JP2003531798A5 - - Google Patents
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- Publication number
- JP2003531798A5 JP2003531798A5 JP2001579712A JP2001579712A JP2003531798A5 JP 2003531798 A5 JP2003531798 A5 JP 2003531798A5 JP 2001579712 A JP2001579712 A JP 2001579712A JP 2001579712 A JP2001579712 A JP 2001579712A JP 2003531798 A5 JP2003531798 A5 JP 2003531798A5
- Authority
- JP
- Japan
- Prior art keywords
- calcium phosphate
- composition
- solution
- solidifies
- calcium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 229910000389 calcium phosphate Inorganic materials 0.000 description 19
- 239000001506 calcium phosphate Substances 0.000 description 19
- 235000011010 calcium phosphates Nutrition 0.000 description 19
- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 19
- 238000000034 method Methods 0.000 description 13
- BPQQTUXANYXVAA-UHFFFAOYSA-N Orthosilicate Chemical compound [O-][Si]([O-])([O-])[O-] BPQQTUXANYXVAA-UHFFFAOYSA-N 0.000 description 12
- 239000000376 reactant Substances 0.000 description 11
- 230000009969 flowable effect Effects 0.000 description 10
- OYPRJOBELJOOCE-UHFFFAOYSA-N Calcium Chemical compound [Ca] OYPRJOBELJOOCE-UHFFFAOYSA-N 0.000 description 6
- 229910019142 PO4 Inorganic materials 0.000 description 6
- 239000011575 calcium Substances 0.000 description 6
- 229910052791 calcium Inorganic materials 0.000 description 6
- 239000004568 cement Substances 0.000 description 6
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 description 6
- 239000010452 phosphate Substances 0.000 description 6
- 230000007547 defect Effects 0.000 description 5
- 230000004888 barrier function Effects 0.000 description 4
- 239000004115 Sodium Silicate Substances 0.000 description 2
- 229910052586 apatite Inorganic materials 0.000 description 2
- 238000004519 manufacturing process Methods 0.000 description 2
- 239000000463 material Substances 0.000 description 2
- VSIIXMUUUJUKCM-UHFFFAOYSA-D pentacalcium;fluoride;triphosphate Chemical compound [F-].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O VSIIXMUUUJUKCM-UHFFFAOYSA-D 0.000 description 2
- NTHWMYGWWRZVTN-UHFFFAOYSA-N sodium silicate Chemical group [Na+].[Na+].[O-][Si]([O-])=O NTHWMYGWWRZVTN-UHFFFAOYSA-N 0.000 description 2
- 229910052911 sodium silicate Inorganic materials 0.000 description 2
- 210000001519 tissue Anatomy 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 1
- 210000003625 skull Anatomy 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US09/561,324 US6375935B1 (en) | 2000-04-28 | 2000-04-28 | Calcium phosphate cements prepared from silicate solutions |
| US09/561,324 | 2000-04-28 | ||
| PCT/US2001/013853 WO2001082834A1 (en) | 2000-04-28 | 2001-04-27 | Calcium phosphate cements prepared from silicate solutions |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| JP2003531798A JP2003531798A (ja) | 2003-10-28 |
| JP2003531798A5 true JP2003531798A5 (enExample) | 2008-06-05 |
| JP4996030B2 JP4996030B2 (ja) | 2012-08-08 |
Family
ID=24241486
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001579712A Expired - Fee Related JP4996030B2 (ja) | 2000-04-28 | 2001-04-27 | ケイ酸塩溶液から調製されるリン酸カルシウムセメント |
Country Status (9)
| Country | Link |
|---|---|
| US (2) | US6375935B1 (enExample) |
| EP (1) | EP1284680B1 (enExample) |
| JP (1) | JP4996030B2 (enExample) |
