JP2003524781A - 磁性粒子用高性能磁気センサ - Google Patents

磁性粒子用高性能磁気センサ

Info

Publication number
JP2003524781A
JP2003524781A JP2001556304A JP2001556304A JP2003524781A JP 2003524781 A JP2003524781 A JP 2003524781A JP 2001556304 A JP2001556304 A JP 2001556304A JP 2001556304 A JP2001556304 A JP 2001556304A JP 2003524781 A JP2003524781 A JP 2003524781A
Authority
JP
Japan
Prior art keywords
magnetic
conductive
layer
ferromagnetic material
plane
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001556304A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003524781A5 (enExample
Inventor
プリンツ、ゲイリー、エー.
ミラー、マイケル、エム.
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Government of the United States of America
Original Assignee
Government of the United States of America
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Government of the United States of America filed Critical Government of the United States of America
Publication of JP2003524781A publication Critical patent/JP2003524781A/ja
Publication of JP2003524781A5 publication Critical patent/JP2003524781A5/ja
Pending legal-status Critical Current

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/76—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids by investigating susceptibility
    • G—PHYSICS
    • G11—INFORMATION STORAGE
    • G11C—STATIC STORES
    • G11C11/00—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor
    • G11C11/02—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements
    • G11C11/14—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements using thin-film elements
    • G11C11/15—Digital stores characterised by the use of particular electric or magnetic storage elements; Storage elements therefor using magnetic elements using thin-film elements using multiple magnetic layers
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N27/00—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means
    • G01N27/72—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables
    • G01N27/74—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids
    • G01N27/745—Investigating or analysing materials by the use of electric, electrochemical, or magnetic means by investigating magnetic variables of fluids for detecting magnetic beads used in biochemical assays
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54313—Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals the carrier being characterised by its particulate form
    • G01N33/54326—Magnetic particles

Landscapes

  • Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Hematology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Electrochemistry (AREA)
  • Cell Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Food Science & Technology (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Computer Hardware Design (AREA)
  • Investigating Or Analyzing Materials By The Use Of Magnetic Means (AREA)
  • Measuring Magnetic Variables (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
JP2001556304A 2000-02-04 2000-08-17 磁性粒子用高性能磁気センサ Pending JP2003524781A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/497,754 US6468809B1 (en) 2000-02-04 2000-02-04 High efficiency magnetic sensor for magnetic particles
US09/497,754 2000-02-04
PCT/US2000/020782 WO2001057506A1 (en) 2000-02-04 2000-08-17 High efficiency magnetic sensor for magnetic particles

Publications (2)

Publication Number Publication Date
JP2003524781A true JP2003524781A (ja) 2003-08-19
JP2003524781A5 JP2003524781A5 (enExample) 2008-07-31

Family

ID=23978168

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001556304A Pending JP2003524781A (ja) 2000-02-04 2000-08-17 磁性粒子用高性能磁気センサ

Country Status (6)

Country Link
US (3) US6468809B1 (enExample)
EP (1) EP1299714A4 (enExample)
JP (1) JP2003524781A (enExample)
KR (1) KR100651700B1 (enExample)
AU (1) AU2000267514A1 (enExample)
WO (1) WO2001057506A1 (enExample)

