JP2003531129A5 - - Google Patents

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Publication number
JP2003531129A5
JP2003531129A5 JP2001576078A JP2001576078A JP2003531129A5 JP 2003531129 A5 JP2003531129 A5 JP 2003531129A5 JP 2001576078 A JP2001576078 A JP 2001576078A JP 2001576078 A JP2001576078 A JP 2001576078A JP 2003531129 A5 JP2003531129 A5 JP 2003531129A5
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JP
Japan
Prior art keywords
seq
pharmaceutical composition
immunoglobulin
antigen
binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
JP2001576078A
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English (en)
Japanese (ja)
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JP2003531129A (ja
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Publication date
Priority claimed from US09/748,960 external-priority patent/US20010046496A1/en
Application filed filed Critical
Publication of JP2003531129A publication Critical patent/JP2003531129A/ja
Publication of JP2003531129A5 publication Critical patent/JP2003531129A5/ja
Withdrawn legal-status Critical Current

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JP2001576078A 2000-04-14 2001-04-13 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用 Withdrawn JP2003531129A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US55008200A 2000-04-14 2000-04-14
US09/550,082 2000-04-14
US09/748,960 2000-12-27
US09/748,960 US20010046496A1 (en) 2000-04-14 2000-12-27 Method of administering an antibody
PCT/US2001/012234 WO2001078779A2 (en) 2000-04-14 2001-04-13 Antibody alpha4beta7 integrin and its use to treat inflammatory bowel disease

Related Child Applications (1)

Application Number Title Priority Date Filing Date
JP2012105379A Division JP5764524B2 (ja) 2000-04-14 2012-05-02 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用

Publications (2)

Publication Number Publication Date
JP2003531129A JP2003531129A (ja) 2003-10-21
JP2003531129A5 true JP2003531129A5 (https=) 2011-02-17

Family

ID=27069332

Family Applications (3)

Application Number Title Priority Date Filing Date
JP2001576078A Withdrawn JP2003531129A (ja) 2000-04-14 2001-04-13 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用
JP2012105379A Expired - Lifetime JP5764524B2 (ja) 2000-04-14 2012-05-02 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用
JP2015007655A Expired - Lifetime JP6021959B2 (ja) 2000-04-14 2015-01-19 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用

Family Applications After (2)

Application Number Title Priority Date Filing Date
JP2012105379A Expired - Lifetime JP5764524B2 (ja) 2000-04-14 2012-05-02 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用
JP2015007655A Expired - Lifetime JP6021959B2 (ja) 2000-04-14 2015-01-19 炎症性腸疾患を治療するための抗体α４β７インテグリンおよびその使用

Country Status (15)

Country Link
US (5) US20010046496A1 (https=)
EP (3) EP1278543B1 (https=)
JP (3) JP2003531129A (https=)
AU (1) AU2001251629A1 (https=)
BE (1) BE2017C009I2 (https=)
CA (1) CA2406220C (https=)
CY (3) CY1113489T1 (https=)
DK (2) DK2298348T3 (https=)
ES (2) ES2398096T3 (https=)
FR (1) FR14C0080I2 (https=)
LU (1) LUC00014I2 (https=)
MX (1) MXPA02010059A (https=)
NL (1) NL300702I1 (https=)
PT (1) PT2298348T (https=)
WO (1) WO2001078779A2 (https=)

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US8030025B2 (en) 2008-02-20 2011-10-04 Amgen Inc. Antibodies directed to angiopoietin-1 and angiopoietin-2 and uses thereof

