JP2003513039A5 - - Google Patents
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- Publication number
- JP2003513039A5 JP2003513039A5 JP2001534373A JP2001534373A JP2003513039A5 JP 2003513039 A5 JP2003513039 A5 JP 2003513039A5 JP 2001534373 A JP2001534373 A JP 2001534373A JP 2001534373 A JP2001534373 A JP 2001534373A JP 2003513039 A5 JP2003513039 A5 JP 2003513039A5
- Authority
- JP
- Japan
- Prior art keywords
- antioxidant
- composition
- carnitine
- administered
- amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000003963 antioxidant agent Substances 0.000 description 4
- 230000003078 antioxidant effect Effects 0.000 description 4
- 235000006708 antioxidants Nutrition 0.000 description 4
- PHIQHXFUZVPYII-ZCFIWIBFSA-O (R)-carnitinium Chemical compound C[N+](C)(C)C[C@H](O)CC(O)=O PHIQHXFUZVPYII-ZCFIWIBFSA-O 0.000 description 2
- 229960004203 carnitine Drugs 0.000 description 2
- CVSVTCORWBXHQV-UHFFFAOYSA-N creatine Chemical compound NC(=[NH2+])N(C)CC([O-])=O CVSVTCORWBXHQV-UHFFFAOYSA-N 0.000 description 2
- AGBQKNBQESQNJD-SSDOTTSWSA-N (R)-lipoic acid Chemical compound OC(=O)CCCC[C@@H]1CCSS1 AGBQKNBQESQNJD-SSDOTTSWSA-N 0.000 description 1
- 208000026139 Memory disease Diseases 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 235000017471 coenzyme Q10 Nutrition 0.000 description 1
- ACTIUHUUMQJHFO-UPTCCGCDSA-N coenzyme Q10 Chemical compound COC1=C(OC)C(=O)C(C\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CC\C=C(/C)CCC=C(C)C)=C(C)C1=O ACTIUHUUMQJHFO-UPTCCGCDSA-N 0.000 description 1
- 229960003624 creatine Drugs 0.000 description 1
- 239000006046 creatine Substances 0.000 description 1
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US16335299P | 1999-11-03 | 1999-11-03 | |
| US22316700P | 2000-08-07 | 2000-08-07 | |
| US60/223,167 | 2000-08-07 | ||
| US60/163,352 | 2000-08-07 | ||
| PCT/US2000/030571 WO2001032168A1 (en) | 1999-11-03 | 2000-11-02 | Method of treating benign forgetfulness |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003513039A JP2003513039A (ja) | 2003-04-08 |
| JP2003513039A5 true JP2003513039A5 (https=) | 2006-01-05 |
Family
ID=26859574
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001534373A Pending JP2003513039A (ja) | 1999-11-03 | 2000-11-02 | 良性の健忘症を治療する方法 |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US6335361B1 (https=) |
| EP (1) | EP1248609A4 (https=) |
| JP (1) | JP2003513039A (https=) |
| CA (1) | CA2389623A1 (https=) |
| WO (1) | WO2001032168A1 (https=) |
Families Citing this family (51)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6616942B1 (en) | 1999-03-29 | 2003-09-09 | Soft Gel Technologies, Inc. | Coenzyme Q10 formulation and process methodology for soft gel capsules manufacturing |
| US20020076470A1 (en) * | 2000-10-31 | 2002-06-20 | Colgate-Palmolive Company | Composition and method |
| US8669282B2 (en) | 2000-10-31 | 2014-03-11 | Hill's Pet Nutrition, Inc. | Companion animal compositions including lipoic acid and methods of use thereof |
| US20090156658A1 (en) * | 2000-10-31 | 2009-06-18 | Hill's Pet Nutrition, Inc. | Antioxidant-Containing Food Composition For Use In Inhibiting Histamine Pathways In Companion Animals |
| CN1477958A (zh) * | 2000-10-31 | 2004-02-25 | 高露洁-棕榄公司 | 组合物及方法 |
| US8592479B2 (en) * | 2000-10-31 | 2013-11-26 | Hill's Pet Nutrition, Inc. | Antioxidant-containing food composition for use in enhancing antiviral immunity in companion animals |
| WO2002038141A2 (en) * | 2000-11-08 | 2002-05-16 | Massachusetts Institute Of Technology | Compositions and methods for treatment of mild cognitive impairment |
| EA006429B1 (ru) * | 2001-03-09 | 2005-12-29 | Сосьете Де Продюи Нестле С.А. | Композиция для предупреждения или восстановления возрастных функциональных дефицитов у млекопитающих и способ ее применения |
| DE10125901A1 (de) * | 2001-05-28 | 2002-12-05 | Basf Ag | Kombination von Liponsäuren, Carnitinen und Kreatinen in Lebens- und Arzneimitteln |