Cited By (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004117822A (ja) * 2002-09-26 2004-04-15 Toppan Forms Co Ltd 感熱発色性液体トナー受容層形成用塗工液およびそれを用いた感熱発色性静電印刷用シート
JP2007514932A (ja) * 2003-11-12 2007-06-07 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 磁性ナノ粒子、磁性検出器アレイ、および生物学的分子の検出におけるそれらの使用方法
JP2007538252A (ja) * 2004-05-18 2007-12-27 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 生体検知において信号対バックグランド比を向上する磁気的な回転
JP2008522150A (ja) * 2004-11-30 2008-06-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ バイオセンサにおける磁気クロストークを低減する手段及び方法
JP2009002838A (ja) * 2007-06-22 2009-01-08 Canon Inc 検出装置及び検出方法
JP2009115590A (ja) * 2007-11-06 2009-05-28 Tokyo Institute Of Technology バイオセンサ用マーカ、バイオセンサ、及びバイオセンサ用マーカ検出方法
JP2011512517A (ja) * 2008-01-18 2011-04-21 マグアイシー テクノロジーズ インコーポレイテッド アドレス可能な磁気トンネル接合アレイを用いて磁性粒子を検出する装置
JP2014528071A (ja) * 2011-09-14 2014-10-23 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 外部磁界を必要としない磁気生体センサ
US9823316B2 (en) 2011-10-19 2017-11-21 Regents Of The University Of Minnesota Magnetic biomedical sensors and sensing system for high-throughput biomolecule testing

