JP2004248507A5 - - Google Patents
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- Publication number
- JP2004248507A5 JP2004248507A5 JP2002292682A JP2002292682A JP2004248507A5 JP 2004248507 A5 JP2004248507 A5 JP 2004248507A5 JP 2002292682 A JP2002292682 A JP 2002292682A JP 2002292682 A JP2002292682 A JP 2002292682A JP 2004248507 A5 JP2004248507 A5 JP 2004248507A5
- Authority
- JP
- Japan
- Prior art keywords
- neural progenitor
- cells
- neural
- stem cells
- undifferentiated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 210000005155 neural progenitor cell Anatomy 0.000 description 19
- 238000012258 culturing Methods 0.000 description 7
- 238000000034 method Methods 0.000 description 7
- 210000004027 cell Anatomy 0.000 description 6
- 238000002360 preparation method Methods 0.000 description 6
- 230000004069 differentiation Effects 0.000 description 5
- 210000001671 embryonic stem cell Anatomy 0.000 description 5
- 210000000130 stem cell Anatomy 0.000 description 5
- 210000002257 embryonic structure Anatomy 0.000 description 3
- 210000002950 fibroblast Anatomy 0.000 description 3
- 238000000338 in vitro Methods 0.000 description 3
- 239000010410 layer Substances 0.000 description 3
- 210000000653 nervous system Anatomy 0.000 description 3
- 210000003061 neural cell Anatomy 0.000 description 3
- 230000001537 neural effect Effects 0.000 description 3
- 239000012679 serum free medium Substances 0.000 description 3
- 102100024785 Fibroblast growth factor 2 Human genes 0.000 description 2
- 108090000379 Fibroblast growth factor 2 Proteins 0.000 description 2
- 230000030833 cell death Effects 0.000 description 2
- 230000018109 developmental process Effects 0.000 description 2
- 210000001705 ectoderm cell Anatomy 0.000 description 2
- 239000003102 growth factor Substances 0.000 description 2
- 239000003550 marker Substances 0.000 description 2
- 210000001178 neural stem cell Anatomy 0.000 description 2
- 210000004498 neuroglial cell Anatomy 0.000 description 2
- 208000023275 Autoimmune disease Diseases 0.000 description 1
- 208000027205 Congenital disease Diseases 0.000 description 1
- 101000595198 Homo sapiens Podocalyxin Proteins 0.000 description 1
- 102000012411 Intermediate Filament Proteins Human genes 0.000 description 1
- 108010061998 Intermediate Filament Proteins Proteins 0.000 description 1
- 102000008730 Nestin Human genes 0.000 description 1
- 108010088225 Nestin Proteins 0.000 description 1
- 102000007354 PAX6 Transcription Factor Human genes 0.000 description 1
- 108010032788 PAX6 Transcription Factor Proteins 0.000 description 1
- 102100036031 Podocalyxin Human genes 0.000 description 1
- 102000013127 Vimentin Human genes 0.000 description 1
- 108010065472 Vimentin Proteins 0.000 description 1
- 239000005557 antagonist Substances 0.000 description 1
- 210000002459 blastocyst Anatomy 0.000 description 1
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000004289 cerebral ventricle Anatomy 0.000 description 1
- 239000012141 concentrate Substances 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 230000001939 inductive effect Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000012528 membrane Substances 0.000 description 1
- 210000005055 nestin Anatomy 0.000 description 1
