JP2003519207A5 - - Google Patents

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Publication number
JP2003519207A5
JP2003519207A5 JP2001550189A JP2001550189A JP2003519207A5 JP 2003519207 A5 JP2003519207 A5 JP 2003519207A5 JP 2001550189 A JP2001550189 A JP 2001550189A JP 2001550189 A JP2001550189 A JP 2001550189A JP 2003519207 A5 JP2003519207 A5 JP 2003519207A5
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JP
Japan
Prior art keywords
formula
compound
defined above
enriched
salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001550189A
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English (en)
Japanese (ja)
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JP2003519207A (ja
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Publication date
Priority claimed from SE9904850A external-priority patent/SE9904850D0/xx
Application filed filed Critical
Publication of JP2003519207A publication Critical patent/JP2003519207A/ja
Publication of JP2003519207A5 publication Critical patent/JP2003519207A5/ja
Pending legal-status Critical Current

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JP2001550189A 1999-12-30 2000-12-22 トルテロジンおよびその類似体の調製方法ならびにこの方法で調製される中間体 Pending JP2003519207A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
SE9904850A SE9904850D0 (sv) 1999-12-30 1999-12-30 Novel process and intermediates
SE9904850-6 1999-12-30
PCT/SE2000/002662 WO2001049649A1 (en) 1999-12-30 2000-12-22 Process of preparing tolterodine and analogues there of as well as intermediates prepared in the process

Publications (2)

Publication Number Publication Date
JP2003519207A JP2003519207A (ja) 2003-06-17
JP2003519207A5 true JP2003519207A5 (https=) 2007-12-06

Family

ID=20418365

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001550189A Pending JP2003519207A (ja) 1999-12-30 2000-12-22 トルテロジンおよびその類似体の調製方法ならびにこの方法で調製される中間体

Country Status (29)

