JP2003511550A5 - - Google Patents

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Publication number
JP2003511550A5
JP2003511550A5 JP2001531088A JP2001531088A JP2003511550A5 JP 2003511550 A5 JP2003511550 A5 JP 2003511550A5 JP 2001531088 A JP2001531088 A JP 2001531088A JP 2001531088 A JP2001531088 A JP 2001531088A JP 2003511550 A5 JP2003511550 A5 JP 2003511550A5
Authority
JP
Japan
Prior art keywords
composition
polyanhydride
iii
formula
hydroxy acid
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP2001531088A
Other languages
English (en)
Japanese (ja)
Other versions
JP2003511550A (ja
Filing date
Publication date
Priority claimed from US09/422,294 external-priority patent/US6468519B1/en
Application filed filed Critical
Publication of JP2003511550A publication Critical patent/JP2003511550A/ja
Publication of JP2003511550A5 publication Critical patent/JP2003511550A5/ja
Pending legal-status Critical Current

Links

JP2001531088A 1999-10-21 2000-10-11 生物学的に活性な分解産物を有するポリ酸無水物 Pending JP2003511550A (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US09/422,294 1999-10-21
US09/422,294 US6468519B1 (en) 1997-09-10 1999-10-21 Polyanhydrides with biologically active degradation products
PCT/US2000/027962 WO2001028492A2 (en) 1999-10-21 2000-10-11 Polyanhydrides with biologically active degradation products

Publications (2)

Publication Number Publication Date
JP2003511550A JP2003511550A (ja) 2003-03-25
JP2003511550A5 true JP2003511550A5 (enExample) 2007-11-29

Family

ID=23674230

Family Applications (1)

Application Number Title Priority Date Filing Date
JP2001531088A Pending JP2003511550A (ja) 1999-10-21 2000-10-11 生物学的に活性な分解産物を有するポリ酸無水物

Country Status (9)

Country Link
US (2) US6468519B1 (enExample)
EP (2) EP1464673A3 (enExample)
JP (1) JP2003511550A (enExample)
AT (1) ATE314078T1 (enExample)
AU (1) AU7877100A (enExample)
CA (1) CA2387558A1 (enExample)
DE (1) DE60025272D1 (enExample)
MX (1) MXPA02003890A (enExample)
WO (1) WO2001028492A2 (enExample)