- 230000004770 neurodegeneration Effects 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 210000002569 neuron Anatomy 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 230000007170 pathology Effects 0.000 description 1
- 210000001778 pluripotent stem cell Anatomy 0.000 description 1
- 230000035755 proliferation Effects 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 108090000623 proteins and genes Proteins 0.000 description 1
- 208000020016 psychiatric disease Diseases 0.000 description 1
- 230000008929 regeneration Effects 0.000 description 1
- 238000011069 regeneration method Methods 0.000 description 1
- 239000002356 single layer Substances 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000025366 tissue development Effects 0.000 description 1
- 238000002054 transplantation Methods 0.000 description 1
- 230000008733 trauma Effects 0.000 description 1
- 230000002792 vascular Effects 0.000 description 1
- 210000005048 vimentin Anatomy 0.000 description 1
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/970,543 US7011828B2 (en) | 2000-03-14 | 2001-10-04 | Implanting neural progenitor cells derived for human embryonic stem cells |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008101883A Division JP2008201792A (ja) | 2001-10-04 | 2008-04-09 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2004248507A JP2004248507A (ja) | 2004-09-09 |
| JP2004248507A5 true JP2004248507A5 (enExample) | 2006-02-23 |
Family
ID=25517110
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2002292682A Withdrawn JP2004248507A (ja) | 2001-10-04 | 2002-10-04 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
| JP2008101883A Pending JP2008201792A (ja) | 2001-10-04 | 2008-04-09 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2008101883A Pending JP2008201792A (ja) | 2001-10-04 | 2008-04-09 | 胚性幹細胞と胚性幹細胞由来の神経前駆細胞 |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US7011828B2 (enExample) |
| EP (1) | EP1302536A3 (enExample) |
| JP (2) | JP2004248507A (enExample) |
| AU (1) | AU2002301347B2 (enExample) |
| CA (1) | CA2406610A1 (enExample) |
| IL (1) | IL152106A0 (enExample) |
| SG (1) | SG144689A1 (enExample) |
Families Citing this family (45)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2453010A1 (en) * | 2000-03-14 | 2012-05-16 | ES Cell International Pte Ltd. | Neural progenitor cells derived from embryonic stem cells |
| US20080268054A1 (en) * | 2000-12-04 | 2008-10-30 | Eugene Bell | Dermal derived human stem cells and compositions and methods thereof |
| US7566101B2 (en) * | 2002-07-15 | 2009-07-28 | Hennessy Industries, Inc. | Vehicle wheel balance weights |
| WO2004099395A2 (en) * | 2003-05-08 | 2004-11-18 | Cellartis Ab | A method for the generation of neural progenitor cells |
| WO2004099394A2 (en) * | 2003-05-08 | 2004-11-18 | Cellartis Ab | A method for efficient transfer of human blastocyst-derived stem cells (hbs cells) from a feeder-supported to a feeder-free culture system |
| JP4389037B2 (ja) * | 2003-06-03 | 2009-12-24 | 独立行政法人理化学研究所 | Es細胞の電気パルス処理によって得られた神経細胞 |
| AU2005250322A1 (en) * | 2004-04-09 | 2005-12-15 | Ronald S. Goldstein | Methods for generating neuronal cells from human embryonic stem cells and uses thereof |
| WO2005100551A1 (en) * | 2004-04-13 | 2005-10-27 | Sungkwang Educational Foundation | In vitro method for isolating, proliferating and differentiating germ-line stem cells |
