JP2003521914A - トランスジェニック哺乳動物の乳汁に産生されるc1インヒビター - Google Patents
トランスジェニック哺乳動物の乳汁に産生されるc1インヒビターInfo
- Publication number
- JP2003521914A JP2003521914A JP2001557910A JP2001557910A JP2003521914A JP 2003521914 A JP2003521914 A JP 2003521914A JP 2001557910 A JP2001557910 A JP 2001557910A JP 2001557910 A JP2001557910 A JP 2001557910A JP 2003521914 A JP2003521914 A JP 2003521914A
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- milk
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- human mammal
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Applications Claiming Priority (9)
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| US18758000P | 2000-03-07 | 2000-03-07 | |
| EP00200810 | 2000-03-07 | ||
| US60/187,580 | 2000-03-07 | ||
| EP00200810.0 | 2000-03-07 | ||
| PCT/NL2001/000068 WO2001057079A2 (en) | 2000-01-31 | 2001-01-31 | C1 inhibitor produced in the milk of transgenic mammals |
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| JP2011270236A Division JP2012050465A (ja) | 2000-01-31 | 2011-12-09 | トランスジェニック哺乳動物の乳汁に産生されるc1インヒビター |
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| JP2003521914A true JP2003521914A (ja) | 2003-07-22 |
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| EP (1) | EP1252184B1 (enExample) |
| JP (1) | JP2003521914A (enExample) |
| AT (1) | ATE382635T1 (enExample) |
| CA (1) | CA2398707C (enExample) |
| DE (2) | DE122011000002I1 (enExample) |
| DK (1) | DK1252184T3 (enExample) |
| ES (1) | ES2299473T3 (enExample) |
| PT (1) | PT1252184E (enExample) |
| WO (1) | WO2001057079A2 (enExample) |
Cited By (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2009520815A (ja) * | 2005-12-21 | 2009-05-28 | ファーミング インテレクチュアル プロパティ ビー.ブイ. | 虚血再灌流障害を予防するためのc1インヒビターの使用 |
| JP2011526495A (ja) * | 2008-06-30 | 2011-10-13 | チョ−エー・ファーム・カンパニー・リミテッド | 豚のαS1カゼイン遺伝子、そのプロモーター、及びその用途 |
| JP2012050465A (ja) * | 2000-01-31 | 2012-03-15 | Pharming Intellectual Pty Bv | トランスジェニック哺乳動物の乳汁に産生されるc1インヒビター |
| JP2016511394A (ja) * | 2013-01-20 | 2016-04-14 | ダイアックス コーポレーション | pKal関連疾病の評価、アッセイおよび治療 |
| JP2021515757A (ja) * | 2018-02-28 | 2021-06-24 | ファーミング・インテレクチュアル・プロパティー・ビー.ブイ. | 子癇前症の治療及び予防 |
| US11754570B2 (en) | 2019-04-16 | 2023-09-12 | Takeda Pharmaceutical Company Limited | Methods for quantitation of functional C1 esterase inhibitor (FC1-INH) |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| DE10112617A1 (de) * | 2001-03-14 | 2002-10-02 | Aventis Behring Gmbh | Verwendung eines C1-Esterase-Inhibitors zur Verhinderung oder Verzögerung der Abstoßung von Xenotransplantaten in Säugetieren |
| PL376318A1 (en) * | 2002-10-17 | 2005-12-27 | Pharming Intellectual Property B.V. | Protein modification |
| EP1947116B1 (en) | 2003-02-10 | 2017-06-21 | 2-BBB Medicines B.V. | Differentially expressed nucleic acids in the blood-brain barrier under inflammatory conditions |
| HUE052154T2 (hu) * | 2003-05-16 | 2021-04-28 | Pharming Intellectual Property B V | Rövid felezési idejû C1 inhibitor tranziens kezeléshez |
| FR2901796A1 (fr) * | 2006-05-31 | 2007-12-07 | Lab Francais Du Fractionnement | Procede d'extraction d'une ou de plusieurs proteines presentes dans du lait |