Families Citing this family (51)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US7122615B1 (en) * 1998-09-10 2006-10-17 Rutgers, The State University Of New Jersey Polyanhydrides with therapeutically useful degradation products
US6468519B1 (en) * 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
US7985415B2 (en) * 1997-09-10 2011-07-26 Rutgers, The State University Of New Jersey Medical devices employing novel polymers
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
JP2003528044A (ja) * 1999-12-07 2003-09-24 ラトガーズ， ザ ステイト ユニバーシティ オブ ニュー ジャージー 治療組成物および治療方法
US6527801B1 (en) 2000-04-13 2003-03-04 Advanced Cardiovascular Systems, Inc. Biodegradable drug delivery material for stent
MXPA03000821A (es) * 2000-07-27 2004-03-18 Univ Rutgers Poliesteres y poliamidas terapeuticos.
US6602915B2 (en) 2000-07-27 2003-08-05 Rutgers, The State University Of New Jersey Therapeutic azo-compounds for drug delivery
AU2002357762A1 (en) * 2001-11-23 2003-06-10 Theodore James Anastasion Improved synthesis of polyanhyrides
AU2003251992A1 (en) * 2002-07-17 2004-02-02 Rutgers, The State University Therapeutic devices for patterned cell growth
US7285287B2 (en) 2002-11-14 2007-10-23 Synecor, Llc Carbon dioxide-assisted methods of providing biocompatible intraluminal prostheses
US6932930B2 (en) 2003-03-10 2005-08-23 Synecor, Llc Intraluminal prostheses having polymeric material with selectively modified crystallinity and methods of making same
US9445901B2 (en) * 2003-03-12 2016-09-20 Deger C. Tunc Prosthesis with sustained release analgesic
WO2004100926A2 (en) * 2003-05-13 2004-11-25 Medtronic, Inc. Delivery of agents using hydrolyzable leaving groups
WO2005039489A2 (en) * 2003-09-24 2005-05-06 Polymerix Corporation Compositions and methods for the inhibition of bone growth and resorption
US8352712B2 (en) * 2004-05-06 2013-01-08 International Business Machines Corporation Method and system for specualtively sending processor-issued store operations to a store queue with full signal asserted
AU2005244037A1 (en) * 2004-05-14 2005-11-24 Interface Biologics Inc. Polymeric coupling agents and pharmaceutically-active polymers made therefrom
CA2467321A1 (en) * 2004-05-14 2005-11-14 Paul J. Santerre Polymeric coupling agents and pharmaceutically-active polymers made therefrom
US7858077B2 (en) * 2005-01-28 2010-12-28 Bezwada Biomedical Llc Functionalized phenolic esters and amides and polymers therefrom
US7691364B2 (en) * 2005-01-28 2010-04-06 Bezwada Biomedical, Llc Functionalized drugs and polymers derived therefrom
US20060193891A1 (en) * 2005-02-25 2006-08-31 Robert Richard Medical devices and therapeutic delivery devices composed of bioabsorbable polymers produced at room temperature, method of making the devices, and a system for making the devices
JP2008545695A (ja) * 2005-05-23 2008-12-18 ラトガーズ， ザ ステイト ユニバーシティ オブ ニュー ジャージー 迅速分解ポリマー
US8318973B2 (en) * 2005-10-21 2012-11-27 Bezwada Biomedical, Llc Functionalized sinapic acid and methyl sinapate
US8007526B2 (en) 2005-12-01 2011-08-30 Bezwada Biomedical, Llc Difunctionalized aromatic compounds and polymers therefrom
US7935843B2 (en) * 2005-12-09 2011-05-03 Bezwada Biomedical, Llc Functionalized diphenolics and absorbable polymers therefrom
US9603941B2 (en) * 2006-01-24 2017-03-28 Minghui Chai Method of preparing dendritic drugs
US20070225472A1 (en) * 2006-03-23 2007-09-27 Varshney Sunil K Polyanhydride polymers and their uses in biomedical devices
EP2032614A2 (en) * 2006-06-06 2009-03-11 Rutgers, The State University Of New Jersey Iodinated polymers
EP2102144A4 (en) 2006-09-13 2011-03-23 Univ Rutgers ACTIVE SUBSTANCES AND THEIR OLIGOMERS AND POLYMERS
CA2667325A1 (en) * 2006-10-23 2008-05-02 Bioabsorbable Therapeutics, Inc. A drug-release composition having a therapeutic carrier
WO2008057501A2 (en) * 2006-11-06 2008-05-15 Whitehead Institute Immunomodulating compositions and methods of use thereof
US9457047B2 (en) 2006-11-06 2016-10-04 Whitehead Institute Immunomodulating compositions and methods of use thereof
US8747832B2 (en) * 2007-04-12 2014-06-10 Rutgers, The State University Of New Jersey Biodegradable polyanhydrides with natural bioactive molecules
US8217134B2 (en) 2007-08-30 2012-07-10 Bezwada Biomedical, Llc Controlled release of biologically active compounds
US8026285B2 (en) 2007-09-04 2011-09-27 Bezwada Biomedical, Llc Control release of biologically active compounds from multi-armed oligomers
US8048980B2 (en) 2007-09-17 2011-11-01 Bezwada Biomedical, Llc Hydrolysable linkers and cross-linkers for absorbable polymers
WO2010148104A2 (en) * 2009-06-16 2010-12-23 L'oreal S.A. Topical compositions containing a polymer for releasing at least one salicylic acid compound
WO2010148101A2 (en) * 2009-06-16 2010-12-23 L'oreal S.A. Topical compositions containing a polymer for releasing at least one salicylic acid compound
US8741317B2 (en) 2010-08-19 2014-06-03 Rutgers, The State University Of New Jersey Slow-degrading polymers comprising salicylic acid for undelayed and sustained drug delivery
US9144579B2 (en) 2012-08-17 2015-09-29 Rutgers, The State University Of New Jersey Polyesters and methods of use thereof
US20140120057A1 (en) 2012-10-25 2014-05-01 Rutgers, The State University Of New Jersey Polymers and methods thereof for wound healing
US9387250B2 (en) 2013-03-15 2016-07-12 Rutgers, The State University Of New Jersey Therapeutic compositions for bone repair
US9862672B2 (en) 2013-05-29 2018-01-09 Rutgers, The State University Of New Jersey Antioxidant-based poly(anhydride-esters)
WO2015191742A1 (en) 2014-06-13 2015-12-17 Rutgers, The State University Of New Jersey Process and intermediates for preparing poly(anhydride-esters)
US10543162B2 (en) 2015-04-10 2020-01-28 Rutgers, The State University Of New Jersey Kojic acid polymers
JP7502186B2 (ja) 2018-02-02 2024-06-18 リップル セラピューティクス コーポレーション ステロイド二量体を含むガラス製剤およびその使用
US12473326B2 (en) 2019-02-01 2025-11-18 Ripple Therapeutics Corporation Crystalline forms of dexamethasone dimers and uses thereof
WO2021007113A1 (en) 2019-07-05 2021-01-14 The Regents Of The University Of Michigan Polymer particles for neutrophil injury
CN115956083A (zh) 2020-05-01 2023-04-11 波纹疗法公司 异二聚体组合物及用于治疗眼部病症的方法
WO2025115004A1 (en) * 2023-11-29 2025-06-05 Yissum Research Development Company Of The Hebrew University Of Jerusalem Ltd. Biodegradable agricultural pesticides

