JP2003519628A - α−Ｄ−ＧＡＬ（１→３）ＧＡＬ−含有オリゴ糖の合成方法 - Google Patents

α−Ｄ−ＧＡＬ（１→３）ＧＡＬ−含有オリゴ糖の合成方法

Info

Publication number
JP2003519628A
JP2003519628A JP2001551083A JP2001551083A JP2003519628A JP 2003519628 A JP2003519628 A JP 2003519628A JP 2001551083 A JP2001551083 A JP 2001551083A JP 2001551083 A JP2001551083 A JP 2001551083A JP 2003519628 A JP2003519628 A JP 2003519628A
Authority
JP
Japan
Prior art keywords
benzyl
acetyl
chlorobenzoyl
benzoyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001551083A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003519628A5 (enExample
Inventor
ローレント ボロナギ
ギュラ デカニー
ニコラス バリー ドリンナン
ジョン パラゲオルギオ
マイケル レオ ウエスト
Original Assignee
アルケミア ピーティーワイ．リミティッド
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from AUPQ5073A external-priority patent/AUPQ507300A0/en
Priority claimed from AUPQ9734A external-priority patent/AUPQ973400A0/en
Application filed by アルケミア ピーティーワイ．リミティッド filed Critical アルケミア ピーティーワイ．リミティッド
Publication of JP2003519628A publication Critical patent/JP2003519628A/ja
Publication of JP2003519628A5 publication Critical patent/JP2003519628A5/ja
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/12—Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by acids having the group -X-C(=X)-X-, or halides thereof, in which each X means nitrogen, oxygen, sulfur, selenium or tellurium, e.g. carbonic acid, carbamic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/04—Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • C07H15/08—Polyoxyalkylene derivatives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02—Acyclic radicals, not substituted by cyclic structures
    • C07H15/14—Acyclic radicals, not substituted by cyclic structures attached to a sulfur, selenium or tellurium atom of a saccharide radical
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00—Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18—Acyclic radicals, substituted by carbocyclic rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00—Indexing scheme relating to specific properties of organic compounds
    • C07B2200/11—Compounds covalently bound to a solid support

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
JP2001551083A 2000-01-13 2001-01-12 α−Ｄ−ＧＡＬ（１→３）ＧＡＬ−含有オリゴ糖の合成方法 Pending JP2003519628A (ja)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
AUPQ5073A AUPQ507300A0 (en) 2000-01-13 2000-01-13 Methods for synthesis of alpha-d-gal(1-3) gal containing oligosaccharides
AU5073 2000-01-13
AUPQ9734A AUPQ973400A0 (en) 2000-08-29 2000-08-29 Methods for synthesis of alpha-d-gal(1-3) gal containing oligosaccharides
AU9734 2000-08-29
PCT/AU2001/000028 WO2001051499A1 (en) 2000-01-13 2001-01-12 METHODS FOR SYNTHESIS OF α-D-GAL (1→3) GAL-CONTAINING OLIGOSACCHARIDES

Publications (2)

Publication Number Publication Date
JP2003519628A true JP2003519628A (ja) 2003-06-24
JP2003519628A5 JP2003519628A5 (enExample) 2005-05-19

Family

ID=25646242

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001551083A Pending JP2003519628A (ja) 2000-01-13 2001-01-12 α−Ｄ−ＧＡＬ（１→３）ＧＡＬ−含有オリゴ糖の合成方法

Country Status (8)

Country Link
US (1) US20040058888A1 (enExample)
EP (1) EP1257558A1 (enExample)
JP (1) JP2003519628A (enExample)
CN (1) CN1395579A (enExample)
CA (1) CA2396966A1 (enExample)
HU (1) HUP0204225A2 (enExample)
IL (1) IL150410A0 (enExample)
WO (1) WO2001051499A1 (enExample)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017525763A (ja) * 2014-08-22 2017-09-07 インスティトゥート ディンベスティガシオ ビオメディカ デ ベルビッチェ（イディベル） 感染症の予防および／または治療のための方法および試薬