| AT (1) | ATE408384T1 (enExample) |
| AU (2) | AU5925101A (enExample) |
| CA (1) | CA2407115C (enExample) |
| DE (1) | DE60135841D1 (enExample) |
| ES (1) | ES2313958T3 (enExample) |
| WO (1) | WO2001082834A1 (enExample) |
Families Citing this family (40)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7820191B2 (en) * | 2000-04-28 | 2010-10-26 | Skeletal Kinetics, Llc | Calcium phosphate cements prepared from silicate solutions |
| US6375935B1 (en) * | 2000-04-28 | 2002-04-23 | Brent R. Constantz | Calcium phosphate cements prepared from silicate solutions |
| IL153699A (en) | 2002-12-26 | 2008-11-26 | Prochon Biotech Ltd | The composition for transplantation basically |
| US7507257B2 (en) * | 2003-02-04 | 2009-03-24 | Wright Medical Technology, Inc. | Injectable resorbable bone graft material, powder for forming same and methods relating thereto for treating bone defects |
| US20040250730A1 (en) * | 2003-06-12 | 2004-12-16 | David Delaney | Calcium phosphate cements prepared from silicate-phosphate solutions |
| JP2007524635A (ja) * | 2003-07-02 | 2007-08-30 | エーディーエー ファウンデーション | 再石灰化作用のある歯科用セメント |
| US7306786B2 (en) * | 2003-07-28 | 2007-12-11 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising a water-soluble contrast agent |
| US7261717B2 (en) | 2003-09-11 | 2007-08-28 | Skeletal Kinetics Llc | Methods and devices for delivering orthopedic cements to a target bone site |
| US7261718B2 (en) | 2003-09-11 | 2007-08-28 | Skeletal Kinetics Llc | Use of vibration with polymeric bone cements |
| US7252833B2 (en) * | 2003-11-18 | 2007-08-07 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising an osteoclastogenic agent |
| US20050123490A1 (en) * | 2003-12-04 | 2005-06-09 | Kazue Yamagishi | Composition and method for prevention and treatment of dental caries |
| US8118812B2 (en) | 2004-03-09 | 2012-02-21 | Skeletal Kinetics, Llc | Use of vibration in composite fixation |
| US9707024B2 (en) | 2004-03-09 | 2017-07-18 | Skeletal Kinetics, Llc | Use of vibration in composite fixation |
| US20050257714A1 (en) * | 2004-05-20 | 2005-11-24 | Constantz Brent R | Orthopedic cements comprising a barium apatite contrast agent |
| US7252841B2 (en) * | 2004-05-20 | 2007-08-07 | Skeletal Kinetics, Llc | Rapid setting calcium phosphate cements |
| US7175858B2 (en) * | 2004-07-26 | 2007-02-13 | Skeletal Kinetics Llc | Calcium phosphate cements and methods for using the same |
| ES2246726B2 (es) | 2004-08-12 | 2007-11-01 | Universitat Politecnica De Catalunya | Espuma de fosfato de calcio autofraguable e inyectable. |
| DE102004041354A1 (de) * | 2004-08-25 | 2006-03-30 | Buck, Alfred | Implantat für den chirurgischen Einsatz bei Menschen oder Wirbeltieren |
| EP1804814B1 (en) * | 2004-09-21 | 2013-12-11 | Thomas Joseph Lally | Multi-purpose bio-material composition |
| US7459018B2 (en) * | 2005-04-08 | 2008-12-02 | Howmedica Leibinger Inc. | Injectable calcium phosphate cement |
| US7416602B2 (en) * | 2005-04-08 | 2008-08-26 | Howmedica Leibinger, Inc. | Calcium phosphate cement |
| US8921109B2 (en) | 2005-09-19 | 2014-12-30 | Histogenics Corporation | Cell-support matrix having narrowly defined uniformly vertically and non-randomly organized porosity and pore density and a method for preparation thereof |
| US9125966B2 (en) * | 2005-11-15 | 2015-09-08 | Dr. H.C. Robert Mathys Stiftung | Bone repair material |