Country Link
US (1) US6310248B2 (https=)
EP (2) EP1242361B1 (https=)
JP (1) JP2003519207A (https=)
KR (1) KR20020062669A (https=)
CN (1) CN1209342C (https=)
AR (1) AR027138A1 (https=)
AT (1) ATE282019T1 (https=)
AU (1) AU782796B2 (https=)
BR (1) BR0016785A (https=)
CA (1) CA2392832A1 (https=)
CZ (1) CZ20022255A3 (https=)
DE (1) DE60015799T2 (https=)
DK (1) DK1242361T3 (https=)
EE (1) EE200200325A (https=)
ES (1) ES2228658T3 (https=)
HU (1) HUP0203816A3 (https=)
IL (1) IL150275A0 (https=)
MX (1) MXPA02006415A (https=)
MY (1) MY118906A (https=)
NO (1) NO20023189L (https=)
NZ (1) NZ519079A (https=)
PE (1) PE20011123A1 (https=)
PL (1) PL355947A1 (https=)
PT (1) PT1242361E (https=)
SE (1) SE9904850D0 (https=)
SK (1) SK9392002A3 (https=)
TW (1) TWI225476B (https=)
WO (1) WO2001049649A1 (https=)
ZA (1) ZA200204066B (https=)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines
US6703504B2 (en) 2002-02-11 2004-03-09 Clarke Slemon Conformationally constrained compounds as dendrimer cores
WO2003064501A1 (en) * 2002-01-31 2003-08-07 Clarke Slemon Conformationally restricted compounds as dendrimer cores
EP1424079A1 (en) * 2002-11-27 2004-06-02 Boehringer Ingelheim International GmbH Combination of a beta-3-receptor agonist and of a reuptake inhibitor of serotonin and/or norepinephrine
DE10315917A1 (de) * 2003-04-08 2004-11-18 Schwarz Pharma Ag Hochreine Basen von 3,3-Diphenylpropylaminmonoestern
ITMI20031354A1 (it) * 2003-07-02 2005-01-03 Istituto Di Chimica Biomolecolare D El Cnr Sezione Sintesis enantioselettiva di composti enantiomericamente arricchiti.
ES2235648B1 (es) * 2003-12-22 2006-11-01 Ragactives, S.L. Procedimiento para la obtencion de tolterodina.
ITMI20040616A1 (it) * 2004-03-30 2004-06-30 Dinamite Dipharma S P A In For Processo per la preparazione di tolterodina e suoi intermedi
EP1629834A1 (en) 2004-08-27 2006-03-01 KRKA, D.D., Novo Mesto Sustained release pharmaceutical composition of tolterodine
ITMI20041920A1 (it) * 2004-10-11 2005-01-11 Chemi Spa Processo per la preparazione di n, n-diisopropil-3-2-idrossi-5-metilfenil-3-fenil-propabammina
JP4513535B2 (ja) * 2004-12-03 2010-07-28 住友化学株式会社 トルテロジンの製造方法
EP1838659B1 (en) * 2004-12-24 2015-07-15 LEK Pharmaceuticals d.d. Process for preparation of n,n-diisopropyl-3-(2-hydroxy-5-methylphenyl)-3-phenylpropylamine
US7528267B2 (en) * 2005-08-01 2009-05-05 Girindus America, Inc. Method for enantioselective hydrogenation of chromenes
ES2268987B1 (es) 2005-08-05 2008-02-01 Ragactives, S.L. Procedimiento para la obtencion de 3,3-difenilpropilaminas.
KR100647068B1 (ko) 2005-09-15 2006-11-23 하나제약 주식회사 라세믹ｎ,ｎ-디이소프로필-3-(2-히드록시-5-메틸페닐)-3-페닐프로판아민의 제조방법
KR100686351B1 (ko) * 2006-01-12 2007-02-22 주식회사 카이로제닉스 톨테로딘 라세미체의 제조방법
DE602007009096D1 (de) 2006-05-24 2010-10-21 Pfizer Ltd Verfahren zur herstellung von benzopyran-2-olderivaten
BRPI0712842A2 (pt) 2006-06-12 2012-07-24 Sanol Arznei Schwarz Gmbh internediÁrio quiral, processo para produÇço do mesmo e seu emprego na fabricaÇço da tolterodina, fesoterodina ou o metabàlito ativo das mesmas.
KR100717361B1 (ko) * 2006-08-07 2007-05-11 주식회사 카이로제닉스 톨테로딘 라세미체 및 이의 중간체의 제조방법
WO2009019599A2 (en) 2007-08-08 2009-02-12 Themis Laboratories Private Limited Extended release compositions comprising tolterodine
HRP20140640T1 (hr) 2008-08-19 2014-11-21 Xenoport, Inc. Prolijekovi monometil estera fumarne kiseline, farmaceutski sastavi iz toga i postupci njihove uporabe
ES2412408T3 (es) 2008-12-24 2013-07-11 Daiichi Sankyo Company, Limited Compuestos de indanilo
CA2748249C (en) 2008-12-24 2013-07-02 Daiichi Sankyo Company, Limited Cyclic amine compounds
KR101275984B1 (ko) * 2010-10-18 2013-06-18 경기대학교 산학협력단 광학활성을 갖는 크로만계 유도체 및 이의 제조방법
EP2639216B1 (en) * 2010-11-09 2018-07-11 Kaneka Corporation Halogenated indenones and method for producing optically active indanones or optically active indanols by using same
WO2012098044A1 (en) 2011-01-17 2012-07-26 Cambrex Profarmaco Milano S.R.L. Process for the preparation of n,n-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate
EP2476665A1 (en) 2011-01-17 2012-07-18 Cambrex Profarmaco Milano S.r.l. Process for the preparation of N,N-diisopropyl-3-(2-hydroxy-5-methylphenyl)- 3-phenyl propylamine and its salts starting from a novel intermediate
PL3135656T3 (pl) 2011-06-20 2019-07-31 H. Lundbeck A/S Deuterowane 1-piperazyno-3-fenyloindany do leczenia schizofrenii
CN103159657B (zh) * 2011-12-08 2016-06-29 重庆华邦胜凯制药有限公司 一种定向合成不饱和共轭醇的方法
AR094054A1 (es) * 2012-12-19 2015-07-08 H Lundbeck As 6-cloro-3-(fenil-d₅)-inden-1-ona y uso de la misma
KR101380982B1 (ko) 2013-04-29 2014-04-10 경기대학교 산학협력단 광학활성을 갖는 크로만-2-올 유도체 및 이의 제조방법
WO2017137955A1 (en) 2016-02-14 2017-08-17 Celestis Pharmaceuticals Pvt. Ltd. Novel (r) and rac 3-(2-(allyloxy)-5-methylphenyl)-n,n-diisopropyl-3- phenylpropan-1-amine and its use for synthesis of (r) and rac-2-(3- (diisopropylamino)-1-phenylpropyl)-4-(hydroxymethyl)phenol
US20210282443A1 (en) * 2016-07-12 2021-09-16 Chromocell Corporation Compounds, compositions, and methods for modulating sweet taste
EP3891134A1 (en) 2018-12-03 2021-10-13 H. Lundbeck A/S Prodrugs of 4-((1r,3s)-6-chloro-3-phenyl-2,3-dihydro-1h-inden-1-yl)-1,2,2-trimethylpiperazine and 4-((1/r,3s)-6-chloro-3-(phenyl-d5)-2,3-dihydro-1h-inden-1-yl)-2,2-dimethy-1-(methyl-d3)piperazine

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE8800207D0 (sv) * 1988-01-22 1988-01-22 Kabivitrum Ab Nya aminer, deras anvendning och framstellning
SE9203318D0 (sv) * 1992-11-06 1992-11-06 Kabi Pharmacia Ab Novel 3,3-diphenylpropylamines, their use and preparation
ZA969363B (en) * 1995-11-08 1997-11-18 Smithkline Beecham Corp An improved process for preparing aromatic ring-fused cyclopentane derivatives.
KR20000057548A (ko) * 1996-12-13 2000-09-25 알프레드 엘. 미첼슨 광학적 전송물질 및 결합재
EP0957073A1 (en) * 1998-05-12 1999-11-17 Schwarz Pharma Ag Novel derivatives of 3,3-diphenylpropylamines

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