体高分子の同定方法及び及びそれに使用されるプログラム製品 Pending JP2004279424A (ja)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US10/388,088 US8507285B2 (en) 2003-03-13 2003-03-13 Methods and devices for identifying biopolymers using mass spectroscopy

Publications (2)

Publication Number Publication Date
JP2004279424A true JP2004279424A (ja) 2004-10-07
JP2004279424A5 JP2004279424A5 (enExample) 2007-04-19

Family

ID=32771627

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2004069966A Pending JP2004279424A (ja) 2003-03-13 2004-03-12 質量分析法を用いた生体高分子の同定方法及び及びそれに使用されるプログラム製品

Country Status (4)

Country Link
US (1) US8507285B2 (enExample)
EP (1) EP1457776B1 (enExample)
JP (1) JP2004279424A (enExample)
DE (1) DE602004012637T2 (enExample)

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006284305A (ja) * 2005-03-31 2006-10-19 Nec Corp 分析方法および分析システム
JP2007132919A (ja) * 2005-05-03 2007-05-31 Palo Alto Research Center Inc イオン化分子フラグメントを分類するための方法、装置、及びプログラム製品
JP2017142173A (ja) * 2016-02-10 2017-08-17 日本電子株式会社 マススペクトル解析装置、マススペクトル解析方法、質量分析装置、およびプログラム
JP2017535773A (ja) * 2014-11-13 2017-11-30 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 修飾化合物の識別の決定

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020115056A1 (en) * 2000-12-26 2002-08-22 Goodlett David R. Rapid and quantitative proteome analysis and related methods
GB0305796D0 (en) 2002-07-24 2003-04-16 Micromass Ltd Method of mass spectrometry and a mass spectrometer
GB2432712B (en) * 2005-11-23 2007-12-27 Micromass Ltd Mass spectrometer
JP4811466B2 (ja) * 2006-11-15 2011-11-09 株式会社島津製作所 質量分析方法及び質量分析装置
US8153961B2 (en) * 2009-08-31 2012-04-10 Thermo Finnigan Llc Methods for acquisition and deductive analysis of mixed fragment peptide mass spectra
US8935101B2 (en) * 2010-12-16 2015-01-13 Thermo Finnigan Llc Method and apparatus for correlating precursor and product ions in all-ions fragmentation experiments
CN104798174B (zh) * 2012-12-20 2017-09-08 Dh科技发展私人贸易有限公司 用于使用多个光谱以不同碰撞能量进行化合物识别的系统、方法及设备
US10446376B2 (en) 2012-12-20 2019-10-15 Dh Technologies Development Pte. Ltd. Compound identification using multiple spectra at different collision energies
WO2019232520A1 (en) * 2018-06-01 2019-12-05 Cerno Bioscience Llc Mass spectral analysis of large molecules
CN108776144B (zh) * 2018-06-12 2020-10-09 南京大学 一种基于基团光谱特征的海洋溢油乳化物遥感识别方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1130399B1 (en) * 1992-05-29 2009-04-01 The Rockefeller University Method for the sequence determination of peptides using a mass spectrometer
US5470753A (en) * 1992-09-03 1995-11-28 Selectide Corporation Peptide sequencing using mass spectrometry
DE69433811T2 (de) * 1993-01-07 2005-06-23 Sequenom, Inc., San Diego Dns - sequenzierung durch massenspektronomie
US6017693A (en) * 1994-03-14 2000-01-25 University Of Washington Identification of nucleotides, amino acids, or carbohydrates by mass spectrometry
US6051378A (en) * 1996-03-04 2000-04-18 Genetrace Systems Inc. Methods of screening nucleic acids using mass spectrometry
US5885775A (en) * 1996-10-04 1999-03-23 Perseptive Biosystems, Inc. Methods for determining sequences information in polynucleotides using mass spectrometry
DE19709086B4 (de) * 1997-03-06 2007-03-15 Bruker Daltonik Gmbh Verfahren der Raumladungsregelung von Tochterionen in Ionenfallen
US6104027A (en) * 1998-06-05 2000-08-15 Hewlett-Packard Company Deconvolution of multiply charged ions
KR20030074773A (ko) 2001-02-01 2003-09-19 싸이퍼젠 바이오시스템즈, 인코포레이티드 탠덤 질량 분광계에 의한 단백질 확인, 특성화 및 서열결정을 위한 개선된 방법
EP3467122A1 (en) 2001-06-21 2019-04-10 Cell Signaling Technology, Inc. Immunoaffinity isolation of modified peptides from complex mixtures
WO2003006951A2 (en) * 2001-07-13 2003-01-23 Syngenta Participations Ag System and method of determining proteomic differences
US7351957B2 (en) * 2002-04-29 2008-04-01 Mds Inc. Broad ion fragmentation coverage in mass spectrometry by varying the collision energy

