JP2003510071A - Ｐ−糖タンパク質およびその使用 - Google Patents
Ｐ−糖タンパク質およびその使用Info
- Publication number
- JP2003510071A JP2003510071A JP2001526923A JP2001526923A JP2003510071A JP 2003510071 A JP2003510071 A JP 2003510071A JP 2001526923 A JP2001526923 A JP 2001526923A JP 2001526923 A JP2001526923 A JP 2001526923A JP 2003510071 A JP2003510071 A JP 2003510071A
- Authority
- JP
- Japan
- Prior art keywords
- glycoprotein
- seq
- nucleic acid
- pgp
- canine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
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- ZQPPMHVWECSIRJ-KTKRTIGZSA-N oleic acid Chemical compound CCCCCCCC\C=C/CCCCCCCC(O)=O ZQPPMHVWECSIRJ-KTKRTIGZSA-N 0.000 description 1
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- 230000022532 regulation of transcription, DNA-dependent Effects 0.000 description 1
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- MYFATKRONKHHQL-UHFFFAOYSA-N rhodamine 123 Chemical compound [Cl-].COC(=O)C1=CC=CC=C1C1=C2C=CC(=[NH2+])C=C2OC2=CC(N)=CC=C21 MYFATKRONKHHQL-UHFFFAOYSA-N 0.000 description 1
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- 125000002652 ribonucleotide group Chemical group 0.000 description 1
- 125000000548 ribosyl group Chemical group C1([C@H](O)[C@H](O)[C@H](O1)CO)* 0.000 description 1
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- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 239000001509 sodium citrate Substances 0.000 description 1
- NLJMYIDDQXHKNR-UHFFFAOYSA-K sodium citrate Chemical compound O.O.[Na+].[Na+].[Na+].[O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O NLJMYIDDQXHKNR-UHFFFAOYSA-K 0.000 description 1
- 230000009870 specific binding Effects 0.000 description 1
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- QORWJWZARLRLPR-UHFFFAOYSA-H tricalcium bis(phosphate) Chemical compound [Ca+2].[Ca+2].[Ca+2].[O-]P([O-])([O-])=O.[O-]P([O-])([O-])=O QORWJWZARLRLPR-UHFFFAOYSA-H 0.000 description 1
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Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Cell Biology (AREA)
- Engineering & Computer Science (AREA)
- Toxicology (AREA)
- Zoology (AREA)
- Gastroenterology & Hepatology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
- Investigating Or Analysing Biological Materials (AREA)
- Enzymes And Modification Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US15651099P | 1999-09-28 | 1999-09-28 | |
| US60/156,510 | 1999-09-28 | ||
| PCT/US2000/026767 WO2001023540A2 (en) | 1999-09-28 | 2000-09-28 | P-glycoproteins and uses thereof |
Related Child Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011284080A Division JP2012061008A (ja) | 1999-09-28 | 2011-12-26 | Ｐ−糖タンパク質およびその使用 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| JP2003510071A true JP2003510071A (ja) | 2003-03-18 |
| JP2003510071A5 JP2003510071A5 (enExample) | 2007-11-29 |
Family
ID=22559872
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2001526923A Pending JP2003510071A (ja) | 1999-09-28 | 2000-09-28 | Ｐ−糖タンパク質およびその使用 |
