JP2003530432A - 神経変性疾患の治療 - Google Patents
神経変性疾患の治療Info
- Publication number
- JP2003530432A JP2003530432A JP2001576010A JP2001576010A JP2003530432A JP 2003530432 A JP2003530432 A JP 2003530432A JP 2001576010 A JP2001576010 A JP 2001576010A JP 2001576010 A JP2001576010 A JP 2001576010A JP 2003530432 A JP2003530432 A JP 2003530432A
- Authority
- JP
- Japan
- Prior art keywords
- kit
- disease
- group
- treatment
- ring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
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- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/06—Antianaemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
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- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Biomedical Technology (AREA)
- Emergency Medicine (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Molecular Biology (AREA)
- Diabetes (AREA)
- Nanotechnology (AREA)
- Hematology (AREA)
- General Physics & Mathematics (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Psychology (AREA)
- Physics & Mathematics (AREA)
- Composite Materials (AREA)
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- Obesity (AREA)
- Urology & Nephrology (AREA)
- Hospice & Palliative Care (AREA)
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Applications Claiming Priority (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US19649700P | 2000-04-12 | 2000-04-12 | |
| US60/196,497 | 2000-04-12 | ||
| US21422100P | 2000-06-23 | 2000-06-23 | |
| US60/214,221 | 2000-06-23 | ||
| US24889000P | 2000-11-15 | 2000-11-15 | |
| US60/248,890 | 2000-11-15 | ||
| PCT/US2001/012484 WO2001078709A2 (en) | 2000-04-12 | 2001-04-12 | Treatment of neurodegenerative disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003530432A true JP2003530432A (ja) | 2003-10-14 |
| JP2003530432A5 JP2003530432A5 (https=) | 2008-06-05 |
Family
ID=27393612
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001576010A Pending JP2003530432A (ja) | 2000-04-12 | 2001-04-12 | 神経変性疾患の治療 |
Country Status (6)
| Country | Link |
|---|---|
| US (1) | US20030060487A1 (https=) |
| EP (1) | EP1328261A2 (https=) |
| JP (1) | JP2003530432A (https=) |
| AU (1) | AU2001253597A1 (https=) |
| CA (1) | CA2404858A1 (https=) |
| WO (1) | WO2001078709A2 (https=) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013051266A1 (ja) * | 2011-10-03 | 2013-04-11 | 独立行政法人国立長寿医療研究センター | タウ凝集阻害剤 |
| US9907799B2 (en) | 2013-04-02 | 2018-03-06 | The Doshisha | Tau aggregation inhibitor |
| JP2019521964A (ja) * | 2016-05-13 | 2019-08-08 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | アドレナリン受容体調節化合物およびその使用方法 |
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| JP4585170B2 (ja) | 2000-10-03 | 2010-11-24 | ミナーヴァ・バイオテクノロジーズ・コーポレーション | 流動の中断に基づく相互作用の電子検出および相互作用の検出 |
| US7054758B2 (en) | 2001-01-30 | 2006-05-30 | Sciona Limited | Computer-assisted means for assessing lifestyle risk factors |
| WO2003013437A2 (en) * | 2001-08-07 | 2003-02-20 | University Of Delaware | Compositions and methods for the prevention and treatment of huntington's disease |
| US20040096880A1 (en) * | 2001-08-07 | 2004-05-20 | Kmiec Eric B. | Compositions and methods for the treatment of diseases exhibiting protein misassembly and aggregation |
| FR2828693B1 (fr) † | 2001-08-14 | 2004-06-18 | Exonhit Therapeutics Sa | Nouvelle cible moleculaire de la neurotoxicite |
| EP2329822A1 (en) | 2001-09-05 | 2011-06-08 | Minerva Biotechnologies Corporation | Compositions and methods of treatment of cancer |
| US20060280730A1 (en) * | 2001-10-12 | 2006-12-14 | Cedars-Sinai Medical Center | Induction of apoptosis of malignant cells by activation of calcium-activated potassium channels |
| JP2006517674A (ja) | 2002-12-20 | 2006-07-27 | ミネルバ バイオテクノロジーズ コーポレーション | ナノ粒子を含む光学デバイスおよび方法 |
| ES2272911T3 (es) * | 2003-04-25 | 2007-05-01 | Neurofit Sas | Uso de derivados de fenotiazina piperazina en la fabricacion de un medicamento con efectos neuroprotector y/o neurotroficos sobre cns y/o pns. |
| FR2856595B1 (fr) * | 2003-06-27 | 2008-05-30 | Exonhit Therapeutics Sa | Methodes et compositions pour le traitement de deficits cognitifs. |
| US20050059744A1 (en) * | 2003-09-12 | 2005-03-17 | Allergan, Inc. | Methods and compositions for the treatment of pain and other alpha 2 adrenergic-mediated conditions |
| CA2628074C (en) | 2005-10-25 | 2014-01-14 | Shionogi & Co., Ltd. | Aminodihydrothiazine derivative |