Family Cites Families (64)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE288387C (enExample)
DE288311C (enExample) 1915-10-27
US4062855A (en) 1971-09-27 1977-12-13 University Of Washington Synthetic polymers furnishing controlled release of a biologically active component during degradation
US4363815A (en) * 1975-07-23 1982-12-14 Yu Ruey J Alpha hydroxyacids, alpha ketoacids and their use in treating skin conditions
US4287174A (en) * 1978-03-31 1981-09-01 The Proctor & Gamble Company Anti-ulcer composition
US4298595A (en) * 1978-12-20 1981-11-03 Dynapol Pharmaceutical preparations containing a polymeric agent for releasing 5-aminosalicylic acid or its salts into the gastrointestinal tract
US4906474A (en) 1983-03-22 1990-03-06 Massachusetts Institute Of Technology Bioerodible polyanhydrides for controlled drug delivery
US4888176A (en) 1984-05-21 1989-12-19 Massachusetts Institute Of Technology Controlled drug delivery high molecular weight polyanhydrides
US4757128A (en) 1986-08-01 1988-07-12 Massachusetts Institute Of Technology High molecular weight polyanhydride and preparation thereof
US4483854A (en) * 1983-04-12 1984-11-20 Key Pharmaceuticals, Inc. Systemic treatment of psoriasis using certain salicylates
IL68965A (en) * 1983-06-13 1987-02-27 Rafa Labor Ltd Topical pharmaceutical preparation comprising acetylsalicylic acid for the treatment of dermatological disorders
US4612302A (en) 1983-11-14 1986-09-16 Brigham And Women's Hospital Clinical use of somatostatin analogues
US4891225A (en) 1984-05-21 1990-01-02 Massachusetts Institute Of Technology Bioerodible polyanhydrides for controlled drug delivery
US4886870A (en) * 1984-05-21 1989-12-12 Massachusetts Institute Of Technology Bioerodible articles useful as implants and prostheses having predictable degradation rates
US4684620A (en) 1984-09-04 1987-08-04 Gibson-Stephens Neuropharmaceuticals, Inc. Cyclic polypeptides having mu-receptor specificity
CH666185A5 (en) * 1985-09-16 1988-07-15 Dieter Dr Russmann Salicylic acid or sodium salt - used for treating inflammatory intestinal disorders
CH671402A5 (enExample) 1985-10-02 1989-08-31 Sandoz Ag
DE246341T1 (de) 1986-05-20 1989-03-30 Massachusetts Institute Of Technology, Cambridge, Mass. Bioerodierbare erzeugnisse zur verwendung als implantate oder prothese mit einem voraussehbaren resorbierungsgrad.
US5811128A (en) 1986-10-24 1998-09-22 Southern Research Institute Method for oral or rectal delivery of microencapsulated vaccines and compositions therefor
US5055524A (en) * 1987-07-16 1991-10-08 Ppg Industries, Inc. Polyol-modified polyanhydride curing agent for polyepoxide powder coatings
US4916204A (en) * 1987-07-31 1990-04-10 Massachusetts Institute Of Technology Pure polyanhydride from dicarboxylic acid and coupling agent
US4857311A (en) 1987-07-31 1989-08-15 Massachusetts Institute Of Technology Polyanhydrides with improved hydrolytic degradation properties
US5259968A (en) 1988-02-29 1993-11-09 Exxon Chemical Patents Inc. Dispersant additive comprising the reaction product of a polyanhydride and a mannich condensation product
US4868274A (en) 1988-05-23 1989-09-19 Hoechst Celanese Corp. Polyanhydride from carboxy aryloxy alkanoic acid
US4938949A (en) 1988-09-12 1990-07-03 University Of New York Treatment of damaged bone marrow and dosage units therefor
US5356630A (en) 1989-02-22 1994-10-18 Massachusetts Institute Of Technology Delivery system for controlled release of bioactive factors
AU5287090A (en) 1989-02-28 1990-09-26 Marc N. Benhuri Method and composition for treatment of periodontal disease
US4999417A (en) 1989-03-30 1991-03-12 Nova Pharmaceutical Corporation Biodegradable polymer compositions
DK339289D0 (da) * 1989-07-07 1989-07-07 Dak Lab As Farmaceutisk praeparat
US5487897A (en) 1989-07-24 1996-01-30 Atrix Laboratories, Inc. Biodegradable implant precursor
US4997904A (en) 1989-08-25 1991-03-05 Nova Pharmaceutical Corporation Aromatic polyanhydride compositions
US5660851A (en) * 1989-12-26 1997-08-26 Yissum Research Development Company Of The Hebrew Univ. Of Jerusalem Ocular inserts
