CA2388333A1 - Procede et compositions pour traiter des maladies respiratoires - Google Patents

Procede et compositions pour traiter des maladies respiratoires Download PDF

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Publication number
CA2388333A1
CA2388333A1 CA002388333A CA2388333A CA2388333A1 CA 2388333 A1 CA2388333 A1 CA 2388333A1 CA 002388333 A CA002388333 A CA 002388333A CA 2388333 A CA2388333 A CA 2388333A CA 2388333 A1 CA2388333 A1 CA 2388333A1
Authority
CA
Canada
Prior art keywords
rolipram
pde
compounds
asthma
pde4
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002388333A
Other languages
English (en)
Inventor
Peter N. Goodfellow
Richard Nieman
Theodore J. Torphy
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
SmithKline Beecham Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2388333A1 publication Critical patent/CA2388333A1/fr
Abandoned legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pulmonology (AREA)
  • Epidemiology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

L'invention concerne le traitement de maladies respiratoires telles que la maladie respiratoire obstructive chronique ou l'asthme par l'administration d'un inhibiteur de phosphodiestérase 4 en combinaison avec un corticostéroïde anti-inflammatoire.
CA002388333A 1999-11-02 2000-11-01 Procede et compositions pour traiter des maladies respiratoires Abandoned CA2388333A1 (fr)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US16315899P 1999-11-02 1999-11-02
US60/163,158 1999-11-02
PCT/US2000/030113 WO2001032127A2 (fr) 1999-11-02 2000-11-01 Procede et compositions pour traiter des maladies respiratoires

Publications (1)

Publication Number Publication Date
CA2388333A1 true CA2388333A1 (fr) 2001-05-10

Family

ID=22588737

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002388333A Abandoned CA2388333A1 (fr) 1999-11-02 2000-11-01 Procede et compositions pour traiter des maladies respiratoires

Country Status (29)

Country Link
EP (1) EP1225866A4 (fr)
JP (1) JP2003513028A (fr)
KR (1) KR20020057988A (fr)
CN (1) CN1387404A (fr)
AP (1) AP2002002496A0 (fr)
AR (1) AR029189A1 (fr)
AU (1) AU1357501A (fr)
BG (1) BG106748A (fr)
BR (1) BR0015270A (fr)
CA (1) CA2388333A1 (fr)
CO (1) CO5261512A1 (fr)
CZ (1) CZ20021512A3 (fr)
DZ (1) DZ3225A1 (fr)
EA (1) EA200200518A1 (fr)
EC (1) ECSP003747A (fr)
HK (1) HK1049107A1 (fr)
HU (1) HUP0203152A3 (fr)
IL (1) IL149367A0 (fr)
MA (1) MA26841A1 (fr)
MX (1) MXPA02004350A (fr)
NO (1) NO20022057L (fr)
OA (1) OA12076A (fr)
PE (1) PE20011005A1 (fr)
PL (1) PL355261A1 (fr)
SK (1) SK7592002A3 (fr)
TR (1) TR200201211T2 (fr)
TW (1) TWI242431B (fr)
WO (1) WO2001032127A2 (fr)
ZA (1) ZA200203435B (fr)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE60218497T2 (de) 2001-09-19 2007-11-08 Nycomed Gmbh Kombination eines nsaids und eines pde-4 inhibitors
WO2003037349A1 (fr) * 2001-10-31 2003-05-08 Merck Patent Gmbh Inhibiteurs de la phosphodiesterase de type 4 et leurs utilisations
UA82323C2 (uk) * 2002-08-09 2008-04-10 Меда Фарма Гмбх & Ко. Кг Нова комбінація глюкокортикоїду та pde-інгібітору для лікування респіраторних захворювань, алергічних захворювань, астми та хронічних обструктивних легеневих захворювань
TW200410923A (en) * 2002-10-17 2004-07-01 Ono Pharmaceutical Co Therapeutic agent for chronic obstructive pulmonary disease
EP1616569A1 (fr) * 2003-03-31 2006-01-18 Kyowa Hakko Kogyo Co., Ltd. Composition therapeutique
US20050026883A1 (en) * 2003-07-31 2005-02-03 Robinson Cynthia B. Combination of dehydroepiandrosterone or dehydroepiandrosterone-sulfate with a PDE-4 inhibitor for treatment of asthma or chronic obstructive pulmonary disease
CA2584169A1 (fr) * 2004-10-13 2006-04-20 Kyowa Hakko Kogyo Co., Ltd. Traitements prophylactiques ou therapeutiques de maladie chronique de la peau
JP2009512677A (ja) * 2005-10-19 2009-03-26 ランバクシー ラボラトリーズ リミテッド ホスホジエステラーゼタイプｉｖ阻害剤の組成物
CN105381524A (zh) 2010-01-05 2016-03-09 微剂量治疗技术公司 吸入设备和方法
WO2015063669A1 (fr) 2013-10-30 2015-05-07 Wockhardt Limited Compositions pharmaceutiques comprenant une combinaison de roflumilast et d'acébrophylline ou de leurs sels pharmaceutiquement acceptables

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0710109B1 (fr) * 1993-06-18 2004-09-15 Smithkline Beecham Corporation Méthode d'identification d'un inhibiteur de la PDE IV
DE4332041C2 (de) * 1993-09-21 1997-12-11 Rentschler Arzneimittel Verwendung von Pentoxifyllin bei bestimmten Lungenerkrankungen
PE44995A1 (es) * 1994-01-27 1995-12-18 Schering Corp Furoato de mometasona para el tratamiento de las enfermedades pulmonares y de las vias respiratorias
SE9801368D0 (sv) * 1998-04-20 1998-04-20 Astra Ab New use

Also Published As

Publication number Publication date
EP1225866A4 (fr) 2004-04-21
CO5261512A1 (es) 2003-03-31
NO20022057D0 (no) 2002-04-30
MXPA02004350A (es) 2002-11-07
AP2002002496A0 (en) 2002-06-30
WO2001032127A3 (fr) 2001-12-06
MA26841A1 (fr) 2004-12-20
TR200201211T2 (tr) 2002-08-21
CN1387404A (zh) 2002-12-25
PE20011005A1 (es) 2001-09-28
ECSP003747A (es) 2002-05-23
NO20022057L (no) 2002-06-27
WO2001032127A2 (fr) 2001-05-10
AR029189A1 (es) 2003-06-18
AU1357501A (en) 2001-05-14
HK1049107A1 (zh) 2003-05-02
KR20020057988A (ko) 2002-07-12
EP1225866A2 (fr) 2002-07-31
JP2003513028A (ja) 2003-04-08
HUP0203152A3 (en) 2004-06-28
BR0015270A (pt) 2002-06-18
HUP0203152A2 (hu) 2003-01-28
ZA200203435B (en) 2003-06-25
CZ20021512A3 (cs) 2003-04-16
OA12076A (en) 2006-05-04
DZ3225A1 (fr) 2001-05-10
TWI242431B (en) 2005-11-01
SK7592002A3 (en) 2002-11-06
BG106748A (en) 2003-02-28
PL355261A1 (en) 2004-04-05
IL149367A0 (en) 2002-11-10
EA200200518A1 (ru) 2002-10-31

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued