JP2003528637A - 還流インキュベータ装置とその井戸組立体 - Google Patents
還流インキュベータ装置とその井戸組立体Info
- Publication number
- JP2003528637A JP2003528637A JP2001571869A JP2001571869A JP2003528637A JP 2003528637 A JP2003528637 A JP 2003528637A JP 2001571869 A JP2001571869 A JP 2001571869A JP 2001571869 A JP2001571869 A JP 2001571869A JP 2003528637 A JP2003528637 A JP 2003528637A
- Authority
- JP
- Japan
- Prior art keywords
- fluid
- well
- assembly
- inlet
- lid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 238000010992 reflux Methods 0.000 title claims abstract description 14
- 239000012530 fluid Substances 0.000 claims abstract description 98
- 230000002572 peristaltic effect Effects 0.000 claims abstract description 17
- 238000010438 heat treatment Methods 0.000 claims abstract description 14
- 239000012780 transparent material Substances 0.000 claims description 6
- 238000012258 culturing Methods 0.000 claims description 4
- 238000000034 method Methods 0.000 claims description 4
- 230000015572 biosynthetic process Effects 0.000 claims description 2
- 241000255777 Lepidoptera Species 0.000 claims 1
- 238000007789 sealing Methods 0.000 claims 1
- 230000008602 contraction Effects 0.000 abstract 1
- 210000003754 fetus Anatomy 0.000 description 15
- 210000001161 mammalian embryo Anatomy 0.000 description 15
- 239000007789 gas Substances 0.000 description 12
- 239000002609 medium Substances 0.000 description 9
- 239000001963 growth medium Substances 0.000 description 6
- 230000001605 fetal effect Effects 0.000 description 5
- 239000003102 growth factor Substances 0.000 description 4
- 230000033001 locomotion Effects 0.000 description 4
- 238000012360 testing method Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 3
- 235000015097 nutrients Nutrition 0.000 description 3
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 description 2
- CURLTUGMZLYLDI-UHFFFAOYSA-N Carbon dioxide Chemical compound O=C=O CURLTUGMZLYLDI-UHFFFAOYSA-N 0.000 description 2
- 208000009701 Embryo Loss Diseases 0.000 description 2
- 208000001951 Fetal Death Diseases 0.000 description 2
- 206010055690 Foetal death Diseases 0.000 description 2
- 230000007773 growth pattern Effects 0.000 description 2
- 239000007788 liquid Substances 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 238000002054 transplantation Methods 0.000 description 2
- 239000002699 waste material Substances 0.000 description 2
- 241000124008 Mammalia Species 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 230000002528 anti-freeze Effects 0.000 description 1
- VLYDPWNOCPZGEV-UHFFFAOYSA-M benzyl-dimethyl-[2-[2-[2-methyl-4-(2,4,4-trimethylpentan-2-yl)phenoxy]ethoxy]ethyl]azanium;chloride;hydrate Chemical compound O.[Cl-].CC1=CC(C(C)(C)CC(C)(C)C)=CC=C1OCCOCC[N+](C)(C)CC1=CC=CC=C1 VLYDPWNOCPZGEV-UHFFFAOYSA-M 0.000 description 1
- 229910002092 carbon dioxide Inorganic materials 0.000 description 1
- 239000001569 carbon dioxide Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 239000012531 culture fluid Substances 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 238000009792 diffusion process Methods 0.000 description 1
- 210000002257 embryonic structure Anatomy 0.000 description 1
- 230000002349 favourable effect Effects 0.000 description 1
- 239000011521 glass Substances 0.000 description 1
- 230000012010 growth Effects 0.000 description 1
- 238000000338 in vitro Methods 0.000 description 1
- 238000011065 in-situ storage Methods 0.000 description 1
- YFONKFDEZLYQDH-BOURZNODSA-N indaziflam Chemical compound CC(F)C1=NC(N)=NC(N[C@H]2C3=CC(C)=CC=C3C[C@@H]2C)=N1 YFONKFDEZLYQDH-BOURZNODSA-N 0.000 description 1
- 238000009434 installation Methods 0.000 description 1
- 238000012423 maintenance Methods 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 229910052757 nitrogen Inorganic materials 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 239000004033 plastic Substances 0.000 description 1
