JP2003531587A - 精神分裂病関連遺伝子 - Google Patents

精神分裂病関連遺伝子

Info

Publication number
JP2003531587A
JP2003531587A JP2001572867A JP2001572867A JP2003531587A JP 2003531587 A JP2003531587 A JP 2003531587A JP 2001572867 A JP2001572867 A JP 2001572867A JP 2001572867 A JP2001572867 A JP 2001572867A JP 2003531587 A JP2003531587 A JP 2003531587A
Authority
JP
Japan
Prior art keywords
seq
schizophrenia
group
polynucleotide
fragment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001572867A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003531587A5 (enExample
Inventor
コクラン、スーザン
パターソン、ギャリー
良孝 大橋
モリス、ブライアン
プラット、ジュディス
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tanabe Pharma Corp
Original Assignee
Mitsubishi Pharma Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB0007880A external-priority patent/GB0007880D0/en
Priority claimed from GB0012768A external-priority patent/GB0012768D0/en
Application filed by Mitsubishi Pharma Corp filed Critical Mitsubishi Pharma Corp
Publication of JP2003531587A publication Critical patent/JP2003531587A/ja
Publication of JP2003531587A5 publication Critical patent/JP2003531587A5/ja
Withdrawn legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K49/00—Preparations for testing in vivo
    • A61K49/0004—Screening or testing of compounds for diagnosis of disorders, assessment of conditions, e.g. renal clearance, gastric emptying, testing for diabetes, allergy, rheuma, pancreas functions
    • A61K49/0008—Screening agents using (non-human) animal models or transgenic animal models or chimeric hosts, e.g. Alzheimer disease animal model, transgenic model for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K2217/00—Genetically modified animals
    • A01K2217/05—Animals comprising random inserted nucleic acids (transgenic)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/136—Screening for pharmacological compounds
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Toxicology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Biomedical Technology (AREA)
  • Veterinary Medicine (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Epidemiology (AREA)
  • Urology & Nephrology (AREA)
  • General Engineering & Computer Science (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
JP2001572867A 2000-03-31 2001-04-02 精神分裂病関連遺伝子 Withdrawn JP2003531587A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
GB0007880A GB0007880D0 (en) 2000-03-31 2000-03-31 Schizophrenia related genes
GB0007880.8 2000-03-31
GB0012768.8 2000-05-26
GB0012768A GB0012768D0 (en) 2000-05-26 2000-05-26 Schizophrenia related genes
PCT/GB2001/001486 WO2001075440A2 (en) 2000-03-31 2001-04-02 Schizophrenia related genes

Publications (2)

Publication Number Publication Date
JP2003531587A true JP2003531587A (ja) 2003-10-28
JP2003531587A5 JP2003531587A5 (enExample) 2008-04-03

Family

ID=26244008

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001572867A Withdrawn JP2003531587A (ja) 2000-03-31 2001-04-02 精神分裂病関連遺伝子

Country Status (5)

Country Link
US (2) US20030175741A1 (enExample)
EP (1) EP1356284A2 (enExample)
JP (1) JP2003531587A (enExample)
AU (1) AU2001244358A1 (enExample)
WO (1) WO2001075440A2 (enExample)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3507884B2 (ja) * 2000-03-07 2004-03-15 新潟大学長 遺伝子発現を指標とする統合失調症の客観的診断法
AU2002211502A1 (en) * 2000-10-04 2002-04-15 Curagen Corporation Novel proteins and nucleic acids encoding same and antibodies directed against these proteins
AU2001293870A1 (en) * 2000-10-16 2002-04-29 Bayer Aktiengesellschaft Regulation of human netrin binding membrane receptor unc5h-1
AU2003250033A1 (en) * 2002-07-11 2004-02-02 Novartis Ag Genes associated with schizophrenia, adhd and bipolar disorders
JP2004135667A (ja) * 2002-09-27 2004-05-13 Japan Science & Technology Agency 血液を用いた統合失調症の診断方法
WO2004031235A1 (en) * 2002-10-07 2004-04-15 Bayer Healthcare Ag Regulation of human calcium-independent alpha-latrotoxin receptor
GB0712524D0 (en) * 2007-06-28 2007-08-08 Mitsubishi Pharma Corp Novel schizophrenia associated genes
US20110136738A1 (en) * 2008-02-15 2011-06-09 University College Dublin, National University Of Ireland, Dublin Alternatively Transcribed Genes Associated with Schizophrenia
WO2010028133A1 (en) * 2008-09-03 2010-03-11 Northeastern University Imaging neuroleptic compounds

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6630345B2 (en) * 1997-03-04 2003-10-07 New York University Nucleic acids encoding a calcium independent receptor of α-latrotoxin, characterization and uses thereof
WO1999007739A2 (en) * 1997-08-06 1999-02-18 The Rockefeller University Dna encoding the human synapsin iii gene and uses thereof
JP3507884B2 (ja) * 2000-03-07 2004-03-15 新潟大学長 遺伝子発現を指標とする統合失調症の客観的診断法

Also Published As

Publication number Publication date
WO2001075440A3 (en) 2003-04-24
AU2001244358A1 (en) 2001-10-15
US20070074295A1 (en) 2007-03-29
WO2001075440A2 (en) 2001-10-11
EP1356284A2 (en) 2003-10-29
US20030175741A1 (en) 2003-09-18

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