| JP2011284080A Withdrawn JP2012061008A (ja) | 1999-09-28 | 2011-12-26 | Ｐ−糖タンパク質およびその使用 |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| JP2011284080A Withdrawn JP2012061008A (ja) | 1999-09-28 | 2011-12-26 | Ｐ−糖タンパク質およびその使用 |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP1220911B1 (enExample) |
| JP (2) | JP2003510071A (enExample) |
| AT (1) | ATE346924T1 (enExample) |
| AU (1) | AU785363B2 (enExample) |
| CA (1) | CA2384981A1 (enExample) |
| DE (1) | DE60032161D1 (enExample) |
| WO (1) | WO2001023540A2 (enExample) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2411101C (en) * | 2000-06-05 | 2018-01-16 | Brigham And Women's Hospital, Inc. | A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof |
| US6855812B2 (en) * | 2001-03-19 | 2005-02-15 | Becton, Dickinson And Company | P-glycoproteins and uses thereof |
| ES2796111T3 (es) | 2008-11-14 | 2020-11-25 | Brigham & Womens Hospital Inc | Métodos terapéuticos relacionados con células madre cancerosas |
| US11542328B2 (en) | 2008-11-14 | 2023-01-03 | The Brigham And Women's Hospital, Inc. | Therapeutic and diagnostic methods relating to cancer stem cells |
| KR20210005118A (ko) | 2018-04-25 | 2021-01-13 | 칠드런'즈 메디컬 센터 코포레이션 | Abcb5 리간드 및 기질 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1993024613A1 (en) * | 1992-05-22 | 1993-12-09 | The United States Government As Represented By The Secretary Of The Department Of Health And Human Services | Improved expression of human multidrug resistance genes and improved selection of cells transduced with such genes |
| US5830697A (en) * | 1997-01-21 | 1998-11-03 | The Board Of Trustees Of The Leland Stanford Junior University | P-glycoprotein mutant resistant to cyclosporin modulation |
-
2000
- 2000-09-28 AT AT00967072T patent/ATE346924T1/de not_active IP Right Cessation
- 2000-09-28 DE DE60032161T patent/DE60032161D1/de not_active Expired - Lifetime
- 2000-09-28 EP EP00967072A patent/EP1220911B1/en not_active Expired - Lifetime
- 2000-09-28 AU AU77327/00A patent/AU785363B2/en not_active Ceased
- 2000-09-28 WO PCT/US2000/026767 patent/WO2001023540A2/en not_active Ceased
- 2000-09-28 JP JP2001526923A patent/JP2003510071A/ja active Pending
- 2000-09-28 CA CA002384981A patent/CA2384981A1/en not_active Abandoned
-
2011
- 2011-12-26 JP JP2011284080A patent/JP2012061008A/ja not_active Withdrawn
Non-Patent Citations (5)
| Title |
|---|
| JPN6010021319, Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９７，２７２（３４），ｐ．２１１６０−６ * |
| JPN6010021321, Ｐｕｅｌ，Ｏ．ｅｔ ａｌ．， "Ａｃｃｅｓｓｉｏｎ： ＡＦ０４５０１６［ｇｉ：２８５２４４０］， Ｄｅｆｉｎｉｔｉｏｎ：Ｃａｎｉｓ ｆａｍｉｌｉａｒｉｓ ｍｕｌｔｉｄｒｕｇ ｒｅｓｉｓｔａｎｃｅ ｐ− * |
| JPN6010021323, Ｃｅｌｌ，１９８６，４７（３），ｐ．３８１−９ * |
| JPN6010021325, Ｃｈｅｎ．Ｃ．Ｊ．ｅｔ ａｌ．， "Ａｃｃｅｓｓｉｏｎ：ＡＦ０１６５３５［ｇｉ：２３５３２６３］， Ｄｅｆｉｎｉｔｉｏｎ：Ｈｏｍｏ ｓａｐｉｅｎｓ Ｐ−ｇｌｙｃｏｐｒｏｔｅｉｎ （ｍｄｒ１） ｍＲＮＡ * |
| JPN6010021326, Ｊ．Ｂｉｏｌ．Ｃｈｅｍ．，１９９７，２７２（９），ｐ．５９７４−８２ * |
Also Published As
| Publication number | Publication date |
|---|---|
| AU785363B2 (en) | 2007-02-01 |
| EP1220911A2 (en) | 2002-07-10 |
| ATE346924T1 (de) | 2006-12-15 |
| AU7732700A (en) | 2001-04-30 |
| JP2012061008A (ja) | 2012-03-29 |
| DE60032161D1 (de) | 2007-01-11 |
| WO2001023540A3 (en) | 2001-10-18 |
| EP1220911B1 (en) | 2006-11-29 |
| WO2001023540A2 (en) | 2001-04-05 |
| CA2384981A1 (en) | 2001-04-05 |
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