| US6923960B2 (en) | 2001-10-03 | 2005-08-02 | Vsl Pharmaceuticals Inc. | Antioxidant combination composition and use thereof |
| WO2003093299A2 (en) | 2002-05-06 | 2003-11-13 | Thomas Jefferson University | Insulin-associated peptides with effects on cerebral health |
| EP1567180A4 (en) * | 2002-06-04 | 2010-03-10 | Avicena Group Inc | METHOD FOR THE TREATMENT OF COGNITIVE DYSFUNCTION BY MODULATING THE CHANGE OF ENERGY REPLACEMENT IN THE BRAIN |
| US7030154B2 (en) | 2002-06-07 | 2006-04-18 | Juvenon, Inc. | Stability of lipoic acid |
| US7326690B2 (en) * | 2002-10-30 | 2008-02-05 | Bach Pharma, Inc. | Modulation of cell fates and activities by phthalazinediones |
| EP1558244A2 (en) * | 2002-11-07 | 2005-08-03 | DSM IP Assets B.V. | Novel nutraceutical compositions comprising epigallocatechin gallate |
| US8173618B2 (en) * | 2003-07-25 | 2012-05-08 | University Of Massachusetts | Formulations for reducing neuronal degeneration |
| US20080089877A1 (en) * | 2003-08-14 | 2008-04-17 | Udell Ronald G | Super Absorption Coenzyme Q10 |
| US8124072B2 (en) | 2003-09-29 | 2012-02-28 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| US7169385B2 (en) * | 2003-09-29 | 2007-01-30 | Ronald G. Udell | Solubilized CoQ-10 and carnitine |
| US8105583B2 (en) * | 2003-09-29 | 2012-01-31 | Soft Gel Technologies, Inc. | Solubilized CoQ-10 |
| US20050102171A1 (en) * | 2003-10-29 | 2005-05-12 | Ashley Thomas R. | Elderly assessment protocol |
| US20090176864A1 (en) * | 2004-11-24 | 2009-07-09 | Hill's Pet Nutrition, Inc. | Methods For Improving Hepatic and Immune Function In An Animal |
| EP1817058B1 (en) * | 2004-11-24 | 2015-09-02 | Hill's Pet Nutrition, Inc. | Composition for use in improving liver clearance of xenobiotic substances in an animal |
| CA2592389C (en) * | 2004-12-29 | 2013-05-14 | Hill's Pet Nutrition, Inc. | Methods for inhibiting a decline in learning and/or memory in animals |
| AU2005322887B2 (en) * | 2004-12-30 | 2010-03-11 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| US8252742B2 (en) * | 2004-12-30 | 2012-08-28 | Hill's Pet Nutrition, Inc. | Methods for enhancing the quality of life of a senior animal |
| WO2006092449A2 (en) * | 2005-03-02 | 2006-09-08 | Metanomics Gmbh | Process for the production of fine chemicals |
| BRPI0613000A2 (pt) | 2005-07-14 | 2012-12-04 | Hills Pet Nutrition Inc | método para aumentar a longevidade de um animal, artigo de fabricação, kit, e, meio de comunicação de informação acerca de ou instruções para a administração a um animal velho de uma composição |
| TW200812567A (en) | 2006-03-29 | 2008-03-16 | Kaneka Corp | Agent for improving nervous system cell functions |
| AU2007249847A1 (en) * | 2006-05-11 | 2007-11-22 | Avicena Group, Inc. | Methods of treating a neurological disorder with creatine monohydrate |
| JP5119509B2 (ja) * | 2006-05-18 | 2013-01-16 | ビーエイチエヌ株式会社 | 活動意欲向上剤 |
| US8071610B2 (en) * | 2006-06-05 | 2011-12-06 | Josh Reynolds | Compositions and methods for enhancing brain function |
| US10105405B2 (en) | 2006-06-05 | 2018-10-23 | Keyview Labs, Inc. | Compositions and methods for enhancing brain function using acetyl-L-carnitine, huperzine A and ginkgo biloba |
| US20070281961A1 (en) * | 2006-06-05 | 2007-12-06 | Brite Age | Modified Compositions And Methods For Enhancing Brain Function |
| US9308232B2 (en) | 2006-06-05 | 2016-04-12 | Keyview Labs, Inc. | Compositions and methods for enhancing brain function |
| US10105406B2 (en) | 2006-06-05 | 2018-10-23 | Keyview Labs, Inc. | Compositions and methods for enhancing brain function using acetyl-L-carnitine, huperzine A, Ginkgo biloba, and vitamin B complex |
| WO2007145993A2 (en) * | 2006-06-05 | 2007-12-21 | Brite Age | Modified compositions and methods for enhancing brain function |
| US8883814B2 (en) | 2006-06-05 | 2014-11-11 | Keyview Labs, Inc. | Compositions and methods for enhancing brain function |
| EP1929995A1 (en) | 2006-12-04 | 2008-06-11 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Anaplerotic therapy of Huntington disease and other polyglutamine diseases |