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CN103382222B (zh) * 2009-03-20 2016-12-28 安姆根有限公司 α-4-β-7异二聚体特异性拮抗剂抗体
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DK3311834T3 (da) * 2011-05-02 2026-04-20 Millennium Pharmaceuticals Inc Formulering til anti-alfa4beta7-antistof
UA116189C2 (uk) 2011-05-02 2018-02-26 Мілленніум Фармасьютікалз, Інк. КОМПОЗИЦІЯ АНТИ-α4β7 АНТИТІЛА
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
RU2648950C2 (ru) 2011-10-03 2018-04-02 Модерна Терапьютикс, Инк. Модифицированные нуклеозиды, нуклеотиды и нуклеиновые кислоты и их применение
WO2013078375A2 (en) * 2011-11-23 2013-05-30 Amgen Inc. Administration of alpha4beta7 hetero-dimer-specific antibody
CN104114572A (zh) 2011-12-16 2014-10-22 现代治疗公司 经修饰的核苷、核苷酸和核酸组合物
EA201992881A3 (ru) * 2012-01-12 2020-12-30 Милленниум Фармасьютикалз, Инк. Композиция анти-47 антитела
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
US9254311B2 (en) 2012-04-02 2016-02-09 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins
WO2014081507A1 (en) 2012-11-26 2014-05-30 Moderna Therapeutics, Inc. Terminally modified rna
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
US10023626B2 (en) 2013-09-30 2018-07-17 Modernatx, Inc. Polynucleotides encoding immune modulating polypeptides
JP2016538829A (ja) 2013-10-03 2016-12-15 モデルナ セラピューティクス インコーポレイテッドＭｏｄｅｒｎａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． 低密度リポタンパク質受容体をコードするポリヌクレオチド
WO2016086147A1 (en) 2014-11-26 2016-06-02 Millennium Pharmaceuticals, Inc. Vedolizumab for the treatment of fistulizing crohn's disease
JP6904905B2 (ja) 2014-12-24 2021-07-21 ミレニアム ファーマシューティカルズ， インコーポレイテッドＭｉｌｌｅｎｎｉｕｍ Ｐｈａｒｍａｃｅｕｔｉｃａｌｓ， Ｉｎｃ． 抗α４β７インテグリン抗体による治療の結果の予測
IL261750B2 (en) 2016-03-14 2024-07-01 Millennium Pharm Inc Method of preventing graft versus host disease
BR112018068625A2 (pt) 2016-03-14 2019-07-30 Millennium Pharm Inc métodos de tratamento ou prevenção de doença de enxerto contra hospedeiro
WO2017165742A1 (en) 2016-03-24 2017-09-28 Millennium Pharmaceuticals, Inc. Methods of treating gastrointestinal immune-related adverse events in anti-ctla4 anti-pd-1 combination treatments
MA44483A (fr) 2016-03-24 2019-01-30 Millennium Pharm Inc Procédés pour traiter des événements indésirables gastro-intestinaux d'origine immunitaire dans des traitements oncologiques immunitaires
JP7162533B2 (ja) 2016-05-04 2022-10-28 ミレニアム ファーマシューティカルズ， インコーポレイテッド 炎症性腸疾患の治療を目的とする三剤併用療法
CN109414502A (zh) 2016-06-12 2019-03-01 千禧制药公司 治疗炎症性肠病的方法
CN111032694B (zh) 2017-07-14 2024-03-08 辉瑞大药厂 针对madcam的抗体
US12492245B2 (en) * 2021-09-21 2025-12-09 University Of South Carolina Anti-CCL8 antibodies and treatment of lung injury by CCL8 inhibition
WO2024249568A1 (en) 2023-05-30 2024-12-05 Paragon Therapeutics, Inc. Alpha4beta7 integrin antibody compositions and methods of use
WO2024252368A2 (en) 2023-06-09 2024-12-12 Takeda Pharmaceutical Company Limited Methods and compositions for treating ulcerative colitis
CN121889424A (zh) 2023-08-14 2026-04-17 派拉冈医疗公司 α4β7整联蛋白结合蛋白及使用方法
WO2025149974A1 (en) 2024-01-11 2025-07-17 Takeda Pharmaceutical Company Limited Combination therapy with an anti-alpha4beta7 antibody
WO2025177214A1 (en) 2024-02-20 2025-08-28 Takeda Pharmaceutical Company Limited Therapeutic methods
WO2026058045A1 (en) 2024-09-12 2026-03-19 Takeda Pharmaceutical Company Limited Alpha4beta7 inhibitor and il-23 inhibitor combination therapy

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8030025B2 (en) 2008-02-20 2011-10-04 Amgen Inc. Antibodies directed to angiopoietin-1 and angiopoietin-2 and uses thereof
US8221749B2 (en) 2008-02-20 2012-07-17 Amgen Inc. Antibodies directed to angiopoietin-1 and angiopoietin-2 and uses thereof

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