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6468809B1 (en) * 2000-02-04 2002-10-22 The United States Of America As Represented By The Secretary Of The Navy High efficiency magnetic sensor for magnetic particles
WO2002016904A2 (en) * 2000-08-23 2002-02-28 Imego Ab Microfluidic device and method with transport of magnetic particles into and out of wells
NO20014746D0 (no) * 2001-09-28 2001-09-28 Clas M Kjoelberg Smertelindrende middel
US7329392B2 (en) * 2001-10-19 2008-02-12 Sri International Device and method for handling reaction components
SE0103859D0 (sv) * 2001-11-20 2001-11-20 Sven Oscarsson Novel artificial structures with magnetic functionality
US6552554B1 (en) * 2001-12-06 2003-04-22 The United States Of America As Represented By The Secretary Of The Navy Testing current perpendicular to plane giant magnetoresistance multilayer devices
KR20040068968A (ko) * 2001-12-21 2004-08-02 코닌클리케 필립스 일렉트로닉스 엔.브이. 마이크로-어레이상의 자기 나노입자들의 면적 밀도를측정하는 센서 및 방법
US7126331B2 (en) 2002-07-29 2006-10-24 The United States Of America As Represented By The Secretary Of The Navy Integrated gradiometer
US7183120B2 (en) * 2002-10-31 2007-02-27 Honeywell International Inc. Etch-stop material for improved manufacture of magnetic devices
JP4399211B2 (ja) 2002-12-21 2010-01-13 株式会社ハイニックスセミコンダクター バイオセンサー
JP2005315678A (ja) * 2004-04-28 2005-11-10 Canon Inc 検出方法、検出デバイス及び検出用キット
JP4756868B2 (ja) * 2005-01-31 2011-08-24 キヤノン株式会社 検出方法
US7304360B2 (en) 2005-07-12 2007-12-04 Magic Technologies, Inc. Method of forming super-paramagnetic cladding material on conductive lines of MRAM devices
US7696548B2 (en) 2005-08-09 2010-04-13 Magic Technologies, Inc. MRAM with super-paramagnetic sensing layer
US8512559B2 (en) * 2005-11-18 2013-08-20 Intel Corporation Device, method, and system for separation and detection of biomolecules and cells
DE102006016334B4 (de) * 2006-04-06 2018-11-15 Boehringer Ingelheim Vetmedica Gmbh Verfahren und Vorrichtung zur Detektion magnetisierbarer Partikel
US8133439B2 (en) 2006-08-01 2012-03-13 Magic Technologies, Inc. GMR biosensor with enhanced sensitivity
US9863939B2 (en) 2007-09-20 2018-01-09 Magarray, Inc. Analyte detection with magnetic sensors
CN101802614B (zh) * 2007-09-21 2013-08-07 皇家飞利浦电子股份有限公司 具有高频交流磁场的传感器及描述流体样本特征的方法
US20100277160A1 (en) * 2007-12-18 2010-11-04 Koninklijke Philips Electronics N.V. Magnetic sensor device
US8053244B2 (en) * 2008-08-13 2011-11-08 Seagate Technology Llc Magnetic oscillator based biosensor
EP2401625B1 (en) 2009-02-26 2014-01-22 Regents of the University of Minnesota High magnetic moment particle detection
US8334147B2 (en) * 2009-05-26 2012-12-18 Magic Technologies, Inc. Bio-sensor with hard-direction field
US8444920B2 (en) * 2009-09-16 2013-05-21 Weiqun Liu O-ring systems and methods for quantification of multiplex biomarkers in multiple samples
KR101093776B1 (ko) 2010-01-21 2011-12-19 충남대학교산학협력단 자기 센서
KR101157997B1 (ko) * 2010-08-19 2012-06-25 주식회사 엘지생명과학 자기저항센서를 이용한 검출시스템
US20140099663A1 (en) * 2010-11-15 2014-04-10 Regents Of The University Of Minnesota Gmr sensor
EP2684036B1 (en) 2011-03-09 2018-04-25 Magarray, Inc. Systems and methods for high-throughput detection of an analyte in a sample
US10739337B2 (en) 2011-08-30 2020-08-11 Board Of Trustees Of Michigan State University Extraction and detection of pathogens using carbohydrate-functionalized biosensors
DE112012005566T8 (de) * 2012-01-04 2014-11-13 National Institute For Materials Science Seltenerdnanoverbundmagnet
US20140167786A1 (en) * 2012-12-14 2014-06-19 Schneider Electric USA, Inc. Current Sensor For Power Measurement Applications
JP6422935B2 (ja) 2013-03-15 2018-11-14 マグアレイ,インコーポレイテッド 磁気トンネル接合センサ及びその使用方法
US10145906B2 (en) 2015-12-17 2018-12-04 Analog Devices Global Devices, systems and methods including magnetic structures
PT110107B (pt) 2017-05-26 2021-11-16 Univ Aveiro Elemento de sonda e métodos para separação e deteção de analitos controlada por temperatura
WO2023046901A1 (en) 2021-09-24 2023-03-30 Analog Devices International Unlimited Company, Magnetic field sensing based on particle position within container
US11940502B2 (en) 2021-09-24 2024-03-26 Analog Devices International Unlimited Company Magnetic field sensing based on particle position within container
US12613147B2 (en) 2021-11-12 2026-04-28 Analog Devices International Unlimited Company Temperature sensing with particles in medium material
CN114739544B (zh) * 2022-02-23 2024-06-14 万津实业(赤壁)有限公司 压力监测膜片、组件及压力监测方法
CN114777964B (zh) * 2022-04-02 2024-07-09 太原理工大学 一种磁流变弹性复合薄膜表面应力生物传感器
US12435803B2 (en) 2022-05-27 2025-10-07 Analog Devices International Unlimited Company Flow adjustment based on particle movement in response to magnetic field
CN119816712A (zh) 2022-08-04 2025-04-11 亚德诺半导体国际无限责任公司 基于磁敏材料的位置和/或运动的力检测
US12379433B2 (en) 2022-09-14 2025-08-05 Analog Devices International Unlimited Company Magnetically sensitive particles and magnetic structure
CN120085232A (zh) * 2025-01-24 2025-06-03 哈尔滨工业大学 一种磁矩测量系统及测量方法

Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63108264A (ja) * 1986-10-25 1988-05-13 Nippon Telegr & Teleph Corp <Ntt> 磁気免疫測定方法および該方法を実施するために使用する検査試薬片
JPH0448266A (ja) * 1990-06-15 1992-02-18 Tdk Corp 抗原又は抗体の濃度測定方法
JPH07504986A (ja) * 1992-03-20 1995-06-01 アボツト・ラボラトリーズ 磁気標識した結合要素を用いた磁気制御型結合アッセイ
JPH09505393A (ja) * 1993-10-01 1997-05-27 アメリカ合衆国 磁気抵抗線形変位センサ、角度変位センサおよび可変抵抗器
JPH09509775A (ja) * 1993-10-01 1997-09-30 アメリカ合衆国 超高密度、不揮発性強磁性ランダム・アクセス・メモリ
JPH1078409A (ja) * 1996-09-03 1998-03-24 Kayaba Ind Co Ltd 流体センサ
JPH10513551A (ja) * 1995-01-27 1998-12-22 シェリング アクチェンゲゼルシャフト 被検体の磁気緩和測定での検出のための方法及び化合物並びにそれらの使用