| FR2901707B1 (fr) | 2006-05-31 | 2017-09-29 | Lab Francais Du Fractionnement | Composition de facteur vii recombinant ou transgenique, chaque molecule de facteur vii possedant deux sites de n-glycosylation a motifs glycanniques definis |
| EP3028716B1 (en) | 2006-10-10 | 2020-09-16 | Regenesance B.V. | Complement inhibition for improved nerve regeneration |
| WO2010087702A1 (en) | 2009-01-30 | 2010-08-05 | Stichting Katholieke Universiteit | TET2 gene as a marker for diagnosing a myelodysuplastic syndrome (MDS) or an acute myeloid leukemia (AML) and determining the prognosis in a subject |
| WO2011034421A1 (en) | 2009-09-16 | 2011-03-24 | Stichting Het Nederlands Kanker Instituut | Fra-1 target genes as drug targets for treating cancer |
| EP2305717A1 (en) | 2009-09-21 | 2011-04-06 | Koninklijke Nederlandse Akademie van Wetenschappen | Inhibiting TNIK for treating colon cancer |
| EP2354244A1 (en) | 2010-02-04 | 2011-08-10 | Stichting Top Institute Food and Nutrition | MBL2 as a marker of liver-specific insulin resistance |
| EP2354245A1 (en) | 2010-02-04 | 2011-08-10 | Stichting Top Institute Food and Nutrition | MBL2 as a marker of hepatic PPAR- activity |
| WO2012026820A2 (en) | 2010-08-27 | 2012-03-01 | Pantarhei Bioscience B.V. | Immunotherapeutic method for treating prostate cancer |
| EP2465928A1 (en) | 2010-12-16 | 2012-06-20 | Academisch Medisch Centrum bij de Universiteit van Amsterdam | Treatment of Th17-mediated diseases |
| EP2866826B1 (en) | 2012-06-27 | 2025-08-06 | Meiragtx UK II Limited | Combination for treating an inflammatory disorder |
| EP2912065A4 (en) | 2012-10-25 | 2016-10-19 | True North Therapeutics Inc | ANTI COMPLEMENT C1S ANTIBODIES AND USES THEREOF |
| RS63212B1 (sr) | 2012-11-02 | 2022-06-30 | Bioverativ Usa Inc | Antikomplementna c1s antitela i njihove primene |
| SI2968434T1 (sl) | 2013-03-15 | 2017-11-30 | Shire Viropharma Incorporated, | C1-INH sestavki za uporabo pri preprečevanju in zdravljenju hereditarnega angioedema (HAE) |
| US10758550B2 (en) | 2013-10-04 | 2020-09-01 | Glenmark Specialty S.A. | Treatment of allergic rhinitis using a combination of mometasone and olopatadine |
| WO2016080830A2 (en) | 2014-11-18 | 2016-05-26 | Pantarhei Bioscience B.V. | Immunotherapeutic method for treating pancreatic cancer |
| BR112017021289A2 (en) | 2015-04-06 | 2018-06-26 | Bioverativ Usa Inc. | humanized anti-c1s antibodies and methods of use |
| WO2017087882A1 (en) * | 2015-11-19 | 2017-05-26 | Shire Human Genetic Therapies, Inc. | Recombinant human c1 esterase inhibitor and uses thereof |
| EP3525583B8 (en) | 2016-10-12 | 2025-09-10 | Bioverativ USA Inc. | Anti-c1s antibodies and methods of use thereof |
| WO2019166572A1 (en) | 2018-02-28 | 2019-09-06 | Pharming Intellectual Property B.V. | Pharmaceutical system for transdermal administration of a c1 -esterase inhibitor |
| EP3895726A1 (en) | 2020-04-17 | 2021-10-20 | Pharming Intellectual Property BV | Using c1 esterase inhibitor to treat viral infection-related acute respiratory distress |
| CA3225079A1 (en) | 2021-07-09 | 2023-01-12 | Bruno Giannetti | Using c1 esterase inhibitor to treat viral infection-related symptoms |
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| JPH10504715A (ja) * | 1994-07-27 | 1998-05-12 | ファーミング ビー.ブイ. | トランスジェニック哺乳動物の乳汁におけるコラーゲンの産生 |