| US7833270B2 (en) * | 2006-05-05 | 2010-11-16 | Warsaw Orthopedic, Inc | Implant depots to deliver growth factors to treat osteoporotic bone |
| US7699928B2 (en) * | 2006-07-14 | 2010-04-20 | Grancrete, Inc. | Sprayable and pumpable phosphate cement |
| US20080066656A1 (en) * | 2006-09-18 | 2008-03-20 | General Redi-Chem, Inc. | Integral Sealer Admixture Composition For Improving The Performance Of Concrete And Other Cementitious Systems, Mixtures, And Products |
| US7658940B2 (en) * | 2007-03-30 | 2010-02-09 | Skeletal Kinetics, Llc | Calcium phosphate cements comprising autologous bone |
| US20100090168A1 (en) * | 2008-10-06 | 2010-04-15 | Grancrete, Inc. | Radiation shielding structure composition |
| US8273172B2 (en) | 2008-10-07 | 2012-09-25 | Grancrete, Inc. | Heat resistant phosphate cement |
| US8409538B2 (en) | 2008-12-04 | 2013-04-02 | Skeletal Kinetics Llc | Tricalcium phosphate coarse particle compositions and methods for making the same |
| US8673364B2 (en) | 2009-09-28 | 2014-03-18 | Skeletal Kinetics, Llc | Rapid setting high strength calcium phosphate cements comprising cyclodextrins |
| EP2352458A4 (en) * | 2008-12-04 | 2013-08-28 | Skeletal Kinetics Llc | TRICALCIUM PHOSPHATE GROWING PARTICLE COMPOSITIONS AND METHODS OF MAKING THE SAME |
| US20130189337A1 (en) * | 2010-10-06 | 2013-07-25 | Kuraray Noritake Dental Inc. | Dentinal tubule sealant and method for producing the same |
| EP2637983B1 (en) | 2010-11-10 | 2018-12-26 | Stryker European Holdings I, LLC | Process for the preparation of a polymeric bone foam |
| US10077420B2 (en) | 2014-12-02 | 2018-09-18 | Histogenics Corporation | Cell and tissue culture container |
| DE102015107976A1 (de) | 2015-05-20 | 2016-11-24 | Beatrice Saier | Dosiereinrichtung u.a. |
| WO2017011448A1 (en) | 2015-07-13 | 2017-01-19 | Bone Solutions, Inc. | Bio-material composition and methods of use |
| US10105289B2 (en) | 2016-05-26 | 2018-10-23 | Essential Dental Systems, Inc. | Biomimetic mineral based endodontic cement composition and uses thereof |
| CN113979729B (zh) * | 2021-11-15 | 2022-09-20 | 上海师范大学 | 一种锂硅化合物增强生物活性陶瓷材料及其制备方法 |
| JP2024021585A (ja) * | 2022-08-04 | 2024-02-16 | 国立研究開発法人産業技術総合研究所 | シリカ－リン酸カルシウム複合ブロック体、及びシリカ－リン酸カルシウム複合ブロック体の製造方法 |
Family Cites Families (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5370097A (en) | 1976-12-03 | 1978-06-22 | Central Glass Co Ltd | Purifying method for crude sodium silicofluoride |
| JPS5395196A (en) | 1977-02-01 | 1978-08-19 | Central Glass Co Ltd | Production of purified sodium silicofluoride |
| US4165368A (en) * | 1977-07-01 | 1979-08-21 | Colgate Palmolive Company | Dental prophylactic paste |
| EP0006414B1 (de) | 1978-06-29 | 1984-10-10 | Osteo Ag | Mit Kohlenstoffasern verstärkter Knochenzement |
| JPS5654841A (en) | 1979-10-08 | 1981-05-15 | Mitsubishi Mining & Cement Co | Bone broken portion and filler for void portion and method of treating bone of animal using said filler |
| JPS6017118A (ja) | 1983-07-06 | 1985-01-29 | Mitsubishi Mining & Cement Co Ltd | リン酸カルシウム質フアイバ− |
| JPH0643582B2 (ja) * | 1986-06-11 | 1994-06-08 | 強化土エンジニヤリング株式会社 | 地盤注入用薬液 |
| US6005162A (en) | 1988-04-20 | 1999-12-21 | Norian Corporation | Methods of repairing bone |
| US5962028A (en) | 1988-04-20 | 1999-10-05 | Norian Corporation | Carbonated hydroxyapatite compositions and uses |
