JP2003513028A - 肺疾患を治療するための方法および組成物 - Google Patents

肺疾患を治療するための方法および組成物

Info

Publication number
JP2003513028A
JP2003513028A JP2001534335A JP2001534335A JP2003513028A JP 2003513028 A JP2003513028 A JP 2003513028A JP 2001534335 A JP2001534335 A JP 2001534335A JP 2001534335 A JP2001534335 A JP 2001534335A JP 2003513028 A JP2003513028 A JP 2003513028A
Authority
JP
Japan
Prior art keywords
pde4
rolipram
compounds
activity
asthma
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001534335A
Other languages
English (en)
Japanese (ja)
Inventor
ピーター・エヌ・グッドフェロー
リチャード・ニーマン
セオドア・ジェイ・トーフィー
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of JP2003513028A publication Critical patent/JP2003513028A/ja
Pending legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
JP2001534335A 1999-11-02 2000-11-01 肺疾患を治療するための方法および組成物 Pending JP2003513028A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02
US60/163,158 1999-11-02
PCT/US2000/030113 WO2001032127A2 (fr) 1999-11-02 2000-11-01 Procede et compositions pour traiter des maladies respiratoires

Publications (1)

Publication Number Publication Date
JP2003513028A true JP2003513028A (ja) 2003-04-08

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001534335A Pending JP2003513028A (ja) 1999-11-02 2000-11-01 肺疾患を治療するための方法および組成物

Country Status (29)

Country Link
EP (1) EP1225866A4 (fr)
JP (1) JP2003513028A (fr)
KR (1) KR20020057988A (fr)
CN (1) CN1387404A (fr)
AP (1) AP2002002496A0 (fr)
AR (1) AR029189A1 (fr)
AU (1) AU1357501A (fr)
BG (1) BG106748A (fr)
BR (1) BR0015270A (fr)
CA (1) CA2388333A1 (fr)
CO (1) CO5261512A1 (fr)
CZ (1) CZ20021512A3 (fr)
DZ (1) DZ3225A1 (fr)
EA (1) EA200200518A1 (fr)
EC (1) ECSP003747A (fr)
HK (1) HK1049107A1 (fr)
HU (1) HUP0203152A3 (fr)
IL (1) IL149367A0 (fr)
MA (1) MA26841A1 (fr)
MX (1) MXPA02004350A (fr)
NO (1) NO20022057L (fr)
OA (1) OA12076A (fr)
PE (1) PE20011005A1 (fr)
PL (1) PL355261A1 (fr)
SK (1) SK7592002A3 (fr)
TR (1) TR200201211T2 (fr)
TW (1) TWI242431B (fr)
WO (1) WO2001032127A2 (fr)
ZA (1) ZA200203435B (fr)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006041121A1 (fr) * 2004-10-13 2006-04-20 Kyowa Hakko Kogyo Co., Ltd. Traitements prophylactiques ou thérapeutiques de maladie chronique de la peau

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2459757C (fr) * 2001-09-19 2011-08-30 Altana Pharma Ag Combinaison
MXPA04003668A (es) * 2001-10-31 2004-07-22 Merck Patent Gmbh Inhibidores de fosfodiesteresa de tipo 4 y usos de los mismos.
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
WO2004087149A1 (fr) * 2003-03-31 2004-10-14 Kyowa Hakko Kogyo Co. Ltd. Composition therapeutique
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
WO2007045980A1 (fr) * 2005-10-19 2007-04-26 Ranbaxy Laboratories Limited Compositions d'inhibiteurs de la phosphodiesterase de type iv
US8991390B2 (en) 2010-01-05 2015-03-31 Microdose Therapeutx, Inc. Inhalation device and method
WO2015063669A1 (fr) 2013-10-30 2015-05-07 Wockhardt Limited Compositions pharmaceutiques comprenant une combinaison de roflumilast et d'acébrophylline ou de leurs sels pharmaceutiquement acceptables

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11286447A (ja) * 1994-01-27 1999-10-19 Schering Plough Corp 気道流路および肺疾患の処置のためのモメタゾンフロエートの使用
WO1999053926A1 (fr) * 1998-04-20 1999-10-28 Astrazeneca Ab Utilisation d'un glucocorticosteroide dans la preparation d'un medicament permettant de traiter les formes legeres/precoces de bpco (bronchopneumopathie chronique obstructive)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7174794A (en) * 1993-06-18 1995-01-17 Smithkline Beecham Corporation Compounds
DE4332041C2 (de) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Verwendung von Pentoxifyllin bei bestimmten Lungenerkrankungen