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| JPH05503001A (ja) * | 1989-10-27 | 1993-05-27 | スティッチング セントラール ラボラトリウム ファン デ ブルートトランスフュジエディエンスト ファン ヘット ネデールランツェ ローデ クルイス | C1インヒビターミューティンおよびその利用 |
| WO1992022320A1 (en) * | 1991-06-14 | 1992-12-23 | Genentech, Inc. | C1 inhibitor variants and treating inflammatory response with c1 inhibitor |
| DE4227762A1 (de) * | 1992-08-24 | 1994-03-03 | Behringwerke Ag | Verwendung eines Kallikrein-Inhibitors zur Herstellung eines Arzneimittels zur Prophylaxe und Therapie bestimmter Krankheiten |
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- 2001-01-31 ES ES01906428T patent/ES2299473T3/es not_active Expired - Lifetime
- 2001-01-31 CA CA2398707A patent/CA2398707C/en not_active Expired - Lifetime
- 2001-01-31 DK DK01906428T patent/DK1252184T3/da active
- 2001-01-31 EP EP01906428A patent/EP1252184B1/en not_active Expired - Lifetime
- 2001-01-31 WO PCT/NL2001/000068 patent/WO2001057079A2/en not_active Ceased
- 2001-01-31 PT PT01906428T patent/PT1252184E/pt unknown
- 2001-01-31 JP JP2001557910A patent/JP2003521914A/ja not_active Withdrawn
- 2001-01-31 AT AT01906428T patent/ATE382635T1/de active
- 2001-01-31 DE DE122011000002C patent/DE122011000002I1/de active Pending
- 2001-01-31 DE DE60132169T patent/DE60132169T2/de not_active Expired - Lifetime
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| WO1999051724A1 (en) * | 1998-04-07 | 1999-10-14 | Pharming Intellectual Property B.V. | PURIFICATION OF HUMAN ACID α-GLUCOSIDASE |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2012050465A (ja) * | 2000-01-31 | 2012-03-15 | Pharming Intellectual Pty Bv | トランスジェニック哺乳動物の乳汁に産生されるc1インヒビター |
| JP2009520815A (ja) * | 2005-12-21 | 2009-05-28 | ファーミング インテレクチュアル プロパティ ビー.ブイ. | 虚血再灌流障害を予防するためのc1インヒビターの使用 |
| JP2011526495A (ja) * | 2008-06-30 | 2011-10-13 | チョ−エー・ファーム・カンパニー・リミテッド | 豚のαS1カゼイン遺伝子、そのプロモーター、及びその用途 |
| US9738694B2 (en) | 2008-06-30 | 2017-08-22 | Cho-A Pharm. Co., Ltd. | Gene of porcine alpha-s1 casein, a promoter of the same and use thereof |
| JP2016511394A (ja) * | 2013-01-20 | 2016-04-14 | ダイアックス コーポレーション | pKal関連疾病の評価、アッセイおよび治療 |
| US10690670B2 (en) | 2013-01-20 | 2020-06-23 | Dyax Corp. | Assays for determining levels of plasma protease C1 inhibitor |
| US11892450B2 (en) | 2013-01-20 | 2024-02-06 | Takeda Pharmaceutical Company Limited | Evaluation, assays and treatment of pKal-mediated disorders |
| JP2021515757A (ja) * | 2018-02-28 | 2021-06-24 | ファーミング・インテレクチュアル・プロパティー・ビー.ブイ. | 子癇前症の治療及び予防 |
| US11754570B2 (en) | 2019-04-16 | 2023-09-12 | Takeda Pharmaceutical Company Limited | Methods for quantitation of functional C1 esterase inhibitor (FC1-INH) |
Also Published As
| Publication number | Publication date |
|---|---|
| CA2398707A1 (en) | 2001-08-09 |
| EP1252184B1 (en) | 2008-01-02 |
| EP1252184A2 (en) | 2002-10-30 |
| DK1252184T3 (da) | 2008-02-04 |
| CA2398707C (en) | 2010-10-26 |
| ATE382635T1 (de) | 2008-01-15 |
| DE60132169D1 (de) | 2008-02-14 |
| WO2001057079A2 (en) | 2001-08-09 |
| ES2299473T3 (es) | 2008-06-01 |
| WO2001057079A3 (en) | 2002-08-15 |
| DE60132169T2 (de) | 2008-12-11 |
| DE122011000002I1 (de) | 2011-05-05 |
| PT1252184E (pt) | 2008-04-15 |
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