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2006284305A (ja) * 2005-03-31 2006-10-19 Nec Corp 分析方法および分析システム
JP2007132919A (ja) * 2005-05-03 2007-05-31 Palo Alto Research Center Inc イオン化分子フラグメントを分類するための方法、装置、及びプログラム製品
JP2017535773A (ja) * 2014-11-13 2017-11-30 ディーエイチ テクノロジーズ デベロップメント プライベート リミテッド 修飾化合物の識別の決定
JP2017142173A (ja) * 2016-02-10 2017-08-17 日本電子株式会社 マススペクトル解析装置、マススペクトル解析方法、質量分析装置、およびプログラム

Also Published As

Publication number Publication date
EP1457776A2 (en) 2004-09-15
US8507285B2 (en) 2013-08-13
EP1457776A3 (en) 2004-09-29
EP1457776B1 (en) 2008-03-26
DE602004012637D1 (de) 2008-05-08
US20040180446A1 (en) 2004-09-16
DE602004012637T2 (de) 2009-04-16

Similar Documents

Publication Publication Date Title
JP4818270B2 (ja) 選択されたイオンクロマトグラムを使用して先駆物質および断片イオンをグループ化するシステムおよび方法
US7538321B2 (en) Method of identifying substances using mass spectrometry
US9146213B2 (en) Method and apparatus for performing retention time matching
US8592752B2 (en) Techniques for performing retention-time matching of precursor and product ions and for constructing precursor and product ion spectra
US8440465B2 (en) Methods and apparatus for fractionation-based chemical analyses
US9837255B2 (en) Methods for mass spectrometry of mixtures of protein or polypeptides using proton transfer reaction
US8426155B2 (en) Proteome analysis in mass spectrometers containing RF ion traps
US8278115B2 (en) Methods for processing tandem mass spectral data for protein sequence analysis
EP2741224A1 (en) Methods for generating local mass spectral libraries for interpreting multiplexed mass spectra
EP2035829A2 (en) Mass spectrometry biomarker assay
US7626162B2 (en) Mass spectrometry system and mass spectrometry method
EP3775928B1 (en) Analysis method for glycoproteins
EP1457776B1 (en) Methods and devices for identifying biopolymers using mass spectroscopy
EP3971943B1 (en) Using real time search results to dynamically exclude product ions that may be present in the master scan
JP7226265B2 (ja) 糖ペプチド解析装置
JP6065652B2 (ja) 糖鎖構造解析方法及び装置
JPWO2004113905A1 (ja) 質量分析方法および質量分析装置
JP2005510732A (ja) 質量分析法によって自動的にタンパク質の配列決定を行うシステムおよび方法
JP4821400B2 (ja) 構造解析システム
WO2019175568A1 (en) Methods and systems for analysis
JP5983371B2 (ja) ペプチド構造解析方法及び装置
Marvin et al. Identification of proteins from one‐dimensional sodium dodecyl sulfate‐polyacrylamide gel electrophoresis using electrospray quadrupole‐time‐of‐flight tandem mass spectrometry
JP7156207B2 (ja) 糖ペプチド解析装置
JP2008170346A (ja) 質量分析システム
Rawat E-Content

Legal Events

Date Code Title Description
A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20070306

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070306

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20090526

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20090603

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20091104