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH11286447A (ja) * 1994-01-27 1999-10-19 Schering Plough Corp 気道流路および肺疾患の処置のためのモメタゾンフロエートの使用
WO1999053926A1 (fr) * 1998-04-20 1999-10-28 Astrazeneca Ab Utilisation d'un glucocorticosteroide dans la preparation d'un medicament permettant de traiter les formes legeres/precoces de bpco (bronchopneumopathie chronique obstructive)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2006041121A1 (fr) * 2004-10-13 2006-04-20 Kyowa Hakko Kogyo Co., Ltd. Traitements prophylactiques ou thérapeutiques de maladie chronique de la peau

Also Published As

Publication number Publication date
EP1225866A4 (fr) 2004-04-21
CN1387404A (zh) 2002-12-25
AR029189A1 (es) 2003-06-18
WO2001032127A3 (fr) 2001-12-06
TWI242431B (en) 2005-11-01
PL355261A1 (en) 2004-04-05
OA12076A (en) 2006-05-04
IL149367A0 (en) 2002-11-10
HK1049107A1 (zh) 2003-05-02
PE20011005A1 (es) 2001-09-28
NO20022057D0 (no) 2002-04-30
ECSP003747A (es) 2002-05-23
CO5261512A1 (es) 2003-03-31
AU1357501A (en) 2001-05-14
CZ20021512A3 (cs) 2003-04-16
SK7592002A3 (en) 2002-11-06
CA2388333A1 (fr) 2001-05-10
KR20020057988A (ko) 2002-07-12
WO2001032127A2 (fr) 2001-05-10
NO20022057L (no) 2002-06-27
EA200200518A1 (ru) 2002-10-31
MXPA02004350A (es) 2002-11-07
HUP0203152A3 (en) 2004-06-28
BG106748A (en) 2003-02-28
MA26841A1 (fr) 2004-12-20
HUP0203152A2 (hu) 2003-01-28
TR200201211T2 (tr) 2002-08-21
DZ3225A1 (fr) 2001-05-10
BR0015270A (pt) 2002-06-18
EP1225866A2 (fr) 2002-07-31
ZA200203435B (en) 2003-06-25
AP2002002496A0 (en) 2002-06-30

Similar Documents

Publication Publication Date Title
US6555583B2 (en) Therapies for treating pulmonary diseases
US20050070514A1 (en) Therapies for treating respiratory diseases
US20060004076A1 (en) Co-administration of dehydroepiandrosterone (DHEA) congener with pharmaceutically active agents for treating inflammation
US20060069155A1 (en) Method for reducing exacerbations associated with COPD
EP2958573B1 (fr) Formulations pharmaceutiques de nitrite et leurs utilisations
US20040176419A1 (en) Composition comprising a pde-4 inhibitor and h1-receptor antagonist and the use thereof for the manufacture of a medicament for the treatment of respiratory diseases
JP2003513028A (ja) 肺疾患を治療するための方法および組成物
JP2005539042A (ja) 呼吸器疾患、アレルギー性疾患、喘息及びｃｏｐｄを処置するためのグルココルチコイド及びｐｄｅ−４−阻害剤の新規組合せ
US20080299207A1 (en) Methods and compositions for administration of oxybutynin
KR20060011783A (ko) 데하이드로에피안드로스테론 스테로이드 및항-무스카린제와 더불어 호흡기 및 폐 질환을 치료하기위한 조성물, 제제 및 키트
Meltzer Pharmacological treatment options for allergic rhinitis and asthma.
JP2004505039A (ja) Ｃｏｐｄに付随する増悪の減少方法
JP2003522142A (ja) 炎症性疾患の治療法および治療用組成物
US20060035877A1 (en) Method and compositions for treating pulmonary diseases
AU2003292120A1 (en) New synergistic combination comprising roflumilast and formoterol
AU2003288169B2 (en) Synergistic combination comprising roflumilast and (R,R) -formoterol
AU2004205324A1 (en) Method and compositions for treating pulmonary diseases
AU2002310620A1 (en) Composition comprising a PDE-4 inhibitor and H1-receptor antagonist and the use thereof for the manufacture of a medicament for the treatment respiratory diseases

Legal Events

Date Code Title Description
A621 Written request for application examination

Free format text: JAPANESE INTERMEDIATE CODE: A621

Effective date: 20071101

A131 Notification of reasons for refusal

Free format text: JAPANESE INTERMEDIATE CODE: A131

Effective date: 20110329

A02 Decision of refusal

Free format text: JAPANESE INTERMEDIATE CODE: A02

Effective date: 20110920