| US7622108B2 (en) | 2004-04-23 | 2009-11-24 | Bioe, Inc. | Multi-lineage progenitor cells |
| ATE506431T1 (de) | 2004-04-23 | 2011-05-15 | Bioe Llc | Mehrfachlinien-vorläuferzellen |
| JP2006149329A (ja) * | 2004-12-01 | 2006-06-15 | Univ Of Tokyo | 繊毛上皮細胞調製方法 |
| JP2006204292A (ja) * | 2004-12-27 | 2006-08-10 | Asahi Kasei Corp | ヒト胚性幹細胞分化抑制剤 |
| WO2006086746A2 (en) * | 2005-02-09 | 2006-08-17 | Burnham Institute For Medical Research | Homogeneous neural precursor cells |
| US9295543B2 (en) * | 2005-03-17 | 2016-03-29 | Stratatech Corporation | Skin substitutes with improved purity |
| US8999706B2 (en) * | 2005-04-12 | 2015-04-07 | The Trustees Of The University Of Pennsylvania | Methods for preparation of human hair-follicle derived multipotent adult stem cells |
| BRPI0617084A2 (pt) * | 2005-09-02 | 2011-07-12 | Agency Science Tech & Res | método, linhagem de célula progenitora, célula diferenciada e método para gerar uma célula diferenciada de uma célula-tronco (es) embrionária |
| ITNA20060017A1 (it) * | 2006-02-20 | 2007-08-21 | Aquino Riccardo D | Tecnica di prelievo e selezione di un una popolazione di cellule staminali di tipo embrionale da tessuti follicolari peridentari di uomo adulto. |
| US7727763B2 (en) | 2006-04-17 | 2010-06-01 | Bioe, Llc | Differentiation of multi-lineage progenitor cells to respiratory epithelial cells |
| US20080003681A1 (en) * | 2006-06-28 | 2008-01-03 | Mahalaxmi Gita Bangera | Methods for altering cellular susceptibility to infection |
| GB0622394D0 (en) | 2006-11-09 | 2006-12-20 | Univ Cambridge Tech | Differentiation of pluripotent cells |
| RU2341270C2 (ru) * | 2006-12-28 | 2008-12-20 | Александр Сергеевич Ботин | Композиция для стимулирования роста и регенерации клеток, а также способы ее получения |
| CN101835479A (zh) * | 2007-07-25 | 2010-09-15 | 佰欧益有限公司 | 多系祖细胞分化为软骨细胞 |
| US8338176B2 (en) * | 2007-07-30 | 2012-12-25 | The Board Of Trustees Of The Leland Stanford Junior University | Derivation of neural stem cells from embryonic stem cells |
| EP2185694A2 (en) | 2007-08-02 | 2010-05-19 | California Stem Cell, Inc. | Neuronal progenitor cells and methods of derivation and purification of neuronal progenitor cells from embryonic stem cells |
| KR101175175B1 (ko) * | 2008-07-28 | 2012-08-20 | 서울대학교병원 | 인간 줄기세포에서 고활성 줄기세포를 분리하는 방법 및상기 방법에 의해 분리된 고활성 줄기 세포 |
| US8642334B2 (en) | 2009-02-17 | 2014-02-04 | Memorial Sloan Kettering Cancer Center | Methods of neural conversion of human embryonic stem cells |
| JP5783504B2 (ja) * | 2009-03-30 | 2015-09-24 | 国立研究開発法人国立環境研究所 | 胎生プログラミングに対する影響を評価するための方法 |
| US20110052549A1 (en) * | 2009-08-27 | 2011-03-03 | The Regents Of The University Of California | Cell culture device to differentiate stem cells in a specific orientation |
| JP2013506681A (ja) | 2009-10-02 | 2013-02-28 | バクスター・インターナショナル・インコーポレイテッド | 腎損傷の処置における使用のための造血幹細胞 |
| JP2011121949A (ja) | 2009-12-14 | 2011-06-23 | Kyoto Univ | 筋萎縮性側索硬化症の予防および治療用医薬組成物 |
| EP4245370A3 (en) | 2010-07-12 | 2023-11-29 | University of Southern California | Biocompatible substrate for facilitating interconnections between stem cells and target tissues and methods for implanting same |
| EP2633036A4 (en) * | 2010-10-26 | 2013-12-04 | Univ Case Western Reserve | DIFFERENTIATION METHOD FOR THE PRODUCTION OF GLIA CELL POPULATIONS |