| JP2008214338A (ja) * | 2007-02-08 | 2008-09-18 | Shiseido Co Ltd | 高次脳機能低下改善剤および遅延記憶低下改善剤 |
| US20080226696A1 (en) * | 2007-03-15 | 2008-09-18 | Ben Treadwell | Methods of improving learning abilities of aged companion animals |
| US8343541B2 (en) * | 2007-03-15 | 2013-01-01 | Soft Gel Technologies, Inc. | Ubiquinol and alpha lipoic acid compositions |
| WO2008119109A1 (en) * | 2007-03-29 | 2008-10-09 | Velacor Therapeutics Pty Ltd | Treatment of neurological disorders |
| JP5157007B2 (ja) * | 2007-05-11 | 2013-03-06 | ビーエイチエヌ株式会社 | 骨強化剤 |
| DE102007030495A1 (de) | 2007-06-30 | 2009-01-15 | Alzchem Trostberg Gmbh | Verwendung einer eine Kreatin-Komponente enthaltende Zusammensetzung zur Verbesserung der Gedächtnisleistung, der Merkfähigkeit, des Langzeitgedächtnisses und zur Vorbeugung geistiger Ermüdungszustände |
| US8597640B2 (en) * | 2007-10-31 | 2013-12-03 | University Of Massachusetts Lowell | Over-the-counter vitamin/nutriceutical formulation that provides neuroprotection and maintains or improves cognitive performance in alzheimer's disease and normal aging |
| KR20120129898A (ko) | 2009-12-30 | 2012-11-28 | 베일러 리서치 인스티튜트 | 알츠하이머 질환 및 노화 뇌를 위한 보충대사 치료요법 |
| CA2894456C (en) | 2012-12-13 | 2022-06-28 | Baylor Research Institute | Triheptanoin for the treatment of glucose transporter 1 deficiency |
| ES2774321T3 (es) | 2013-11-14 | 2020-07-20 | Univ Queensland | Trastornos neurodegenerativos y métodos de tratamiento y diagnóstico de los mismos |
| JP2015193582A (ja) * | 2014-03-28 | 2015-11-05 | 国立大学法人 東京大学 | イミダゾールジペプチドを含む剤 |
| CN112190688A (zh) * | 2020-09-09 | 2021-01-08 | 广州医科大学附属第一医院（广州呼吸中心） | 粘蛋白muc1在制备具有延缓肺衰老功效的药物中的应用 |
Family Cites Families (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3810994A (en) * | 1972-06-01 | 1974-05-14 | Ethyl Corp | Method and composition for treating obesity |
| IT1156840B (it) | 1978-06-27 | 1987-02-04 | Sigma Tau Ind Farmaceuti | Acil derivati della carnitina |
| US4346107A (en) * | 1979-02-12 | 1982-08-24 | Claudio Cavazza | Pharmaceutical composition comprising acyl-carnitine for the treatment of impaired cerebral metabolism |
| IT1145362B (it) | 1980-03-06 | 1986-11-05 | Sigma Tau Ind Farmaceuti | Classe di acil-derivati della carnitina procedimento per la loro preparazione e loro uso terapeutico |
| CH655005A5 (it) | 1983-02-16 | 1986-03-27 | Sigma Tau Ind Farmaceuti | Composizione farmaceutica ad azione metabolica ed energetica utilizzabile in terapia cardiaca e vascolare. |
| US4871718A (en) | 1987-12-29 | 1989-10-03 | Raymond A. Roncari | Composition of matter for increasing intracellular ATP levels and physical performance levels and for increasing the rate of wound repair |
| IT1230142B (it) | 1989-05-03 | 1991-10-14 | Fidia Spa | Derivati della carnitina, processo per la loro preparazione e impiego in terapia umana |
| US5240961A (en) | 1992-07-02 | 1993-08-31 | Shug Austin L | Method of treating reduced insulin-like growth factor and bone loss associated with aging |
| US5977162A (en) * | 1996-09-16 | 1999-11-02 | Seidman; Michael D. | Therapeutic treatment for auditory function |
| US5916912A (en) * | 1997-06-16 | 1999-06-29 | The Regents Of The University Of California | Dietary composition for enhancing metabolism and alleviating oxidative stress |
| IT1302307B1 (it) * | 1998-09-01 | 2000-09-05 | Sigma Tau Healthscience Spa | Composizione ad attivita' antiossidante ed atta a migliorarel'utilizzazione metabolica del glucosio, comprendente acetil |
-
2000
- 2000-11-02 JP JP2001534373A patent/JP2003513039A/ja active Pending
- 2000-11-02 CA CA002389623A patent/CA2389623A1/en not_active Abandoned
- 2000-11-02 WO PCT/US2000/030571 patent/WO2001032168A1/en not_active Ceased
- 2000-11-02 US US09/706,207 patent/US6335361B1/en not_active Expired - Lifetime
- 2000-11-02 EP EP00980294A patent/EP1248609A4/en not_active Withdrawn
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