| US8178509B2 (en) * | 2006-02-10 | 2012-05-15 | University Of Virginia Patent Foundation | Method to treat sickle cell disease |
| AU2007218217A1 (en) * | 2006-02-24 | 2007-08-30 | Axelar Ab | Use of cyclolignans for the treatment of type 2 diabetes and as contraceptives |
| JP5383484B2 (ja) | 2007-04-24 | 2014-01-08 | 塩野義製薬株式会社 | 環式基で置換されたアミノジヒドロチアジン誘導体 |
| US8653067B2 (en) | 2007-04-24 | 2014-02-18 | Shionogi & Co., Ltd. | Pharmaceutical composition for treating Alzheimer's disease |
| WO2009005469A2 (en) * | 2007-07-03 | 2009-01-08 | David Erlinge | The use of compounds such as pyridoxal derivatives for the treatment of diabetes or diseases associated with the metabolic syndrome |
| WO2013148740A1 (en) * | 2012-03-26 | 2013-10-03 | The Trustees Of Columbia University In The City Of New York | 4–aminopyridine as a therapeutic agent for spinal muscular atrophy |
| KR101324426B1 (ko) | 2008-06-13 | 2013-10-31 | 시오노기세야쿠 가부시키가이샤 | β 세크레타제 저해 작용을 갖는 황 함유 복소환 유도체 |
| CN102186841A (zh) | 2008-10-22 | 2011-09-14 | 盐野义制药株式会社 | 具有bace1抑制活性的2-氨基嘧啶-4-酮及2-氨基吡啶衍生物 |
| MX2012006491A (es) | 2009-12-11 | 2012-07-03 | Shionogi & Co | Derivados de oxazina. |
| US9662347B2 (en) * | 2010-05-11 | 2017-05-30 | Gachon University Of Industry-Academic Cooperation Foundation | Method for inhibiting the induction of cell death by inhibiting the synthesis or secretion of age-albumin in cells of the mononuclear phagocyte system |
| US20120101167A1 (en) * | 2010-10-25 | 2012-04-26 | Langham Maurice E | Treatment of ocular and cerebral ischemia |
| JP5816630B2 (ja) | 2010-10-29 | 2015-11-18 | 塩野義製薬株式会社 | ナフチリジン誘導体 |
| EP2634188A4 (en) | 2010-10-29 | 2014-05-07 | Shionogi & Co | FUSIONED AMINODIHYDROPYRIMIDINE DERIVATIVE |
| US8883779B2 (en) | 2011-04-26 | 2014-11-11 | Shinogi & Co., Ltd. | Oxazine derivatives and a pharmaceutical composition for inhibiting BACE1 containing them |
| CN102381991A (zh) * | 2011-10-22 | 2012-03-21 | 杭州福斯特药业有限公司 | 一种章胺盐酸盐的合成方法 |
| EP2912035A4 (en) | 2012-10-24 | 2016-06-15 | Shionogi & Co | DERIVATIVES OF DIHYDROOXAZINE OR OXAZEPINE HAVING BACE1 INHIBITING ACTIVITY |
| US20160154928A1 (en) * | 2013-07-12 | 2016-06-02 | Immuneering Corporation | Systems, methods, and environment for automated review of genomic data to identify downregulated and/or upregulated gene expression indicative of a disease or condition |
| US11648212B2 (en) * | 2016-02-03 | 2023-05-16 | Intelgenx Corp. | Loxapine film oral dosage form |
| WO2022087460A1 (en) * | 2020-10-22 | 2022-04-28 | Icahn School Of Medicine At Mount Sinai | Methods for identifying and targeting the molecular subtypes of alzheimer's disease |
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| US5962463A (en) * | 1992-10-09 | 1999-10-05 | Massachusetts Institute Of Technology | Methods of stimulating non-amyloidogenic processing of the amyloid precursor protein |
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| US5605911A (en) * | 1995-01-31 | 1997-02-25 | Washington University | Use of alpha-2 adrenergic drugs to prevent adverse effects of NMDA receptor hypofunction (NRH) |
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-
2001
- 2001-04-12 US US09/835,099 patent/US20030060487A1/en not_active Abandoned
- 2001-04-12 JP JP2001576010A patent/JP2003530432A/ja active Pending
- 2001-04-12 AU AU2001253597A patent/AU2001253597A1/en not_active Abandoned
- 2001-04-12 CA CA002404858A patent/CA2404858A1/en not_active Abandoned
- 2001-04-12 WO PCT/US2001/012484 patent/WO2001078709A2/en not_active Ceased
- 2001-04-12 EP EP01927116A patent/EP1328261A2/en not_active Withdrawn
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2013051266A1 (ja) * | 2011-10-03 | 2013-04-11 | 独立行政法人国立長寿医療研究センター | タウ凝集阻害剤 |
| JPWO2013051266A1 (ja) * | 2011-10-03 | 2015-03-30 | 独立行政法人国立長寿医療研究センター | タウ凝集阻害剤 |
| JP2017119722A (ja) * | 2011-10-03 | 2017-07-06 | 国立研究開発法人国立長寿医療研究センター | タウ凝集阻害剤 |
| US9907799B2 (en) | 2013-04-02 | 2018-03-06 | The Doshisha | Tau aggregation inhibitor |
| JP2019521964A (ja) * | 2016-05-13 | 2019-08-08 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | アドレナリン受容体調節化合物およびその使用方法 |
Also Published As
| Publication number | Publication date |
|---|---|
| AU2001253597A1 (en) | 2001-10-30 |
| CA2404858A1 (en) | 2001-10-25 |
| US20030060487A1 (en) | 2003-03-27 |
| EP1328261A2 (en) | 2003-07-23 |
| WO2001078709A3 (en) | 2003-04-17 |
| WO2001078709A2 (en) | 2001-10-25 |
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