CA2384981A1 - P-glycoproteins and uses thereof - Google Patents

P-glycoproteins and uses thereof Download PDF

Info

Publication number
CA2384981A1
CA2384981A1 CA002384981A CA2384981A CA2384981A1 CA 2384981 A1 CA2384981 A1 CA 2384981A1 CA 002384981 A CA002384981 A CA 002384981A CA 2384981 A CA2384981 A CA 2384981A CA 2384981 A1 CA2384981 A1 CA 2384981A1
Authority
CA
Canada
Prior art keywords
leu
ile
ala
gly
val
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
CA002384981A
Other languages
English (en)
French (fr)
Inventor
Penny J. Stocker
Dorothy T. Steimel-Crespi
Charles L. Crespi
Timothy C. Reif
Christopher J. Patten
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gentest Corp
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of CA2384981A1 publication Critical patent/CA2384981A1/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Immunology (AREA)
  • Genetics & Genomics (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Cell Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
CA002384981A 1999-09-28 2000-09-28 P-glycoproteins and uses thereof Abandoned CA2384981A1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US15651099P 1999-09-28 1999-09-28
US60/156,510 1999-09-28
PCT/US2000/026767 WO2001023540A2 (en) 1999-09-28 2000-09-28 P-glycoproteins and uses thereof

Publications (1)

Publication Number Publication Date
CA2384981A1 true CA2384981A1 (en) 2001-04-05

Family

ID=22559872

Family Applications (1)

Application Number Title Priority Date Filing Date
CA002384981A Abandoned CA2384981A1 (en) 1999-09-28 2000-09-28 P-glycoproteins and uses thereof

Country Status (7)

Country Link
EP (1) EP1220911B1 (enExample)
JP (2) JP2003510071A (enExample)
AT (1) ATE346924T1 (enExample)
AU (1) AU785363B2 (enExample)
CA (1) CA2384981A1 (enExample)
DE (1) DE60032161D1 (enExample)
WO (1) WO2001023540A2 (enExample)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2411101C (en) * 2000-06-05 2018-01-16 Brigham And Women's Hospital, Inc. A gene encoding a multidrug resistance human p-glycoprotein homologue on chromosome 7p15-21 and uses thereof
US6855812B2 (en) * 2001-03-19 2005-02-15 Becton, Dickinson And Company P-glycoproteins and uses thereof
ES2796111T3 (es) 2008-11-14 2020-11-25 Brigham & Womens Hospital Inc Métodos terapéuticos relacionados con células madre cancerosas
US11542328B2 (en) 2008-11-14 2023-01-03 The Brigham And Women's Hospital, Inc. Therapeutic and diagnostic methods relating to cancer stem cells
KR20210005118A (ko) 2018-04-25 2021-01-13 칠드런'즈 메디컬 센터 코포레이션 Abcb5 리간드 및 기질

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1993024613A1 (en) * 1992-05-22 1993-12-09 The United States Government As Represented By The Secretary Of The Department Of Health And Human Services Improved expression of human multidrug resistance genes and improved selection of cells transduced with such genes
US5830697A (en) * 1997-01-21 1998-11-03 The Board Of Trustees Of The Leland Stanford Junior University P-glycoprotein mutant resistant to cyclosporin modulation

Also Published As

Publication number Publication date
AU785363B2 (en) 2007-02-01
EP1220911A2 (en) 2002-07-10
ATE346924T1 (de) 2006-12-15
AU7732700A (en) 2001-04-30
JP2012061008A (ja) 2012-03-29
DE60032161D1 (de) 2007-01-11
WO2001023540A3 (en) 2001-10-18
JP2003510071A (ja) 2003-03-18
EP1220911B1 (en) 2006-11-29
WO2001023540A2 (en) 2001-04-05

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Legal Events

Date Code Title Description
EEER Examination request
FZDE Discontinued