JP2003525251A5 - - Google Patents
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- Publication number
- JP2003525251A5 JP2003525251A5 JP2001563137A JP2001563137A JP2003525251A5 JP 2003525251 A5 JP2003525251 A5 JP 2003525251A5 JP 2001563137 A JP2001563137 A JP 2001563137A JP 2001563137 A JP2001563137 A JP 2001563137A JP 2003525251 A5 JP2003525251 A5 JP 2003525251A5
- Authority
- JP
- Japan
- Prior art keywords
- pharmaceutical composition
- polypeptide
- zcyto7
- expression
- schwann cells
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 description 14
- 102000013691 Interleukin-17 Human genes 0.000 description 5
- 108050003558 Interleukin-17 Proteins 0.000 description 5
- 229920001184 polypeptide Polymers 0.000 description 5
- 102000004196 processed proteins & peptides Human genes 0.000 description 5
- 108090000765 processed proteins & peptides Proteins 0.000 description 5
- 208000016192 Demyelinating disease Diseases 0.000 description 4
- 210000001428 peripheral nervous system Anatomy 0.000 description 4
- 102000006386 Myelin Proteins Human genes 0.000 description 2
- 108010083674 Myelin Proteins Proteins 0.000 description 2
- 230000003210 demyelinating effect Effects 0.000 description 2
- 210000005012 myelin Anatomy 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 210000004116 schwann cell Anatomy 0.000 description 2
- KISWVXRQTGLFGD-UHFFFAOYSA-N 2-[[2-[[6-amino-2-[[2-[[2-[[5-amino-2-[[2-[[1-[2-[[6-amino-2-[(2,5-diamino-5-oxopentanoyl)amino]hexanoyl]amino]-5-(diaminomethylideneamino)pentanoyl]pyrrolidine-2-carbonyl]amino]-3-hydroxypropanoyl]amino]-5-oxopentanoyl]amino]-5-(diaminomethylideneamino)p Chemical compound C1CCN(C(=O)C(CCCN=C(N)N)NC(=O)C(CCCCN)NC(=O)C(N)CCC(N)=O)C1C(=O)NC(CO)C(=O)NC(CCC(N)=O)C(=O)NC(CCCN=C(N)N)C(=O)NC(CO)C(=O)NC(CCCCN)C(=O)NC(C(=O)NC(CC(C)C)C(O)=O)CC1=CC=C(O)C=C1 KISWVXRQTGLFGD-UHFFFAOYSA-N 0.000 description 1
- 208000032131 Diabetic Neuropathies Diseases 0.000 description 1
- 208000035895 Guillain-Barré syndrome Diseases 0.000 description 1
- 206010061598 Immunodeficiency Diseases 0.000 description 1
- 208000029462 Immunodeficiency disease Diseases 0.000 description 1
- 206010049567 Miller Fisher syndrome Diseases 0.000 description 1
- 102000047918 Myelin Basic Human genes 0.000 description 1
- 102000055325 Myelin P0 Human genes 0.000 description 1
- 108700021863 Myelin P0 Proteins 0.000 description 1
- 101710107068 Myelin basic protein Proteins 0.000 description 1
- 206010037779 Radiculopathy Diseases 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 230000007813 immunodeficiency Effects 0.000 description 1
- 201000001119 neuropathy Diseases 0.000 description 1
- 230000007823 neuropathy Effects 0.000 description 1
- 208000033808 peripheral neuropathy Diseases 0.000 description 1
- 208000006473 polyradiculopathy Diseases 0.000 description 1
- 230000003612 virological effect Effects 0.000 description 1
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US51522300A | 2000-02-29 | 2000-02-29 | |
| US09/515,223 | 2000-02-29 | ||
| PCT/US2001/006294 WO2001064240A2 (en) | 2000-02-29 | 2001-02-27 | Methods for promoting production of myelin by schwann cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003525251A JP2003525251A (ja) | 2003-08-26 |
| JP2003525251A5 true JP2003525251A5 (enExample) | 2008-04-17 |
Family
ID=24050447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001563137A Pending JP2003525251A (ja) | 2000-02-29 | 2001-02-27 | シュワン細胞によるミエリンの産生を促進するための方法 |
Country Status (5)
| Country | Link |
|---|---|
| EP (1) | EP1259253A2 (enExample) |
| JP (1) | JP2003525251A (enExample) |
| AU (1) | AU2001241816A1 (enExample) |
| CA (1) | CA2401716A1 (enExample) |
| WO (1) | WO2001064240A2 (enExample) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2452233A1 (en) * | 2001-03-26 | 2002-10-03 | Zymogenetics, Inc. | Method of inducing proliferation of retinal stem cells |
| EP2089050A2 (en) * | 2006-11-08 | 2009-08-19 | Zymogenetics, Inc. | Il- 17b for use in wound healing |
| CN107106606B (zh) | 2014-09-12 | 2022-06-14 | 杜雷安教育基金会行政处 | 神经微生理系统和使用其的方法 |
| JP7186094B2 (ja) | 2016-05-06 | 2022-12-08 | イグジキュア オペレーティング カンパニー | インターロイキン１７受容体ｍＲＮＡの特異的ノックダウンのためのアンチセンスオリゴヌクレオチド（ＡＳＯ）を提示するリポソーム系球状核酸（ＳＮＡ）構築物 |
| US11696954B2 (en) | 2017-04-28 | 2023-07-11 | Exicure Operating Company | Synthesis of spherical nucleic acids using lipophilic moieties |
| CN120392966B (zh) * | 2025-07-01 | 2025-10-21 | 华中科技大学同济医学院附属协和医院 | 糖尿病周围神经病变靶向治疗的药物及调控雪旺细胞增殖功能的神经保护药物 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO2000073452A2 (en) * | 1999-06-02 | 2000-12-07 | Genentech, Inc. | Compositions and methods for the treatment of immune related diseases |
| US5707829A (en) * | 1995-08-11 | 1998-01-13 | Genetics Institute, Inc. | DNA sequences and secreted proteins encoded thereby |
| EP0839196B1 (en) * | 1995-07-19 | 2005-05-11 | Genetics Institute, LLC | Human ctla-8 and uses of ctla-8-related proteins |
| EA199900869A1 (ru) * | 1997-04-25 | 2000-12-25 | Займодженетикс, Инк. | Цитокин-подобный фактор 7 млекопитающих |
| EP1012260A4 (en) * | 1997-07-16 | 2001-05-09 | Human Genome Sciences Inc | INTERLEUKINE-20 |
| EP1240325B1 (en) * | 1999-12-23 | 2009-09-30 | Genentech, Inc. | Il-17 and il-17r homologous polypeptides and therapeutic uses thereof |
-
2001
- 2001-02-27 AU AU2001241816A patent/AU2001241816A1/en not_active Abandoned
- 2001-02-27 EP EP01913120A patent/EP1259253A2/en not_active Withdrawn
- 2001-02-27 JP JP2001563137A patent/JP2003525251A/ja active Pending
- 2001-02-27 CA CA002401716A patent/CA2401716A1/en not_active Abandoned
- 2001-02-27 WO PCT/US2001/006294 patent/WO2001064240A2/en not_active Ceased