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4225239A (en) * 1979-07-05 1980-09-30 The United States Of America As Represented By The Secretary Of The Navy Magneto-optic bias of ring laser using reflective magneto-optic element at near-grazing incidence
US4823177A (en) * 1988-06-30 1989-04-18 United States Of America As Represented By The Secretary Of The Navy Method and device for magnetizing thin films by the use of injected spin polarized current
US5025416A (en) * 1989-06-01 1991-06-18 The United States Of America As Represented By The Secretary Of The Navy Thin film magnetic memory elements
TW199858B (enExample) * 1990-03-30 1993-02-11 Fujirebio Kk
DE69332699T2 (de) * 1992-11-16 2003-09-18 Nve Corp., Eden Prairie Magnetoresistive struktur mit einer legierungsschicht
US5541868A (en) 1995-02-21 1996-07-30 The United States Of America As Represented By The Secretary Of The Navy Annular GMR-based memory element
US5981297A (en) 1997-02-05 1999-11-09 The United States Of America As Represented By The Secretary Of The Navy Biosensor using magnetically-detected label
US6468809B1 (en) 2000-02-04 2002-10-22 The United States Of America As Represented By The Secretary Of The Navy High efficiency magnetic sensor for magnetic particles

Patent Citations (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS63108264A (ja) * 1986-10-25 1988-05-13 Nippon Telegr & Teleph Corp <Ntt> 磁気免疫測定方法および該方法を実施するために使用する検査試薬片
JPH0448266A (ja) * 1990-06-15 1992-02-18 Tdk Corp 抗原又は抗体の濃度測定方法
JPH07504986A (ja) * 1992-03-20 1995-06-01 アボツト・ラボラトリーズ 磁気標識した結合要素を用いた磁気制御型結合アッセイ
JPH09505393A (ja) * 1993-10-01 1997-05-27 アメリカ合衆国 磁気抵抗線形変位センサ、角度変位センサおよび可変抵抗器
JPH09509775A (ja) * 1993-10-01 1997-09-30 アメリカ合衆国 超高密度、不揮発性強磁性ランダム・アクセス・メモリ
JPH10513551A (ja) * 1995-01-27 1998-12-22 シェリング アクチェンゲゼルシャフト 被検体の磁気緩和測定での検出のための方法及び化合物並びにそれらの使用
JPH1078409A (ja) * 1996-09-03 1998-03-24 Kayaba Ind Co Ltd 流体センサ

Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004117822A (ja) * 2002-09-26 2004-04-15 Toppan Forms Co Ltd 感熱発色性液体トナー受容層形成用塗工液およびそれを用いた感熱発色性静電印刷用シート
JP2007514932A (ja) * 2003-11-12 2007-06-07 ザ・ボード・オブ・トラスティーズ・オブ・ザ・レランド・スタンフォード・ジュニア・ユニバーシティ 磁性ナノ粒子、磁性検出器アレイ、および生物学的分子の検出におけるそれらの使用方法
JP2007538252A (ja) * 2004-05-18 2007-12-27 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ 生体検知において信号対バックグランド比を向上する磁気的な回転
JP2008522150A (ja) * 2004-11-30 2008-06-26 コーニンクレッカ フィリップス エレクトロニクス エヌ ヴィ バイオセンサにおける磁気クロストークを低減する手段及び方法
JP2009002838A (ja) * 2007-06-22 2009-01-08 Canon Inc 検出装置及び検出方法
JP2009115590A (ja) * 2007-11-06 2009-05-28 Tokyo Institute Of Technology バイオセンサ用マーカ、バイオセンサ、及びバイオセンサ用マーカ検出方法
JP2011512517A (ja) * 2008-01-18 2011-04-21 マグアイシー テクノロジーズ インコーポレイテッド アドレス可能な磁気トンネル接合アレイを用いて磁性粒子を検出する装置
JP2014528071A (ja) * 2011-09-14 2014-10-23 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ 外部磁界を必要としない磁気生体センサ
US9927431B2 (en) 2011-09-14 2018-03-27 Regents Of The University Of Minnesota External field—free magnetic biosensor
US9823316B2 (en) 2011-10-19 2017-11-21 Regents Of The University Of Minnesota Magnetic biomedical sensors and sensing system for high-throughput biomolecule testing