| US9487752B2 (en) * | 2011-03-30 | 2016-11-08 | Cellular Dynamics International, Inc. | Priming of pluripotent stem cells for neural differentiation |
| US10478206B2 (en) | 2011-04-29 | 2019-11-19 | University Of Southern California | Instruments and methods for the implantation of cell-seeded substrates |
| US8877489B2 (en) | 2011-12-05 | 2014-11-04 | California Institute Of Technology | Ultrathin parylene-C semipermeable membranes for biomedical applications |
| CN110684734A (zh) | 2011-11-04 | 2020-01-14 | 纪念斯隆-凯特琳癌症中心 | 用于植入的中脑多巴胺(da)神经元 |
| US9248013B2 (en) | 2011-12-05 | 2016-02-02 | California Institute Of Technology | 3-Dimensional parylene scaffold cage |
| WO2013126590A2 (en) | 2012-02-21 | 2013-08-29 | Baxter International Inc. | Pharmaceutical composition comprising cd34+ cells |
| JP6335117B2 (ja) | 2012-03-21 | 2018-05-30 | 国立大学法人京都大学 | アルツハイマー病の治療薬および/または予防薬のスクリーニング方法 |
| KR102073111B1 (ko) * | 2012-10-16 | 2020-02-04 | 메르츠 파마 게엠베하 운트 코. 카가아 | 신경독소 폴리펩티드의 생물학적 활성의 결정을 위한 세포 테스트 시스템 |
| JP2016520291A (ja) | 2013-03-14 | 2016-07-14 | ザ リージェンツ オブ ザ ユニバーシティ オブ カリフォルニア | invitroでの内側神経節隆起前駆細胞の作製 |
| EP3498824A1 (en) | 2013-04-26 | 2019-06-19 | Memorial Sloan-Kettering Cancer Center | Cortical interneurons and other neuronal cells produced by the directed differentiation of pluripotent and multipotent cells |
| CA2931334A1 (en) | 2013-11-21 | 2015-05-28 | Memorial Sloan-Kettering Cancer Center | Specification of functional cranial placode derivatives from human pluripotent stem cells |
| JP6329468B2 (ja) * | 2014-09-16 | 2018-05-23 | 三菱製紙株式会社 | 線維芽細胞のガラス化凍結保存方法 |
| WO2016101017A1 (en) | 2014-12-24 | 2016-06-30 | Neuorphan Pty Ltd | Improvements in oligodendroglial cell culturing methods and in methods for treating neurodegenerative disorders by using thyroid hormones or analogues |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5968829A (en) * | 1997-09-05 | 1999-10-19 | Cytotherapeutics, Inc. | Human CNS neural stem cells |
| DE19756864C5 (de) | 1997-12-19 | 2014-07-10 | Oliver Brüstle | Neurale Vorläuferzellen, Verfahren zu ihrer Herstellung und ihre Verwendung zur Therapie von neuralen Defekten |
| EP1129176A4 (en) * | 1998-11-09 | 2002-10-30 | Es Cell Int Pte Ltd | EMBRYONIC STEM CELLS |
| EP2453010A1 (en) | 2000-03-14 | 2012-05-16 | ES Cell International Pte Ltd. | Neural progenitor cells derived from embryonic stem cells |
| AU779694B2 (en) * | 2000-03-14 | 2005-02-03 | Es Cell International Pte Ltd | Embryonic stem cells and neural progenitor cells derived therefrom |
| AU2001263199B2 (en) * | 2000-05-17 | 2004-09-16 | Asterias Biotherapeutics, Inc. | Neural progenitor cell populations |
-
2001
- 2001-10-04 US US09/970,543 patent/US7011828B2/en not_active Expired - Lifetime
-
2002
- 2002-10-03 IL IL15210602A patent/IL152106A0/xx unknown
- 2002-10-03 CA CA002406610A patent/CA2406610A1/en not_active Abandoned
- 2002-10-04 JP JP2002292682A patent/JP2004248507A/ja not_active Withdrawn
- 2002-10-04 AU AU2002301347A patent/AU2002301347B2/en not_active Ceased
- 2002-10-04 SG SG200206039-0A patent/SG144689A1/en unknown
- 2002-10-04 EP EP02256974A patent/EP1302536A3/en not_active Withdrawn
-
2008
- 2008-04-09 JP JP2008101883A patent/JP2008201792A/ja active Pending
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