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AUPR079700A0 (en) 2000-10-17 2000-11-09 Alchemia Pty Ltd Combinatorial libraries of monosaccharides
AUPS213802A0 (en) 2002-05-03 2002-06-06 Alchemia Pty Ltd Disaccharides for drug discovery
AU2002952121A0 (en) 2002-10-17 2002-10-31 Alchemia Limited Novel carbohydrate based anti-bacterials
WO2009052148A1 (en) * 2007-10-15 2009-04-23 California Institute Of Technology Functionalized polymers using protected thiols
CN102977159A (zh) * 2012-11-18 2013-03-20 大连九信生物化工科技有限公司 一种苄醚保护d-氨基葡萄糖衍生物c3位上羟基的制备方法
NL2023572B1 (en) * 2019-07-25 2021-02-10 Synaffix Bv Synthesis of 6-azido-6-deoxy-2-N-acetyl-hexosamine-nucleoside diphosphate
CN113416220B (zh) * 2021-06-24 2023-07-18 宁波职业技术学院 一种硫代葡萄糖类化合物及其制备方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP3201523B2 (ja) * 1991-08-23 2001-08-20 アルバータ リサーチ カウンスル ヒト受容体における抗体−仲介異種移植拒絶を弱めるための方法および組成物
AU761831B2 (en) * 1998-04-15 2003-06-12 Bioscience 2002 Llc Inhibition of xenoreactive antibodies

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2017525763A (ja) * 2014-08-22 2017-09-07 インスティトゥート ディンベスティガシオ ビオメディカ デ ベルビッチェ（イディベル） 感染症の予防および／または治療のための方法および試薬

Also Published As

Publication number Publication date
CN1395579A (zh) 2003-02-05
CA2396966A1 (en) 2001-07-19
IL150410A0 (en) 2002-12-01
EP1257558A1 (en) 2002-11-20
WO2001051499A1 (en) 2001-07-19
US20040058888A1 (en) 2004-03-25
HUP0204225A2 (en) 2003-05-28

Similar Documents

Publication Publication Date Title
US4675392A (en) Glycosides
Nicolaou et al. Total synthesis of sulfated Lex and Lea-type oligosaccharide selectin ligands
JP4553488B2 (ja) カルボキシメチルガラクトース誘導体
US5763413A (en) Lewis-associated compound, process for producing the same, and anti-inflammatory
DE69635730T2 (de) Synthese des durch den monoklonalen antikörper mbr1 definierten brusttumorassoziierten antigens und seine verwendung
FI75172B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara n-glykosylerade karboksylsyraamidderivat.
CA2197336A1 (en) Sialic acid/fucose based medicaments
USRE34091E (en) Sialic acid derivatives having active carbonyl group
Dahmén et al. Synthesis of spacer-arm, lipid, and ethyl glycosides of the trisaccharide portion [α-d-Gal-(1→ 4)-β-d-Gal-(1→ 4)-β-d-Glc] of the blood-group Pk antigen: Preparation of neoglycoproteins
US20250332267A1 (en) Drug delivery
JPH0343280B2 (enExample)
EP2554549A1 (en) Oligosaccharides and oligosaccharides-protein conjugates derived from clostridium difficile polysaccharide PS-I, methods of synthesis and uses thereof, in particular as vaccines and diagnostic tools
JP2003519628A (ja) α−Ｄ−ＧＡＬ（１→３）ＧＡＬ−含有オリゴ糖の合成方法
Iijima et al. Synthesis of a mucin-type O-glycosylated amino acid, β-Gal-(1→ 3)-[α-Neu5Ac-(2→ 6)]-α-GalNAc-(1→ 3)-Ser
EP0728763B1 (en) Ganglioside gm3 analog having sialic acid residue fluorinated at the 9-position and intermediate therefor
Zhang et al. Synthesis of Double-Chain Bis-sulfone Neoglycolipids of the 2'-, 3'-, and 6'-Deoxyglobotrioses
JP2823358B2 (ja) 免疫抑制性および寛容原性修飾ルイス▲上ｃ▼およびＬａｃＮＡｃ化合物
Cornil et al. Multigram synthesis of an orthogonally-protected pentasaccharide for use as a glycan precursor in a Shigella flexneri 3a conjugate vaccine: application to a ready-for-conjugation decasaccharide
Robina et al. Fatty acylamino-trisaccharides. Synthesis and some stereochemical properties
EP0812855B1 (en) Fluorinated ganglioside gm3 analogues and intermediates therefor
AU2654201A (en) Methods for synthesis of alpha-D-GAL (1-3) GAL-containing oligosaccharides
JPH085914B2 (ja) グリコシル−蛋白誘導体
DE69130235T2 (de) Rezeptor-konjugate zum targeting von arzneiwirkstoffen und anderen wirksubstanzen
JPH069675A (ja) 糖骨格を有する分枝鎖型誘導体
Davidson Synthesis of selected fragments of the Lewis B Lewis A Tumor-Associated Carbohydrate Antigen