- 239000004417 polycarbonate Substances 0.000 description 1
- 229920000515 polycarbonate Polymers 0.000 description 1
- 230000005855 radiation Effects 0.000 description 1
- 239000007320 rich medium Substances 0.000 description 1
- 238000003860 storage Methods 0.000 description 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M3/00—Tissue, human, animal or plant cell, or virus culture apparatus
- C12M3/02—Tissue, human, animal or plant cell, or virus culture apparatus with means providing suspensions
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M21/00—Bioreactors or fermenters specially adapted for specific uses
- C12M21/06—Bioreactors or fermenters specially adapted for specific uses for in vitro fertilization
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/02—Form or structure of the vessel
- C12M23/12—Well or multiwell plates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M23/00—Constructional details, e.g. recesses, hinges
- C12M23/22—Transparent or translucent parts
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M29/00—Means for introduction, extraction or recirculation of materials, e.g. pumps
- C12M29/10—Perfusion
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
- C12M41/00—Means for regulation, monitoring, measurement or control, e.g. flow regulation
- C12M41/12—Means for regulation, monitoring, measurement or control, e.g. flow regulation of temperature
- C12M41/14—Incubators; Climatic chambers
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- Biomedical Technology (AREA)
- Biochemistry (AREA)
- Sustainable Development (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Clinical Laboratory Science (AREA)
- Physics & Mathematics (AREA)
- Thermal Sciences (AREA)
- Analytical Chemistry (AREA)
- Molecular Biology (AREA)
- Cell Biology (AREA)
- Virology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| AUPQ6530A AUPQ653000A0 (en) | 2000-03-28 | 2000-03-28 | Perfusion incubator |
| AU6530 | 2000-03-28 | ||
| PCT/US2001/009972 WO2001072954A2 (en) | 2000-03-28 | 2001-03-28 | Perfusion incubator |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003528637A true JP2003528637A (ja) | 2003-09-30 |
| JP2003528637A5 JP2003528637A5 (enExample) | 2008-05-15 |
Family
ID=3820627
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001571869A Pending JP2003528637A (ja) | 2000-03-28 | 2001-03-28 | 還流インキュベータ装置とその井戸組立体 |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US6627435B2 (enExample) |
| EP (1) | EP1268742B1 (enExample) |
| JP (1) | JP2003528637A (enExample) |
| KR (1) | KR20030001391A (enExample) |
| AT (1) | ATE412732T1 (enExample) |
| AU (1) | AUPQ653000A0 (enExample) |
| CA (1) | CA2400164C (enExample) |
| DE (1) | DE60136342D1 (enExample) |
| WO (1) | WO2001072954A2 (enExample) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20040132174A1 (en) * | 2000-03-28 | 2004-07-08 | Smith Allan Joseph Hilling | Perfusion incubator |
| JP4230176B2 (ja) * | 2002-06-28 | 2009-02-25 | 独立行政法人科学技術振興機構 | 胚の培養装置及び胚の左右非対称性を制御する方法 |
| DK1539921T3 (da) * | 2002-09-16 | 2008-04-14 | Pan Biotech Gmbh | Indretning til dyrkning af celler, især celler fra mennesker eller dyr |
| ES2295465T3 (es) * | 2002-09-16 | 2008-04-16 | Pan-Biotech Gmbh | Procedimiento para el cultivo de celulas, en especial de celulas humanas o de animales. |
| WO2004027016A1 (en) * | 2002-09-17 | 2004-04-01 | Cook Urological, Incorporated | Improved perfusion incubator |
| US7276351B2 (en) | 2003-09-10 | 2007-10-02 | Seahorse Bioscience | Method and device for measuring multiple physiological properties of cells |
| US8658349B2 (en) | 2006-07-13 | 2014-02-25 | Seahorse Bioscience | Cell analysis apparatus and method |