Also Published As

Publication number Publication date
KR20030022770A (ko) 2003-03-17
KR100651700B1 (ko) 2006-11-30
US6468809B1 (en) 2002-10-22
EP1299714A1 (en) 2003-04-09
WO2001057506A1 (en) 2001-08-09
US20020197739A1 (en) 2002-12-26
AU2000267514A1 (en) 2001-08-14
EP1299714A4 (en) 2005-03-30
US6764861B2 (en) 2004-07-20
US6844202B2 (en) 2005-01-18
US20030049869A1 (en) 2003-03-13

Similar Documents

Publication Publication Date Title
US6764861B2 (en) Method of making high efficiency magnetic sensor for magnetic particles
TWI295323B (en) Sensor and method for measuring the areal density of magnetic nanoparticles on a micro-array
Miller et al. Detection of a micron-sized magnetic sphere using a ring-shaped anisotropic magnetoresistance-based sensor: A model for a magnetoresistance-based biosensor
US5981297A (en) Biosensor using magnetically-detected label
US6743639B1 (en) Magnetizable bead detector
EP2390651B1 (en) GMR biosensor with enhanced sensitivity
JP5654357B2 (ja) アドレス可能な磁気トンネル接合アレイを用いて磁性粒子を検出する装置
JP5279340B2 (ja) 標的物質検出キットおよび標的物質検出方法
EP2274633B1 (en) Spintronic magnetic nanoparticle sensors with an active area located on a magnetic domain wall
JP4756868B2 (ja) 検出方法
JP4731927B2 (ja) 磁性体センサおよび検出キット
US20070264727A1 (en) High sensitivity sensor for tagged magnetic bead bioassays
Wang et al. Spintronics: materials, devices, and applications
US7651871B2 (en) Device for forming magnetic well for nanoparticles
US20020123079A1 (en) Process for detecting or quantifying a biological rreaction using superparamagnetic label
Hung et al. Biomedical Diagnosing Lab-on-a-Chip
JP2004530103A (ja) 超常磁性標識を用いて生物学的反応を検出または定量する方法
US8334147B2 (en) Bio-sensor with hard-direction field
Liang et al. Magnetoresistive (MR) biosensor
Ahmadi et al. Application of magnetic nanomaterials in magnetic field sensors
WO2001027592A1 (en) Magnetizable bead detector
Djamal Giant magnetoresistance material and its potential for biosensor applications
JP2008101939A (ja) 物質検出装置及び物質検出方法
Mihajlović et al. Solid-State Magnetic Sensors for Bioapplications
Lenssen Magnetoresistive Sensors and Memory

Legal Events

Date Code Title Description
RD04 Notification of resignation of power of attorney

Free format text: JAPANESE INTERMEDIATE CODE: A7424

Effective date: 20060412

A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20070807

A521 Request for written amendment filed

Free format text: JAPANESE INTERMEDIATE CODE: A523

Effective date: 20080613

A977 Report on retrieval

Free format text: JAPANESE INTERMEDIATE CODE: A971007

Effective date: 20100405

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20100810

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110201