JPH06501448A (ja) 1989-12-26 1994-02-17 ノバ　ファーマシューティカル　コーポレイション 無水物プロドラッグ組成物
US5175235A (en) 1990-06-04 1992-12-29 Nova Pharmaceutical Corporation Branched polyanhydrides
US5317079A (en) * 1990-01-19 1994-05-31 Nova Pharmaceutical Corporation Fatty acid terminated polyanhydride
NL9000237A (nl) 1990-01-31 1991-08-16 Re Novative Drugs For Dermatol Topicale farmaceutische composities voor de mondholte en vagina.
US5082925A (en) 1990-08-16 1992-01-21 Ethicon, Inc. Homopolymers and copolymers of salicylate lactones
ATE152147T1 (de) 1990-11-19 1997-05-15 Cornell Res Foundation Inc Hyperverzweigte polyester
US5198572A (en) * 1991-02-04 1993-03-30 General Electric Company Copolymers of dicarboxylic acids and salicylic acids
US5151415A (en) * 1991-05-23 1992-09-29 Dallas Sirany Method of treating a papova-type viral infection
US5264540A (en) 1992-07-20 1993-11-23 Ethicon, Inc. Aromatic polyanhydrides
US5516793A (en) * 1993-04-26 1996-05-14 Avon Products, Inc. Use of ascorbic acid to reduce irritation of topically applied active ingredients
GB9400163D0 (en) 1994-01-06 1994-03-02 Geistlich Soehne Ag Membrane
WO1996003110A1 (fr) * 1994-07-22 1996-02-08 Coletica Acide hydroxyle lipophile, son utilisation en cosmetique et en pharmacie, et son procede de preparation
US5902110A (en) 1995-12-18 1999-05-11 The Block Drug Company Bone regeneration
EP0874643B1 (en) * 1996-02-15 2001-11-21 J. Paul Santerre Bioresponsive pharmacologically-active polymers and articles made therefrom
US5837680A (en) * 1996-02-16 1998-11-17 Children's Medical Center Corporation Pharmaceutical compositions comprising troponin subunits, fragments and analogs thereof and methods of their use to inhibit angiogenesis
US5902599A (en) 1996-02-20 1999-05-11 Massachusetts Institute Of Technology Biodegradable polymer networks for use in orthopedic and dental applications
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
US5955096A (en) * 1996-06-25 1999-09-21 Brown University Research Foundation Methods and compositions for enhancing the bioadhesive properties of polymers using organic excipients
DE69821600T2 (de) 1997-02-18 2005-01-05 Rutgers, The State University Von hydroxysäuren abgeleitete monomere und daraus hergestellte polymere
CA2298824A1 (en) * 1997-08-06 1999-02-18 Smithkline Beecham Corporation Macrophage scavenger receptor antagonists for use in the treatment of cardiovascular diseases
US6468519B1 (en) * 1997-09-10 2002-10-22 Rutgers, The State University Of New Jersey Polyanhydrides with biologically active degradation products
DK1032605T3 (da) 1997-09-10 2008-03-17 Univ Rutgers Polyanhydrider med terapeutisk anvendelige nedbrydningsprodukter
US6486214B1 (en) * 1997-09-10 2002-11-26 Rutgers, The State University Of New Jersey Polyanhydride linkers for production of drug polymers and drug polymer compositions produced thereby
US5882665A (en) * 1997-11-18 1999-03-16 Elizabeth Arden Co., Division Of Conopco, Inc. Phytosphingosine salicylates in cosmetic compositions
DE19754063A1 (de) 1997-12-05 1999-06-10 Bayer Ag Abbau von biologisch abbaubaren Polymeren
US6060212A (en) * 1998-06-11 2000-05-09 Clariant Finance (Bvi) Limited 193 nm positive-working photoresist composition
US6153212A (en) * 1998-10-02 2000-11-28 Guilford Pharmaceuticals Inc. Biodegradable terephthalate polyester-poly (phosphonate) compositions, articles, and methods of using the same
US6685928B2 (en) * 1999-12-07 2004-02-03 Rutgers, The State University Of New Jersey Therapeutic compositions and methods
US20040038948A1 (en) * 1999-12-07 2004-02-26 Uhrich Kathryn E. Therapeutic compositions and methods
US6602915B2 (en) * 2000-07-27 2003-08-05 Rutgers, The State University Of New Jersey Therapeutic azo-compounds for drug delivery
MXPA03000821A (es) * 2000-07-27 2004-03-18 Univ Rutgers Poliesteres y poliamidas terapeuticos.
AU2003251992A1 (en) * 2002-07-17 2004-02-02 Rutgers, The State University Therapeutic devices for patterned cell growth

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