| WO2006124672A2 (en) * | 2005-05-12 | 2006-11-23 | University Of Alabama In Huntsville | Apparatus and method for incubating cell cultures |
| US10174280B2 (en) * | 2012-04-06 | 2019-01-08 | Corsolutions Llc | Apparatus, system, and method providing fluid flow for cell growth |
| EP2920292B1 (en) | 2012-11-13 | 2017-01-11 | Agilent Technologies, Inc. | Apparatus and methods for three-dimensional tissue measurements based on controlled media flow |
| EP3689467B1 (en) | 2014-06-02 | 2025-04-09 | Agilent Technologies, Inc. | Microplate carrier for analysis of biological samples |
| WO2018230968A1 (ko) * | 2017-06-14 | 2018-12-20 | 계명대학교 산학협력단 | 모세관 배양장치 |
| KR102313128B1 (ko) | 2019-11-25 | 2021-10-15 | 한국생산기술연구원 | 액체 제거가 가능한 연속식 세포 배양 장치 |
Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0350896Y2 (enExample) * | 1986-05-23 | 1991-10-30 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3426444A (en) * | 1967-08-09 | 1969-02-11 | Us Army | Laboratory aerosol device |
| AT345224B (de) | 1976-07-15 | 1978-09-11 | Chemap Ag | Verfahren und vorrichtung zum kultivieren von tierischen und humanen gewebezellen |
| SE448881B (sv) | 1981-03-12 | 1987-03-23 | Erik Walum | Apparat for genomforandet av perfusionsodling av en eller flera cellkulturer samt forfarande for perfusionsodling av en eller flera cellkulturer |
| US4435508A (en) * | 1981-11-20 | 1984-03-06 | Gabridge Michael G | Tissue culture vessel |
| US4734372A (en) * | 1983-02-04 | 1988-03-29 | Brown University Research Foundation | Cell culturing methods and apparatus |
| WO1984003709A1 (fr) | 1983-03-16 | 1984-09-27 | Zent Finanz & Kommerz Ag | Procede et installation pour cultiver des micro-organismes dans une solution de substrat de culture |
| US4814278A (en) | 1985-02-05 | 1989-03-21 | Teijin Limited | Culture apparatus and method |
| DE3612453A1 (de) | 1986-04-14 | 1987-10-15 | Diessel Gmbh & Co | Vorrichtung zur kultivierung von zellkulturen |
| EP0394406B1 (en) * | 1988-10-21 | 1995-04-26 | Molecular Devices Corporation | Methods and apparatus for detecting the effect of cell affecting agents on living cells |
| US5139951A (en) | 1990-10-10 | 1992-08-18 | Costar Corporation | Culture device having a detachable cell or tissue growth surface |
| US5443985A (en) | 1993-07-22 | 1995-08-22 | Alberta Research Council | Cell culture bioreactor |
| JP3707303B2 (ja) * | 1999-06-30 | 2005-10-19 | 株式会社日立製作所 | ヒスタミン計測方法およびヒスタミン計測装置 |
-
2000
- 2000-03-28 AU AUPQ6530A patent/AUPQ653000A0/en not_active Abandoned
-
2001
- 2001-03-28 JP JP2001571869A patent/JP2003528637A/ja active Pending
- 2001-03-28 AT AT01922798T patent/ATE412732T1/de not_active IP Right Cessation
- 2001-03-28 EP EP01922798A patent/EP1268742B1/en not_active Expired - Lifetime
- 2001-03-28 DE DE60136342T patent/DE60136342D1/de not_active Expired - Fee Related
- 2001-03-28 CA CA002400164A patent/CA2400164C/en not_active Expired - Fee Related
- 2001-03-28 KR KR1020027012772A patent/KR20030001391A/ko not_active Withdrawn
- 2001-03-28 WO PCT/US2001/009972 patent/WO2001072954A2/en not_active Ceased
- 2001-03-28 US US09/819,407 patent/US6627435B2/en not_active Expired - Fee Related
Patent Citations (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPH0350896Y2 (enExample) * | 1986-05-23 | 1991-10-30 |
Also Published As
| Publication number | Publication date |
|---|---|
| US6627435B2 (en) | 2003-09-30 |
| CA2400164C (en) | 2009-10-20 |
| DE60136342D1 (de) | 2008-12-11 |
| WO2001072954A2 (en) | 2001-10-04 |
| EP1268742A2 (en) | 2003-01-02 |
| AUPQ653000A0 (en) | 2000-04-20 |
| CA2400164A1 (en) | 2001-10-04 |
| US20010039045A1 (en) | 2001-11-08 |
| ATE412732T1 (de) | 2008-11-15 |
| EP1268742B1 (en) | 2008-10-29 |
| WO2001072954A3 (en) | 2002-07-04 |
| KR20030001391A (ko) | 2003-01-06 |
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