| US4990163A (en) | 1989-02-06 | 1991-02-05 | Trustees Of The University Of Pennsylvania | Method of depositing calcium phosphate cermamics for bone tissue calcification enhancement |
| US5460803A (en) | 1989-05-24 | 1995-10-24 | American Dental Association Health Foundation | Methods and compositions for mineralizing and fluoridating calcified tissues |
| US5534244A (en) | 1989-05-24 | 1996-07-09 | Tung; Ming S. | Methods and compositions for mineralizing and/or fluoridating calcified tissues with amorphous strontium compounds |
| US6000341A (en) | 1989-05-24 | 1999-12-14 | American Dental Association Health Foundation | Methods and composition for mineralizing and fluoridating calcified tissues |
| US5561173A (en) | 1990-06-19 | 1996-10-01 | Carolyn M. Dry | Self-repairing, reinforced matrix materials |
| JPH05124919A (ja) | 1991-11-05 | 1993-05-21 | Sangi Co Ltd | 抗菌性セラミツクス |
| US5605713A (en) | 1991-11-22 | 1997-02-25 | Boltong; Maria G. | Process for the preparation of calcium phosphate cements and its application as bio-materials |
| US5218035A (en) | 1992-02-03 | 1993-06-08 | Liu Sung Tsuen | Phosphate-containing surgical cements |
| US5281265A (en) | 1992-02-03 | 1994-01-25 | Liu Sung Tsuen | Resorbable surgical cements |
| GB9202248D0 (en) | 1992-02-03 | 1992-03-18 | Howmedica | Prosthesis for attachement without bone cement and method of attaching |
| US5522893A (en) | 1993-03-12 | 1996-06-04 | American Dental Association Health Foundation | Calcium phosphate hydroxyapatite precursor and methods for making and using the same |
| US5565502A (en) | 1993-03-24 | 1996-10-15 | Children's Medical Center Corporation | Isolation of the calcium-phosphate crystals of bone |
| US5427768A (en) | 1993-06-23 | 1995-06-27 | American Dental Association Health Foundation | Carbonated solutions for treating, mineralizing and fluoridating calcified tissues and methods for their use |
| AU7363694A (en) | 1993-07-22 | 1995-02-20 | Norian Corporation | Storage stable partially neutralized acid compositions and uses |
| WO1995008304A1 (en) | 1993-09-21 | 1995-03-30 | The Penn State Research Foundation | Bone substitute composition comprising hydroxyapatite and a method of production therefor |
| US5525148A (en) | 1993-09-24 | 1996-06-11 | American Dental Association Health Foundation | Self-setting calcium phosphate cements and methods for preparing and using them |
| CA2143733A1 (en) | 1994-03-02 | 1995-09-03 | Yoshikazu Umezu | Alpha-tricalcium phosphate ceramic and production method thereof |
| US5626861A (en) | 1994-04-01 | 1997-05-06 | Massachusetts Institute Of Technology | Polymeric-hydroxyapatite bone composite |
| US5817327A (en) | 1994-07-27 | 1998-10-06 | The Trustees Of The University Of Pennsylvania | Incorporation of biologically active molecules into bioactive glasses |
| US5496399A (en) | 1994-08-23 | 1996-03-05 | Norian Corporation | Storage stable calcium phosphate cements |
| FI104881B (fi) | 1994-10-06 | 2000-04-28 | Bioxid Oy | Uusien bioaktiivista piipitoista lasia sisältävien koostumusten valmistusmenetelmä |
| WO1996011715A1 (en) | 1994-10-13 | 1996-04-25 | Kuraray Co., Ltd. | Hard-tissue repair composition and supply unit therefor |
| US6132463A (en) | 1995-05-19 | 2000-10-17 | Etex Corporation | Cell seeding of ceramic compositions |
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| US5783248A (en) | 1995-08-28 | 1998-07-21 | National Science Council Of R.O.C. | Process for producing a bioceramic composite material containing natural bone material on an alumina substrate |
| JP4465046B2 (ja) | 1995-09-01 | 2010-05-19 | ワルソー・オーソペディック，インコーポレイテッド | 特に骨細胞活性を支持する様に調整されたリン酸カルシウム相の人工安定化組成物 |
| US5648097A (en) | 1995-10-04 | 1997-07-15 | Biotek, Inc. | Calcium mineral-based microparticles and method for the production thereof |
| US5681872A (en) | 1995-12-07 | 1997-10-28 | Orthovita, Inc. | Bioactive load bearing bone graft compositions |
| GB2316940A (en) | 1996-08-30 | 1998-03-11 | Queen Mary & Westfield College | Silicon-substituted hydroxyapatite |
| US5914356A (en) | 1996-12-06 | 1999-06-22 | Orthovita, Inc. | Bioactive load bearing bone bonding compositions |
| ES2252801T3 (es) * | 1996-12-13 | 2006-05-16 | Norian Corporation | Dispositivo para el alamacenaje y mezcla de cementos. |
| JP4271733B2 (ja) * | 1996-12-13 | 2009-06-03 | ノリアン コーポレイション | セメントの調製、保存、および投与 |
| US5875799A (en) | 1997-09-23 | 1999-03-02 | Advanced Medical Instruments, Inc. | Therapeutic dental floss for treating systemic diseases |
| JPH11106251A (ja) * | 1997-09-30 | 1999-04-20 | Taiheiyo Cement Corp | 硬化体の製造方法 |
| US5968253A (en) | 1998-07-31 | 1999-10-19 | Norian Corporation | Calcium phosphate cements comprising antimicrobial agents |
| ES2185227T3 (es) * | 1998-10-19 | 2003-04-16 | Synthes Ag | Cemento hidraulico ceramico que endurece. |
| US6398859B1 (en) | 1998-12-24 | 2002-06-04 | American Dental Association Health Foundation | Resin-based pulp capping and basing cements |
| US6379453B1 (en) | 1999-07-14 | 2002-04-30 | Jiin-Huey Chern | Process for producing fast-setting, bioresorbable calcium phosphate cements |
| US6458423B1 (en) | 1999-08-03 | 2002-10-01 | David M. Goodson | Sprayable phosphate cementitious coatings and a method and apparatus for the production thereof |
| US6451059B1 (en) | 1999-11-12 | 2002-09-17 | Ethicon, Inc. | Viscous suspension spinning process for producing resorbable ceramic fibers and scaffolds |
| US6375935B1 (en) * | 2000-04-28 | 2002-04-23 | Brent R. Constantz | Calcium phosphate cements prepared from silicate solutions |
| US6518212B1 (en) | 2000-09-18 | 2003-02-11 | The University Of Chicago | Chemically bonded phospho-silicate ceramics |
-
2000
- 2000-04-28 US US09/561,324 patent/US6375935B1/en not_active Expired - Lifetime
-
2001
- 2001-04-27 AT AT01932749T patent/ATE408384T1/de not_active IP Right Cessation
- 2001-04-27 JP JP2001579712A patent/JP4996030B2/ja not_active Expired - Fee Related
- 2001-04-27 DE DE60135841T patent/DE60135841D1/de not_active Expired - Lifetime
- 2001-04-27 AU AU5925101A patent/AU5925101A/xx active Pending
- 2001-04-27 WO PCT/US2001/013853 patent/WO2001082834A1/en not_active Ceased
- 2001-04-27 ES ES01932749T patent/ES2313958T3/es not_active Expired - Lifetime
- 2001-04-27 EP EP01932749A patent/EP1284680B1/en not_active Expired - Lifetime
- 2001-04-27 CA CA2407115A patent/CA2407115C/en not_active Expired - Lifetime
- 2001-04-27 AU AU2001259251A patent/AU2001259251B2/en not_active Ceased
-
2002
- 2002-03-29 US US10/109,994 patent/US6719993B2/en not_active Expired - Lifetime
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